Jufang Shan

发表

Identification of a specific inhibitor of the dishevelled PDZ domain.

Jie J. Zheng, Junmei Wang, Jufang Shan, 2005, Biochemistry.

Discovery and Characterization of a Small Molecule Inhibitor of the PDZ Domain of Dishevelled*

Jie J. Zheng, D. Grandy, R. Lang, 2009, The Journal of Biological Chemistry.

Functional insight into Maelstrom in the germline piRNA pathway: a unique domain homologous to the DnaQ-H 3'–5' exonuclease, its lineage-specific expansion/loss and evolutionarily active site switch

X. Xia, Dapeng Zhang, V. Trudeau, 2008, Biology Direct.

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base

George Khelashvili, Kevin C. Dorff, Jufang Shan, 2010, Bioinform..

Virtual ligand screening combined with NMR to identify Dvl PDZ domain inhibitors targeting the Wnt signaling.

Jie J. Zheng, Jufang Shan, 2012, Methods in molecular biology.

Probing the structural determinants for the function of intracellular loop 2 in structurally cognate G-protein-coupled receptors.

H. Weinstein, E. Mehler, Jufang Shan, 2010, Biochemistry.

Structural Insight into the Mechanisms of Wnt Signaling Antagonism by Dkk*

Jie J. Zheng, Dianqing Wu, Xiaofeng Li, 2008, Journal of Biological Chemistry.

A Functional Selectivity Mechanism at the Serotonin-2A GPCR Involves Ligand-Dependent Conformations of Intracellular Loop 2

George Khelashvili, Jufang Shan, Harel Weinstein, 2014, Journal of the American Chemical Society.

Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium

F. Maxfield, E. Rodriguez-Boulan, A. P. Perez Bay, 2014, Proceedings of the National Academy of Sciences.

Quantitative modeling of membrane deformations by multihelical membrane proteins: application to G-protein coupled receptors.

George Khelashvili, Jufang Shan, Harel Weinstein, 2011, Biophysical journal.

An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth.

K. Uematsu, R. Guy, G. Neale, 2007, Cancer research.

Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism

Jie J. Zheng, G. Shulman, Dianqing Wu, 2012, Proceedings of the National Academy of Sciences.

Synthesis of Potent Dishevelled PDZ Domain Inhibitors Guided by Virtual Screening and NMR Studies

Jie J. Zheng, Jufang Shan, Xinxin Zhang, 2012, Chemical biology & drug design.

Ligand-Dependent Conformations and Dynamics of the Serotonin 5-HT2A Receptor Determine Its Activation and Membrane-Driven Oligomerization Properties

George Khelashvili, Jufang Shan, Harel Weinstein, 2012, PLoS Comput. Biol..

Optimizing Dvl PDZ domain inhibitor by exploring chemical space

Jufang Shan, Jie J. Zheng, Jufang Shan, 2009, J. Comput. Aided Mol. Des..

The Substrate-Driven Transition to an Inward-Facing Conformation in the Functional Mechanism of the Dopamine Transporter

H. Weinstein, Lei Shi, J. Javitch, 2011, PloS one.

Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism

Jie J. Zheng, G. Shulman, Dianqing Wu, 2012, Proceedings of the National Academy of Sciences of the United States of America.

Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation

H. Weinstein, Lei Shi, J. Javitch, 2014, Neurochemistry International.