E. Ruggiero

发表

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy

E. Ruggiero, S. Richter, 2018, Nucleic acids research.

Viral G-quadruplexes: New frontiers in virus pathogenesis and antiviral therapy

E. Ruggiero, S. Richter, 2020, Annual Reports in Medicinal Chemistry.

G-Quadruplex Targeting in the Fight against Viruses: An Update

E. Ruggiero, S. Richter, Irene Zanin, 2021, International journal of molecular sciences.

Fused in Liposarcoma Protein, a New Player in the Regulation of HIV-1 Transcription, Binds to Known and Newly Identified LTR G-Quadruplexes

J. Plavec, M. Scalabrin, E. Ruggiero, 2022, ACS infectious diseases.

Human Virus Genomes Are Enriched in Conserved Adenine/Thymine/Uracil Multiple Tracts That Pause Polymerase Progression

E. Lavezzo, S. Toppo, J. Plavec, 2022, Frontiers in Microbiology.

Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1

L. Flamand, E. Ruggiero, S. Richter, 2021, Viruses.

One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists.

K. Varani, F. Vincenzi, P. Borea, 2015, Journal of medicinal chemistry.

7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as selective CB(2) cannabinoid receptor ligands: structural investigations around a novel class of full agonists.

K. Varani, F. Vincenzi, M. Targa, 2012, Journal of medicinal chemistry.

Targeting G-quadruplexes to achieve antiviral activity

E. Ruggiero, S. Richter, 2022, Bioorganic & medicinal chemistry letters.

In vitro effect of reproterol upon pulmonary, cardiac, vascular and intestinal 3′, 5′‐monophosphate phosphodiesterase nucleoside

M. Matera, E. Ruggiero, E. Marmo, 1982, The Journal of pharmacy and pharmacology.

New Synthesis of Diazepino[3,2,1‐ij]quinoline and Pyrido[1,2,3‐de]quinoxalines via Addition–Elimination Followed by Cycloacylation

P. Baraldi, E. Ruggiero, M. A. Tabrizi, 2014 .

The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma

G. Schotta, J. Plavec, F. Cernilogar, 2021, Nucleic acids research.

A dynamic i-motif with a duplex stem-loop in the long terminal repeat promoter of the HIV-1 proviral genome modulates viral transcription

J. Plavec, E. Ruggiero, S. Richter, 2019, Nucleic acids research.

Stable and Conserved G-Quadruplexes in the Long Terminal Repeat Promoter of Retroviruses

E. Ruggiero, S. Richter, M. Nadai, 2019, ACS infectious diseases.

The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes

Giorgio Palù, Rosalba Perrone, G. Palù, 2017, Scientific Reports.

Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB(2) cannabinoid receptor inverse agonists.

Cristina Tintori, Tiziano Tuccinardi, Pier Andrea Borea, 2013, Journal of medicinal chemistry.

Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

C. Ghelardini, J. Gertsch, L. De Stefano, 2018, Journal of medicinal chemistry.

Synthesis and structure activity relationship investigation of triazolo[1,5-a]pyrimidines as CB2 cannabinoid receptor inverse agonists.

K. Varani, T. Tuccinardi, F. Vincenzi, 2016, European journal of medicinal chemistry.

Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH).

T. Tuccinardi, A. Martinelli, P. Baraldi, 2015, European journal of medicinal chemistry.

Genome-wide mapping of i-motifs reveals their association with transcription regulation in live human cells

E. Ruggiero, S. Richter, Sara Lago, 2023, Nucleic acids research.