David Knight

发表

Comparative Proteomic Analysis of Supportive and Unsupportive Extracellular Matrix Substrates for Human Embryonic Stem Cell Maintenance

M. Humphries, S. Kimber, Banu Iskender, 2013, The Journal of Biological Chemistry.

Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly

Adam Byron, David Knight, M. Humphries, 2015, Nature Cell Biology.

Improved LC-MS chromatographic alignment increases the accuracy of label-free quantitative proteomics: Comparison of spectral counting versus ion intensity-based proteomic quantification strategies

M. Humphries, A. Byron, J. Humphries, 2017, bioRxiv.

The effect of peptide adsorption on signal linearity and a simple approach to improve reliability of quantification☆

M. Humphries, A. Byron, David Knight, 2013, Journal of proteomics.

Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation

M. Humphries, C. Lawless, J. Humphries, 2020, The Journal of cell biology.

Definition of the fibroblast adhesome using multiplexed proximity biotinylation

M. Humphries, C. Lawless, J. Humphries, 2020, bioRxiv.

Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling

Julian N. Selley, M. Humphries, Guillaume Jacquemet, 2015, Nature Communications.

Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver

Julian N. Selley, M. Humphries, R. Goldin, 2012, Journal of proteome research.

Reciprocal priming between receptor tyrosine kinases at recycling endosomes orchestrates cellular signalling outputs

C. Francavilla, R. Clarke, K. Kowalczyk, 2021, bioRxiv.

Characterization of the Phospho-Adhesome by Mass Spectrometry-Based Proteomics.

M. Humphries, A. Byron, Nikki R. Paul, 2017, Methods in molecular biology.

(2020). Global proteomic analysis of insulin receptor interactors in glomerular podocytes. Wellcome Open Research, 5,

M. Humphries, Salman Hosawi, R. Coward, 2021 .

The Reduction Potential of the Active Site Disulfides of Human Protein Disulfide Isomerase Limits Oxidation of the Enzyme by Ero1α*

N. Bulleid, David Knight, Stacey Warwood, 2010, The Journal of Biological Chemistry.

A microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids

L. Griffith, M. Humphries, C. Cintas, 2021, Nature Materials.

Proteomic Analysis of Integrin-Associated Complexes Identifies RCC2 as a Dual Regulator of Rac1 and Arf6

Adam Byron, John W Pinney, Mark D Bass, 2009, Science Signaling.

Laser capture microdissection coupled mass spectrometry (LCM-MS) for spatially resolved analysis of formalin-fixed and stained human lung tissues

M. Schwartz, C. Lawless, David Knight, 2019, bioRxiv.

A role for repressive complexes and H3K9 di-methylation in PRDM5-associated brittle cornea syndrome.

Julian N. Selley, G. G. Galli, H. Venselaar, 2015, Human molecular genetics.

Pancreatic ductal adenocarcinoma cells employ integrin α6β4 to form hemidesmosomes and regulate cell proliferation.

M. Humphries, Aleksandr Mironov, J. Askari, 2022, Matrix biology : journal of the International Society for Matrix Biology.

Pancreatic ductal adenocarcinoma cells employ integrin α6β4 to form hemidesmosomes and regulate cell proliferation

M. Humphries, Aleksandr Mironov, J. Burns, 2021, bioRxiv.

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment

M. Humphries, S. E. Craig, J. Humphries, 2012, Proteomics.

Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and Transporters

K. Lea, J. Schageman, A. Rostami-Hodjegan, 2020, Clinical pharmacology and therapeutics.

An integrin-α4–14-3-3ζ–paxillin ternary complex mediates localised Cdc42 activity and accelerates cell migration

Christoph Ballestrem, David Knight, M. Humphries, 2009, Journal of Cell Science.

Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures

Julian N. Selley, R. Boot-Handford, D. Thornton, 2013, Biology Open.

Global analysis reveals the complexity of the human glomerular extracellular matrix.

Michael J. Randles, M. Humphries, Alexandre F. Carisey, 2014, Journal of the American Society of Nephrology : JASN.

Global proteomic analysis of insulin receptor interactors in glomerular podocytes

M. Humphries, R. Coward, R. Lennon, 2020, Wellcome open research.

A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting

Colin K. Choi, Christopher S. Chen, M. Humphries, 2015, Nature Communications.

Proteomic Analysis of Integrin Adhesion Complexes

M. Humphries, J. Humphries, David Knight, 2011, Science Signaling.

Giant worm-shaped ESCRT scaffolds surround actin-independent integrin clusters

Julian N. Selley, G. van den Bogaart, P. Heeringa, 2023, The Journal of cell biology.

Genetic Background is a Key Determinant of Glomerular Extracellular Matrix Composition and Organization.

Michael J. Randles, R. Korstanje, A. Woolf, 2015, Journal of the American Society of Nephrology : JASN.

Multi-regional alterations in glucose and purine metabolic pathways in the Parkinson’s disease dementia brain

R. Unwin, David Knight, Melissa Scholefield, 2023, NPJ Parkinson's disease.

Proteomic analysis of integrin‐associated complexes from mesenchymal stem cells

M. Humphries, S. Kimber, J. Askari, 2015, Proteomics. Clinical applications.