S. Cai

发表

Endogenous Nodal promotes melanoma undergoing epithelial-mesenchymal transition via Snail and Slug in vitro and in vivo.

Jun Du, Hong-Sheng Wang, Q. Guo, 2015, American journal of cancer research.

A SIRT3/AMPK/autophagy network orchestrates the protective effects of trans-resveratrol in stressed peritoneal macrophages and RAW 264.7 macrophages.

Qi Wang, R. He, S. Cai, 2016, Free radical biology & medicine.

The TGF‐β‐induced up‐regulation of NKG2DLs requires AKT/GSK‐3β‐mediated stabilization of SP1

Jun Du, Hong-Sheng Wang, S. Cai, 2017, Journal of cellular and molecular medicine.

Plasma Pharmacokinetic and Heart Distribution Studies of Z-GP-EPI, a Hypocardiotoxic Prodrug of Epirubicin

S. Cai, Fang-Lan Liu, Guang-xue Liu, 2015 .

Original Article Endogenous Nodal promotes melanoma undergoing epithelial-mesenchymal transition via Snail and Slug in vitro and in vivo

Jun Du, Hong-Sheng Wang, Q. Guo, 2015 .

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype

Hongsheng Wang, Jun Du, Hao Liu, 2016, Oncotarget.

TGF-β and EGF induced HLA-I downregulation is associated with epithelial-mesenchymal transition (EMT) through upregulation of snail in prostate cancer cells.

Hao Wang, Jun Du, Fan Zhang, 2015, Molecular immunology.

Histone deacetylase inhibitor induction of epithelial-mesenchymal transitions via up-regulation of Snail facilitates cancer progression.

Hao Wang, Jun Du, Fan Zhang, 2013, Biochimica et biophysica acta.

The Reversal Effects of 3-Bromopyruvate on Multidrug Resistance In Vitro and In Vivo Derived from Human Breast MCF-7/ADR Cells

Hao Wang, Jun Du, Hao Wang, 2014, PloS one.

Synergistic effects of nimesulide and 5-fluorouracil on tumor growth and apoptosis in the implanted hepatoma in mice.

Xiao-Hong Li, S. Cai, X. Zhong, 2003, World journal of gastroenterology.

Identification of potential pathways involved in the induction of cell cycle arrest and apoptosis by a new 4-arylidene curcumin analogue T63 in lung cancer cells: a comparative proteomic analysis.

Jun Du, Hao Liu, Fan Zhang, 2014, Molecular bioSystems.

Possible Involvement Of P‐Glycoprotein In The Biliary Excretion Of Grepafloxacin

T. Hasegawa, K. Takagi, K. Kitaichi, 2002, Clinical and experimental pharmacology & physiology.

Evaluation of the tumor targeting of a FAPα-based doxorubicin prodrug

Jun Du, Rui Fang, S. Cai, 2011, Journal of drug targeting.

Development of a LC-MS/MS Method for a New Ortho-aryl Chalcone Compound of OC26 and its Application to Bile

S. Cai, Xia Gan, Jun Xu, 2020 .

Changes in the proteomic profile during the differential polarization status of the human monocyte‐derived macrophage THP‐1 cell line

Hao Wang, Hongsheng Wang, Jun Du, 2015, Proteomics.

A new tumor vaccine: FAPτ-MT elicits effective antitumor response by targeting indolamine2,3-dioxygenase in antigen presenting cells

Jun Du, Rui Fang, Ge Zhang, 2011, Cancer biology & therapy.

The clinical efficacy and safety evaluation of ticagrelor for acute coronary syndrome in general ACS patients and diabetic patients: A systematic review and meta-analysis

S. Cai, Xin Jiang, Jun Xu, 2017, PloS one.

Population Pharmacokinetics in China: The Dynamics of Intravenous Voriconazole in Critically Ill Patients with Pulmonary Disease.

Yimin Li, Xiaoqing Liu, S. Cai, 2015, Biological & pharmaceutical bulletin.

QSAR Studies on Andrographolide Derivatives as α-Glucosidase Inhibitors

Jiaolin Bao, Yuqiang Wang, S. Cai, 2010, International journal of molecular sciences.

Enhancement of dendritic cell-tumor fusion vaccine potency by indoleamine-pyrrole 2,3-dioxygenase inhibitor, 1-MT

Jun Du, P. Liu, S. Cai, 2008, Journal of Cancer Research and Clinical Oncology.

Prevention of spontaneous tumor development in a ret transgenic mouse model by ret peptide vaccination with indoleamine 2,3-dioxygenase inhibitor 1-methyl tryptophan.

Jun Du, Xiaokun Li, S. Cai, 2009, Cancer research.

The role of indoleamine 2,3-dioxygenase (IDO) in immune tolerance: focus on macrophage polarization of THP-1 cells.

Hao Wang, Jun Du, Fan Zhang, 2014, Cellular immunology.

Trichostatin A, a histone deacetylase inhibitor, reverses epithelial-mesenchymal transition in colorectal cancer SW480 and prostate cancer PC3 cells.

Jun Du, Hao Wang, S. Cai, 2015, Biochemical and biophysical research communications.

Loss of C-terminal alpha-helix decreased SDF-1alpha-mediated signaling and chemotaxis without influencing CXCR4 internalization.

Xiao-Hong Li, S. Cai, S. Cai, 2004, Acta pharmacologica Sinica.

Stabilization of Snail through AKT/GSK-3β signaling pathway is required for TNF-α-induced epithelial-mesenchymal transition in prostate cancer PC3 cells.

Jun Du, Fan Zhang, Hong-Sheng Wang, 2013, European journal of pharmacology.

SDF-1/54-DCN: a novel recombinant chimera with dual inhibitory effects on proliferation and chemotaxis of tumor cells.

Jun Du, S. Cai, Zhigang Guo, 2008, Biological & pharmaceutical bulletin.

Cloning and characterizing mutated human stromal cell-derived factor-1 (SDF-1): C-terminal alpha-helix of SDF-1alpha plays a critical role in CXCR4 activation and signaling, but not in CXCR4 binding affinity.

Jun Du, S. Cai, Jian Xiao, 2006, Experimental hematology.

Mixed nanomicelles as potential carriers for systemic delivery of Z-GP-Dox, an FAPα-based doxorubicin prodrug: formulation and pharmacokinetic evaluation

S. Cai, Baojian Wu, Xingwang Zhang, 2015, International journal of nanomedicine.

Z-GP Modification to CI-994, a Histone Deacetylase Inhibitor and the Application in Targeting Carcinoma Chemotherapy

Yuanyuan Deng, S. Cai, Jun Xu, 2013 .

Synthesis and antitumor activity evaluations of albumin-binding prodrugs of CC-1065 analog.

J. Larrick, Yuqiang Wang, S. C. Wright, 2008, Bioorganic & medicinal chemistry.

Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes

Jun Du, P. Liu, Ge Zhang, 2009, BMC Cancer.

Histone deacetylase inhibitors deplete myeloid-derived suppressor cells induced by 4T1 mammary tumors in vivo and in vitro

Ziqian Li, Jun Du, Hong-Sheng Wang, 2017, Cancer Immunology, Immunotherapy.

Serum from rabbit orally administered cobra venom inhibits growth of implanted hepatocellular carcinoma cells in mice.

Xiao-Hong Li, S. Cai, Kai-he Ye, 2003, World journal of gastroenterology.

The SAR studies on FAP inhibitors as tumor-targeted agents

S. Cai, Nong Wu, Jun Xu, 2015, Medicinal Chemistry Research.

Nimesulide inhibits tumor growth in mice implanted hepatoma: overexpression of Bax over Bcl-2.

Xiao-Hong Li, S. Cai, X. Ren, 2003, Acta pharmacologica Sinica.

Epithelial–Mesenchymal Transition (EMT) Induced by TNF-α Requires AKT/GSK-3β-Mediated Stabilization of Snail in Colorectal Cancer

Ge Zhang, Fan Zhang, Hao Wang, 2013, PloS one.

Anti-apoptotic effect of hepatocyte growth factor from actinomycin D in hepatocyte-derived HL7702 cells is associated with activation of PI3K/Akt signaling.

Xiaokun Li, L. Cai, S. Cai, 2006, Toxicology letters.

T63, a new 4-arylidene curcumin analogue, induces cell cycle arrest and apoptosis through activation of the reactive oxygen species-FOXO3a pathway in lung cancer cells.

Jun Du, Hao Liu, Fan Zhang, 2012, Free radical biology & medicine.

FOXO3a modulates WNT/β-catenin signaling and suppresses epithelial-to-mesenchymal transition in prostate cancer cells.

Hongsheng Wang, Jun Du, Hao Liu, 2015, Cellular signalling.

T 63 , a new 4-arylidene curcumin analogue , induces cell cycle arrest and apoptosis through activation of the reactive oxygen species – FOXO 3 a pathway in lung cancer cells

Jun Du, Hao Liu, Fan Zhang, 2012 .

Snail regulated by PKC/GSK-3β pathway is crucial for EGF-induced epithelial-mesenchymal transition (EMT) of cancer cells

Jun Du, Hao Liu, Hong-Sheng Wang, 2014, Cell and Tissue Research.

CCL21 Facilitates Chemoresistance and Cancer Stem Cell-Like Properties of Colorectal Cancer Cells through AKT/GSK-3β/Snail Signals

Jun Du, Hong-Sheng Wang, Hao Wang, 2015, Oxidative medicine and cellular longevity.

Nodal promotes aggressive phenotype via Snail-mediated epithelial-mesenchymal transition in murine melanoma.

Jun Du, Hao Wang, Q. Guo, 2013, Cancer letters.

Inhibitory effect of erythromycin on P-glycoprotein-mediated biliary excretion of doxorubicin in rats.

T. Hasegawa, T. Nabeshima, K. Kitaichi, 2000, Anticancer research.

AP-1 confers resistance to anti-cancer therapy by activating XIAP

Y. Wang, Ziqian Li, Jun Du, 2018, Oncotarget.

Acquisition of epithelial-mesenchymal transition phenotype and cancer stem cell-like properties in cisplatin-resistant lung cancer cells through AKT/β-catenin/Snail signaling pathway.

Hao Wang, Jun Du, Fan Zhang, 2014, European journal of pharmacology.

Participation of CCL1 in Snail-Positive Fibroblasts in Colorectal Cancer Contribute to 5-Fluorouracil/Paclitaxel Chemoresistance

Y. Wang, Ziqian Li, Jun Du, 2017, Cancer research and treatment : official journal of Korean Cancer Association.

AKT/GSK-3β regulates stability and transcription of snail which is crucial for bFGF-induced epithelial-mesenchymal transition of prostate cancer cells.

Jun Du, Hao Liu, Fan Zhang, 2014, Biochimica et biophysica acta.

Targeting eradication of malignant cells derived from human bone marrow mesenchymal stromal cells.

K. Sung, Jun Du, Li Yang, 2010, Experimental cell research.

Interfering with cellular signaling pathways enhances sensitization to combined sodium butyrate and GCV treatment in EBV-positive tumor cells.

Jun Du, Ge Zhang, S. Cai, 2008, Virus research.

Nodal signaling modulates the expression of Oct-4 via nuclear translocation of β-catenin in lung and prostate cancer cells.

Ziqian Li, Jun Du, Hong-Sheng Wang, 2016, Archives of biochemistry and biophysics.

Sodium butyrate down-regulation of indoleamine 2, 3-dioxygenase at the transcriptional and post-transcriptional levels.

Jun Du, Rui Fang, Ge Zhang, 2010, The international journal of biochemistry & cell biology.

Binding activity of H-Ras is necessary for in vivo inhibition of ASK1 activity

Jun Du, F. Nagase, S. Cai, 2004, Cell Research.

Autophagy is involved in TGF-β1-induced protective mechanisms and formation of cancer-associated fibroblasts phenotype in tumor microenvironment

Jun Du, Hong-Sheng Wang, Liu Yang, 2015, Oncotarget.

Methylglyoxal downregulates Raf-1 protein through a ubiquitination-mediated mechanism.

Jun Du, S. Cai, J. Zeng, 2006, The international journal of biochemistry & cell biology.

Toxicological profile and safety pharmacology of a single dose of fibroblast activation protein-&agr;-based doxorubicin prodrug: in-vitro and in-vivo evaluation

S. Cai, Jun Xu, Ying Pan, 2018, Anti-cancer drugs.

Phenotypic Knockout of CXCR4 by a Novel Recombinant Protein TAT/54R/KDEL Inhibits Tumors Metastasis

Jun Du, Jun Du, Rui Fang, 2009, Molecular Cancer Research.

A novel recombinant protein TAT–GFP–KDEL with dual-function of penetrating cell membrane and locating at endoplasm reticulum

Jun Du, S. Cai, Yi Tan, 2009, Journal of drug targeting.

Nodal promotes the generation of M2‐like macrophages and downregulates the expression of IL‐12

Hao Wang, Jun Du, Fan Zhang, 2014, European journal of immunology.

Nodal Facilitates Differentiation of Fibroblasts to Cancer-Associated Fibroblasts that Support Tumor Growth in Melanoma and Colorectal Cancer

Ziqian Li, Jiawang Zhou, Junjie Zhang, 2019, Cells.

Asclepiasterol, a novel C21 steroidal glycoside derived from Asclepias curassavica, reverses tumor multidrug resistance by down-regulating P-glycoprotein expression

W. Yuan, S. Cai, Renqi Jiang, 2016, Oncotarget.

Calotropin from Asclepias curasavica induces cell cycle arrest and apoptosis in cisplatin-resistant lung cancer cells.

S. Cai, R. Jiang, Fang-Lan Liu, 2016, Biochemical and biophysical research communications.

Long form collapsin response mediator protein-1 promotes the migration and invasion of osteosarcoma cells.

Z. Zha, S. Cai, Huige Hou, 2016, Oncology letters.

A novel FAP&agr;‐based Z‐Gly‐Pro epirubicin prodrug for improving tumor‐targeting chemotherapy

S. Cai, Weiqi Yuan, Jun Xu, 2017, European journal of pharmacology.

Nodal Facilitates Differentiation of Fibroblasts to Cancer-Associated Fibroblasts that Support Tumor Growth in Melanoma and Colorectal Cancer

Ziqian Li, Jiawang Zhou, Junjie Zhang, 2019, Cells.

Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF‐I‐mediated cell growth response by methylglyoxal

Jun Du, T. Miyata, A. Akhand, 2003, Journal of cellular biochemistry.

Studies on the Anti-Proliferative Effects and Molecular Mechanism of a Novel Small Molecular BOC26P in Breast Cancer

Shiying Li, S. Cai, Jun Xu, 2020 .

Identification of TBK1 and IKKε, the non-canonical IκB kinases, as crucial pro-survival factors in HTLV-1-transformed T lymphocytes.

S. Cai, Hua Cheng, Huan Zhang, 2016, Leukemia research.

The synergistic effects of CXCR4 and EGFR on promoting EGF-mediated metastasis in ovarian cancer cells.

Jun Du, S. Cai, Zhigang Guo, 2007, Colloids and surfaces. B, Biointerfaces.

Erratum to “Corrigendum to “The synergistic effects of CXCR4 and EGFR on promoting EGF-mediated metastasis in ovarian cancer cells” [Colloids Surf. B 60 (2007) 1–6]”

Jun Du, S. Cai, Zhigang Guo, 2007 .

Interfering with cellular signaling pathways enhances sensitization to combined sodium butyrate and GCV treatment in EBV-positive tumor cells.

Jun Du, Ge Zhang, S. Cai, 2008, Virus Research.

[Preliminary study on molecular mechanism of curcumine anti-mouse melanoma].

S. Cai, Xiao-kun Li, Hongyuan Chen, 2008, Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.

Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes

Jun Du, Ge Zhang, S. Cai, 2009, BMC Cancer.