Alexander J. A. Cobb

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AID Enzymatic Activity Is Inversely Proportional to the Size of Cytosine C5 Orbital Cloud

Svend K. Petersen-Mahrt, K. Schmitz, Gopinath Rangam, 2012, PloS one.

Targeting C-reactive protein for the treatment of cardiovascular disease

Steven V. Ley, Carol V. Robinson, Darren Thompson, 2006, Nature.

Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions.

S. Ley, Deborah A. Longbottom, Alexander J. A. Cobb, 2005, Organic & biomolecular chemistry.

Organocatalytic enantioselective construction of nitrocyclohexanes containing multiple chiral centres via a cascade reaction

K. Shankland, Alexander J. A. Cobb, S. Rajkumar, 2012 .

Organocatalytic domino reaction of cyanosulfones: access to complex cyclohexane systems with quaternary carbon centers.

K. Shankland, J. Goodman, Alexander J. A. Cobb, 2013, Organic letters.

Enantioselective Organocatalytic Synthesis of Bicyclic Resorcinols via an Intramolecular Friedel−Crafts‐Type 1,4‐Addition: Access to Cannabidiol Analogues

K. Shankland, Alexander J. A. Cobb, Nicholas R. Lees, 2021, Advanced synthesis & catalysis.

High potency of lipid conjugated TLR7 agonist requires nanoparticulate or liposomal formulation

K. Shankland, F. Greco, I. Hamley, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Emergent Glycerophospholipid Fluorescent Probes: Synthesis and Applications.

M. Segundo, Alexander J. A. Cobb, Eduarda M. P. Silva, 2019, Bioconjugate chemistry.

Asymmetric synthesis using catalysts containing multiple stereogenic centres and a trans-1,2-diaminocyclohexane core; reversal of predominant enantioselectivity upon N-alkylation

C. Marson, Alexander J. A. Cobb, 2005 .

Reversal of enantioselectivity using catalysts containing multiple stereogenic centres

C. Marson, Alexander J. A. Cobb, 2001 .

Synthesis and Antiviral Properties of Spirocyclic [1,2,3]‐Triazolooxazine Nucleosides

B. Neuman, K. Shankland, Matthew M. W. McLachlan, 2014, Chemistry.

Recent highlights in modified oligonucleotide chemistry.

Alexander J. A. Cobb, Alexander J A Cobb, 2007, Organic & biomolecular chemistry.

Mild and rapid method for the generation of ortho-(naphtho)quinone methide intermediates.

G. Varvounis, Alexander J. A. Cobb, Abdul kadar Shaikh, 2012, Organic letters.

5-Pyrrolidin-2-yltetrazole as an asymmetric organocatalyst for the addition of ketones to nitro-olefins.

S. Ley, Deborah A. Longbottom, Alexander J. A. Cobb, 2004, Chemical communications.

Enantioselective intramolecular michael addition of nitronates onto conjugated esters: access to cyclic gamma-amino acids with up to three stereocenters.

D. R. Nutt, Alexander J. A. Cobb, A. Chippindale, 2009, Journal of the American Chemical Society.

Syntheses and applications of enantiopure δ-amino acids and their precursors

Alexander J. A. Cobb, Ryan T. Stendall, 2018, Tetrahedron.

Asymmetric Organocatalytic Synthesis of Cyclopentane γ-Nitroketones

K. Shankland, Alexander J. A. Cobb, W. Al-ani, 2015, Synlett.

Asymmetric Organocatalysis and the Nitro Group Functionality

Alexander J. A. Cobb, A. Dell'isola, Lewis S. Aitken, 2013, Synthesis.

General Aspects of Organocatalytic Cyclizations

Alexander J. A. Cobb, 2011 .

Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts

Alexander J. A. Cobb, Laura A. Bryant, R. Fanelli, 2016, Beilstein journal of organic chemistry.

Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to δ(3)-amino acids.

K. Shankland, Alexander J. A. Cobb, Geoffrey D. Brown, 2015, Chemical communications.

Construction of functionalised medium rings by stereospecific expansions of 2,3-epoxy alcohols under mild conditions

C. Marson, Alexander J. A. Cobb, Afzal Khan, 2002 .

Synthesis of an intriguing steroidal constitutional isomer

K. Shankland, Alexander J. A. Cobb, A. Weymouth-Wilson, 2020, Tetrahedron Letters.

Asymmetric Phase-Transfer-CatalyzedSynthesis of Five-Membered Cyclic γ-Amino AcidPrecursors

K. Shankland, Alexander J. A. Cobb, S. Rajkumar, 2010 .

Aldol reaction of butane-2,3-diacetal protected methyl glycerate

Alexander J. A. Cobb, P. Heath, S. E. Fern, 2011 .

Organocatalytic Access to a cis-Cyclopentyl-γ-amino Acid: An Intriguing Model of Selectivity and Formation of a Stable 10/12-Helix from the Corresponding γ/α-Peptide.

K. Shankland, E. Rosta, R. Atkinson, 2019, Journal of the American Chemical Society.

5-Pyrrolidin-2-yltetrazole: A new, catalytic, more soluble alternative to proline in an organocatalytic asymmetric Mannich-type reaction

S. Ley, Alexander J. A. Cobb, D. M. Shaw, 2004 .

Synthesis and antiviral activity of novel spirocyclic nucleosides

B. Neuman, K. Shankland, Christin Müller, 2018 .

Organocatalysis with Proline Derivatives. Improved Catalysts for the Asymmetric Mannich, Nitro-Michael and Aldol Reactions.

S. Ley, Deborah A. Longbottom, Alexander J. A. Cobb, 2005 .

Targeted Activation of Toll-Like Receptors: Conjugation of a Toll-Like Receptor 7 Agonist to a Monoclonal Antibody Maintains Antigen Binding and Specificity.

F. Greco, A. Edwards, Alexander J. A. Cobb, 2015, Bioconjugate chemistry.

Highly Enantioselective, Organocatalytic and Scalable Synthesis of a rare cis-cis-Tricyclic Diterpenoid.

K. Shankland, Alexander J. A. Cobb, A. Weymouth-Wilson, 2020, Chemistry.

Trapping of palindromic ligands within native transthyretin prevents amyloid formation

C. Robinson, J. Mitchell, S. Ley, 2010, Proceedings of the National Academy of Sciences.

Organocatalytic Enantioselective Construction of Nitrocyclohexanes Containing Multiple Chiral Centers via a Cascade Reaction.

K. Shankland, Alexander J. A. Cobb, S. Rajkumar, 2012 .

Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to δ(3)-amino acids.

K. Shankland, Alexander J. A. Cobb, Geoffrey D. Brown, 2015, Chemical communications.