W. E. A. de Witte

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.

Leigh A. Stoddart, R. Wade, R. Leurs, 2017, Drug discovery today.

The influence of drug distribution and drug‐target binding on target occupancy: The rate‐limiting step approximation

P. H. van der Graaf, G. Vauquelin, W. E. A. de Witte, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

In vivo Target Residence Time and Kinetic Selectivity: The Association Rate Constant as Determinant.

M. Danhof, P. H. van der Graaf, W. E. A. de Witte, 2016, Trends in pharmacological sciences.

Assessment of Interspecies Differences in Drug-Induced QTc Interval Prolongation in Cynomolgus Monkeys, Dogs and Humans

M. Danhof, S. Visser, O. Della Pasqua, 2015, Pharmaceutical Research.

A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy

A. IJzerman, H. de Vries, L. Heitman, 2017, Scientific Reports.