K. Shaw

发表

Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.

M. Hilgers, M. Teng, M. Cunningham, 2013, Journal of medicinal chemistry.

Use of plasmid analysis and determination of aminoglycoside-modifying enzymes to characterize isolates from an outbreak of methicillin-resistant Staphylococcus aureus

P. M. Terry, C. Licitra, P. Terry, 1989, Journal of clinical microbiology.

_-Lactams for the Treatment of Biofilm-Associated Infections

K. Bush, K. Shaw, I. Dodge, 2005 .

DNA Microarray Expression Analysis in Antibacterial Drug Discovery

K. Shaw, B. Morrow, 2002 .

Escherichia coli K-12 auxotrophs induced by insertion of the transposable element Tn5.

K. Shaw, C. M. Berg, 1979, Genetics.

Evernimicin (SCH27899) Inhibits a Novel Ribosome Target Site: Analysis of 23S Ribosomal DNA Mutants

D. Loebenberg, K. Klugman, K. Shaw, 2000, Antimicrobial Agents and Chemotherapy.

Anthracimycin Activity Against Contemporary Methicillin-Resistant Staphylococcus aureus

V. Nizet, M. Hensler, N. Haste, 2014, The Journal of Antibiotics.

Enhanced Efflux Pump Expression in Candida Mutants Results in Decreased Manogepix Susceptibility

M. Kapoor, L. Cowen, L. Whitesell, 2020, Antimicrobial Agents and Chemotherapy.

Effects of altered 5'-flanking sequences on the in vivo expression of a Saccharomyces cerevisiae tRNATyr gene

M. Olson, K. Shaw, 1984, Molecular and cellular biology.

Comparison of the Essential Cellular Functions of the Two murA Genes of Bacillus anthracis

R. Haselbeck, M. Hilgers, K. Shaw, 2008, Antimicrobial Agents and Chemotherapy.

Antibiotic susceptibility of multiply resistant Pseudomonas aeruginosa isolated from patients with cystic fibrosis, including candidates for transplantation.

A. Prince, L. Saiman, H. Neu, 1996, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Linezolid-Resistant Staphylococcus aureus Strain 1128105, the First Known Clinical Isolate Possessing the cfr Multidrug Resistance Gene

R. Goering, J. Deane, D. Sahm, 2014, Antimicrobial Agents and Chemotherapy.

Analysis of β‐glucans and chitin in a Saccharomyces cerevisiae cell wall mutant using high‐performance liquid chromatography

B. Didomenico, K. Shaw, P. Mann, 1994 .

Cloning and Characterization of KNR4, a Yeast Gene Involved in (1,3)-13-Glucan Synthesis

Z. Hong, B. Didomenico, K. Shaw, 2022 .

Salmonella typhimurium mutants defective in acetohydroxy acid synthases I and II

K. Shaw, C. M. Berg, T. J. Sobol, 1980, Journal of bacteriology.

Improved synthesis of the sodium salt of dl-α,β-dihydroxyisovaleric acid

W. Bailey, K. Shaw, C. M. Berg, 1980 .

Improved synthesis of the sodium salt of DL-alpha, beta-dihydroxyisovaleric acid.

W. Bailey, K. Shaw, C. M. Berg, 1980, Analytical biochemistry.

Regulated Secretion of MuGM-CSF in Saccharomyces cerevisiae via GAL1:MFα1 Prepro Sequences

S. Narula, B. Frommer, P. Leibowitz, 1988 .

GR-2397: Review of the Novel Siderophore-like Antifungal Agent for the Treatment of Invasive Aspergillosis

K. Shaw, 2022, Journal of fungi.

Calcineurin Inhibitors Synergize with Manogepix to Kill Diverse Human Fungal Pathogens

M. Kapoor, L. Cowen, L. Whitesell, 2022, Journal of fungi.

Therapeutic Potential of Fosmanogepix (APX001) for Intra-abdominal Candidiasis: from Lesion Penetration to Efficacy in a Mouse Model

M. Zimmerman, V. Dartois, D. Perlin, 2021, Antimicrobial Agents and Chemotherapy.

PHYSIOLOGICAL CHARACTERIZATION OF POLAR Tn5-INDUCED EVIDENCE FOR AN INTERNAL PROMOTER IN THE ilvOGEDA OPERON' ISOLEUCINE-VALINE AUXOTROPHS IN ESCHERZCHZA COLI K-12:

K. Shaw, C. M. Berg, J. Vender, 1979 .

Efficacy of APX2039 in a Rabbit Model of Cryptococcal Meningitis

Laura G. Dubois, J. Perfect, J. Thompson, 2022, mBio.

Mutations in Ribosomal Protein L3 Are Associated with Oxazolidinone Resistance in Staphylococci of Clinical Origin

M. Hilgers, Jeffrey B Locke, K. Shaw, 2009, Antimicrobial Agents and Chemotherapy.

The ilvG gene is expressed in Escherichia coli K-12.

D. Berg, K. Shaw, C. M. Berg, 1980, Gene.

Fosmanogepix: A Review of the First-in-Class Broad Spectrum Agent for the Treatment of Invasive Fungal Infections

A. Ibrahim, K. Shaw, 2020, Journal of fungi.

Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis

M. H. Lee, D. Perlin, Steven Park, 2018, Antimicrobial Agents and Chemotherapy.

The Combination Treatment of Fosmanogepix and Liposomal Amphotericin B Is Superior to Monotherapy in Treating Experimental Invasive Mold Infections

Yiyou Gu, A. Ibrahim, K. Shaw, 2022, Antimicrobial agents and chemotherapy.

Distinguishing On-Target versus Off-Target Activity in Early Antibacterial Drug Discovery Using a Macromolecular Synthesis Assay

M. Cunningham, Bryan P. Kwan, K. Shaw, 2013, Journal of biomolecular screening.

Genetic Environment and Stability of cfr in Methicillin-Resistant Staphylococcus aureus CM05

A. Mankin, Jeffrey B Locke, K. Shaw, 2011, Antimicrobial Agents and Chemotherapy.

Cloning and characterization of a 3-N-aminoglycoside acetyltransferase gene, aac(3)-Ib, from Pseudomonas aeruginosa

C. Schaffner, K. Shaw, R. Hare, 1995, Antimicrobial agents and chemotherapy.

Nucleotide sequence analysis and DNA hybridization studies of the ant(4')-IIa gene from Pseudomonas aeruginosa

P. Rather, K. Shaw, R. Hare, 1993, Antimicrobial Agents and Chemotherapy.

APX 001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis

M. Kapoor, Yiyou Gu, K. Shaw, 2019 .

APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis

M. Kapoor, Yiyou Gu, A. Ibrahim, 2018, Antimicrobial Agents and Chemotherapy.

In Vitro Activity of Manogepix against Multidrug-Resistant and Panresistant Candida auris from the New York Outbreak

M. Kapoor, K. Shaw, V. Chaturvedi, 2020, Antimicrobial Agents and Chemotherapy.

Evaluation of in vitro activity of manogepix against multidrug-resistant and pan-resistant Candida auris from the New York Outbreak

M. Kapoor, K. Shaw, V. Chaturvedi, 2020, bioRxiv.

APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia

M. Kapoor, J. Fierer, John Covel, 2018, Antimicrobial Agents and Chemotherapy.

In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus

J. Perfect, M. Kapoor, W. Schell, 2018, Antimicrobial Agents and Chemotherapy.

In Vitro and In Vivo Evaluation of the Antifungal Activity of APX001A/APX001 against Candida auris

M. Ghannoum, K. Shaw, C. Hager, 2018, Antimicrobial Agents and Chemotherapy.

First-in-Human Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

M. Hodges, K. Shaw, R. Mansbach, 2017 .

Phase 1 Study to Assess Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Doses of APX001 and to Investigate the Effect of Food on APX001 Bioavailability

M. Hodges, K. Shaw, R. Mansbach, 2017 .

Absorption, Distribution, and Excretion of 14C-APX001 after Single-Dose Administration to Rats and Monkeys

M. Hodges, K. Shaw, M. E. Fitzsimmons, 2017, Open Forum Infectious Diseases.

The oxazolidinones: past, present, and future

K. Shaw, M. R. Barbachyn, 2011, Annals of the New York Academy of Sciences.

A Novel Family of Escherichia coli Toxin-Antitoxin Gene Pairs

Jason M. Brown, K. Shaw, 2003, Journal of bacteriology.

Cloning and characterization of KNR4, a yeast gene involved in (1,3)-beta-glucan synthesis

B. Didomenico, N. Brown, K. Shaw, 1994, Molecular and cellular biology.

Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.

Mark Stidham, Mark Hilgers, John Finn, 2011, Bioorganic & medicinal chemistry letters.

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: development of inhibitors with broad spectrum, Gram-negative antibacterial activity.

Toan B. Nguyen, Sergio E. Wong, F. Lightstone, 2013, Bioorganic & medicinal chemistry letters.

Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains.

John J. M. Wiener, Cheryl A. Grice, M. Hack, 2007, Bioorganic & medicinal chemistry letters.

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: synthesis and preliminary SAR analysis.

John J. M. Wiener, Cheryl A. Grice, M. Hack, 2007, Bioorganic & medicinal chemistry letters.

Analysis of commercial kidney stone probiotic supplements.

S. Daniel, J. Knight, K. Shaw, 2015, Urology.

Diversity of aminoglycoside resistance inEnterobacter cloacae in Greece

T. Pitt, M. Nikolopoulou, A. Tsakris, 1992, European Journal of Clinical Microbiology and Infectious Diseases.

Detection of the High-Level Aminoglycoside Resistance Gene aph(2")-Ib in Enterococcus faecium

M. Zervos, J. Chow, D. Clewell, 2000, Antimicrobial Agents and Chemotherapy.

The most frequently occurring aminoglycoside resistance mechanisms--combined results of surveys in eight regions of the world. The Aminoglycoside Resistance Study Groups.

K. Shaw, F. Sabatelli, R. Hare, 1995, Journal of chemotherapy.

Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.

P. Rather, K. Shaw, R. Hare, 1993, Microbiological reviews.

Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes

P. Rather, K. Shaw, R. Hare, 1993 .

Correlation between aminoglycoside resistance profiles and DNA hybridization of clinical isolates

S. Kocsi, K. Shaw, P. Mann, 1991, Antimicrobial Agents and Chemotherapy.

Resistance to aminoglycoside antibiotics in gram-negative bacilli and staphylococci isolated from blood. Report from a European collaborative study. The ESGAR Study Group (European Study Group on Antibiotic Resistance).

K. Shaw, K. Dornbusch, R. Hare, 1990, The Journal of antimicrobial chemotherapy.

Characterization and transcriptional regulation of the 2'-N-acetyltransferase gene from Providencia stuartii

P. Rather, K. Shaw, R. Hare, 1993, Journal of bacteriology.

Characterization of the chromosomal aac(6')-Ic gene from Serratia marcescens

P. Rather, G. Petrikkos, K. Shaw, 1992, Antimicrobial Agents and Chemotherapy.

Isolation, characterization, and DNA sequence analysis of an AAC(6')-II gene from Pseudomonas aeruginosa

K. Shaw, R. Hare, C. Cramer, 1989, Antimicrobial Agents and Chemotherapy.

Efficacy and Pharmacokinetics of Fosmanogepix (APX001) in the Treatment of Candida Endophthalmitis and Hematogenous Meningoencephalitis in Nonneutropenic Rabbits

M. Finkelman, T. Walsh, M. Hodges, 2020, Antimicrobial Agents and Chemotherapy.

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis

Yiyou Gu, A. Ibrahim, K. Shaw, 2019, Antimicrobial Agents and Chemotherapy.

Antibiotic Susceptibility Profiles ofEscherichia coli Strains Lacking Multidrug Efflux Pump Genes

Christina Cramer, B. Didomenico, J. Greene, 2001, Antimicrobial Agents and Chemotherapy.

In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains

J. Finn, K. Shaw, J. Finn, 2008, Antimicrobial Agents and Chemotherapy.

Efficacy of Delayed Therapy with Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis

G. Catano, K. Shaw, T. Patterson, 2019, Antimicrobial Agents and Chemotherapy.

Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus

S. Filler, A. Ibrahim, K. Shaw, 2020, Antimicrobial Agents and Chemotherapy.

Evaluation of Resistance Development to the Gwt1 Inhibitor Manogepix (APX001A) in Candida Species

M. Kapoor, M. Moloney, K. Shaw, 2019, Antimicrobial Agents and Chemotherapy.

1954. In vivo Efficacy of Delayed Therapy with the Novel Inositol Acyltransferase Inhibitor Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis

G. Catano, K. Shaw, T. Patterson, 2019, Open Forum Infectious Diseases.

Genomics and Antimicrobial Drug Discovery

G. Vovis, D. Moir, K. Shaw, 1999, Antimicrobial Agents and Chemotherapy.

The most frequent aminoglycoside resistance mechanisms--changes with time and geographic area: a reflection of aminoglycoside usage patterns? Aminoglycoside Resistance Study Groups.

D. Shlaes, K. Shaw, Y. Glupczynski, 1997, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Aminoglycoside Resistance Genesaph(2")-Ib and aac(6′)-Im Detected Together in Strains of both Escherichia coli andEnterococcus faecium

J. Chow, D. Clewell, S. Lerner, 2001, Antimicrobial Agents and Chemotherapy.

Cloning and characterization of an aminoglycoside 6'-N-acetyltransferase gene from Citrobacter freundii which confers an altered resistance profile

K. Shaw, R. Hare, G. Miller, 1997, Antimicrobial agents and chemotherapy.

The changing nature of aminoglycoside resistance mechanisms and the role of isepamicin--a new broad-spectrum aminoglycoside. The Aminoglycoside Resistance Study Groups.

K. Shaw, F. Sabatelli, R. Hare, 1995, Journal of chemotherapy.

Nucleotide Sequence Analysis andDNA Hybridization Studies of theant(4')-IIa GenefromPseudomonas aeruginosa

S. Hare, H. Miller, K. Shaw, 1993 .

Cloning and DNA sequence analysis of an aac(3)-Vb gene from Serratia marcescens

P. Rather, K. Shaw, R. Hare, 1992, Antimicrobial Agents and Chemotherapy.

Genetic analysis of bacterial acetyltransferases: identification of amino acids determining the specificities of the aminoglycoside 6'-N-acetyltransferase Ib and IIa proteins

P. Rather, K. Shaw, P. Mann, 1992, Journal of bacteriology.

Elevated Linezolid Resistance in Clinical cfr-Positive Staphylococcus aureus Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3

J. Stein, M. Hilgers, Gracia Morales, 2010, Antimicrobial Agents and Chemotherapy.

Structure-based design of new dihydrofolate reductase antibacterial agents: 7-(benzimidazol-1-yl)-2,4-diaminoquinazolines.

M. Hilgers, M. Cunningham, Bryan P. Kwan, 2014, Journal of medicinal chemistry.

Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing the cfr Methyltransferase Gene or Ribosomal Mutations

J. Stein, M. Hilgers, Gracia Morales, 2010, Antimicrobial Agents and Chemotherapy.

Evaluation of the metS and murB Loci for Antibiotic Discovery Using Targeted Antisense RNA Expression Analysis in Bacillus anthracis

R. Haselbeck, M. Hilgers, K. Shaw, 2007, Antimicrobial Agents and Chemotherapy.

Efflux Pump Genes Strains Lacking Multidrug Escherichia coli Antibiotic Susceptibility Profiles of

B. Didomenico, J. Greene, N. Jiwani, 2001 .

Radioenzymatic assay for the acetohydroxy acid synthase-catalyzed synthesis of α-aceto-α-hydroxybutyrate

K. Shaw, C. M. Berg, 1980 .

Results of the surveillance of Tedizolid activity and resistance program: in vitro susceptibility of gram-positive pathogens collected in 2011 and 2012 from the United States and Europe.

J. Deane, D. Sahm, Jeffrey B Locke, 2015, Diagnostic microbiology and infectious disease.

Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2013, Nucleic acids research.

Mutations in Ribosomal Protein L16 Conferring Reduced Susceptibility to Evernimicin (SCH27899): Implications for Mechanism of Action

K. Klugman, K. Shaw, R. Hare, 2000, Antimicrobial Agents and Chemotherapy.

Evernimicin Binds Exclusively to the 50S Ribosomal Subunit and Inhibits Translation in Cell-Free Systems Derived from both Gram-Positive and Gram-Negative Bacteria

K. Shaw, P. Mann, P. McNicholas, 2000, Antimicrobial Agents and Chemotherapy.

, David Gram-Positive and Gram-Negative Bacteria in Cell-Free Systems Derived from both Ribosomal Subunit and Inhibits Translation Evernimicin Binds Exclusively to the 50 S

K. Shaw, P. Mann, P. McNicholas, 2000 .

Low Fitness Cost of the Multidrug Resistance Gene cfr

A. Mankin, Jeffrey B Locke, K. Shaw, 2011, Antimicrobial Agents and Chemotherapy.

Organization and regulation of the ilvGEDA operon in Salmonella typhimurium LT2

K. Shaw, C. M. Berg, 1981, Journal of bacteriology.

Substrate channeling: alpha-ketobutyrate inhibition of acetohydroxy acid synthase in Salmonella typhimurium

K. Shaw, C. M. Berg, 1980, Journal of bacteriology.

Simultaneous analysis of host and pathogen interactions during an in vivo infection reveals local induction of host acute phase response proteins, a novel bacterial stress response, and evidence of a host‐imposed metal ion limited environment

A. Vitiello, Xuejun Liu, K. Shaw, 2004, Cellular microbiology.

Tricyclic GyrB/ParE (TriBE) Inhibitors: A New Class of Broad-Spectrum Dual-Targeting Antibacterial Agents

Felice C. Lightstone, Toan B. Nguyen, Sergio E. Wong, 2013, PloS one.

Transcriptional profiling and drug discovery.

K. Shaw, B. Morrow, Karen Joy Shaw, 2003, Current opinion in pharmacology.

A novel gentamicin resistance gene in Enterococcus

S. Tsai, M. Zervos, J. Chow, 1997, Antimicrobial agents and chemotherapy.

TRANSPOSON INDUCED MUTATIONS IN THE GENES CODING FOR THE ACETOHYDROXY ACID SYNTHASE (AHAS) ISOZYMES IN Salmonella typhimurium

K. Shaw, C. M. Berg, 1980 .

Macromolecular Synthesis Assay Distinguishing On-Target versus Off-Target Activity in Early Antibacterial Drug Discovery Using a

L. Cunningham, Bryan P. Kwan, K. Shaw, 2013 .

Comparison of the Changes in Global Gene Expression of Escherichia coli Induced by Four Bactericidal Agents

Xuejun Liu, A. Bittner, Nancy Miller, 2003, Journal of Molecular Microbiology and Biotechnology.

HSa of Staphylococcus aureus, a new member of the HU family of bacterial histone-like proteins.

M. Gennaro, K. Shaw, S. Viter, 1999, Research in microbiology.

Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)

M. Hilgers, Jeffrey B Locke, K. Shaw, 2009, Antimicrobial Agents and Chemotherapy.

Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.

T. Steitz, M. Rodnina, A. Mankin, 2014, Molecular cell.

Tedizolid for the management of human infections: in vitro characteristics.

Jeffrey B Locke, K. Shaw, K. Bartizal, 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Identification and Characterization of Linezolid-Resistant cfr-Positive Staphylococcus aureus USA300 Isolates from a New York City Medical Center

R. Goering, S. Jenkins, J. Deane, 2014, Antimicrobial Agents and Chemotherapy.

Physiological characterization of polar Tn5-induced isoleucine-valine auxotrophs in Escherichia coli K.12: evidence for an internal promoter in the ilvOGEDA operon.

K. Shaw, C. M. Berg, J. Vender, 1979, Genetics.

Manogepix, the Active Moiety of the Investigational Agent Fosmanogepix, Demonstrates In Vitro Activity against Members of the Fusarium oxysporum and Fusarium solani Species Complexes

H. Badali, A. Ibrahim, K. Shaw, 2021, Antimicrobial Agents and Chemotherapy.

Genetic Footprinting in Bacteria

J. Greene, K. Baradaran, L. Guzmán, 2001, Journal of bacteriology.

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.

Toan B. Nguyen, Sergio E. Wong, J. Nix, 2013, Bioorganic & medicinal chemistry letters.

Synthesis of analogs of the Gwt1 inhibitor manogepix (APX001A) and in vitro evaluation against Cryptococcus spp.

M. Kapoor, M. Moloney, John Covel, 2019, Bioorganic & medicinal chemistry letters.

Galactomannan Is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis

Yiyou Gu, A. Ibrahim, K. Shaw, 2019, Antimicrobial Agents and Chemotherapy.

In Vitro Activity of APX2041, a New Gwt1 Inhibitor, and In Vivo Efficacy of the Prodrug APX2104 against Aspergillus fumigatus

M. Kapoor, Yohannes G. Asfaw, W. Steinbach, 2021, Antimicrobial agents and chemotherapy.

Analysis of the aac(3)-VIa gene encoding a novel 3-N-acetyltransferase

P. Rather, K. Shaw, P. Mann, 1993, Antimicrobial Agents and Chemotherapy.

726. APX001 (Fosmanogepix) Is Effective in an Immunosuppressed Mouse Model of Rhizopus oryzae Infection

Yiyou Gu, A. Ibrahim, K. Shaw, 2019, Open Forum Infectious Diseases.

APX001A Protects Immunosuppressed Mice from Rhizopus delemar Infection

S. Filler, A. Ibrahim, K. Shaw, 2017, Open Forum Infectious Diseases.

Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers

M. Hodges, K. Shaw, M. Tawadrous, 2023, Antimicrobial agents and chemotherapy.

Title : Fosmanogepix ( APX 001 ) is Effective in the Treatment of Pulmonary Murine 1 Mucormycosis Due to Rhizopus arrhizus 2 3 Running title : Efficacy of fosmanogepix against mucormycosis 4 5 Byline :

S. Filler, A. Ibrahim, K. Shaw, 2020 .

Affinity Capillary Electrophoresis for the Screening of Novel Antimicrobial Targets

W. Pierceall, L. Engle, D. Hughes, 2004, Journal of biomolecular screening.

Identification of three additional femAB-like open reading frames in Staphylococcus aureus.

B. Berger-Bächi, K. Shaw, S. Rohrer, 1999, FEMS microbiology letters.

Overview of whole-genome essentiality analysis.

K. Shaw, 2008, Methods in molecular biology.

Efficacy of Oral APX001 in a Murine Model of Cryptococcal Meningitis

J. Perfect, W. Schell, C. Giamberardino, 2017, Open Forum Infectious Diseases.

APX001A Protects Immunosuppressed Mice from Rhizopus delemar Infection

S. Filler, A. Ibrahim, K. Shaw, 2017, Open Forum Infectious Diseases.

In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains

J. Finn, K. Shaw, G. Zurenko, 2008, Antimicrobial Agents and Chemotherapy.