E. Sudbeck

发表

Rational Design and Synthesis of a Novel Anti-leukemic Agent Targeting Bruton′s Tyrosine Kinase (BTK), LFM-A13 [α-Cyano-β-Hydroxy-β-Methyl-N-(2,5-Dibromophenyl)Propenamide]*

F. Uckun, S. Mahajan, Y. Zheng, 1999, The Journal of Biological Chemistry.

Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury.

Y. Satoh, B. Bennett, D. Giegel, 2012, Bioorganic & medicinal chemistry letters.

Anti-HIV activity of aromatic and heterocyclic thiazolyl thiourea compounds.

F. Uckun, E. Sudbeck, T. Venkatachalam, 2001, Bioorganic & medicinal chemistry letters.

Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus.

F. Uckun, E. Sudbeck, T. Venkatachalam, 1999, Bioorganic & medicinal chemistry letters.

Structure-based design of N-[2-(1-piperidinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea and N-[2-(1-piperazinylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea as potent non-nucleoside inhibitors of HIV-1 reverse transcriptase.

F. Uckun, E. Sudbeck, T. Venkatachalam, 1998, Bioorganic & medicinal chemistry letters.

5-Alkyl-2-[(methylthiomethyl)thio]-6-(benzyl)-pyrimidin-4-(1H)-ones as potent non-nucleoside reverse transcriptase inhibitors of S-DABO series.

F. Uckun, E. Sudbeck, T. Venkatachalam, 1998, Bioorganic & medicinal chemistry letters.

Piperidinylethyl, Phenoxyethyl and Fluoroethyl Bromopyridyl Thiourea Compounds with Potent Anti-HIV Activity

F. Uckun, E. Sudbeck, C. Mao, 2000, Antiviral chemistry & chemotherapy.

CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation.

F. Uckun, E. Sudbeck, C. Mao, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Recent advances in JAK3 kinase inhibitors.

F. Uckun, E. Sudbeck, 1999, IDrugs : the investigational drugs journal.

Potent inhibition of influenza sialidase by a benzoic acid containing a 2-pyrrolidinone substituent.

G. Air, M. Luo, D. A. Walsh, 1999, Journal of medicinal chemistry.

Antioxidant function of phenethyl-5-bromo-pyridyl thiourea compounds with potent anti-HIV activity.

F. Uckun, E. Sudbeck, T. Venkatachalam, 2000, Bioorganic & medicinal chemistry letters.

Structure-based design of specific inhibitors of Janus kinase 3 as apoptosis-inducing antileukemic agents.

X. P. Liu, F. Uckun, S. Ghosh, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Synthesis, X-ray structure, and anti-leukemic activity of oxovanadium(IV) complexes.

F. Uckun, E. Sudbeck, R. Narla, 2000, Journal of inorganic biochemistry.

Stereochemistry of halopyridyl and thiazolyl thiourea compounds is a major determinant of their potency as nonnucleoside inhibitors of HIV-1 reverse transcriptase.

F. Uckun, E. Sudbeck, T. Venkatachalam, 2000, Bioorganic & medicinal chemistry letters.

Structural influence on the solid state intermolecular hydrogen bonding of substituted thioureas

F. Uckun, E. Sudbeck, T. Venkatachalam, 2005 .

Regiospecific synthesis, X-ray crystal structure and biological activities of 5-bromothiophenethyl thioureas

F. Uckun, E. Sudbeck, T. Venkatachalam, 2001 .

Structure-based drug design of non-nucleoside inhibitors for wild-type and drug-resistant HIV reverse transcriptase.

F. Uckun, E. Sudbeck, T. Venkatachalam, 2000, Biochemical pharmacology.

Dye solubilization in polyelectrolyte—micelle complexes

J. Skelton, P. Dubin, E. Sudbeck, 1991 .

Complexes of Lysine, Histidine, and Arginine with Sulfonated Azo Dyes: Model Systems for Understanding the Biomolecular Recognition of Glycosaminoglycans by Proteins

T. I. Richardson, E. Sudbeck, W. B. Gleason, 1996 .

Rational design and synthesis of phenethyl-5-bromopyridyl thiourea derivatives as potent non-nucleoside inhibitors of HIV reverse transcriptase

F. Uckun, E. Sudbeck, T. Venkatachalam, 1998 .

Structural influence on the anisotropic intermolecular hydrogen bonding in solid state of substituted thioureas: evidence by X-ray crystal structure

F. Uckun, E. Sudbeck, T. Venkatachalam, 2004 .

Structure-Based Design of Non-Nucleoside Reverse Transcriptase Inhibitors of Drug-Resistant Human Immunodeficiency Virus

F. Uckun, E. Sudbeck, C. Mao, 1999, Antiviral chemistry & chemotherapy.

Structure-Based Design of Novel Dihydroalkoxybenzyloxopyrimidine Derivatives as Potent Nonnucleoside Inhibitors of the Human Immunodeficiency Virus Reverse Transcriptase

Rakesh Vig, Fatih M. Uckun, F. Uckun, 1998, Antimicrobial Agents and Chemotherapy.

Structure-based design of novel anticancer agents.

X. P. Liu, F. Uckun, A. Vassilev, 2001, Current cancer drug targets.

SPIKET and COBRA compounds as novel tubulin modulators with potent anticancer activity.

F. Uckun, A. Vassilev, E. Sudbeck, 2000, Current opinion in investigational drugs.

Rational design and synthesis of phenethyl-5-bromopyridyl thiourea derivatives as potent non-nucleoside inhibitors of HIV reserve transcriptase.

F. Uckun, E. Sudbeck, T. Venkatachalam, 1998, Bioorganic & medicinal chemistry.

Tyrosine kinase inhibitors against EGF receptor-positive malignancies.

X. P. Liu, F. Uckun, Y. Zheng, 2001, Methods in molecular biology.

An inhibitor of Janus kinase 3:4-(4-hydroxyphenylamino)-6, 7-dimethoxyquinazolin-1-ium chloride methanol solvate.

X. P. Liu, F. Uckun, E. Sudbeck, 2000, Acta crystallographica. Section C, Crystal structure communications.

Crystal structures and hydrogen bond analysis of three arenesulfonate salts ofl-alanine, glycine, andl-serine

E. Sudbeck, W. B. Gleason, M. C. Etter, 1995 .

Hydrophobic benzoic acids as inhibitors of influenza neuraminidase.

G. Air, M. Luo, D. A. Walsh, 1999, Bioorganic & medicinal chemistry.

Guanidinobenzoic acid inhibitors of influenza virus neuraminidase.

W G Laver, G. Air, M. Luo, 1997, Journal of molecular biology.

Inhibitor of HIV-1 reverse transcriptase: N'-(5-bromo-2-pyridyl)-N-[2-(2,5-dimethoxyphenyl)ethyl]thiourea.

F. Uckun, E. Sudbeck, T. Venkatachalam, 1999, Acta crystallographica. Section C, Crystal structure communications.

Structure-based design of potent inhibitors of EGF-receptor tyrosine kinase as anti-cancer agents.

X. P. Liu, F. Uckun, E. Sudbeck, 1999, Anti-cancer drug design.