J. Finn

发表

Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.

M. Hilgers, M. Teng, M. Cunningham, 2013, Journal of medicinal chemistry.

A widely useful chiral stationary phase for the high-performance liquid chromatography separation of enantiomers

J. Finn, B. Hamper, W. H. Pirkle, 1981 .

Application of SBDD to the discovery of new antibacterial drugs.

J. Finn, 2012, Methods in molecular biology.

Regulation of mprF by Antisense RNA Restores Daptomycin Susceptibility to Daptomycin-Resistant Isolates of Staphylococcus aureus

R. Haselbeck, M. Conrad, A. Rubio, 2010, Antimicrobial Agents and Chemotherapy.

Comparison of the Essential Cellular Functions of the Two murA Genes of Bacillus anthracis

R. Haselbeck, M. Hilgers, K. Shaw, 2008, Antimicrobial Agents and Chemotherapy.

Discovery of a potent and selective series of pyrazole bacterial methionyl-tRNA synthetase inhibitors.

P. Gallant, Elsa Mak, J. Finn, 2003, Bioorganic & medicinal chemistry letters.

PREPARATIVE RESOLUTION OF RACEMATES ON A CHIRAL LIQUID CHROMATOGRAPHY COLUMN

J. Finn, W. H. Pirkle, 1982 .

Array synthesis of novel lipodepsipeptide.

J. Finn, J. Silverman, I. Parr, 2003, Bioorganic & medicinal chemistry letters.

Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent.

Sung‐Hwa Yoon, Ju-Young Park, J. Finn, 2011, European journal of medicinal chemistry.

Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis

D. Hosfield, R. Swanson, A. Brooun, 2004 .

Broad spectrum resolution of optical isomers using chiral high-performance liquid chromatographic bonded phases

J. Finn, W. H. Pirkle, D. House, 1980 .

A widely useful chiral stationary phase for the high-performance liquid chromatography separation of enantiomers

J. Finn, B. Hamper, W. H. Pirkle, 1981 .

Convergent, enantiospecific total synthesis of the hypocholesterolemic agent (+)-compactin.

J. Finn, P. Grieco, R. Zelle, 1986, Journal of the American Chemical Society.

Synthesis of .alpha.-hydroxycarbonyl compounds (acyloins): direct oxidation of enolates using 2-sulfonyloxaziridines

J. Finn, F. A. Davis, L. C. Vishwakarma, 1984 .

A series of heterocyclic inhibitors of phenylalanyl-tRNA synthetases with antibacterial activity.

J. Finn, J. Silverman, D. Keith, 2004, Bioorganic & medicinal chemistry letters.

A series of spirocyclic analogues as potent inhibitors of bacterial phenylalanyl-tRNA synthetases.

J. Finn, J. Silverman, D. Keith, 2004, Bioorganic & medicinal chemistry letters.

Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.

Mark Stidham, Mark Hilgers, John Finn, 2011, Bioorganic & medicinal chemistry letters.

A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase.

P. Gallant, J. Finn, J. Silverman, 2001, Bioorganic & medicinal chemistry letters.

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: development of inhibitors with broad spectrum, Gram-negative antibacterial activity.

Toan B. Nguyen, Sergio E. Wong, F. Lightstone, 2013, Bioorganic & medicinal chemistry letters.

Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent.

Sung‐Hwa Yoon, Ju-Young Park, J. Finn, 2011, European journal of medicinal chemistry.

CHIRAL HIGH-PRESSURE LIQUID CHROMATOGRAPHIC STATIONARY PHASES. 3. GENERAL RESOLUTION OF ARYLALKYLCARBINOLS

J. Finn, W. H. Pirkle, 1981 .

Total synthesis of the hypocholesterolemic agent (+)-compactin

J. Finn, P. Grieco, R. Zelle, 1983 .

6 – Separation of Enantiomers by Liquid Chromatographic Methods

J. Finn, W. H. Pirkle, 1983 .

A Facile Method for the Asymmetric Synthesis of .alpha.-Methyltryptophan

J. Finn, Li-Jun Zhang, 1995 .

Useful routes to 9-anthryl ethers and sulfides

J. Finn, W. H. Pirkle, 1983 .

In Vitro Activity of TR-700, the Antibacterial Moiety of the Prodrug TR-701, against Linezolid-Resistant Strains

J. Finn, K. Shaw, J. Finn, 2008, Antimicrobial Agents and Chemotherapy.

Structural Basis for Bisphosphonate-mediated Inhibition of Isoprenoid Biosynthesis*

D. Hosfield, R. Swanson, D. Dougan, 2004, Journal of Biological Chemistry.

Structure-based design of new dihydrofolate reductase antibacterial agents: 7-(benzimidazol-1-yl)-2,4-diaminoquinazolines.

M. Hilgers, M. Cunningham, Bryan P. Kwan, 2014, Journal of medicinal chemistry.

Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing the cfr Methyltransferase Gene or Ribosomal Mutations

J. Stein, M. Hilgers, Gracia Morales, 2010, Antimicrobial Agents and Chemotherapy.

Evaluation of the metS and murB Loci for Antibiotic Discovery Using Targeted Antisense RNA Expression Analysis in Bacillus anthracis

R. Haselbeck, M. Hilgers, K. Shaw, 2007, Antimicrobial Agents and Chemotherapy.

Synthesis and biological activity of N-Acylated ornithine analogues of daptomycin.

J. Finn, J. Silverman, I. Parr, 2003, Bioorganic & medicinal chemistry letters.

Tricyclic GyrB/ParE (TriBE) Inhibitors: A New Class of Broad-Spectrum Dual-Targeting Antibacterial Agents

Felice C. Lightstone, Toan B. Nguyen, Sergio E. Wong, 2013, PloS one.

TOTAL SYNTHESIS OF THE HYPOCHOLESTEROLEMIC AGENT (+)‐COMPACTIN

J. Finn, P. Grieco, R. Zelle, 1983 .

Evaluation of WO2012177707 and WO2012097269: Vertex's phosphate prodrugs of gyrase and topoisomerase antibacterial agents

J. Finn, 2013, Expert opinion on therapeutic patents.

A Useful and Conveniently Accessible Chiral Stationary Phase for the Liquid Chromatographic Separation of Enantiomers

J. Finn, B. Hamper, W. H. Pirkle, 1982 .

The identification of quality antibacterial drug discovery targets: a case study with aminoacyl-tRNA synthetases

John Finn, P. Gallant, P. Wendler, 2000 .

Identification of novel inhibitors of methionyl-tRNA synthetase (MetRS) by virtual screening.

Mark Stidham, Mark Hilgers, John Finn, 2008, Bioorganic & medicinal chemistry letters.

SYNTHESIS OF α-HYDROXYCARBONYL COMPOUNDS (ACYLOINS): DIRECT OXIDATION OF ENOLATES USING 2-SULFONYLOXAZIRIDINES

J. Finn, F. A. Davis, L. C. Vishwakarma, 1985 .

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.

Toan B. Nguyen, Sergio E. Wong, J. Nix, 2013, Bioorganic & medicinal chemistry letters.

Rational herbicide design by inhibition of tryptophan biosynthesis.

J. Finn, S. Rodaway, C. Langevine, 1999, Bioorganic & Medicinal Chemistry Letters.