O. Patel

发表

Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.

N. K. Williams, J. Rossjohn, A. Wilks, 2009, Journal of molecular biology.

MR1 presents microbial vitamin B metabolites to MAIT cells

Malcolm J. McConville, James McCluskey, Anthony W. Purcell, 2012, Nature.

CD1d-lipid antigen recognition by the γδ TCR

Jamie Rossjohn, T. Beddoe, J. Rossjohn, 2013, Nature Immunology.

The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.

N. K. Williams, J. Rossjohn, A. Wilks, 2007, Journal of molecular biology.

Recognition of CD1d-restricted antigens by natural killer T cells

J. Rossjohn, D. Pellicci, D. Godfrey, 2012, Nature Reviews Immunology.

The kinase activity of the cancer stem cell marker DCLK1 drives gastric cancer progression by reprogramming the stromal tumor landscape

N. Gray, R. Busuttil, A. Boussioutas, 2022, bioRxiv.

Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex*

G. Besra, J. Rossjohn, S. Porcelli, 2012, The Journal of Biological Chemistry.

This information is current as-Galactosylceramide C-α NKT TCR Recognition of CD 1 d-Godfrey and

T. Beddoe, J. McCluskey, D. Pellicci, 2011 .

A molecular basis for NKT cell recognition of CD1d-self-antigen.

P. Marrack, J. McCluskey, J. Rossjohn, 2011, Immunity.

A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells.

G. Besra, J. McCluskey, J. Rossjohn, 2011, Immunity.

A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen–recognition properties

Spencer J. Williams, G. Besra, S. Turner, 2011, Nature Immunology.

NKT TCR Recognition of CD1d-α-C-Galactosylceramide

T. Beddoe, J. McCluskey, J. Rossjohn, 2011, The Journal of Immunology.

T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire.

P. Marrack, J. McCluskey, J. Rossjohn, 2009, Immunity.

Adaptability of the semi‐invariant natural killer T‐cell receptor towards structurally diverse CD1d‐restricted ligands

William C. Florence, J. McCluskey, J. Rossjohn, 2009, The EMBO journal.

Adaptability of the semi‐invariant natural killer T‐cell receptor towards structurally diverse CD1d‐restricted ligands

William C. Florence, J. McCluskey, J. Rossjohn, 2009, The EMBO journal.

The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs

Laura F. Dagley, P. W. Janes, J. Sandow, 2021, The Biochemical journal.

Over-production of dihydrofolate reductase leads to sulfa-dihydropteroate resistance in yeast.

I. Macreadie, O. Patel, K.P.D. Karnik, 2004, FEMS microbiology letters.

Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1

Weiwen Dai, O. Patel, I. Lucet, 2021, Communications Biology.

Structural basis for small molecule targeting of Doublecortin Like Kinase 1 DCLK1

Weiwen Dai, O. Patel, I. Lucet, 2021 .

α-Glucuronosyl and α-glucosyl diacylglycerides, natural killer T cell-activating lipids from bacteria and fungi†

Spencer J. Williams, J. Rossjohn, D. Godfrey, 2019, Chemical science.

Folic acid utilisation related to sulfa drug resistance in Saccharomyces cerevisiae.

J. Berglez, I. Macreadie, P. Coloe, 2001, FEMS microbiology letters.

Production of a functional dihydrofolate synthase with a cleavable poly-His tag in Saccharomyces cerevisiae

R. Fernley, I. Macreadie, P. Coloe, 2002, Biotechnology Letters.

Differential recognition of CD1d- α -galactosyl ceramide by the V β 8.2 and V β 7 semi-invariant NKT T-cell receptors

J. McCluskey, J. Rossjohn, D. Pellicci, 2009 .

Eph receptor signalling: from catalytic to non-catalytic functions

P. W. Janes, O. Patel, I. Lucet, 2019, Oncogene.

When two’s a crowd - Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3/Crk signaling

B. C. Lechtenberg, R. Daly, Weiwen Dai, 2022, bioRxiv.

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

D. Sinderen, J. McCluskey, J. Rossjohn, 2014, Nature.

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

James McCluskey, Ligong Liu, Zhenjun Chen, 2013, Nature Communications.

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

James McCluskey, Ted H. Hansen, Zhenjun Chen, 2012, The Journal of experimental medicine.

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

James McCluskey, John B. Furness, Ted H. Hansen, 2013, The Journal of experimental medicine.

Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors.

James McCluskey, Siew Siew Pang, Jamie Rossjohn, 2009, Immunity.

Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor

Jamie Rossjohn, J. Rossjohn, S. Gras, 2012, Nature Immunology.

Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors

G. Besra, T. Beddoe, J. McCluskey, 2011, Nature Immunology.

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

James McCluskey, Ligong Liu, David P. Fairlie, 2014, The Journal of experimental medicine.

Antigen recognition by CD1d-restricted NKT T cell receptors.

J. McCluskey, J. Rossjohn, D. Pellicci, 2010, Seminars in immunology.

The PEAK family of pseudokinases, their role in cell signalling and cancer

O. Patel, I. Lucet, James M. Murphy, 2020, The FEBS journal.

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor.

J. Rossjohn, A. Wilks, H. Treutlein, 2006, Blood.

Sulfa drugs strike more than once.

A. Nzila, I. Macreadie, O. Patel, 2004, Trends in parasitology.

Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1.

Weiwen Dai, C. Burns, M. Ernst, 2016, Structure.

CD1d protein structure determines species‐selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells

J. Rossjohn, P. Brennan, U. Zähringer, 2013, European journal of immunology.

Inhibition studies of sulfonamide-containing folate analogs in yeast.

J. Baell, R. Fernley, I. Macreadie, 2003, Microbial drug resistance.

PEAK3 pseudokinase represents a pro-migratory and -invasive signalling scaffold

R. Daly, Xiuquan Ma, O. Patel, 2021, bioRxiv.

Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association

S. Panjikar, R. Daly, Weiwen Dai, 2017, Nature Communications.

Distinct PEAK3 interactors and outputs expand the signaling potential of the PEAK pseudokinase family

R. Daly, Xiuquan Ma, O. Patel, 2022, Science Signaling.

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors

Spencer J. Williams, J. Rossjohn, D. Pellicci, 2019, Nature Communications.

Vβ2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen

G. Besra, J. McCluskey, J. Rossjohn, 2011, Proceedings of the National Academy of Sciences.

Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling

B. C. Lechtenberg, R. Daly, Weiwen Dai, 2023, Nature communications.

Saccharomyces cerevisiae expression vectors with thrombin-cleavable N- and C-terminal 6x(His) tags

R. Fernley, I. Macreadie, O. Patel, 2003, Biotechnology Letters.

Eph receptor signalling: from catalytic to non-catalytic functions

P. W. Janes, O. Patel, I. Lucet, 2019, Oncogene.

Adaptability of the semi‐invariant natural killer T‐cell receptor towards structurally diverse CD1d‐restricted ligands

William C. Florence, J. McCluskey, J. Rossjohn, 2009, The EMBO journal.

Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex*

G. Besra, S. Porcelli, O. Patel, 2012, The Journal of Biological Chemistry.

CD1d-lipid antigen recognition by the γδ TCR

T. Beddoe, J. Rossjohn, S. Gras, 2013, Nature Immunology.