Ying-Hong Ma

发表

Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics

K. Chou, Shu-Qing Wang, Wei-Ren Xu, 2013, Drug design, development and therapy.

Identification of novel PPARα/γ dual agonists by virtual screening, ADMET prediction and molecular dynamics simulations

Shu-Qing Wang, Wei-Ren Xu, Ying-Hong Ma, 2018, Journal of biomolecular structure & dynamics.

Design Novel Dual Agonists for Treating Type-2 Diabetes by Targeting Peroxisome Proliferator-Activated Receptors with Core Hopping Approach

K. Chou, Shu-Qing Wang, Wei-Ren Xu, 2012, PloS one.

Probing the acting mode and advantages of RMC-4550 as an Src-homology 2 domain-containing protein tyrosine phosphatase (SHP2) inhibitor at molecular level through molecular docking and molecular dynamics

Runling Wang, Ying-Hong Ma, Rui-Rui Wang, 2020, Journal of biomolecular structure & dynamics.

Radiolabeling of HER2 specific Affibody(R) molecule with F-18.

D. Kiesewetter, J. Capala, Ying-Hong Ma, 2008, Journal of fluorine chemistry.

Investigating the reason for loss-of-function of Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) caused by Y279C mutation through molecular dynamics simulation

Runling Wang, Ying-Hong Ma, Rui-Rui Wang, 2020, Journal of biomolecular structure & dynamics.

Design, synthesis and docking study of novel tetracyclic oxindole derivatives as α-glucosidase inhibitors.

Hua Sun, Peng Yu, Yongming Zhang, 2015, Bioorganic & medicinal chemistry letters.

Design potential selective inhibitors for human leukocyte common antigen-related (PTP-LAR) with fragment replace approach

Runling Wang, Zhihui Zheng, Xin-Hua Lu, 2019, Journal of biomolecular structure & dynamics.

Synthesis, evaluation, molecular dynamics simulation and targets identification of novel pyrazole-containing imide derivatives

Shu-Qing Wang, Runling Wang, Ying-Hong Ma, 2020, Journal of biomolecular structure & dynamics.

Exploring the effect of inhibitor AKB‐9778 on VE‐PTP by molecular docking and molecular dynamics simulation

Runling Wang, Ying-Hong Ma, Rui-Rui Wang, 2019, Journal of cellular biochemistry.

Identification of novel inhibitor of protein tyrosine phosphatases delta: structure-based pharmacophore modeling, virtual screening, flexible docking, molecular dynamics simulation, and post-molecular dynamics analysis

Runling Wang, Zhihui Zheng, Xin-Hua Lu, 2020, Journal of biomolecular structure & dynamics.

ADME/toxicity prediction and antitumor activity of novel nitrogenous heterocyclic compounds designed by computer targeting of alkylglycerone phosphate synthase

Ping Yang, Yu Zhu, Ying-Hong Ma, 2018, Oncology letters.

Exploring the effect of E76K mutation on SHP2 cause gain‐of‐function activity by a molecular dynamics study

Runling Wang, Ying-Hong Ma, Wei-Ya Li, 2018, Journal of cellular biochemistry.

Mass Spectrometry and Computer Simulation Predict the Interactions of AGPS and HNRNPK in Glioma

Ying-Hong Ma, Zhaoyu Song, Yu Zhu, 2021, BioMed research international.

Exploring the effect of N308D mutation on protein tyrosine phosphatase‐2 cause gain‐of‐function activity by a molecular dynamics study

Ying-Hong Ma, Rui-Rui Wang, Wei-Ya Li, 2018, Journal of cellular biochemistry.

Synthesis, bioactivity, 3D-QSAR studies of novel dibenzofuran derivatives as PTP-MEG2 inhibitors

Runling Wang, Ying-Hong Ma, Xian-Chao Cheng, 2017, Oncotarget.

Identification of potential leukocyte antigen-related protein (PTP-LAR) inhibitors through 3D QSAR pharmacophore-based virtual screening and molecular dynamics simulation

Runling Wang, Zhihui Zheng, Xin-Hua Lu, 2020, Journal of biomolecular structure & dynamics.

Identification of the potential dual inhibitor of protein tyrosine phosphatase sigma and leukocyte common antigen-related phosphatase by virtual screen, molecular dynamic simulations and post-analysis

Runling Wang, Ying-Hong Ma, Liang Zhou, 2019, Journal of biomolecular structure & dynamics.

Design, synthesis, biological evaluation, common feature pharmacophore model and molecular dynamics simulation studies of ethyl 4-(phenoxymethyl)-2-phenylthiazole-5-carboxylate as Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors

Runling Wang, Zhihui Zheng, Huan Zhang, 2020, Journal of biomolecular structure & dynamics.

Design, Synthesis, Biological Activity and Molecular Dynamics Studies of Specific Protein Tyrosine Phosphatase 1B Inhibitors over SHP-2

Xiaobo Li, Shu-Qing Wang, Runling Wang, 2013, International journal of molecular sciences.

Scaffold-based selective SHP2 inhibitors design using core hopping, molecular docking, biological evaluation and molecular simulation.

Runling Wang, Xin-Hua Lu, Ying-Hong Ma, 2020, Bioorganic chemistry.

The Discovery of a Novel and Selective Inhibitor of PTP1B Over TCPTP: 3D QSAR Pharmacophore Modeling, Virtual Screening, Synthesis, and Biological Evaluation

Wei-Ren Xu, De-Xin Kong, Run-Ling Wang, 2014, Chemical biology & drug design.

Mononitration of a Calix[4]arene Methylene Bridge: Synthesis and Preliminary Catalysis Performances of Bridging Chiral p-tert-Butylcalix[4]arenes with a Monoamino Bridge Substituent in a 1,3-Alternate Conformation.

Guangxing Sun, Ying-Hong Ma, Xingao Peng, 2021, The Journal of organic chemistry.

Synthesis, α-glucosidase inhibitory and molecular docking studies of prenylated and geranylated flavones, isoflavones and chalcones.

Hua Sun, Peng Yu, Yongming Zhang, 2015, Bioorganic & medicinal chemistry letters.

Synthesis of 6-hydroxyaurone analogues and evaluation of their α-glucosidase inhibitory and glucose consumption-promoting activity: Development of highly active 5,6-disubstituted derivatives.

Hua Sun, Peng Yu, Yongming Zhang, 2017, Bioorganic & medicinal chemistry letters.

Natural Prenylchalconaringenins and Prenylnaringenins as Antidiabetic Agents: α-Glucosidase and α-Amylase Inhibition and in Vivo Antihyperglycemic and Antihyperlipidemic Effects.

Hua Sun, Peng Yu, Runling Wang, 2017, Journal of agricultural and food chemistry.

Inhibitory activity evaluation and mechanistic studies of tetracyclic oxindole derivatives as α-glucosidase inhibitors.

Hua Sun, Peng Yu, Yang Yang, 2016, European journal of medicinal chemistry.

Exploring the mechanism of C473D mutation on CDC25B causing weak binding affinity with CDK2/CyclinA by molecular dynamics study.

Runling Wang, Ying-Hong Ma, Wei-Ya Li, 2023, Journal of biomolecular structure & dynamics.

Design, synthesis and biological evaluation of pyridine derivatives as selective SHP2 inhibitors.

Runling Wang, Ying-Hong Ma, Rui-Rui Wang, 2020, Bioorganic chemistry.

Exploring the reason for increased activity of SHP2 caused by D61Y mutation through molecular dynamics

Hui Zhou, Ying Ma, Shan Du, 2019, Comput. Biol. Chem..

Exploring the effect of D61G mutation on SHP2 cause gain of function activity by a molecular dynamics study

Wen-Yan Jin, Run-Ling Wang, Wen-Shan Liu, 2018, Journal of biomolecular structure & dynamics.

Design of specific inhibitors of the protein tyrosine phosphatase SHP-2 by virtual screening and core hopping method

Shu-Qing Wang, Wei-Ren Xu, Runling Wang, 2014 .

Structure-based discovery of a specific SHP2 inhibitor with enhanced blood-brain barrier penetration from PubChem database.

Runling Wang, Xin-Hua Lu, Ying-Hong Ma, 2022, Bioorganic chemistry.

The design of novel inhibitors for treating cancer by targeting CDC25B through disruption of CDC25B-CDK2/Cyclin A interaction using computational approaches

Xiu-Bo Chen, Run-Ling Wang, Wei-Li Dong, 2017, Oncotarget.

Design, synthesis, biological evaluation and molecular dynamics simulation studies of (R)-5-methylthiazolidin-4-One derivatives as megakaryocyte protein tyrosine phosphatase 2 (PTP-MEG2) inhibitors for the treatment of type 2 diabetes

Runling Wang, Ying-Hong Ma, Jingwei Wu, 2019, Journal of biomolecular structure & dynamics.

The design of a homocysteine fluorescent probe based on Rhodamine B and its responsiveness in the serum of cerebral infarction patients.

Yu Zhu, Ying-Hong Ma, Xu Li, 2019, Experimental and therapeutic medicine.

Structure based design of selective SHP2 inhibitors by De novo design, synthesis and biological evaluation

Liang Zhou, Wen-Yan Jin, Wei-Ya Li, 2019, Journal of Computer-Aided Molecular Design.

Natural 8-C-ascorbyl-(-)-epigallocatechin as antidiabetic agent: α-glucosidase and PTP-1B signaling pathway dual regulators.

Hua Sun, Ying-Hong Ma, Yinan Zhang, 2022, Fitoterapia.

Scaffold-based novel SHP2 allosteric inhibitors design using Receptor-Ligand pharmacophore model, virtual screening and molecular dynamics

Ying Ma, Hong-Lian Li, Wen-Yan Jin, 2018, Comput. Biol. Chem..

3D QSAR Pharmacophore Based Virtual Screening for Identification of Potential Inhibitors for CDC25B

Xiubo Chen, Hui Zhou, Ying Ma, 2018, Comput. Biol. Chem..

Design, synthesis, biological evaluation and molecular dynamics of LAR inhibitors

Run-Ling Wang, Ying-Zhan Sun, Jing-Wei Wu, 2021, Comput. Biol. Chem..

Exploring the mechanism of the potent allosteric inhibitor compound2 on SHP2 WT and SHP2F285S by molecular dynamics study.

Runling Wang, Xin-Hua Lu, Ying-Hong Ma, 2020, Journal of molecular graphics & modelling.

Exploring the dynamic mechanism of allosteric drug SHP099 inhibiting SHP2E69K

Runling Wang, Xin-Hua Lu, Ying-Hong Ma, 2021, Molecular Diversity.

Exploring the dynamic mechanism of allosteric drug SHP099 inhibiting SHP2E69K

Runling Wang, Xin-Hua Lu, Ying-Hong Ma, 2021, Molecular Diversity.

Setmelanotide optimization through fragment-growing, molecular docking in-silico method targeting MC4 receptor

Yan Zhang, Ying-Hong Ma, Shuqing Wang, 2023, Journal of biomolecular structure & dynamics.

Exploring the effect of aplidin on low molecular weight protein tyrosine phosphatase by molecular docking and molecular dynamic simulation study

Run-Ling Wang, Ying Ma, Xin-Hua Lu, 2019, Comput. Biol. Chem..

Molecular dynamics study of CDC25BR492L mutant causing the activity decrease of CDC25B.

Runling Wang, Ying-Hong Ma, Wen-yu Yang, 2021, Journal of molecular graphics & modelling.