Wen Liu

发表

Effective Virtual Screening Strategy toward heme-containing proteins: Identification of novel IDO1 inhibitors.

Qiang Xu, Wenjie Guo, Yihua Zhang, 2019, European journal of medicinal chemistry.

Decrease of Functional Activated T and B Cells and Treatment of Glomerulonephitis in Lupus-Prone Mice Using a Natural Flavonoid Astilbin

Qiang Xu, Yan Shen, Xuefeng Wu, 2015, PloS one.

SHP2 inhibition triggers anti-tumor immunity and synergizes with PD-1 blockade

Qiang Xu, L. Zhong, Yanhong Gu, 2018, Acta pharmaceutica Sinica. B.

Discovery of potent IDO1 inhibitors derived from tryptophan using scaffold-hopping and structure-based design approaches.

Qiang Xu, Wenjie Guo, F. Wang, 2017, European journal of medicinal chemistry.

Apatinib suppresses tumor progression and enhances cisplatin sensitivity in esophageal cancer via the Akt/β-catenin pathway

Qiang Xu, J. Wu, Yanhong Gu, 2020, Cancer Cell International.

NLRP3 protects mice from radiation-induced colon and skin damage via attenuating cGAS-STING signaling.

Wenjie Guo, Wen Liu, Fang-yu Wang, 2021, Toxicology and applied pharmacology.

Andrographolide sulfate inhibited NF-κB activation and alleviated pneumonia induced by poly I:C in mice

Qiang Xu, Yang Sun, Wenjie Guo, 2020, Journal of Pharmacological Sciences.

Andrographolide alleviates Parkinsonism in MPTP‐PD mice via targeting mitochondrial fission mediated by dynamin‐related protein 1

Qiang Xu, Z. Qin, Yang Sun, 2019, British journal of pharmacology.

T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice

Qiang Xu, Yanhong Gu, Yang Sun, 2016, Oncotarget.

A Novel Disease-Modifying Antirheumatic Drug, Iguratimod, Ameliorates Murine Arthritis by Blocking IL-17 Signaling, Distinct from Methotrexate and Leflunomide

Qiang Xu, C. Qian, Yanhong Gu, 2013, The Journal of Immunology.

This information is current as Distinct from Methotrexate and Leflunomide Arthritis by Blocking IL-17 Signaling, Drug, Iguratimod, Ameliorates Murine A Novel Disease-Modifying Antirheumatic

C. Qian, Yan Shen, Yangyong Sun, 2013 .

Targeting Peroxiredoxin 1 by a Curcumin Analogue, AI-44, Inhibits NLRP3 Inflammasome Activation and Attenuates Lipopolysaccharide-Induced Sepsis in Mice

Qiang Xu, Yang Sun, Wei Zheng, 2018, The Journal of Immunology.

Combination of apatinib with apo-IDO1 inhibitor for the treatment of colorectal cancer.

Qiang Xu, Wenjie Guo, Yi He, 2022, International immunopharmacology.

5-Androstenediol prevents radiation injury in mice by promoting NF-κB signaling and inhibiting AIM2 inflammasome activation.

Wenjie Guo, Wen Liu, Xi-Xu Zhu, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways

Qiang Xu, Yang Sun, Wenjie Guo, 2016, Acta pharmaceutica Sinica. B.

Andrographolide sulfonate ameliorates experimental colitis in mice by inhibiting Th1/Th17 response.

Qiang Xu, Yanhong Gu, Xuefeng Wu, 2014, International immunopharmacology.

Fumigaclavine C ameliorates dextran sulfate sodium-induced murine experimental colitis via NLRP3 inflammasome inhibition.

Qiang Xu, Yang Sun, Wenjie Guo, 2015, Journal of pharmacological sciences.

Mitochondria-Dependent Apoptosis of Con A-Activated T Lymphocytes Induced by Asiatic Acid for Preventing Murine Fulminant Hepatitis

Qiang Xu, C. Qian, Yan Shen, 2012, PloS one.

MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation

Qiang Xu, Yan Shen, Xuefeng Wu, 2016, Oncotarget.

SHP2-mediated mitophagy boosted by lovastatin in neuronal cells alleviates parkinsonism in mice

Qiang Xu, L. Ouyang, Yang Sun, 2021, Signal Transduction and Targeted Therapy.

Apo-Form Selective Inhibition of IDO for Tumor Immunotherapy

Qiang Xu, Wenjie Guo, Shushan Ge, 2022, The Journal of Immunology.

Rotating magnetic field delays human umbilical vein endothelial cell aging and prolongs the lifespan of Caenorhabditis elegans

Yang Sun, Xiaomei Wang, Gaixia Xu, 2019, Aging.

Spirodalesol analog 8A inhibits NLRP3 inflammasome activation and attenuates inflammatory disease by directly targeting adaptor protein ASC

A. Zhang, Wenjie Guo, Wen Liu, 2022, The Journal of biological chemistry.

Mitochondria-dependent apoptosis of activated T lymphocytes induced by astin C, a plant cyclopeptide, for preventing murine experimental colitis.

Qiang Xu, G. Zeng, Yan Shen, 2011, Biochemical pharmacology.

A novel benzo[d]imidazole derivate prevents the development of dextran sulfate sodium-induced murine experimental colitis via inhibition of NLRP3 inflammasome.

Qiang Xu, Yanhong Gu, Yan Shen, 2013, Biochemical pharmacology.

Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation

Qiang Xu, Yang Sun, Wenjie Guo, 2016, Oncotarget.

Andrographolide reversed 5-FU resistance in human colorectal cancer by elevating BAX expression.

Qiang Xu, Yanhong Gu, Yang Sun, 2016, Biochemical pharmacology.

Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer

Qiang Xu, Yanhong Gu, Yan Shen, 2014, Autophagy.

Water-soluble andrographolide sulfonate exerts anti-sepsis action in mice through down-regulating p38 MAPK, STAT3 and NF-κB pathways.

Qiang Xu, C. Qian, Gong Chen, 2012, International immunopharmacology.

Discovery of imidazoleisoindole derivatives as potent IDO1 inhibitors: Design, synthesis, biological evaluation and computational studies.

Qiang Xu, Wenjie Guo, F. Wang, 2017, European journal of medicinal chemistry.

Andrographolide sulfonate ameliorates chronic colitis induced by TNBS in mice via decreasing inflammation and fibrosis.

Qiang Xu, Wenjie Guo, Wen Liu, 2020, International immunopharmacology.

Asiatic acid ameliorates dextran sulfate sodium-induced murine experimental colitis via suppressing mitochondria-mediated NLRP3 inflammasome activation.

Qiang Xu, Yang Sun, Wenjie Guo, 2015, International immunopharmacology.

Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis

Qiang Xu, G. Feng, Yanhong Gu, 2017, Nature Communications.

Blocking initial infiltration of pioneer CD8+ T‐cells into the CNS via inhibition of SHP‐2 ameliorates experimental autoimmune encephalomyelitis in mice

Qiang Xu, Yan Shen, Yang Sun, 2014, British journal of pharmacology.

Silymarin suppressed lung cancer growth in mice via inhibiting myeloid-derived suppressor cells.

Wenjie Guo, Wen Liu, Xi-Xu Zhu, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Loss of SHP-2 activity in CD4+ T cells promotes melanoma progression and metastasis

Qiang Xu, Lu Wang, Yanhong Gu, 2013, Scientific Reports.

Andrographolide potentiates PD-1 blockade immunotherapy by inhibiting COX2-mediated PGE2 release.

Qiang Xu, Yang Sun, Lixuan Liu, 2020, International immunopharmacology.

DNA damage repair promotion in colonic epithelial cells by andrographolide downregulated cGAS‒STING pathway activation and contributed to the relief of CPT-11-induced intestinal mucositis

Qiang Xu, J. Wu, Yanhong Gu, 2021, Acta pharmaceutica Sinica. B.

SHP2-Mediated Inhibition of DNA Repair Contributes to cGAS–STING Activation and Chemotherapeutic Sensitivity in Colon Cancer

Qiang Xu, J. Wu, Yanhong Gu, 2021, Cancer Research.

Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels

Qiang Xu, G. Feng, Yang Sun, 2020, The Journal of Biological Chemistry.

Discovery of secondary sulphonamides as IDO1 inhibitors with potent antitumour effects in vivo

Qiang Xu, Wenjie Guo, Shushan Ge, 2020, Journal of enzyme inhibition and medicinal chemistry.

Carnosic acid enhances the anti-lung cancer effect of cisplatin by inhibiting myeloid-derived suppressor cells.

Qiang Xu, Yue Hu, Wen Liu, 2018, Chinese journal of natural medicines.

Andrographolide triggers autophagy-mediated inflammation inhibition and attenuates chronic unpredictable mild stress (CUMS)-induced depressive-like behavior in mice.

Wenjie Guo, Xiao Yuan, Wen Liu, 2019, Toxicology and applied pharmacology.

Andrographolide alleviates parkinsonism in MPTP-PD mice via targeting DRP1-mediated mitochondrial fission.

Qiang Xu, Z. Qin, Yang Sun, 2019, British journal of pharmacology.

Apatinib suppresses tumor progression and enhances cisplatin sensitivity in esophageal cancer via the Akt/β-catenin pathway

Qiang Xu, J. Wu, Yanhong Gu, 2020, Cancer Cell International.

Andrographolide sulfonate improves Alzheimer-associated phenotypes and mitochondrial dysfunction in APP/PS1 transgenic mice.

Qiang Xu, Yang Sun, Wenjie Guo, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Spirodalesol, an NLRP3 Inflammasome Activation Inhibitor.

Qiang Xu, Nan Jiang, R. Tan, 2016, Organic letters.

Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis

Qiang Xu, G. Feng, Yanhong Gu, 2017, Nature Communications.

A WD-GA-LSSVM model for rainfall-triggered landslide displacement prediction

Qiang Xu, Shuqi Ma, Xing Zhu, 2018, Journal of Mountain Science.