P. Johansson

发表

Ligand Binding Thermodynamics in Drug Discovery: Still a Hot Tip?

J. Ulander, S. Geschwindner, P. Johansson, 2015, Journal of medicinal chemistry.

Rv0216, a conserved hypothetical protein from Mycobacterium tuberculosis that is essential for bacterial survival during infection, has a double hotdog fold

T. Unge, P. Johansson, A. Castell, 2005, Protein science : a publication of the Protein Society.

Development and evaluation of a broad reacting SYBR-green based quantitative real-time PCR for the detection of different hantaviruses.

J. Klingström, M. Evander, C. Ahlm, 2013, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

The Sp1 transcription factor binds to the G-allele of the –1087 IL-10 gene polymorphism and enhances transcriptional activation

P. Johansson, T. Berglundh, L. Larsson, 2009, Genes and Immunity.

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

P. Cohen, A. Syvänen, L. Rönnblom, 2019, Annals of the rheumatic diseases.

Genetic variations in A 20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

P. Cohen, L. Rönnblom, S. Rantapää-Dahlqvist, 2019 .

PCR-generated linear DNA fragments utilized as a hantavirus DNA vaccine.

A. Holmström, F. Elgh, P. Johansson, 2002, Vaccine.

Structural analysis of the LDL receptor–interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site

T. Sixma, Hongwei Guo, P. Wan, 2020, The Journal of Biological Chemistry.

Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function.

T. Bergfors, S. Mowbray, T. Unge, 2005, Journal of molecular biology.

Mining Natural Products for Macrocycles to Drug Difficult Targets

Vasanthanathan Poongavanam, J. Kihlberg, S. Geschwindner, 2020, Journal of medicinal chemistry.

FAM3B PANDER and FAM3C ILEI represent a distinct class of signaling molecules with a non-cytokine-like fold.

Yafeng Xue, P. Johansson, S. Bäckström, 2013, Structure.

Enzymatic properties of native and deglycosylated hybrid aspen (Populus tremulaxtremuloides) xyloglucan endotransglycosylase 16A expressed in Pichia pastoris.

H. Brumer, T. Teeri, K. Piens, 2005, The Biochemical journal.

The interleukin-like epithelial-mesenchymal transition inducer ILEI exhibits a non-interleukin-like fold and is active as a domain-swapped dimer

A. Nyström, Á. Csiszár, P. Johansson, 2017, The Journal of Biological Chemistry.

Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity.

Clay W Scott, R. Bürli, J. Holenz, 2018, Journal of medicinal chemistry.

Dodecin Is the Key Player in Flavin Homeostasis of Archaea

D. Oesterhelt, M. Grininger, J. Wachtveitl, 2009, Journal of Biological Chemistry.

Crystallization and preliminary X-ray analysis of a xyloglucan endotransglycosylase from Populus tremula tremuloides

H. Brumer, T. Jones, T. Bergfors, 2003 .

Structural insight into allosteric modulation of protease-activated receptor 2

Patrik Johansson, Ali Jazayeri, Christoph Grebner, 2017, Nature.

New aminoimidazoles as β-secretase (BACE-1) inhibitors showing amyloid-β (Aβ) lowering in brain.

S. Eketjäll, B. Swahn, K. Kolmodin, 2012, Journal of medicinal chemistry.

Quaternary glucocorticoid receptor structure highlights allosteric interdomain communication

S. Postel, B. Klaholz, I. Billas, 2023, Nature Structural & Molecular Biology.

X-ray structure of Candida antarctica lipase A shows a novel lid structure and a likely mode of interfacial activation.

Patrik Johansson, Terese Bergfors, T. Bergfors, 2008, Journal of molecular biology.

Structural and biochemical characterization of a halophilic archaeal alkaline phosphatase.

M. Dyall-Smith, D. Oesterhelt, A. Wende, 2010, Journal of molecular biology.

Microarray technology for identification and distinction of hantaviruses

Patrik Johansson, Peter Nilsson, Fredrik Elgh, 2004, Journal of medical virology.

Implications of Local Puumala Hantavirus Genetics and Epidemiology for Diagnostics and Vaccine Development

P. Johansson, 2005 .

Molecular characterization of two hantavirus strains from different rattus species in Singapore

L. Ng, Relus Kek, G. Yap, 2010, Virology Journal.

Crystal Structures of a Poplar Xyloglucan Endotransglycosylase Reveal Details of Transglycosylation Acceptor Binding

H. Brumer, T. Teeri, Martin J. Baumann, 2004, The Plant Cell Online.

Crystal Structures of a Xyloglucan Endotransglycosylase Reveal Details of Transglycosylation Acceptor Binding

H. Brumer, T. Teeri, Martin J. Baumann, 2004 .

Crystallization and preliminary X-ray analysis of a xyloglucan endotransglycosylase from Populus tremula x tremuloides.

H. Brumer, T. Bergfors, T. Teeri, 2003, Acta crystallographica. Section D, Biological crystallography.

Inhibition of the fungal fatty acid synthase type I multienzyme complex

D. Oesterhelt, C. Vonrhein, M. Grininger, 2008, Proceedings of the National Academy of Sciences.

X-ray structure of peptidyl-prolyl cis-trans isomerase A from Mycobacterium tuberculosis.

S. Mowbray, T. Unge, P. Johansson, 2004, European journal of biochemistry.

Structural Studies of a Xyloglucan Endotransglycosylase from Populus tremula x tremuloides and Three Conserved Hypothetical Proteins from Mycobacterium tuberculosis

P. Johansson, 2006 .

Puumala hantavirus genetic variability in an endemic region (Northern Sweden).

F. Elgh, G. Olsson, C. Ahlm, 2008, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Crystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamily

Patrik Johansson, Margareta Ek, Stefan Geschwindner, 2013, Proceedings of the National Academy of Sciences.

MraY-antibiotic complex reveals details of tunicamycin mode of action.

J. Hakulinen, A. Snijder, P. Johansson, 2017, Nature chemical biology.

Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.

D. Oesterhelt, M. Grininger, P. Johansson, 2009, Structure.

Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1–Nrf2 Protein–Protein Interaction

P. Matricon, R. Lewis, J. Kihlberg, 2022, Journal of medicinal chemistry.

Structure and biophysical characterization of the human full-length neurturin–GFRa2 complex: A role for heparan sulfate in signaling

Tomas Åkerud, P. Davidsson, A. Aagaard, 2018, The Journal of Biological Chemistry.

Structure and function of Rv0130, a conserved hypothetical protein from Mycobacterium tuberculosis

P. Johansson, A. Castell, K. Bäckbro, 2006, Protein science : a publication of the Protein Society.

Core refinement toward permeable β-secretase (BACE-1) inhibitors with low hERG activity.

J. Malmström, P. Johansson, A. Kers, 2013, Journal of medicinal chemistry.

Complete gene sequence of a human Puumala hantavirus isolate, Puumala Umeå/hu: sequence comparison and characterisation of encoded gene products.

A. Holmström, F. Elgh, C. Ahlm, 2004, Virus research.

New aminoimidazoles as beta-secretase (BACE-1) inhibitors showing amyloid-beta (A beta ) lowering in brain.

S. Eketjäll, B. Swahn, K. Strömberg, 2012 .

Development of a plate-based optical biosensor fragment screening methodology to identify phosphodiesterase 10A inhibitors.

Clay W Scott, S. Geschwindner, R. Horsefield, 2013, Journal of medicinal chemistry.

Structure of the methyltransferase domain from the Modoc virus, a flavivirus with no known vector.

B. Coutard, T. Unge, P. Johansson, 2009, Acta crystallographica. Section D, Biological crystallography.