E. Meyer

发表

Interactions with aromatic rings in chemical and biological recognition.

F. Diederich, R. K. Castellano, E. Meyer, 2003, Angewandte Chemie.

Crystallographic study of inhibitors of tRNA-guanine transglycosylase suggests a new structure-based pharmacophore for virtual screening.

Gerhard Klebe, Klaus Reuter, François Diederich, 2004, Journal of molecular biology.

Synthesis and In Vitro Evaluation of 2-Aminoquinazolin-4(3H)-one-Based Inhibitors for tRNA-Guanine Transglycosylase (TGT)

G. Klebe, F. Diederich, R. Brenk, 2004 .

Advances in Antiplatelet Agents

M. Riederer, E. Meyer, E. Caroff, 2017 .

Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y(12) antagonists for inhibition of platelet aggregation.

M. Riederer, E. Meyer, A. Treiber, 2014, Bioorganic & medicinal chemistry letters.

Interactions with aromatic rings in chemical and biological recognition.

F. Diederich, R. K. Castellano, E. Meyer, 2003, Angewandte Chemie.

Design, Synthesis, and Pharmacological Evaluation of Benzimidazolo-thiazoles as Potent CXCR3 Antagonists with Therapeutic Potential in Autoimmune Diseases: Discovery of ACT-672125.

E. Meyer, S. Froidevaux, M. Keller, 2022, Journal of medicinal chemistry.

Evolution of a total synthesis of (-)-kendomycin exploiting a Petasis-Ferrier rearrangement/ring-closing olefin metathesis strategy.

E. Meyer, Amos B. Smith, E. Mesaros, 2006, Journal of the American Chemical Society.

Total synthesis of (-)-kendomycin exploiting a Petasis-Ferrier rearrangement/ring-closing olefin metathesis synthetic strategy.

E. Meyer, Amos B. Smith, E. Mesaros, 2005, Journal of the American Chemical Society.

4-((R)-2-{[6-((S)-3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel.

D. Renneberg, M. Riederer, E. Meyer, 2015, Journal of medicinal chemistry.

Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies.

M. Martinic, E. Meyer, S. Froidevaux, 2023, Journal of medicinal chemistry.

Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding.

G. Klebe, F. Diederich, R. Brenk, 2007, Journal of molecular biology.

Synthesis, Biological Evaluation, and Crystallographic Studies of Extended Guanine-Based (lin-Benzoguanine) Inhibitors for tRNA-Guanine Transglycosylase (TGT)

G. Klebe, F. Diederich, R. Brenk, 2006 .

De Novo Design, Synthesis, and In Vitro Evaluation of Inhibitors for Prokaryotic tRNA‐Guanine Transglycosylase: A Dramatic Sulfur Effect on Binding Affinity

Gerhard Klebe, François Diederich, Ruth Brenk, 2002, Chembiochem : a European journal of chemical biology.