S. Napper

发表

Kinome analysis of Toll-like receptor signaling in bovine monocytes

L. Babiuk, A. Potter, R. Arsenault, 2009, Journal of receptor and signal transduction research.

EPIphany—A Platform for Analysis and Visualization of Peptide Immunoarray Data

A. Kusalik, P. Griebel, S. Napper, 2021, Frontiers in Bioinformatics.

The PhoQ-Activating Potential of Antimicrobial Peptides Contributes to Antimicrobial Efficacy and Is Predictive of the Induction of Bacterial Resistance

J. Kindrachuk, S. Napper, C. Reiman, 2007, Antimicrobial Agents and Chemotherapy.

Inflammatory Cytokines IL-32 and IL-17 Have Common Signaling Intermediates despite Differential Dependence on TNF-Receptor 1

H. El-Gabalawy, N. Mookherjee, R. Arsenault, 2011, The Journal of Immunology.

Divergent Immune Responses to Mycobacterium avium subsp. paratuberculosis Infection Correlate with Kinome Responses at the Site of Intestinal Infection

B. Trost, A. Potter, A. Kusalik, 2013, Infection and Immunity.

Induction of tissue- and stressor-specific kinomic responses in chickens exposed to hot and cold stresses.

B. Trost, A. Kusalik, P. Shand, 2015, Poultry science.

Human cathelicidin LL‐37 and its derivative IG‐19 regulate interleukin‐32‐induced inflammation

N. Mookherjee, S. Napper, K. Choi, 2014, Immunology.

Ibrutinib as a potential therapeutic option for HER2 overexpressing breast cancer – the role of STAT3 and p21

M. Sakharkar, S. Napper, C. Prabaharan, 2019, Investigational New Drugs.

From Beef to Bees: High-Throughput Kinome Analysis to Understand Host Responses of Livestock Species to Infectious Diseases and Industry-Associated Stress

A. Kusalik, S. Napper, Antonio Facciuolo, 2020, Frontiers in Immunology.

Development of Species‐ and Process‐Specific Peptide Kinome Arrays with Priority Application to Investigations of Infectious Disease

B. Trost, A. Kusalik, R. Arsenault, 2015 .

Peptide Arrays for Kinome Analysis of Livestock Species

B. Trost, A. Kusalik, R. Arsenault, 2014, Front. Vet. Sci..

Molecular characterization of breast cancer cell lines through multiple omic approaches

Frederick S. Vizeacoumar, Franco J. Vizeacoumar, F. Vizeacoumar, 2017, Breast Cancer Research.

A Bovine Enteric Mycobacterium Infection Model to Analyze Parenteral Vaccine-Induced Mucosal Immunity and Accelerate Vaccine Discovery

R. Hancock, A. Potter, V. Gerdts, 2020, Frontiers in Immunology.

Immunotherapy for prion diseases: opportunities and obstacles.

N. Cashman, S. Napper, Li Li, 2010, Immunotherapy.

Mutation of serine-46 to aspartate in the histidine-containing protein of Escherichia coli mimics the inactivation by phosphorylation of serine-46 in HPrs from gram-positive bacteria.

L. Delbaere, J. Quail, J. Anderson, 1996, Biochemistry.

Conservation of kinase-phosphorylation site pairings: Evidence for an evolutionarily dynamic phosphoproteome

B. Trost, S. Napper, Megan Mcdonald, 2018, PloS one.

Safety, specificity and immunogenicity of a PrPSc-specific prion vaccine based on the YYR disease specific epitope

A. Potter, Jeremy S. Lee, C. Madampage, 2014, Prion.

Methods and Protocols for Developing Prion Vaccines.

S. Napper, Ryan Taschuk, K. Marciniuk, 2016, Methods in molecular biology.

Induction of PrPSc-specific systemic and mucosal immune responses in white-tailed deer with an oral vaccine for chronic wasting disease

A. Potter, S. Tikoo, N. Cashman, 2017, Prion.

Computational Analysis of the Predicted Evolutionary Conservation of Human Phosphorylation Sites

B. Trost, A. Kusalik, S. Napper, 2016, PloS one.

TNF-Receptor 1 despite Differential Dependence on Have Common Signaling Intermediates Inflammatory Cytokines IL-32 and IL-17

H. El-Gabalawy, N. Mookherjee, R. Arsenault, 2011 .

Signaling differences in peripheral blood mononuclear cells of high and low vaccine responders prior to, and following, vaccination in piglets

A. Kusalik, G. Plastow, S. Napper, 2022, Vaccine: X.

Plasma Cytokines and Birth Weight as Biomarkers of Vaccine-Induced Humoral Responses in Piglets

P. Griebel, S. Napper, Antonio Facciuolo, 2022, Frontiers in Veterinary Science.

Therapeutic vaccines for amyotrophic lateral sclerosis directed against disease specific epitopes of superoxide dismutase 1.

N. Cashman, S. Napper, M. Yousefi, 2019, Vaccine.

TLR9 Signaling Failure Renders Peyer’s Patch Regulatory B Cells Unresponsive to Stimulation with CpG Oligodeoxynucleotides

L. Babiuk, A. Potter, G. Mutwiri, 2010, Journal of Innate Immunity.

In vitro neutralization of prions with PrPSc-specific antibodies

A. Potter, N. Cashman, P. Griebel, 2015, Prion.

Binding of bovine T194A PrPC by PrPSc-specific antibodies

A. Potter, Jeremy S. Lee, C. Madampage, 2013 .

Binding of bovine T194A PrP(C) by PrP(Sc)-specific antibodies: potential implications for immunotherapy of familial prion diseases.

A. Potter, Jeremy S. Lee, C. Madampage, 2013, Prion.

Marked Differences in Mucosal Immune Responses Induced in Ileal versus Jejunal Peyer’s Patches to Mycobacterium avium subsp. paratuberculosis Secreted Proteins following Targeted Enteric Infection in Young Calves

L. Mutharia, P. Griebel, S. Napper, 2016, PloS one.

Stability, toxicity and biological activity of retro, inversed and retro‐inversed glucagon isomers

B. Krasniqi, Jeremy S. Lee, S. Napper, 2012, Journal of peptide science : an official publication of the European Peptide Society.

Stability,toxicityandbiologicalactivityofretro, inversed and retro-inversed glucagon isomers BesnikKrasniqi, a ErinScruten, b JaretPiller, a JeremyLee a andScottNapper a,b *

S. Napper, 2012 .

Retro-inversion enhances the adjuvant and CpG co-adjuvant activity of host defence peptide Bac2A.

L. Babiuk, A. Potter, J. Kindrachuk, 2010, Vaccine.

Accelerated onset of chronic wasting disease in elk (Cervus canadensis) vaccinated with a PrPSc-specific vaccine and housed in a prion contaminated environment.

A. Potter, N. Cashman, Mary E. Wood, 2018, Vaccine.

PrPSc-specific antibodies do not induce prion disease or misfolding of PrPC in highly susceptible Tga20 mice

A. Potter, N. Cashman, S. Napper, 2013, Prion.

From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis

A. Potter, R. Arsenault, P. Griebel, 2014, Veterinary Research.

Stability, toxicity, and biological activity of host defense peptide BMAP28 and its inversed and retro‐inversed isomers

L. Babiuk, A. Potter, S. Attah-poku, 2011, Biopolymers.

Overexpression of l-Isoaspartate O-Methyltransferase in Escherichia coli Increases Heat Shock Survival by a Mechanism Independent of Methyltransferase Activity*

S. Attah-poku, J. Kindrachuk, S. Napper, 2003, Journal of Biological Chemistry.

The Influence of Protein Structure on the Products Emerging from Succinimide Hydrolysis*

J. Kindrachuk, S. Napper, F. Georges, 2002, The Journal of Biological Chemistry.

The Aspartyl Replacement of the Active Site Histidine in Histidine-containing Protein, HPr, of the Escherichia coliPhosphoenolpyruvate:Sugar Phosphotransferase System Can Accept and Donate a Phosphoryl Group

L. Delbaere, E. Waygood, S. Napper, 1999, The Journal of Biological Chemistry.

Kinome Analysis to Define Mechanisms of Adjuvant Action: PCEP Induces Unique Signaling at the Injection Site and Lymph Nodes

G. Mutwiri, S. Napper, E. Scruten, 2022, Vaccines.

Salmonella enterica Typhimurium infection causes metabolic changes in chicken muscle involving AMPK, fatty acid and insulin/mTOR signaling

M. Kogut, R. Arsenault, S. Napper, 2013, Veterinary Research.

Mechanism for the induction of cell death in ONS-76 medulloblastoma cells by Zhangfei/CREB-ZF

V. Misra, N. Rapin, S. Napper, 2012, Journal of Neuro-Oncology.

Kinome profiling of peripheral blood mononuclear cells collected prior to vaccination reveals biomarkers and potential mechanisms of vaccine unresponsiveness in pigs

A. Kusalik, G. Plastow, P. Griebel, 2020, Scientific Reports.

High-resolution analysis of long-term serum antibodies in humans following convalescence of SARS-CoV-2 infection

A. Kusalik, V. Gerdts, D. Falzarano, 2022, Scientific Reports.

Offspring affected with in utero Zika virus infection retain molecular footprints in the bone marrow and blood cells

S. Napper, Ivan Trus, U. Karniychuk, 2022, Emerging microbes & infections.

Relationship Between Conformation and Antiviral Activity -IV. 5-Ethyl-2′-Deoxyurldine and 5-Ethyl-2′-Deoxycytidine +

K. C. Brown, L. Delbaere, S. Napper, 1997 .

Investigation of the physiological, behavioral, and biochemical responses of cattle to restraint stress.

J. Stookey, R. Arsenault, P. Griebel, 2016, Journal of animal science.

Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota

M. Surette, Bo Li, A. Pierro, 2017, Microbiome.

Lambda display phage as a mucosal vaccine delivery vehicle for peptide antigens.

P. Griebel, S. Napper, P. González-Cano, 2017, Vaccine.

5‐Ethyl‐2'‐deoxycytidine, C11H17N3O4

V. S. Gupta, L. Delbaere, S. Napper, 1995 .

Peptide arrays for kinome analysis: New opportunities and remaining challenges

Philip Griebel, Scott Napper, Ryan Arsenault, 2011, Proteomics.

Technological advances for interrogating the human kinome.

Anthony Kusalik, Brett Trost, Scott Napper, 2017, Biochemical Society Transactions.

In Vitro Infection of Bovine Monocytes with Mycoplasma bovis Delays Apoptosis and Suppresses Production of Gamma Interferon and Tumor Necrosis Factor Alpha but Not Interleukin-10

S. Napper, E. Scruten, J. Perez-Casal, 2013, Infection and Immunity.

Alpha but Not Interleukin-10 Interferon and Tumor Necrosis Factor Suppresses Production of Gamma Mycoplasma bovis Delays Apoptosis and Infection of Bovine Monocytes with In Vitro

S. Napper, E. Scruten, J. Perez-Casal, 2013 .

Effect of BMAP-28 Antimicrobial Peptides on Leishmania major Promastigote and Amastigote Growth: Role of Leishmanolysin in Parasite Survival

W. Robert McMaster, Håvard Jenssen, Scott Napper, 2011, PLoS neglected tropical diseases.

Kinome Analysis of Honeybee (Apis mellifera L.) Dark-Eyed Pupae Identifies Biomarkers and Mechanisms of Tolerance to Varroa Mite Infestation

A. Kusalik, A. Robertson, P. Griebel, 2020, Scientific Reports.

Identification of developmentally-specific kinotypes and mechanisms of Varroa mite resistance through whole-organism, kinome analysis of honeybee

Anthony Kusalik, Philip Griebel, Brett Trost, 2014, Front. Genet..

EphB Receptors Trigger Akt Activation and Suppress Fas Receptor-Induced Apoptosis in Malignant T Lymphocytes

J. Xiang, A. Weng, A. Freywald, 2011, The Journal of Immunology.

Models and Methods to Investigate Acute Stress Responses in Cattle

R. Arsenault, P. Griebel, S. Napper, 2015, Animals : an open access journal from MDPI.

Molecular characterization of breast cancer cell lines through multiple omic approaches

F. Vizeacoumar, F. Vizeacoumar, S. Napper, 2017, Breast cancer research : BCR.

Kinotypes: stable species- and individual-specific profiles of cellular kinase activity

B. Trost, A. Kusalik, J. Kindrachuk, 2013, BMC Genomics.

PIIKA 2: An Expanded, Web-Based Platform for Analysis of Kinome Microarray Data

Anthony Kusalik, Brett Trost, Scott Napper, 2013, PloS one.

DAPPLE: a pipeline for the homology-based prediction of phosphorylation sites

Anthony J. Kusalik, Philip Griebel, Brett Trost, 2013, Bioinform..

A Systematic Approach for Analysis of Peptide Array Kinome Data

B. Trost, A. Kusalik, R. Arsenault, 2012, Science Signaling.

Genome to Kinome: Species-Specific Peptide Arrays for Kinome Analysis

Scott Napper, Lorne A. Babiuk, Ryan Arsenault, 2009, Science Signaling.

Kinotypes: stable species- and individual-specific profiles of cellular kinase activity

B. Trost, A. Kusalik, J. Kindrachuk, 2013, BMC Genomics.

Altered Toll-Like Receptor 9 Signaling in Mycobacterium avium subsp. paratuberculosis-Infected Bovine Monocytes Reveals Potential Therapeutic Targets

A. Potter, A. Kusalik, R. Arsenault, 2012, Infection and Immunity.

Mycobacterium avium subsp. paratuberculosis Inhibits Gamma Interferon-Induced Signaling in Bovine Monocytes: Insights into the Cellular Mechanisms of Johne's Disease

A. Kusalik, R. Arsenault, P. Griebel, 2012, Infection and Immunity.

Systems Kinomics Demonstrates Congo Basin Monkeypox Virus Infection Selectively Modulates Host Cell Signaling Responses as Compared to West African Monkeypox Virus

P. Jahrling, B. Trost, A. Kusalik, 2011, Molecular & Cellular Proteomics.

Phosphoproteome and Kinome Analysis: Unique Perspectives on the Same Problem

J. Kindrachuk, Shakiba Jalal, S. Napper, 2007 .

Regional Dichotomy in Enteric Mucosal Immune Responses to a Persistent Mycobacterium avium ssp. paratuberculosis Infection

R. Hancock, A. Potter, V. Gerdts, 2020, Frontiers in Immunology.

Mucosal changes in a long-term bovine intestinal segment model following removal of ingesta and microflora

A. Potter, L. Guan, C. Charavaryamath, 2011, Gut microbes.

BRK phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential

G. Hattem, K. Lukong, M. Washburn, 2019, Science Advances.

BRK Phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG and metastatic potential

Mihaela E. Sardiu, G. Hattem, K. Lukong, 2018 .

BRK Phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG and metastatic potential

Mihaela E. Sardiu, G. Hattem, K. Lukong, 2018, bioRxiv.

Phosphoproteomics Analysis Identifies Novel Candidate Substrates of the Nonreceptor Tyrosine Kinase, Src-related Kinase Lacking C-terminal Regulatory Tyrosine and N-terminal Myristoylation Sites (SRMS) *

K. Lukong, J. Reimand, M. Paczkowska, 2018, Molecular & Cellular Proteomics.

Host Responses to Persistent Mycobacterium avium Subspecies paratuberculosis Infection in Surgically Isolated Bovine Ileal Segments

A. Potter, C. Charavaryamath, P. Griebel, 2012, Clinical and Vaccine Immunology.

Carrier Protein Significantly Alters the Magnitude, Duration, and Type of Antibody Response to a Peptide Epitope from a Self-Protein

P. Griebel, S. Napper, Ryan Taschuk, 2015 .

Vaccines for prion diseases: a realistic goal?

S. Napper, H. Schatzl, 2023, Cell and Tissue Research.

Ebola Virus Modulates Transforming Growth Factor β Signaling and Cellular Markers of Mesenchyme-Like Transition in Hepatocytes

H. Feldmann, E. Postnikova, P. Jahrling, 2014, Journal of Virology.

Development of a multivalent, PrP(Sc)-specific prion vaccine through rational optimization of three disease-specific epitopes.

A. Potter, N. Cashman, P. Griebel, 2014, Vaccine.

Design and delivery of a cryptic PrP(C) epitope for induction of PrP(Sc)-specific antibody responses.

L. Babiuk, A. Potter, N. Cashman, 2010, Vaccine.

Ebola Virus Modulates Transforming Growth Factor-β Signaling and Cellular Markers of 1

Anthony, H. Feldmann, E. Postnikova, 2014 .

CHAPTER 6:Sample Preparation and Profiling: Probing the Kinome for Biomarkers and Therapeutic Targets: Peptide Arrays for Global Phosphorylation-Mediated Signal Transduction

J. Kindrachuk, S. Napper, 2013 .

Nucleic Acids Exert a Sequence-independent Cooperative Effect on Sequence-dependent Activation of Toll-like Receptor 9*

L. Babiuk, G. Mutwiri, N. Mookherjee, 2007, Journal of Biological Chemistry.

Strategies to Stimulate Innate Immunity for Designing Effective Vaccine Adjuvants

L. Babiuk, A. Potter, V. Gerdts, 2012 .

Transcriptional and translational expression patterns associated with immobilized growth of Campylobacter jejuni.

Eduardo N. Taboada, L. Babiuk, A. Potter, 2006, Microbiology.

DAPPLE 2: a Tool for the Homology-Based Prediction of Post-Translational Modification Sites.

Anthony Kusalik, Farhad Maleki, Brett Trost, 2016, Journal of proteome research.

Induction of functional interferon alpha and gamma responses during acute infection of cattle with non-cytopathic bovine viral diarrhea virus.

S. van Drunen Littel-van den Hurk, S. Napper, E. Scruten, 2016, Veterinary microbiology.

TargetsReveals Potential Therapeutic paratuberculosis-Infected Bovine Mycobacterium avium subsp. Altered Toll-Like Receptor 9 Signaling in

A. Potter, J. Arsenault, P. Griebel, 2014 .

EpIC: a rational pipeline for epitope immunogenicity characterization

Brett Trost, Scott Napper, Kristen Marciniuk, 2015, Bioinform..

Detection and Control of Prion Diseases in Food Animals

A. Potter, P. Griebel, S. Napper, 2012, ISRN veterinary science.

Evidence for Prion-Like Mechanisms in Several Neurodegenerative Diseases: Potential Implications for Immunotherapy

S. Napper, Ryan Taschuk, K. Marciniuk, 2013, Clinical & developmental immunology.

Structural investigation of a phosphorylation-catalyzed, isoaspartate-free, protein succinimide: crystallographic structure of post-succinimide His15Asp histidine-containing protein.

L. Prasad, L. Delbaere, S. Napper, 2008, Biochemistry.

Intramolecular rearrangements as a consequence of the dephosphorylation of phosphoaspartate residues in proteins

J. Stock, D. J. Webre, P. Wolanin, 2003, FEBS letters.

Nanopore analysis reveals differences in structural stability of ovine PrPC proteins corresponding to scrapie susceptible (VRQ) and resistance (ARR) genotypes

A. Potter, Jeremy S. Lee, C. Madampage, 2013, Prion.

Identification of Signaling Pathways Targeted by the Food Contaminant FB1: Transcriptome and Kinome Analysis of Samples from Pig Liver and Intestine.

H. Guillou, Y. Lippi, J. Bertrand-Michel, 2017, Molecular nutrition & food research.

Characterization of the Host Response to Pichinde Virus Infection in the Syrian Golden Hamster by Species-Specific Kinome Analysis*

P. Jahrling, B. Trost, A. Kusalik, 2015, Molecular & Cellular Proteomics.

Longitudinal analysis of SARS-CoV-2 reinfection reveals distinct kinetics and emergence of cross-neutralizing antibodies to variants of concern

V. Gerdts, D. Falzarano, A. Kroeker, 2023, Frontiers in Microbiology.

Identifying kinase targets of PPARγ in human breast cancer

M. Sakharkar, M. Essa, S. Napper, 2021, Journal of drug targeting.

Induction of ligand-specific PrPC signaling in human neuronal cells

A. Potter, A. Kusalik, R. Arsenault, 2012, Prion.

Identification of the Escherichia coli enzyme I binding site in histidine-containing protein, HPr, by the effects of mutagenesis.

L. Delbaere, E. Waygood, S. Brokx, 1999, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Substitution of Aspartate and Glutamate for Active Center Histidines in the Escherichia coliPhosphoenolpyruvate:Sugar Phosphotransferase System Maintain Phosphotransfer Potential*

L. Delbaere, E. Waygood, S. Brokx, 2001, The Journal of Biological Chemistry.

Attachment impacts cortisol awakening response in chronically depressed individuals

S. Napper, K. Marciniuk, G. Adams, 2020, Psychoneuroendocrinology.

Protein kinase C δ signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function

P. Sherman, S. Napper, N. Jones, 2017, Scientific Reports.

FRK inhibits breast cancer cell migration and invasion by suppressing epithelial-mesenchymal transition

Frederick S. Vizeacoumar, Franco J. Vizeacoumar, K. Lukong, 2017, Oncotarget.

CHIRAL SYNTHESIS OF (+)-8'-DEMETHYL ABSCISIC ACID

J. Quail, S. Napper, S. Abrams, 1996 .

Chiral Synthesis of (+)-8′-Demethyl Abscisic Acid.

J. Quail, S. Napper, S. Abrams, 1997 .

Immune Mechanisms and Therapeutic Potential of CpG Oligodeoxynucleotides

L. Babiuk, G. Mutwiri, S. Napper, 2006, International reviews of immunology.

Correction: PIIKA 2: An Expanded, Web-Based Platform for Analysis of Kinome Microarray Data

B. Trost, A. Kusalik, J. Kindrachuk, 2014, PLoS ONE.

Distinct, age-dependent TLR7/8 signaling responses in porcine gamma-delta T cells.

V. Gerdts, S. Napper, E. Scruten, 2023, Molecular immunology.

Case study: using sequence homology to identify putative phosphorylation sites in an evolutionarily distant species (honeybee)

Anthony J. Kusalik, Brett Trost, Scott Napper, 2015, Briefings Bioinform..

Oral vaccination as a potential strategy to manage chronic wasting disease in wild cervid populations

S. Napper, H. Schatzl, 2023, Frontiers in Immunology.

Activation and regulation of toll-like receptor 9: CpGs and beyond.

L. Babiuk, J. Kindrachuk, P. Griebel, 2008, Mini reviews in medicinal chemistry.