J. T. Huzil

发表

The Roles of β-Tubulin Mutations and Isotype Expression in Acquired Drug Resistance

Lukasz Kurgan, J. Tuszynski, J. T. Huzil, 2007 .

Discovery and characterization of the laulimalide-microtubule binding mode by mass shift perturbation mapping.

David C Schriemer, Jack Tuszynski, Khaled Barakat, 2010, Chemistry & biology.

A computational model for overcoming drug resistance using selective dual-inhibitors for aurora kinase A and its T217D variant.

K. E. Jordan, J. Tuszynski, M. Houghton, 2013, Molecular pharmaceutics.

The Roles of β-Tubulin Mutations and Isotype Expression in Acquired Drug Resistance

Lukasz Kurgan, J. Tuszynski, J. T. Huzil, 2007, Cancer Informatics.

Effect of chemical permeation enhancers on stratum corneum barrier lipid organizational structure and interferon alpha permeability.

M. Foldvari, S. Wettig, J. T. Huzil, 2013, Molecular pharmaceutics.

Tubulin electrostatics and isotype specific drug binding

J. Tuszynski, J. Torin Huzil, T. Luchko, 2008 .

Computer assisted design of second-generation colchicine derivatives

Jonathan Y. Mane, J. Tuszynski, J. T. Huzil, 2010, Interdisciplinary Sciences: Computational Life Sciences.

Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing.

Andreas Antoniou, Lukasz Kurgan, Ke Chen, 2008, Journal of molecular graphics & modelling.

Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: towards non-invasive glaucoma gene therapy.

J. Sivak, M. Foldvari, M. Beazely, 2014, Nanomedicine : nanotechnology, biology, and medicine.

Challenges in neuroprotective nanomedicine development: progress towards noninvasive gene therapy of glaucoma.

M. Foldvari, J. T. Huzil, M. V. Ivanova, 2012, Nanomedicine.

Pharmaceutical characterization of solid and dispersed carbon nanotubes as nanoexcipients

M. J. Loureiro, M. Foldvari, C. Lamprecht, 2012, International journal of nanomedicine.

Conformational analysis of the carboxy-terminal tails of human beta-tubulin isotypes.

J. Tuszynski, M. Stepanova, T. Luchko, 2008, Biophysical journal.

The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos.

J. Tuszynski, T. Luchko, E. Carpenter, 2006, The International journal of developmental biology.

Identification and Characterization of an Intermediate Taxol Binding Site Within Microtubule Nanopores and a Mechanism for Tubulin Isotype Binding Selectivity

Jack A. Tuszynski, Tyler Luchko, Richard F. Luduena, 2009, J. Chem. Inf. Model..

A unique mode of microtubule stabilization induced by peloruside A.

J. Tuszynski, D. Sackett, D. Schriemer, 2008, Journal of molecular biology.

Direct Catalysis of Lysine 48-linked Polyubiquitin Chains by the Ubiquitin-activating Enzyme*

C. Ptak, M. Ellison, J. T. Huzil, 2007, Journal of Biological Chemistry.

Creation of a Pluripotent Ubiquitin-Conjugating Enzyme

C. Ptak, M. Ellison, J. T. Huzil, 2001, Molecular and Cellular Biology.

Free Energy Calculations on the Binding of Colchicine and Its Derivatives with the α/β-Tubulin Isoforms

Jack A. Tuszynski, Mariusz Klobukowski, Jonathan Y. Mane, 2008, J. Chem. Inf. Model..

Non-Covalent Functionalization of Carbon Nanotubes with Surfactants for Pharmaceutical Applications - A Critical Mini-Review

M. Foldvari, C. Lamprecht, J. T. Huzil, 2011 .

Microtubule assembly of isotypically purified tubulin and its mixtures.

J. Tuszynski, M. Jordan, R. Luduena, 2008, Biophysical journal.

Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail.

C. Ptak, S. McKenna, M. Ellison, 2001, Structure.

Electrostatic Contributions to Colchicine Binding within Tubulin Isotypes

J. Tuszynski, K. Barakat, J. T. Huzil, 2009, Electromagnetic biology and medicine.

The Roles of β-Tubulin Mutations and Isotype Expression in Acquired Drug Resistance

Lukasz Kurgan, J. Tuszynski, J. T. Huzil, 2007 .

Comparative modelling of human β tubulin isotypes and implications for drug binding

J. Tuszynski, J. Torin Huzil, R. Luduena, 2006, Nanotechnology.

A unique mode of microtubule stabilization induced by peloruside A.

Gordon W. Slysz, J. Tuszynski, D. Sackett, 2008, Journal of molecular biology.

Interactions of laulimalide, peloruside, and their derivatives with the isoforms of β-tubulin

J. Tuszynski, M. Klobukowski, J. T. Huzil, 2013 .

Homology modeling of tubulin: influence predictions for microtubule’s biophysical properties

J. Tuszynski, E. Carpenter, R. Luduena, 2006, European Biophysics Journal.

Comparative modelling of human β tubulin isotypes and implications for drug binding

J. Tuszynski, R. Luduena, J. T. Huzil, 2006, Nanotechnology.