O. Filhol

发表

Spatial organization of the extracellular matrix regulates cell–cell junction positioning

H. Guillou, M. Théry, Qingzong Tseng, 2012, Proceedings of the National Academy of Sciences.

A phosphatase cascade by which rewarding stimuli control nucleosomal response

Paul Greengard, Angus C. Nairn, Miriam Matamales, 2008, Nature.

A new micropatterning method of soft substrates reveals that different tumorigenic signals can promote or reduce cell contraction levels.

Manuel Théry, Matthieu Piel, Odile Filhol, 2011, Lab on a chip.

Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction.

Caroline Barette, Pascal Dumy, Béatrice Laudet, 2007, The Biochemical journal.

Structure-based design of small peptide inhibitors of protein kinase CK 2 subunit interaction

A. Metz, O. Dideberg, O. Renaudet, 2007 .

DSIR: Assessing the Design of Highly Potent siRNA by Testing a Set of Cancer-Relevant Target Genes

Jean-Philippe Vert, Christian Lajaunie, Nicolas Foveau, 2012, PloS one.

Protein Kinase CK2 in Health and Disease

O. Filhol, C. Cochet, 2009, Cellular and Molecular Life Sciences.

Dysregulated Expression of Protein Kinase CK2 in Renal Cancer

J. Long, M. Laramas, P. Champelovier, 2015 .

A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C

O. Filhol, C. Cochet, Q. Vega, 1992 .

Dynamic Localization/Association of Protein Kinase CK2 Subunits in Living Cells

Odile Filhol, Claude Cochet, O. Filhol, 2002, Annals of the New York Academy of Sciences.

p53-dependent inhibition of mammalian cell survival by a genetically selected peptide aptamer that targets the regulatory subunit of protein kinase CK2

P. Colas, O. Filhol, C. Cochet, 2006, Oncogene.

A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C

S. Rhee, O. Filhol, C. Cochet, 1992, Molecular and cellular biology.

The disruption of adherens junctions is associated with a decrease of E-cadherin phosphorylation by protein kinase CK2.

D. Schmitt, E. Chambaz, C. Grangeasse, 2000, Experimental cell research.

Live-Cell Fluorescence Imaging Reveals the Dynamics of Protein Kinase CK2 Individual Subunits

C. Souchier, O. Filhol, C. Cochet, 2003, Molecular and Cellular Biology.

Protein kinase CK2 contributes to placental development: physiological and pathological implications

N. Alfaidy, Daniel Vaiman, O. Filhol, 2019, Journal of Molecular Medicine.

Nuclear localization of protein kinase CK2 catalytic subunit (CK2alpha) is associated with poor prognostic factors in human prostate cancer.

F. Ringeisen, M. Laramas, O. Filhol, 2007, European journal of cancer.

Direct Identification of a Polyamine Binding Domain on the Regulatory Subunit of the Protein Kinase Casein Kinase 2 by Photoaffinity Labeling (*)

E. Chambaz, J. Behr, O. Filhol, 1995, The Journal of Biological Chemistry.

Polyamine binding activity of casein kinase II.

E. Chambaz, O. Filhol, C. Cochet, 1991, Biochemical and biophysical research communications.

Interaction between the epidermal growth factor receptor and phosphoinositide kinases.

T. Hunter, B. Payrastre, O. Filhol, 1991, The Journal of biological chemistry.

Regulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cells

V. Rangnekar, J. Eriksson, A. Hammann, 2014, Cell Death and Disease.

NLRP7 Promotes Choriocarcinoma Growth and Progression through the Establishment of an Immunosuppressive Microenvironment

R. Slim, V. Sapin, N. Alfaidy, 2021, Cancers.

A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1

T. Soderling, L. Tsai, Young T. Kwon, 1996, Molecular and cellular biology.

In Search of Small Molecule Inhibitors Targeting the Flexible CK2 Subunit Interface

O. Filhol, C. Cochet, M. Le Borgne, 2017, Pharmaceuticals.

Extracellular endosulfatase Sulf-2 harbours a chondroitin/dermatan sulfate chain that modulates its enzyme activity

R. Daniel, G. Larson, H. Lortat-Jacob, 2021, bioRxiv.

CK2β Is a Gatekeeper of Focal Adhesions Regulating Cell Spreading

Delphine Pflieger, C. Albigès-Rizo, C. Battail, 2022, Frontiers in Molecular Biosciences.

Baculovirus-directed expression of human prostatic steroid 5α-reductase 1 in an active form

pierre-Marie Martin, O. Filhol, S. Délos, 1993, The Journal of Steroid Biochemistry and Molecular Biology.

Characterization of two different cytoplasmic protein tyrosine kinases from human breast cancer.

M. Bolla, E. Chambaz, O. Filhol, 1997, Carcinogenesis.

Combined inhibition of PI3K and Src kinases demonstrates synergistic therapeutic efficacy in clear-cell renal carcinoma

O. Bastien, P. Champelovier, O. Filhol, 2018, Oncotarget.

Protein kinase CK2 controls T‐cell polarization through dendritic cell activation in response to contact sensitizers

M. Pallardy, S. Chollet-Martin, Y. Gallais, 2017, Journal of leukocyte biology.

Modulatory role of the anti-apoptotic protein kinase CK2 in the sub-cellular localization of Fas associated death domain protein (FADD).

Y. Couté, C. Hue, Anne-Marie Hesse, 2015, Biochimica et biophysica acta.

Protein kinase CK2 and cell polarity

Nathalie Theis-Febvre, A. Deshiere, O. Filhol, 2008, Molecular and Cellular Biochemistry.

Crystallization and preliminary x-ray diffraction analysis of the regulatory subunit of human protein kinase CK2.

E. Chambaz, O. Dideberg, D. Leroy, 1999, Acta crystallographica. Section D, Biological crystallography.

Editorial: in vitro and in vivo non-clinical models of kidney cancers

T. Massfelder, V. Dormoy, O. Filhol, 2022, Frontiers in Oncology.

Adenovirus infection targets the cellular protein kinase CK2 and RNA‐activated protein kinase (PKR) into viral inclusions of the cell nucleus

M. Rosa-Calatrava, S. Souquère-Besse, E. Pichard, 2002, Microscopy research and technique.

Casein kinase II and polyamines may interact in the response of adrenocortical cells to their trophic hormone.

E. Chambaz, O. Filhol, C. Cochet, 1991, Biochemical and biophysical research communications.

Searching interaction partners of protein kinase CK2β subunit by two-hybrid screening

E. Chambaz, O. Filhol, C. Cochet, 2004, Molecular and Cellular Biochemistry.

Identification of a cryptic protein kinase CK2 phosphorylation site in human complement protease C1r, and its use to probe intramolecular interaction

N. Thielens, G. Arlaud, Y. Pétillot, 1996, FEBS letters.

Binding of Polyamines to an Autonomous Domain of the Regulatory Subunit of Protein Kinase CK2 Induces a Conformational Change in the Holoenzyme

J. Hériché, E. Chambaz, D. Leroy, 1997, The Journal of Biological Chemistry.

Dissecting subdomains involved in multiple functions of the CK2β subunit

E. Chambaz, D. Leroy, O. Filhol, 2004, Molecular and Cellular Biochemistry.

2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action.

R. Abagyan, R. Hartmann, I. Kufareva, 2019, Journal of medicinal chemistry.

Quaternary Structure of Casein Kinase 2

E. Chambaz, J. Langowski, O. Filhol, 1995, The Journal of Biological Chemistry.

Protein kinase CK2 in breast cancer: the CK2β regulatory subunit takes center stage in epithelial plasticity

O. Filhol, C. Cochet, Y. Wallez, 2015, Cellular and Molecular Life Sciences.

CK2β-regulated signaling controls B cell differentiation and function

A. D. Dei Tos, C. Tripodo, N. Vitulo, 2023, Frontiers in Immunology.

CIGB-300 anticancer peptide regulates the protein kinase CK2-dependent phosphoproteome

Osmany Guirola, Y. Perera, G. Padrón, 2020, Molecular and Cellular Biochemistry.

Identification of chemical inhibitors of protein-kinase CK2 subunit interaction

Y. Wong, V. Moucadel, R. Prudent, 2008, Molecular and Cellular Biochemistry.

Visualization and molecular analysis of nuclear import of protein kinase CK2 subunits in living cells

O. Filhol, C. Cochet, V. Martel, 2004, Molecular and Cellular Biochemistry.

Unbalanced expression of CK2 kinase subunits is sufficient to drive epithelial-to-mesenchymal transition by Snail1 induction

Y. Couté, Y. Vandenbrouck, E. Duchemin-Pelletier, 2013, Oncogene.

The tight association of protein kinase CK2 with plasma membranes is mediated by a specific domain of its regulatory beta-subunit.

E. Chambaz, D. Leroy, O. Filhol, 1998, Biochimica et biophysica acta.

Role of CK2 in the Control of Cell Plasticity in Breast Carcinoma Progression

A. Deshiere, O. Filhol, C. Cochet, 2013 .

Fibroblast Growth Factor-2 Binds to the Regulatory β Subunit of CK2 and Directly Stimulates CK2 Activity toward Nucleolin*

F. Amalric, O. Filhol, C. Cochet, 1996, The Journal of Biological Chemistry.

The size-speed-force relationship governs migratory cell response to tumorigenic factors

Manuel Théry, Jean-Louis Martiel, Gaelle Letort, 2017, Molecular biology of the cell.

Heterogeneity of single-cell mechanical responses to tumorigenic factors

Aldo Leal-Egaña, A. Christ, J. Martiel, 2016, bioRxiv.

A Zinc Ribbon Motif Is Essential for the Formation of Functional Tetrameric Protein Kinase CK2

O. Filhol, C. Cochet, M. Benitez, 2005 .

Protein kinase CK2α subunit over-expression correlates with metastatic risk in breast carcinomas: quantitative immunohistochemistry in tissue microarrays.

D. Birnbaum, J. Iovanna, P. Bonnier, 2011, European journal of cancer.

Protein kinase CK2: a new view of an old molecular complex

J. Martiel, O. Filhol, C. Cochet, 2004, EMBO reports.

COL7A1 Expression Improves Prognosis Prediction for Patients with Clear Cell Renal Cell Carcinoma Atop of Stage

O. Filhol, C. Cochet, Laurent Guyon, 2023, bioRxiv.

Ex-Vivo Treatment of Tumor Tissue Slices as a Predictive Preclinical Method to Evaluate Targeted Therapies for Patients with Renal Carcinoma

J. Long, O. Filhol, C. Cochet, 2020, Cancers.

Protein Kinase CK2 Phosphorylation of EB2 Regulates Its Function in the Production of Epstein-Barr Virus Infectious Viral Particles

H. Drobecq, N. Sergeant, O. Filhol, 2007, Journal of Virology.

The Multifunctional Herpes Simplex Virus IE63 Protein Interacts with Heterogeneous Ribonucleoprotein K and with Casein Kinase 2*

R. Everett, J. Clements, O. Filhol, 1999, The Journal of Biological Chemistry.

Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors

R. Abagyan, P. Brear, I. Kufareva, 2019, Scientific Reports.

Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger‐mediated dimerization

E. Chambaz, O. Dideberg, L. Chantalat, 1999, The EMBO journal.

Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2.

C. Nguyen, J. Florent, V. Moucadel, 2010, Cancer research.

DNA topoisomerase II and casein kinase II associate in a molecular complex that is catalytically active.

E. Chambaz, A. Larsen, K. Bojanowski, 1993, The Journal of biological chemistry.

Polarity Reversal by Centrosome Repositioning Primes Cell Scattering during Epithelial-to-Mesenchymal Transition.

G. Blin, M. Théry, Qingzong Tseng, 2017, Developmental cell.

Chemical features of the protein kinase CK2 polyamine binding site.

E. Chambaz, J. Delcros, D. Leroy, 1997, Biochemistry.

Mitotic Phosphorylation of DNA Topoisomerase II α by Protein Kinase CK2 Creates the MPM-2 Phosphoepitope on Ser-1469*

A. Escargueil, A. Larsen, S. Plisov, 2000, The Journal of Biological Chemistry.

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth.

S. Knapp, A. di Pietro, C. Nguyen, 2012, Cancer research.

HIRIP3 is a nuclear phosphoprotein interacting with and phosphorylated by the serine-threonine kinase CK2

M. Lipinski, F. Galisson, O. Filhol, 2007, Biological chemistry.

Cooperative Blockade of CK2 and ATM Kinases Drives Apoptosis in VHL-Deficient Renal Carcinoma Cells through ROS Overproduction

J. Long, F. Chalmel, M. Fauvarque, 2021, Cancers.

Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes

M. Greenblatt, Jung-Min Kim, B. Boldyreff, 2022, Cell Death & Differentiation.

Protein kinase CK2 regulates CDC25B phosphatase activity

B. Monsarrat, V. Baldin, Nathalie Theis-Febvre, 2003, Oncogene.

Casein kinase II and the tumor suppressor protein P53 associate in a molecular complex that is negatively regulated upon P53 phosphorylation.

C. Delphin, J. Baudier, E. Chambaz, 1992, The Journal of biological chemistry.

Characterization of RAGE and CK2 Expressions in Human Fetal Membranes

G. Marceau, V. Sapin, O. Filhol, 2023, International journal of molecular sciences.

AB668, a novel highly selective protein kinase CK2 inhibitor with a distinct anti-tumor mechanism as compared to CX-4945 and SGC-CK2-1

J. Delcros, J. Guichou, I. Krimm, 2022, bioRxiv.

Visualization and molecular analysis of nuclear import of protein kinase CK2 subunits in living cells.

O. Filhol, C. Cochet, V. Martel, 2001 .

Protein Kinase CK2 Phosphorylation of EB2 Regulates Its Function in the Production of Epstein-Barr Virus Infectious Viral Particles (cid:1)

H. Drobecq, O. Filhol, C. Cochet, 2007 .

Targeting AU-rich element-mediated mRNA decay with a truncated active form of the zinc-finger protein TIS11b/BRF1 impairs major hallmarks of mammary tumorigenesis

N. Cherradi, J. Feige, O. Filhol, 2019, Oncogene.

Stem Cell-Like Properties of CK2β-down Regulated Mammary Cells

B. Mograbi, M. Théry, E. Duchemin-Pelletier, 2017, Cancers.

Protein Kinases Curb Cell Death

O. Filhol, C. Cochet, 2011, Science Signaling.

The Antiapoptotic Protein ICBP90 Is a Target for Protein Kinase 2

C. Bronner, M. Mousli, O. Filhol, 2004, Annals of the New York Academy of Sciences.

A Site ofTyrosine Phosphorylation intheC Terminus ofthe Epidermal GrowthFactor Receptor IsRequired ToActivate Phospholipase C

S. Rhee, O. Filhol, C. Cochet, 1992 .

Coexpression of both alpha and beta subunits is required for assembly of regulated casein kinase II.

E. Chambaz, P. Wedegaertner, O. Filhol, 1991, Biochemistry.

The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma

G. Pagès, J. Quesada, J. Ferrero, 2018, British Journal of Cancer.

DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons

P. Greengard, A. Nairn, J. Girault, 2015, Nature Communications.

Cytoplasmic and nuclear distribution of casein kinase II: characterization of the enzyme uptake by bovine adrenocortical nuclear preparation.

E. Chambaz, O. Filhol, C. Cochet, 1990, Biochemistry.

FRET-based screening assay using small-molecule photoluminescent probes in lysate of cells overexpressing RFP-fused protein kinases.

F. Herberg, A. Prinz, O. Filhol, 2015, Analytical biochemistry.

Protein kinase CK2 in breast cancer: the CK2β regulatory subunit takes center stage in epithelial plasticity

O. Filhol, C. Cochet, Y. Wallez, 2015, Cellular and Molecular Life Sciences.

Protein kinase CK2 contributes to placental development: physiological and pathological implications

N. Alfaidy, Daniel Vaiman, O. Filhol, 2019, Journal of Molecular Medicine.

Engrailed homeoprotein secretion is a regulated process.

A. Prochiantz, A. Joliot, A. Maizel, 2002, Development.

CK2 accumulation at the axon initial segment depends on sodium channel Nav1

H. Vacher, Christophe Leterrier, B. Dargent, 2014, FEBS letters.

Highlighting protein kinase CK2 movement in living cells

D. Grunwald, C. Souchier, Nathalie Theis-Febvre, 2005, Molecular and Cellular Biochemistry.

The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma

G. Pagès, J. Quesada, J. Ferrero, 2018, British Journal of Cancer.

In vitro and in vivo assays of protein kinase CK2 activity.

V. Moucadel, R. Prudent, O. Filhol, 2010, Methods in enzymology.

Structure–function analysis of the beta regulatory subunit of protein kinase CK2 by targeting embryonic stem cell

T. Buchou, R. Prudent, O. Filhol, 2011, Molecular and Cellular Biochemistry.

Microenvironment of metastatic site reveals key predictors of PD-1 blockade response in renal cell carcinoma

Catia Pesquita, M. Stares, J. Long, 2023, bioRxiv.

Spatial organization of the extracellular matrix regulates cell–cell junction positioning

H. Guillou, Qingzong Tseng, E. Duchemin-Pelletier, 2012, Proceedings of the National Academy of Sciences.

Casein kinase 2 inhibits the renaturation of complementary DNA strands mediated by p53 protein.

O. Filhol, C. Cochet, Edmond M. Chambaz, 1996, The Biochemical journal.

CIGB-300 anticancer peptide regulates the protein kinase CK2-dependent phosphoproteome

Osmany Guirola, Y. Perera, G. Padrón, 2020, Molecular and Cellular Biochemistry.

A new scaffold-free tumoroid model provides a robust preclinical tool to investigate invasion and drug response in Renal Cell Carcinoma

F. Chalmel, C. Battail, O. Filhol, 2023, Cell death & disease.

2-Aminothiazole derivatives as selective allosteric modulators of the protein kinase CK2. Part 2: Structure–based optimization and investigation of effects specific to the allosteric mode of action

I. Kufareva, O. Filhol, Weiguang Seetoh, 2020 .