J. P. Petzer

发表

Drug Design and Discovery in Alzheimer’s Disease

Kenneth J. Witt, M. Z. Ahmad, Eric A. Owens, 2014 .

Inhibition of monoamine oxidase by indole and benzofuran derivatives.

J. P. Petzer, L. H. Prins, S. Malan, 2010, European journal of medicinal chemistry.

The Inhibition of Monoamine Oxidase by Esomeprazole

J. P. Petzer, A. Petzer, A. Pienaar, 2013, Drug Research.

The evaluation of 1,4-benzoquinones as inhibitors of human monoamine oxidase.

J. P. Petzer, A. Petzer, S. Mostert, 2017, European journal of medicinal chemistry.

Monoamine oxidase B inhibition and neuroprotection

C. J. Van der Schyf, Jiang-Fan Chen, M. Schwarzschild, 2003, Neurology.

Inhibition of monoamine oxidase by 8-phenoxymethylcaffeine derivatives.

A. J. Swanepoel, J. P. Petzer, J. Bergh, 2012, Bioorganic & medicinal chemistry.

Selected C7-substituted chromone derivatives as monoamine oxidase inhibitors.

L. Legoabe, J. P. Petzer, A. Petzer, 2012, Bioorganic chemistry.

Structure-activity relationships for the inhibition of monoamine oxidase by 8-( 2-phenoxyethoxy ) caffeine analogues

J. P. Petzer, J. Bergh, B. Strydom, 2013 .

Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues.

J. P. Petzer, J. Bergh, C. I. Manley-King, 2011, Bioorganic & medicinal chemistry.

Monoamine oxidase inhibition by selected anilide derivatives.

L. Legoabe, J. P. Petzer, J. Bergh, 2011, European journal of medicinal chemistry.

Inhibition of monoamine oxidase by C5-substituted phthalimide analogues.

J. P. Petzer, J. Bergh, C. I. Manley-King, 2011, Bioorganic & medicinal chemistry.

Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues.

J. P. Petzer, S. Malan, N. Castagnoli, 2010, Bioorganic & medicinal chemistry.

Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides.

J. P. Petzer, N. Castagnoli, G. Terre’Blanche, 2009, Bioorganic & medicinal chemistry.

Structure-activity relationships in the inhibition of monoamine oxidase B by 1-methyl-3-phenylpyrroles.

J. P. Petzer, S. Malan, N. Castagnoli, 2008, Bioorganic & medicinal chemistry.

Methylene blue analogues: In vitro antimicrobial minimum inhibitory concentrations and in silico pharmacophore modelling.

J. Bezuidenhout, J. P. Petzer, A. Petzer, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The adenosine receptor affinities and monoamine oxidase B inhibitory properties of sulfanylphthalimide analogues.

J. P. Petzer, G. Terre’Blanche, M. M. van der Walt, 2015, Bioorganic chemistry.

Dual inhibition of monoamine oxidase B and antagonism of the adenosine A(2A) receptor by (E,E)-8-(4-phenylbutadien-1-yl)caffeine analogues.

J. P. Petzer, S. Malan, N. Castagnoli, 2008, Bioorganic & medicinal chemistry.

Discovery of 1,3-diethyl-7-methyl-8-(phenoxymethyl)-xanthine derivatives as novel adenosine A1 and A2A receptor antagonists.

J. P. Petzer, G. Terre’Blanche, M. M. van der Walt, 2016, Bioorganic & medicinal chemistry letters.

Development of novel techniques to extract phenolic compounds from Romanian cultivars of Prunus domestica L. and their biological properties.

S. Carradori, G. Zengin, M. Locatelli, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Evaluation of Selected Natural Compounds as Dual Inhibitors of Catechol- O-Methyltransferase and Monoamine Oxidase.

J. P. Petzer, A. Petzer, Idalet Engelbrecht, 2019, Central nervous system agents in medicinal chemistry.

An evaluation of synthetic indole derivatives as inhibitors of monoamine oxidase.

J. P. Petzer, K. Y. Suponitsky, I. Abramov, 2016, Bioorganic & medicinal chemistry letters.

The Design and Evaluation of an l-Dopa–Lazabemide Prodrug for the Treatment of Parkinson’s Disease

J. P. Petzer, F. Viljoen, A. Petzer, 2017, Molecules.

The synthesis and evaluation of sesamol and benzodioxane derivatives as inhibitors of monoamine oxidase.

J. P. Petzer, A. Petzer, Idalet Engelbrecht, 2015, Bioorganic & medicinal chemistry letters.

Evaluation of nitrocatechol chalcone and pyrazoline derivatives as inhibitors of catechol-O-methyltransferase and monoamine oxidase.

J. P. Petzer, A. Petzer, Rialette Hitge, 2020, Bioorganic & medicinal chemistry letters.

The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase.

L. Legoabe, J. P. Petzer, A. Petzer, 2022, Bioorganic & medicinal chemistry letters.

The Synthesis and Evaluation of C7‐Substituted α‐Tetralone Derivatives as Inhibitors of Monoamine Oxidase

L. Legoabe, J. P. Petzer, A. Petzer, 2015, Chemical biology & drug design.

Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B.

J. P. Petzer, H. Fourie, N. Castagnoli, 2010, Bioorganic & medicinal chemistry.

Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B.

J. P. Petzer, N. Castagnoli, G. Terre’Blanche, 2008, Bioorganic & medicinal chemistry.

Neurotoxicity studies with the monoamine oxidase B substrate 1-methyl-3-phenyl-3-pyrroline.

J. P. Petzer, S. Malan, K. Castagnoli, 2007, Life sciences.

The inhibition of monoamine oxidase by phenformin and pentamidine.

M. Barkhuizen, J. P. Petzer, A. Petzer, 2013, Drug research.

Metabolic defects caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and by HPTP (the tetrahydropyridinyl analog of haloperidol), in rats.

C. J. Van der Schyf, J. P. Petzer, N. Castagnoli, 2000, Life sciences.

Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor

M. Dimanche-Boitrel, M. Rousselot, B. Baratte, 2021, Molecules.

Phase 2 enzyme induction by the major metabolite of oltipraz.

M. Kwak, T. Kensler, J. P. Petzer, 2003, Chemical research in toxicology.

derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity

Paola, S. Carradori, G. Zengin, 2019 .

Optimization of pyrrolo[3,4‐f]indole‐5,7‐dione and indole‐5,6‐dicarbonitrile derivatives as inhibitors of monoamine oxidase

J. P. Petzer, I. Abramov, A. Petzer, 2019, Drug development research.

Monoamine Oxidase Inhibition by Kavalactones from Kava (Piper Methysticum)

J. P. Petzer, A. Petzer, S. van Dyk, 2019, Planta Medica.

An investigation of the monoamine oxidase inhibition properties of pyrrolo[3,4‐f]indole‐5,7‐dione and indole‐5,6‐dicarbonitrile derivatives

A. Veselovsky, J. P. Petzer, I. Abramov, 2018, Drug development research.

Isatoic anhydrides as novel inhibitors of monoamine oxidase.

J. P. Petzer, A. Petzer, Rialette Hitge, 2022, Bioorganic & medicinal chemistry.

derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis

Zengin, S. Carradori, D. Secci, 2019 .

Inhibition of monoamine oxidase by phthalide analogues.

J. P. Petzer, J. Bergh, B. Strydom, 2013, Bioorganic & medicinal chemistry letters.

Sulfanylphthalonitrile analogues as selective and potent inhibitors of monoamine oxidase B.

J. P. Petzer, G. Terre’Blanche, M. M. van der Walt, 2012, Bioorganic & medicinal chemistry letters.

8-Aryl- and alkyloxycaffeine analogues as inhibitors of monoamine oxidase.

J. P. Petzer, J. Bergh, B. Strydom, 2011, European journal of medicinal chemistry.

The interactions of azure B, a metabolite of methylene blue, with acetylcholinesterase and butyrylcholinesterase.

B. Harvey, J. P. Petzer, A. Petzer, 2014, Toxicology and applied pharmacology.

Coumarin derivatives as inhibitors of d-amino acid oxidase and monoamine oxidase.

J. P. Petzer, A. Petzer, E. Bester, 2022, Bioorganic chemistry.

The inhibition of monoamine oxidase by harmine derivatives

J. P. Petzer, A. Petzer, Theo Myburg, 2022, Results in Chemistry.

Inhibition of monoamine oxidase B by selec- tive 7-substituted coumarin derivatives

J. P. Petzer, S. Malan, J. Bergh, 2008 .

Rational approaches towards reversible inhibition of type B monoamine oxidase. Design and evaluation of a novel 5H-Indeno[1,2-c]pyridazin-5-one derivative.

C. J. Van der Schyf, J. Wouters, F. Ooms, 2003, Bioorganic & medicinal chemistry letters.

New β-arylchalcogeno amines with procognitive properties targeting Carbonic Anhydrases and Monoamine Oxidases.

S. Carradori, C. Supuran, D. Vullo, 2022, European journal of medicinal chemistry.

Synthesis and evaluation of 2-substituted 4(3H)-quinazolinone thioether derivatives as monoamine oxidase inhibitors.

L. Legoabe, J. P. Petzer, A. Petzer, 2018, Bioorganic & medicinal chemistry.

Novel monoamine oxidase inhibitors: a patent review (2012 – 2014)

S. Carradori, J. P. Petzer, J. Petzer, 2015, Expert opinion on therapeutic patents.

Design, synthesis and biochemical evaluation of novel multi-target inhibitors as potential anti-Parkinson agents.

C. De Monte, S. Carradori, G. Zengin, 2018, European journal of medicinal chemistry.

Inhibition of monoamine oxidase B by selective adenosine A2A receptor antagonists.

C. J. Van der Schyf, M. Schwarzschild, J. P. Petzer, 2003, Bioorganic & medicinal chemistry.

An updated patent review on monoamine oxidase (MAO) inhibitors

S. Carradori, Cristina Campestre, J. P. Petzer, 2022, Expert opinion on therapeutic patents.

Interactions of dye compounds that are structurally related to methylene blue with acetylcholinesterase and butyrylcholinesterase

J. P. Petzer, A. Petzer, Stephanus J. Cloete, 2020, Chemical Biology & Drug Design.

Synthesis and in vitro antiprotozoal evaluation of novel metronidazole-Schiff base hybrids.

M. Isaacs, K. Land, Richard M. Beteck, 2022, Archiv der Pharmazie.

Coumarin-Based Dual Inhibitors of Human Carbonic Anhydrases and Monoamine Oxidases Featuring Amino Acyl and (Pseudo)-Dipeptidyl Appendages: In Vitro and Computational Studies

S. Carradori, C. Supuran, Mariangela Agamennone, 2022, Molecules.

α-Tetralone derivatives as inhibitors of monoamine oxidase.

L. Legoabe, J. P. Petzer, A. Petzer, 2014, Bioorganic & medicinal chemistry letters.

Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives.

J. P. Petzer, A. Petzer, Letitia Meiring, 2013, Bioorganic & medicinal chemistry letters.

Inhibition of monoamine oxidase by (E)-styrylisatin analogues.

D. Edmondson, J. P. Petzer, S. Malan, 2009, Bioorganic & medicinal chemistry letters.

Inhibition of monoamine oxidase B by analogues of the adenosine A2A receptor antagonist (E)-8-(3-chlorostyryl)caffeine (CSC).

J. P. Petzer, S. Malan, N. Castagnoli, 2006, Bioorganic & Medicinal Chemistry.

Investigation of pyrazolo[1,5-a]quinoxalin-4-ones as novel monoamine oxidase inhibitors.

J. P. Petzer, A. Shetnev, A. Petzer, 2020, Bioorganic chemistry.

Inhibition of monoamine oxidase by indole-5,6-dicarbonitrile derivatives.

J. P. Petzer, I. Abramov, A. Petzer, 2015, Bioorganic & medicinal chemistry letters.

Monoamine oxidase inhibitory activities of heterocyclic chalcones.

J. P. Petzer, A. Petzer, A. Lourens, 2015, Bioorganic & medicinal chemistry letters.

Monoamine oxidase inhibition by C4-substituted phthalonitriles.

J. P. Petzer, J. Bergh, C. I. Manley-King, 2012, Bioorganic chemistry.

Inhibition of monoamine oxidase by 8-[(phenylethyl)sulfanyl]caffeine analogues.

J. P. Petzer, J. Bergh, A. Petzer, 2012, Bioorganic & medicinal chemistry.

Methylene Blue Analogues with Marginal Monoamine Oxidase Inhibition Retain Antidepressant-like Activity.

B. Harvey, J. P. Petzer, A. Petzer, 2018, ACS chemical neuroscience.

Methylene blue and its analogues as antidepressant compounds

B. Harvey, J. P. Petzer, A. Petzer, 2017, Metabolic Brain Disease.

Selected furanochalcones as inhibitors of monoamine oxidase.

J. P. Petzer, J. Bergh, A. Petzer, 2013, Bioorganic & medicinal chemistry letters.

Multifunctional enzyme inhibition for neuroprotection: a focus on MAO, NOS, and AChE inhibitors

B. P. Repsold, J. P. Petzer, J. Joubert, 2014 .

SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs

Y. Sari, F. Alasmari, Raed Shalaby, 2019, Journal of enzyme inhibition and medicinal chemistry.

The inhibition of monoamine oxidase by 2H-1,4-benzothiazin-3(4H)-ones.

J. P. Petzer, A. Petzer, Rialette Hitge, 2022, Bioorganic & medicinal chemistry letters.

Phenothiazine, anthraquinone and related tricyclic derivatives as inhibitors of monoamine oxidase.

J. P. Petzer, A. Petzer, Roslyn Lefin, 2021, Bioorganic & medicinal chemistry.

The evaluation of 1-tetralone and 4-chromanone derivatives as inhibitors of monoamine oxidase

L. Legoabe, J. P. Petzer, A. Petzer, 2020, Molecular diversity.

C6- and C7-Substituted 3,4-dihydro-2(1H)-quinolinones as Inhibitors of Monoamine Oxidase

J. P. Petzer, A. Petzer, Letitia Meiring, 2016, Drug Research.

Evaluation of Natural and Synthetic 1,4‐naphthoquinones as Inhibitors of Monoamine Oxidase

J. P. Petzer, A. Petzer, S. Mostert, 2016, Chemical biology & drug design.

3-Coumaranone derivatives as inhibitors of monoamine oxidase

L. Legoabe, J. P. Petzer, A. Petzer, 2015, Drug design, development and therapy.

Indanones As High‐Potency Reversible Inhibitors of Monoamine Oxidase

J. P. Petzer, A. Petzer, S. Mostert, 2015, ChemMedChem.

Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues.

J. P. Petzer, S. Malan, N. Castagnoli, 2007, Bioorganic & medicinal chemistry.

The monoamine oxidase inhibition properties of C6- and N1-substituted 3-methyl-3,4-dihydroquinazolin-2(1H)-one derivatives

L. Legoabe, J. P. Petzer, A. Petzer, 2019, Molecular Diversity.

The monoamine oxidase inhibition properties of C6-mono- and N3/C6-disubstituted derivatives of 4(3H)-quinazolinone.

L. Legoabe, J. P. Petzer, A. Petzer, 2019, Bioorganic chemistry.

Synthesis and evaluation of chromone derivatives as inhibitors of monoamine oxidase

J. P. Petzer, J. Jordaan, A. Petzer, 2019, Molecular Diversity.

Synthesis and evaluation of chromone derivatives as inhibitors of monoamine oxidase

J. P. Petzer, J. Jordaan, A. Petzer, 2019, Molecular Diversity.

4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis

S. Carradori, G. Zengin, D. Secci, 2019, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and in vitro Evaluation of 2-heteroarylidene-1-tetralone Derivatives as Monoamine Oxidase Inhibitors

L. Legoabe, J. P. Petzer, A. Petzer, 2018, Drug Research.

Methylene blue and its analogues as antidepressant compounds

B. Harvey, J. P. Petzer, A. Petzer, 2017, Metabolic Brain Disease.

2-Heteroarylidene-1-indanone derivatives as inhibitors of monoamine oxidase.

L. Legoabe, J. P. Petzer, A. Petzer, 2016, Bioorganic chemistry.

2-Benzylidene-1-indanone derivatives as inhibitors of monoamine oxidase.

L. Legoabe, J. P. Petzer, A. Petzer, 2016, Bioorganic & medicinal chemistry letters.

Inhibition of monoamine oxidase by benzoxathiolone analogues.

J. P. Petzer, A. Petzer, S. Mostert, 2016, Bioorganic & medicinal chemistry letters.

2-acetylphenol analogs as potent reversible monoamine oxidase inhibitors

L. Legoabe, J. P. Petzer, A. Petzer, 2015, Drug design, development and therapy.

Inhibition of monoamine oxidase by selected phenylalkylcaffeine analogues

J. P. Petzer, J. Bergh, A. Petzer, 2014, The Journal of pharmacy and pharmacology.

The interactions of caffeine with monoamine oxidase.

J. P. Petzer, A. Petzer, A. Pienaar, 2013, Life sciences.

Inhibition of monoamine oxidase by selected C6-substituted chromone derivatives.

L. Legoabe, J. P. Petzer, A. Petzer, 2012, European journal of medicinal chemistry.

Neuroprotection by Caffeine and A2A Adenosine Receptor Inactivation in a Model of Parkinson's Disease

M. Schwarzschild, P. Sonsalla, J. P. Petzer, 2001, The Journal of Neuroscience.

Exploring 4-substituted-2-thiazolylhydrazones from 2-, 3-, and 4-acetylpyridine as selective and reversible hMAO-B inhibitors.

S. Carradori, R. Silvestri, D. Secci, 2013, European journal of medicinal chemistry.

Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases?

S. Carradori, C. Supuran, Mariangela Agamennone, 2022, Molecules.

The Inhibition of Acetylcholinesterase by Dantrolene and Ondansetron

J. P. Petzer, A. Petzer, C. I. N'Da, 2013, Drug Research.