H. Ikezawa

发表

Mutation in aspartic acid residues modifies catalytic and haemolytic activities of Bacillus cereus sphingomyelinase.

Y. Matsuo, K. Nishikawa, M. Tomita, 1995, The Biochemical journal.

Bacterial Phosphatidylinositol‐Specific Phospholipases C as Membrane‐Attacking Agents and Tools for Research on GPI‐Anchored Proteins

H. Ikezawa, 2005 .

Bacterial PIPLCs-unique properties and usefulness in studies on GPI anchors.

H. Ikezawa, 1991, Cell biology international reports.

An isoelectric focusing study of acid phosphohydrolases in rat liver lysosomes.

H. Ikezawa, T. Nakabayashi, 1978, Journal of biochemistry.

Identification of a new glycosylphosphatidylinositol-anchored 42-kDa protein and its C-terminal peptides from bovine erythrocytes by gas chromatography-, time-of-flight-, and electrospray-ionization-mass spectrometry.

R. Taguchi, M. Takahashi, H. Ikezawa, 1999, Archives of biochemistry and biophysics.

Purification and cDNA cloning of bovine liver 5'-nucleotidase, a GPI-anchored protein, and its expression in COS cells.

K. Suzuki, R. Taguchi, Y. Suzuki, 1993, Journal of biochemistry.

Mutational analysis of the COOH-terminal hydrophobic domain of bovine liver 5'-nucleotidase as a signal for glycosylphosphatidylinositol (GPI) anchor attachment.

H. Tamura, H. Ikezawa, Y. Furukawa, 1994, Biochimica et biophysica acta.

Microheterogeneity in glycosylphosphatidylinositol anchor structures of bovine liver 5'-nucleotidase.

R. Taguchi, H. Ikezawa, T. Fukui, 1994, Biochemistry.

Glycosylphosphatidylinositol (GPI)-anchored proteins.

H. Ikezawa, Hiroh Ikezawa, 2002, Biological & pharmaceutical bulletin.

Phosphatidyl inositol-specific phospholipase C from Clostridium novyi type A.

R. Taguchi, H. Ikezawa, 1978, Archives of biochemistry and biophysics.

[Development from actions of bacterial phospholipases C on eucaryotic plasma membranes to molecular biology of GPI-anchored proteins].

H. Ikezawa, 1999, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[Molecular biology of the GPI-anchored proteins].

H. Ikezawa, 1997, Nihon saikingaku zasshi. Japanese journal of bacteriology.

Release of alkaline phosphodiesterase I from rat kidney plasma membrane produced by the phosphatidylinositol-specific phospholipase C of Bacillus thuringiensis.

H. Ikezawa, T. Nakabayashi, 1984, Cell structure and function.

Novel inhibition mechanism of Bacillus cereus sphingomyelinase by beryllium fluoride.

K. Ikeda, S. Fujii, H. Ikezawa, 2004, Archives of biochemistry and biophysics.

Accepton concentration effect in the selectivity of acyl coenzyme A: U aclglycerylphosphorylcholine acyltransferase system in rat liver.

H. Okuyama, H. Ikezawa, K. Yamada, 1975, The Journal of biological chemistry.

The action of sphingomyelinase from Bacillus cereus on ATP-depleted bovine erythrocyte membranes and different lipid composition of liposomes.

R. Taguchi, M. Tomita, H. Sawada, 1987, Archives of biochemistry and biophysics.

Molecular properties and kinetic studies on sphingomyelinase of Bacillus cereus.

R. Taguchi, M. Tomita, H. Ikezawa, 1982, Biochimica et biophysica acta.

Studies on phospholipase C from Pseudomonas aureofaciens. I. Purification and some properties of phospholipase C.

H. Ikezawa, S. Sonoki, 1975, Biochimica et biophysica acta.

Nucleotide sequence and expression in Escherichia coli of the gene coding for sphingomyelinase of Bacillus cereus.

S. Nakamura, M. Tomita, C. Little, 1988, European journal of biochemistry.

The role of acidic amino-acid residues in catalytic and adsorptive sites of Bacillus cereus sphingomyelinase.

R. Taguchi, M. Tomita, H. Tamura, 1993, Biochimica et biophysica acta.

Binding of salicylhydroxamic acid and several aromatic donor molecules to Arthromyces ramosus peroxidase, investigated by X-ray crystallography, optical difference spectroscopy, NMR relaxation, molecular dynamics, and kinetics.

S. Takahashi, K. Sato, H. Ikezawa, 1999, Biochemistry.

Two hemorrhagic principles derived from Habu snake venom and their difference in zone electrophoretical mobility.

H. Ikezawa, A. Ohsaka, S. Kondo, 1960, Japanese journal of medical science & biology.

Characterization and cloning of an extremely thermostable, Pyrococcus furiosus-type 4Fe ferredoxin from Thermococcus profundus.

Y. Ogawara, H. Ikezawa, F. Yamakura, 2001, Journal of biochemistry.

Activation of sphingomyelinase from Bacillus cereus by Zn2+ hitherto accepted as a strong inhibitor.

K. Ikeda, S. Fujii, H. Ikezawa, 2005, Archives of biochemistry and biophysics.

Chromogenic assay for the activity of sphingomyelinase from Bacillus cereus and its application to the enzymatic hydrolysis of lysophospholipids.

K. Ikeda, S. Fujii, H. Ikezawa, 2004, Biological & pharmaceutical bulletin.

Secondary structure of sphingomyelinase from Bacillus cereus.

R. Taguchi, M. Tomita, A. Yamada, 1990, Journal of biochemistry.

Bacillus cereus strain SE-1: nucleotide sequence of the sphingomyelinase C gene.

C. Little, H. Ikezawa, F. Haugli, 1988, Nucleic acids research.

Delivery of an accessory signal for cell activation by exogenous phosphatidylinositol‐specific phospholipase C

R. Taguchi, T. Yoshida, I. Nakashima, 1992, FEBS letters.

Evidence of synergy between Thy-1 and CD3/TCR complex in signal delivery to murine thymocytes for cell death.

R. Taguchi, T. Yoshida, I. Nakashima, 1991, Journal of immunology.

5'-Nucleotidase in rat liver lysosomal membranes is anchored via glycosyl-phosphatidylinositol.

R. Taguchi, K. Kato, H. Ikezawa, 1989, Cell structure and function.

Inhibition of NGF-induced neurite outgrowth of PC12 cells by Bacillus cereus sphingomyelinase, a bacterial hemolysin.

H. Ikezawa, S. Ohkuma, K. Kinoshita, 1994, Toxicon : official journal of the International Society on Toxinology.

Effect of 22R-hydroxycholesterol on the action of sphingomyelinase from Bacillus cereus toward bovine erythrocytes.

R. Taguchi, M. Tomita, N. Ikekawa, 1992, Toxicon : official journal of the International Society on Toxinology.

Acyltransferase systems involved in phospholipid metabolism in Saccharomyces cerevisiae.

H. Okuyama, H. Ikezawa, K. Yamada, 1977, Archives of biochemistry and biophysics.

[Bacterial PI-specific phospholipases C physiological actions and applications to the studies of GPI-anchored membrane proteins].

H. Ikezawa, 1992, Nihon saikingaku zasshi. Japanese journal of bacteriology.

Effect of antipain on lysosomal peptide-hydrolases from swine liver.

T. Aoyagi, T. Takeuchi, H. Umezawa, 1972, The Journal of antibiotics.

Effect of protease inhibitors of actinomycetes on lysosomal peptide-hydrolases from swine liver.

T. Aoyagi, T. Takeuchi, H. Umezawa, 1971, The Journal of antibiotics.

Peripheral blood cells are predominantly chimeric of affected and normal cells in patients with paroxysmal nocturnal hemoglobinuria: simultaneous investigation on clonality and expression of glycophosphatidylinositol-anchored proteins

R. Taguchi, T. Kinoshita, H. Saito, 1994 .

R. Taguchi, T. Kinoshita, H. Saito, 1994, Blood.

Analysis of PI (phosphatidylinositol)‐anchoring antigens in a patient of paroxysmal nocturnal hemoglobinuria (PNH) reveals deficiency of 1F5 antigen (CD59), a new complement‐regulatory factor

R. Taguchi, I. Nakashima, Yasuhiro Funahashi, 1990, FEBS letters.

Studies on the quantitative method for determination of hemorrhagic activity of Habu snake venom.

H. Ikezawa, R. Murata, S. Kondo, 1960, Japanese journal of medical science & biology.

Effects of phospholipases C on the beta-receptor-adenylate cyclase system of chick erythrocyte membranes.

R. Taguchi, H. Ikezawa, M. Nakajima, 1986, Biochemical pharmacology.

Blood appearance of rat alkaline phosphatase originating from the duodenum in vitro.

I. Koyama, T. Komoda, H. Ikezawa, 1987, Journal of chromatography.

Application of electrospray ionization MS/MS and matrix-assisted laser desorption/ionization-time of flight mass spectrometry to structural analysis of the glycosyl-phosphatidylinositol-anchored protein.

R. Taguchi, H. Ikezawa, N. Hamakawa, 1999, Journal of biochemistry.

Regulation of membrane lipid synthesis in Escherichia coli after shifts in temperature.

H. Okuyama, H. Ikezawa, S. Nojima, 1977, Biochemistry.

Factors affecting the acyl selectivities of acyltransferases in Escherichia coli.

S. Wakil, H. Okuyama, H. Ikezawa, 1976, The Journal of biological chemistry.

Promotion of cytotoxic T-cell generation in mixed leukocyte culture by phosphatidylinositol-specific phospholipase C from Bacillus thuringiensis

R. Taguchi, M. Kato, I. Nakashima, 1995, Infection and immunity.

Partial release of aminopeptidase N from larval midgut cell membranes of the silkworm, Bombyx mori, by phosphatidylinositol-specific phospholipase C.

R. Taguchi, S. Miyajima, K. Yokota, 1992, Comparative biochemistry and physiology. B, Comparative biochemistry.

The kinetic analysis of hemolysis by Clostridium perfringens(Cl.welchii)α-toxin(phospholipase C).

H. Ikezawa, 1963 .

Molecular cloning of a GPI-anchored aminopeptidase N from Bombyx mori midgut: a putative receptor for Bacillus thuringiensis CryIA toxin.

H. Ikezawa, G. Hua, M. Rasilo, 1998, Gene.

Alkaline phosphodiesterase I release from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C. III. The release from tumor cells.

R. Taguchi, H. Ikezawa, Y. Matsuoka, 1993, The International journal of biochemistry.

Alkaline phosphodiesterase I release from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C. I. The release from rat organs.

H. Ikezawa, T. Nakabayashi, 1986, Journal of Biochemistry (Tokyo).

Protein Anchoring to Membrane by Glycosylphosphatidylinositol. Determination of the COOH-Terminal Signal Peptide Sequence and GPI-Attachment Site in Bovine Liver 5′-Nucleotidase

H. Ikezawa, 1993 .

Release of PI-anchoring enzymes and other effects of phosphatidylinositol-specific phospholipase C from Bacillus thuringiensis on TN-368 cells from a moth ovary.

R. Taguchi, A. Hashimoto, M. Himeno, 1989, Toxicon : official journal of the International Society on Toxinology.

Isolation and Characterization of Bovine Erythrocyte Acetylcholinesterase Solubilized by PI-PLC

R. Taguchi, H. Ikezawa, 1988 .

The Physiological Action of Bacterial Phosphatidylinositol-Specific Phospholipase C the Release of Ectoenzymes and Other Effects

H. Ikezawa, 1986 .

Alkaline phosphodiesterase I release from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C. II. The release from brush border membranes of porcine intestine.

H. Ikezawa, T. Nakabayashi, 1986, Toxicon : official journal of the International Society on Toxinology.

Molecular nature of three liver alkaline phosphatases detected by drug administration in vivo: differences between soluble and membranous enzymes.

M. Watanabe, T. Komoda, H. Ikezawa, 1987, Comparative biochemistry and physiology. B, Comparative biochemistry.

Organ specific properties for human urinary alkaline phosphatases.

I. Koyama, T. Komoda, H. Ikezawa, 1988, Clinica chimica acta; international journal of clinical chemistry.

Membrane anchors of alkaline phosphatase and trehalase associated with the plasma membrane of larval midgut epithelial cells of the silkworm, Bombyx mori.

R. Taguchi, S. Miyajima, K. Yokota, 1989, Journal of biochemistry.

The Physiological Actions of Bacterial Phospholipases C on Eucaryotic Cells and their Membranes

R. Taguchi, M. Tomita, H. Ikezawa, 1982 .

Studies on sphingomyelinase of Bacillus cereus: hydrolytic and hemolytic actions on erythrocyte membranes.

R. Taguchi, M. Mori, H. Ikezawa, 1980, Archives of biochemistry and biophysics.

THE ACTIONS OF BACTERIAL PHOSPHOLIPASES C ON PLASMA MEMBRANE

H. Ikezawa, 1980 .

Phospholipase C from Clostridium novyi type A. I.

R. Taguchi, H. Ikezawa, 1975, Biochimica et biophysica acta.

GEL-FILTRATION OF CLOSTRIDIUM PERFRINGENS ALPHA-TOXIN (PHOSPHLIPASE C).

H. Ikezawa, R. Murata, A. Yamamoto, 1964, Journal of biochemistry.

Studies on the hemolytic and hydrolytic actions of phospholipases against mammalian erythrocyte membranes.

R. Taguchi, H. Ikezawa, 1976, Archives of biochemistry and biophysics.

COMPARATIVE KINETICS OF HEMOLYSIS OF MAMMALIAN ERYTHROCYTES BY CLOSTRIDIUM PERFRINGENS ALPHA-TOXIN (PHOSPHOLIPASE C).

H. Ikezawa, R. Murata, 1964, Journal of biochemistry.

Sphingomyelinase of Bacillus Cereusas a Bacterial Hemolysin

R. Taguchi, M. Tomita, H. Ikezawa, 1991 .

Effects of phospholipases C from bacteria on binding of enkephalin to rat brain membranes.

R. Taguchi, H. Ikezawa, M. Nakajima, 1987, Toxicon : official journal of the International Society on Toxinology.

Effects of metal ions on sphingomyelinase activity of Bacillus cereus.

R. Taguchi, M. Tomita, H. Ikezawa, 1986, Archives of biochemistry and biophysics.

Physiological actions of phosphatidylinositol-specific phospholipase C from Bacillus thuringiensis on KB III cells: alkaline phosphatase release and growth inhibition.

S. Ohta, T. Kato, H. Ikezawa, 1985, Toxicon : official journal of the International Society on Toxinology.

[84] Phosphatidylinositol-specific phospholipase C from Bacillus cereus and Bacillus thurinǵiensis

R. Taguchi, H. Ikezawa, 1981 .

Studies on phosphatidylinositol phosphodiesterase (phospholipase C type) of Bacillus cereus. II. In vivo and immunochemical studies of phosphatase-releasing activity.

R. Taguchi, H. Ikezawa, T. Ohyabu, 1978, Archives of biochemistry and biophysics.

Studies on the Mode of Action of Phospholipases on Mammalian Erythrocytes

R. Taguchi, H. Ikezawa, 1976 .

Haemorrhagic activities of habu snake venom, and their relations to lethal toxicity, proteolytic activities and other pathological activities.

H. Ikezawa, A. Ohsaka, S. Kondo, 1960, British journal of experimental pathology.

Mutational analysis of the C-terminal signal peptide of bovine liver 5'-nucleotidase for GPI anchoring: a study on the significance of the hydrophilic spacer region.

H. Ikezawa, Y. Furukawa, K. Tsukamoto, 1997, Biochimica et biophysica acta.

Identification of chiro-inositol and its formation by isomerization of myo-inositol during hydrolysis of glycosylphosphatidylinositol-anchored proteins.

R. Taguchi, Y. Tsutsui, H. Ikezawa, 1997, Archives of biochemistry and biophysics.

[Phosphatidylinositol as a membrane-protein anchor].

H. Ikezawa, 1991, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

Acetylcholinesterase release from mammalian erythrocytes by phosphatidylinositol-specific phospholipase C of Bacillus thuringiensis and characterization of the released enzyme.

K. Suzuki, R. Taguchi, H. Ikezawa, 1984, Journal of biochemistry.

Characterization of aminopeptidase N from the brush border membrane of the larvae midgut of silkworm, Bombyx mori as a zinc enzyme.

R. Taguchi, M. Tomita, S. Miyajima, 1998, Biochimica et biophysica acta.

T cell maturation stage-linked heterogeneity of the glycosylphosphatidylinositol membrane anchor of Thy-1.

R. Taguchi, T. Yoshida, M. Kato, 1992, Immunobiology.

BACTERIAL PIPLCs-UNIQUE PROPERTIES AND USEFULNESS IN STUDIES ON GPI ANCHORS

H. Ikezawa, 1992 .

A distant evolutionary relationship between bacterial sphingomyelinase and mammalian DNase I

Y. Matsuo, K. Nishikawa, H. Ikezawa, 1996, Protein science : a publication of the Protein Society.

His151 and His296 are the acid-base catalytic residues of Bacillus cereus sphingomyelinase in sphingomyelin hydrolysis.

K. Ikeda, S. Fujii, M. Imagawa, 2003, Biological & pharmaceutical bulletin.

Direct evidence of involvement of glycosylphosphatidylinositol‐anchored proteins in the heavy metal‐mediated signal delivery into T lymphocytes

R. Taguchi, K. Isobe, I. Nakashima, 1995, FEBS letters.

Studies on lipid metabolism in Tetrahymena pyriformis: properties of acyltransferase systems.

H. Okuyama, H. Ikezawa, K. Yamada, 1977, Archives of biochemistry and biophysics.

Complete purification of phosphatidylinositol-specific phospholipase C from a strain of Bacillus thuringiensis.

K. Suzuki, R. Taguchi, H. Ikezawa, 1983, Journal of biochemistry.

Glu-53 of Bacillus cereus sphingomyelinase acts as an indispensable ligand of Mg2+ essential for catalytic activity.

M. Imagawa, H. Ikezawa, T. Obama, 2003, Journal of biochemistry.

Studies on sphingomyelinase of Bacillus cereus. I. Purification and properties.

R. Taguchi, M. Mori, H. Ikezawa, 1978, Biochimica et biophysica acta.

Cloning and sequence analysis of the aminopeptidase N isozyme (APN2) from Bombyx mori midgut.

H. Ikezawa, G. Hua, K. Tsukamoto, 1998, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Establishment and characterisation of human carcinoembryonic antigen transgenic mice.

K. Shimokata, I. Nakashima, S. Oikawa, 1991, British Journal of Cancer.

[GPI-anchored proteins].

H. Ikezawa, 1999, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

The study on phosphatidylinositol-specific phospholipase C from Bacillus thuringiensis: synthesis of homogeneous substrates, substrate specificity and other properties.

R. Taguchi, M. Tomita, J. Hirano, 1992, Chemical & pharmaceutical bulletin.

Protein anchoring to membrane by glycosylphosphatidylinositol

H. Ikezawa, 1992 .

Quantitative analysis of the Epstein-Barr virus-inducing properties of short-chain fatty acids present in the culture fluids of oral bacteria

H. Ikezawa, Y. Nakamura, I. Namikawa, 2005, Archives of Virology.

Phospholipase C from Clostridium novyi type A. II. Factors influencing the enzyme activity.

R. Taguchi, H. Ikezawa, 1977, Journal of biochemistry.

Ectoenzyme release from rat liver and kidney by phosphatidylinositol-specific phospholipase C.

R. Taguchi, H. Ikezawa, Y. Asahi, 1985, Journal of biochemistry.

Alkaline phosphodiesterase I release from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C--IV. The release from Cacia porcellus organs.

H. Ikezawa, Y. Matsuoka, T. Nakabayashi, 1994, The International journal of biochemistry.

Adsorption of sphingomyelinase of Bacillus cereus onto erythrocyte membranes.

R. Taguchi, M. Tomita, H. Ikezawa, 1983, Archives of biochemistry and biophysics.

Mg2+ binding and catalytic function of sphingomyelinase from Bacillus cereus.

M. Tomita, K. Ikeda, S. Fujii, 1998, Journal of biochemistry.

Establishment and characterisation of human carcinoembryonic antigen transgenic mice.

K. Shimokata, K. Isobe, I. Nakashima, 1991, British Journal of Cancer.

Solubilization of trehalase from rabbit renal and intestinal brush‐border membranes by a phosphatidylinositol‐specific phospholipase C

R. Taguchi, H. Ikezawa, Y. Nishi, 1986, FEBS letters.

Kinetics of the hydrolysis of monodispersed and micellar phosphatidylcholines catalyzed by a phospholipase C from Bacillus cereus.

K. Ikeda, H. Ikezawa, K. Teshima, 1991, Journal of biochemistry.

Roles of asp126 and asp156 in the enzyme function of sphingomyelinase from Bacillus cereus.

S. Katsumura, M. Tomita, K. Ikeda, 1999, Journal of biochemistry.