N. Terrett

发表

Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5.

Hualiang Jiang, Yechun Xu, M. Zheng, 2012, Journal of medicinal chemistry.

The exploration of macrocycles for drug discovery — an underexploited structural class

Stephen P. Hale, E. Driggers, S. Hale, 2008, Nature Reviews Drug Discovery.

Methods for the synthesis of macrocycle libraries for drug discovery.

N. Terrett, Nicholas K. Terrett, 2010, Drug discovery today. Technologies.

The discovery of macrocyclic XIAP antagonists from a DNA-programmed chemistry library, and their optimization to give lead compounds with in vivo antitumor activity.

Shana L. Posy, J. Fargnoli, R. Talbott, 2015, Journal of medicinal chemistry.

COMBINATORIAL SYNTHESIS : THE DESIGN OF COMPOUND LIBRARIES AND THEIR APPLICATION TO DRUG DISCOVERY

M. J. Gardner, John Steele, David W. Gordon, 1995 .

Combinatorial Chemistry Online Volume 16, Issue 7, July 2014

N. Terrett, 2013 .

Combinatorial Chemistry Online Volume 17, Issue 4, April 2015

N. Terrett, 2015 .

Combinatorial Chemistry Online Volume 17, Issue 8, August 2015

N. Terrett, 2015 .

The importance of synthetic chemistry in the pharmaceutical industry

P. Coleman, J. Alvarez, M. Truppo, 2019, Science.

UK-69,578, a novel inhibitor of EC 3.4.24.11 which increases endogenous ANF levels and is natriuretic and diuretic.

K. James, M. Wythes, N. Terrett, 1989, Biochemical and biophysical research communications.

The Discovery of Macrocyclic IAP Inhibitors for the Treatment of Cancer

N. Terrett, 2017 .

Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer.

Shana L. Posy, J. Fargnoli, R. Talbott, 2015, ACS medicinal chemistry letters.

The selectivity and potency of the new PDE5 inhibitor TPN729MA.

Qiaojun He, Bo Yang, Xiangrui Jiang, 2013, The journal of sexual medicine.

Combinatorial chemistry online volume 14, issue 9, September 2012

N. Terrett, 2012 .

Radical cyclisations of dienes and enynes using phosphorus- and sulfur-centred radicals

N. Terrett, N. Simpkins, J. Brumwell, 1994 .

Cyclisation of dienes and enynes using phosphorus-centred radicals

N. Terrett, N. Simpkins, J. Brumwell, 1993 .

Cyclisation of carbinyl radicals onto imines and hydrazones

N. Terrett, W. Bowman, P. T. Stephenson, 1994 .

Sildenafil (VIAGRATM), a potent and selective inhibitor of type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction

Andrew Simon Bell, N. Terrett, A. Bell, 1996 .

Combinatorial Chemistry Online

N. Terrett, 2008, Combinatorial Chemistry.

The stereochemistry of some SE2′ reactions of allyl- and allenylsilanes☆

I. Fleming, N. Terrett, 1983 .

Stereocontrol in organic synthesis using silicon-containing compounds. A synthesis of (±)-dihydronepetalactone using the SE2′ reaction of an allylsilane

I. Fleming, N. Terrett, 1998 .

Stereospecific allylsilane reactions: a total synthesis of dihydronepetalactone

I. Fleming, N. Terrett, 1985 .

Stereospecific syntheses and reactions of allyl- and allenyl-silanes

I. Fleming, N. Terrett, 1984 .

Stereospecificity in the synthesis of allylsilanes from tertiary allylic acetates

I. Fleming, N. Terrett, 1984 .

Combinatorial Chemistry Online Volume 13 , Issue 10 , October 2011

N. Terrett, 2011 .

Combinatorial Chemistry Online: Volume 14, Issue 2, February 2012

N. Terrett, 2011 .

Combinatorial Chemistry Online Volume 16, Issue 1, January 2014

N. Terrett, 2014 .

Synthesis of spiroethers using radical cyclisations

N. Terrett, N. Simpkins, D. Middleton, 1990 .

Facile synthesis of functionalised spiroethers via radical cyclisations

N. Terrett, N. Simpkins, D. Middleton, 1988 .

Combinatorial Synthesis ‐ The Design of Compound Libraries and Their Application to Drug Discovery

M. J. Gardner, John Steele, David W. Gordon, 1995 .

RADICAL CYCLISATIONS OF IMINES AND HYDRAZONES

N. Terrett, W. Bowman, P. T. Stephenson, 1995 .

Some uses of silicon compounds in organic synthesis

I. Fleming, N. Terrett, 1978 .

Stereocontrol in Organic Synthesis Using Silicon‐Containing Compounds. A Synthesis of (.+‐.)‐Dihydronepetalactone Using the SE2′ Reaction of an Allylsilane.

I. Fleming, N. Terrett, 1998 .

Combinatorial Chemistry Online Volume 18, Issue 6, June 2016

N. Terrett, 2016 .

Parallel-compound synthesis: methodology for accelerating drug discovery.

N K Terrett, N. Terrett, C N Selway, 1996, Bioorganic & medicinal chemistry.

Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors.

Jian Ding, Jing-kang Shen, Zhen Wang, 2013, Bioorganic & medicinal chemistry.

DNA-encoded chemical libraries of macrocycles.

S. Hale, N. Terrett, W. Connors, 2015, Current opinion in chemical biology.

Applications of combinatorial chemistry to drug design and development.

P J Edwards, M Gardner, W Klute, 1999, Current opinion in drug discovery & development.

Comparison of algorithms for dissimilarity-based compound selection.

P Willett, M Snarey, N K Terrett, 1997, Journal of molecular graphics & modelling.

The application of non-combinatorial chemistry to lead discovery.

F. Pullen, N. Terrett, M. Gardner, 2001, Drug discovery today.

Drug Discovery by Combinatorial Chemistry—the Development of a Novel Method for the Rapid Synthesis of Single Compounds

M. J. Gardner, John Steele, David W. Gordon, 1997 .

The combinatorial synthesis of a 30,752-compound library: discovery of SAR around the endothelin antagonist, FR-139,317

David W. Gordon, D. Bojanic, D. Gordon, 1995 .

Drugs in middle space

N. Terrett, 2013 .

WITHDRAWN: Design, synthesis and biological evaluation of 3-substituted-4-anilinequinoline as EGFR tyrosine kinase inhibitors.

Jian Ding, Jingshan Shen, Jianfeng Li, 2012, Bioorganic & medicinal chemistry letters.

Radical cyclisation of dienes and enynes using TolSO2SePh

N. Terrett, N. Simpkins, J. E. Brumwell, 1993 .

Radical Cyclization of Dienes and Enynes Using TolSO2SePh.

N. Terrett, N. Simpkins, J. E. Brumwell, 1993 .

Synthesis of N-protected spiroamines related to natural products using radical cyclisations

N. Terrett, N. Simpkins, D. Middleton, 1989 .

Synthesis of N-Protected Spiroamines Related to Natural Products Using Radical Cyclizations.

N. Terrett, N. Simpkins, D. Middleton, 1990 .

Combinatorial Chemistry Online Volume 13, Issue 9, September 2011

N. Terrett, 2011 .

Combinatorial Chemistry Online Volume 16, Issue 6, June 2014

N. Terrett, 2014 .

Combinatorial Chemistry Online Volume 13, Issue 9, September 2011

N. Terrett, 2011 .