B. Lee

Hong-Hee Kim, S. Han, C. Yun, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Intradermal Immunization with Wall Teichoic Acid (WTA) Elicits and Augments an Anti-WTA IgG Response that Protects Mice from Methicillin-Resistant Staphylococcus aureus Infection Independent of Mannose-Binding Lectin Status

K. Kurokawa, E. Paul, B. Lee, 2013, PloS one.

PEI/NONOates-doped PLGA nanoparticles for eradicating methicillin-resistant Staphylococcus aureus biofilm in diabetic wounds via binding to the biofilm matrix.

Jin-Wook Yoo, Yunjin Jung, B. Lee, 2019, Materials science & engineering. C, Materials for biological applications.

CpG-DNA exerts antibacterial effects by protecting immune cells and producing bacteria-reactive antibodies

Sangkyu Park, Younghee Lee, H. Kwon, 2018, Scientific Reports.

The proPO-system: pros and cons for its role in invertebrate immunity.

L. Cerenius, K. Söderhäll, B. Lee, 2008, Trends in immunology.

Burkholderia gut symbiont modulates titer of specific juvenile hormone in the bean bug Riptortus pedestris.

T. Kotaki, T. Shinada, Jin-Wook Yoo, 2019, Developmental and comparative immunology.

The staphylococcal surface-glycopolymer wall teichoic acid (WTA) is crucial for complement activation and immunological defense against Staphylococcus aureus infection.

K. Kurokawa, B. Lee, Kazue Takahashi, 2016, Immunobiology.

Biochemical characterization of evasion from peptidoglycan recognition by Staphylococcus aureus D-alanylated wall teichoic acid in insect innate immunity.

K. Kurokawa, B. Lee, Lili Zheng, 2011, Developmental and comparative immunology.

Crystallization and preliminary X-ray crystallographic analysis of a highly specific serpin from the beetle Tenebrio molitor.

Hyun-Mi Kwon, S. Park, N. Ha, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purine Biosynthesis, Biofilm Formation, and Persistence of an Insect-Microbe Gut Symbiosis

Joon-Hee Lee, T. Fukatsu, Soo-Kyoung Kim, 2014, Applied and Environmental Microbiology.

Novel Bacterial Lipoprotein Structures Conserved in Low-GC Content Gram-positive Bacteria Are Recognized by Toll-like Receptor 2*

S. Akira, T. Saitoh, H. Nakayama, 2012, The Journal of Biological Chemistry.

Purification of properoxinectin, a myeloperoxidase homologue and its activation to a cell adhesion molecule.

Xionghui Lin, L. Cerenius, K. Söderhäll, 2007, Biochimica et biophysica acta.

The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2*

S. Akira, O. Takeuchi, H. Nakayama, 2009, Journal of Biological Chemistry.

Insecticidal activity of the metalloprotease AprA occurs through suppression of host cellular and humoral immunity

S. Kawabata, Jin-Wook Yoo, Yunjin Jung, 2018, Developmental and comparative immunology.

A Novel Role for an Insect Apolipoprotein (Apolipophorin III) in β-1,3-Glucan Pattern Recognition and Cellular Encapsulation Reactions 1

N. Ratcliffe, B. Lee, M. Whitten, 2004, The Journal of Immunology.

Recognition and Cellular Encapsulation-1 , 3-Glucan Pattern β ( Apolipophorin III ) in A Novel Role for an Insect Apolipoprotein

N. Ratcliffe, B. Lee, M. Whitten, 2004 .

A New Easter-type Serine Protease Cleaves a Masquerade-like Protein during Prophenoloxidase Activation in Holotrichia diomphalia Larvae*

So young Lee, Mi Hee Lee, M. Kim, 2002, The Journal of Biological Chemistry.

93-kDa Twin-domain Serine Protease Inhibitor (Serpin) Has a Regulatory Function on the Beetle Toll Proteolytic Signaling Cascade*

Joon-Hee Lee, Eunhye Kim, K. Kurokawa, 2011, Journal of Biological Chemistry.

Structural and Functional Characterization of a Highly Specific Serpin in the Insect Innate Immunity*

Eunhye Kim, Hyun-Mi Kwon, S. Park, 2010, The Journal of Biological Chemistry.

The molecular activation and regulation mechanisms of proteolytic Toll signaling cascade in insect innate immunity

M. Matsushita, K. Kurokawa, B. Lee, 2010 .

Three Pairs of Protease-Serpin Complexes Cooperatively Regulate the Insect Innate Immune Responses*

D. Gubb, Eunhye Kim, Ji-won Park, 2009, The Journal of Biological Chemistry.

Phenoloxidase Is an Important Component of the Defense against Aeromonas hydrophila Infection in a Crustacean, Pacifastacus leniusculus*

L. Cerenius, I. Söderhäll, K. Söderhäll, 2007, Journal of Biological Chemistry.

Enhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles

H. Moon, Jin-Wook Yoo, Min-Soo Kim, 2015, International journal of nanomedicine.

The symbiotic role of O-antigen of Burkholderia symbiont in association with host Riptortus pedestris.

B. Lee, J. Kim, H. Park, 2016, Developmental and comparative immunology.

Bacterial cell motility ofBurkholderia gut symbiont is required to colonize the insect gut

Y. Kikuchi, Jin-Wook Yoo, Jun Beom Lee, 2015, FEBS letters.

Symbiotic factors in Burkholderia essential for establishing an association with the bean bug, Riptortus pedestris.

B. Lee, J. Kim, 2015, Archives of insect biochemistry and physiology.

Purine biosynthesis , biofilm formation and persistence of an insect-microbe 3 gut symbiosis 4 5 Running title : Biofilm and purine synthesis in symbiosis 6 7

T. Fukatsu, Soo-Kyoung Kim, Chan-Hee Kim, 2014 .

Bacterial Cell Wall Synthesis Gene uppP Is Required for Burkholderia Colonization of the Stinkbug Gut

Ho Jin Lee, T. Fukatsu, N. Nikoh, 2013, Applied and Environmental Microbiology.

Structural evidence of α‐aminoacylated lipoproteins of Staphylococcus aureus

H. Nakayama, N. Dohmae, K. Kurokawa, 2011, The FEBS journal.

for Staphylococcus aureus B Is Exploited by Inhibitory Receptor Paired Ig-like Receptor

A. Aderem, D. Underhill, K. Kurokawa, 2012 .

Pleiotropic Roles of Polyglycerolphosphate Synthase of Lipoteichoic Acid in Growth of Staphylococcus aureus Cells

K. Kurokawa, K. Sekimizu, B. Lee, 2008, Journal of bacteriology.

Peptidoglycan activation of the proPO-system without a peptidoglycan receptor protein (PGRP)?

S. Kawabata, I. Söderhäll, K. Söderhäll, 2011, Developmental and comparative immunology.

Surface Glycopolymers Are Crucial for In Vitro Anti-Wall Teichoic Acid IgG-Mediated Complement Activation and Opsonophagocytosis of Staphylococcus aureus

P. Andersen, K. Kurokawa, A. Peschel, 2015, Infection and Immunity.

Inhibitory Role for d-Alanylation of Wall Teichoic Acid in Activation of Insect Toll Pathway by Peptidoglycan of Staphylococcus aureus

K. Kurokawa, K. Sekimizu, A. Shiratsuchi, 2010, The Journal of Immunology.

Auxiliary role for d‐alanylated wall teichoic acid in Toll‐like receptor 2‐mediated survival of Staphylococcus aureus in macrophages

K. Shimizu, K. Kurokawa, K. Sekimizu, 2010, Immunology.

An antimicrobial protein of the Riptortus pedestris salivary gland was cleaved by a virulence factor of Serratia marcescens

Jun Beom Lee, D. Ferrandon, B. Lee, 2017, Developmental and comparative immunology.

Purification and characterization of tenecin 4, a new anti-Gram-negative bacterial peptide, from the beetle Tenebrio molitor.

Ji-won Park, K. Kurokawa, Y. Jo, 2012, Developmental and comparative immunology.

Protease IV, a quorum sensing‐dependent protease of Pseudomonas aeruginosa modulates insect innate immunity

Joon-Hee Lee, Su-Jin Park, Soo-Kyoung Kim, 2014, Molecular microbiology.

Colon-targeted delivery of cyclosporine A using dual-functional Eudragit® FS30D/PLGA nanoparticles ameliorates murine experimental colitis

H. Moon, E. Im, Jin-Wook Yoo, 2018, International journal of nanomedicine.

Cell-mediated immunity in arthropods: hematopoiesis, coagulation, melanization and opsonization.

K. Söderhäll, B. Lee, P. Jiravanichpaisal, 2006, Immunobiology.

Proteolytic cascades and their involvement in invertebrate immunity.

S. Kawabata, L. Cerenius, K. Söderhäll, 2010, Trends in biochemical sciences.

Identification and properties of a receptor for the invertebrate cytokine astakine, involved in hematopoiesis.

Xionghui Lin, I. Söderhäll, K. Söderhäll, 2009, Experimental cell research.

Recent advances in the innate immunity of invertebrate animals.

S. Iwanaga, B. Lee, 2005, Journal of biochemistry and molecular biology.

Human Mannose-binding Lectin and l-Ficolin Function as Specific Pattern Recognition Proteins in the Lectin Activation Pathway of Complement*

T. Fujita, M. Matsushita, J. W. Park, 2004, Journal of Biological Chemistry.

Insect Gut Symbiont Susceptibility to Host Antimicrobial Peptides Caused by Alteration of the Bacterial Cell Envelope*

H. Nakayama, T. Fukatsu, L. Sturiale, 2015, The Journal of Biological Chemistry.

Crystal structure of a clip‐domain serine protease and functional roles of the clip domains

Nam-Chul Ha, Byung-Ha Oh, B. Oh, 2005, The EMBO journal.

A zymogen form of masquerade-like serine proteinase homologue is cleaved during pro-phenoloxidase activation by Ca2+ in coleopteran and Tenebrio molitor larvae.

M. Kim, S. Kawabata, J. W. Park, 2002, European journal of biochemistry.

A Synthetic Peptidoglycan Fragment as a Competitive Inhibitor of the Melanization Cascade*

K. Fukase, S. Kusumoto, K. Söderhäll, 2006, Journal of Biological Chemistry.

A Novel 40-kDa Protein Containing Six Repeats of an Epidermal Growth Factor-Like Domain Functions as a Pattern Recognition Protein for Lipopolysaccharide1

H. Brade, L. Brade, I. Söderhäll, 2006, The Journal of Immunology.

Crystal Structure of the Serine Protease Domain of Prophenoloxidase Activating Factor-I*

J. W. Park, N. Ha, B. Lee, 2007, Journal of Biological Chemistry.

A Novel 43-kDa Protein as a Negative Regulatory Component of Phenoloxidase-induced Melanin Synthesis*

I. Söderhäll, K. Söderhäll, J. W. Park, 2005, Journal of Biological Chemistry.

Characterization and Properties of a 1,3-β-d-Glucan Pattern Recognition Protein of Tenebrio molitor Larvae That Is Specifically Degraded by Serine Protease during Prophenoloxidase Activation*

S. Kawabata, K. Söderhäll, Rong Zhang, 2003, Journal of Biological Chemistry.

An 86 kDa diapause protein 1‐like protein is a component of early‐staged encapsulation‐relating proteins in coleopteran insect, Tenebrio molitor larvae 1

S. Natori, B. Lee, M. Cho, 1999, FEBS letters.

The pro‐phenoloxidase of coleopteran insect, Tenebrio molitor, larvae was activated during cell clump/cell adhesion of insect cellular defense reactions 1

S. Natori, B. Lee, M. Cho, 1999, FEBS letters.

Processing of an Antibacterial Peptide from Hemocyanin of the Freshwater Crayfish Pacifastacus leniusculus *

So young Lee, K. Söderhäll, B. Lee, 2003, The Journal of Biological Chemistry.

Genomic organization, sequence characterization and expression analysis of Tenebrio molitor apolipophorin-III in response to an intracellular pathogen, Listeria monocytogenes.

Y. Han, B. Patnaik, Y. Jo, 2014, Gene.

Clustering of peptidoglycan recognition protein-SA is required for sensing lysine-type peptidoglycan in insects

B. Oh, Ji-won Park, Su-jin Kim, 2007, Proceedings of the National Academy of Sciences.

Beetle immunity.

Ji-won Park, K. Kurokawa, N. Ha, 2010, Advances in experimental medicine and biology.

Protein for Lipopolysaccharide Domain Functions as a Pattern Recognition Factor-LikeRepeats of an Epidermal Growth A Novel 40-kDa Protein Containing Six Söderhäll

H. Brade, L. Brade, I. Söderhäll, 2006 .

A Novel Protein Acts as a Negative Regulator of Prophenoloxidase Activation and Melanization in the Freshwater Crayfish Pacifastacus leniusculus*

I. Söderhäll, K. Söderhäll, M. Novotný, 2009, Journal of Biological Chemistry.

An immune-responsive Serpin regulates the melanization cascade in Drosophila.

B. Lemaître, E. De Gregorio, Sung-jun Han, 2002, Developmental cell.

A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway

B. Lemaître, M. Poidevin, N. Buchon, 2009, Proceedings of the National Academy of Sciences.

Diversity of Innate Immune Recognition Mechanism for Bacterial Polymeric meso-Diaminopimelic Acid-type Peptidoglycan in Insects

Ji-won Park, H. Nakayama, N. Dohmae, 2010, The Journal of Biological Chemistry.

In silico designed Staphylococcus aureus B-cell multi-epitope vaccine did not elicit antibodies against target antigens suggesting multi-domain approach.

T. Bae, B. Lee, Xinrui Mao, 2022, Journal of immunological methods.

PhaR, a Negative Regulator of PhaP, Modulates the Colonization of a Burkholderia Gut Symbiont in the Midgut of the Host Insect, Riptortus pedestris

Y. Jo, B. Lee, H. Jang, 2017, Applied and Environmental Microbiology.

Burkholderia gut symbionts enhance the innate immunity of host Riptortus pedestris.

Jin-Wook Yoo, Jun Beom Lee, Chan-Hee Kim, 2015, Developmental and comparative immunology.

Understanding regulation of the host-mediated gut symbiont population and the symbiont-mediated host immunity in the Riptortus-Burkholderia symbiosis system.

T. Fukatsu, Y. Han, Jun Beom Lee, 2016, Developmental and comparative immunology.

Interactions between Mycoplasma pulmonis and immune systems in the mealworm beetle, Tenebrio molitor.

H. Yun, B. Lee, I. Lee, 2019, Insect biochemistry and molecular biology.

Expressed Sequence Tags (ESTs) analysis of Tenebrio molitor larvae

Y. Han, B. Patnaik, H. Hwang, 2013 .

Gene Expression in Gut Symbiotic Organ of Stinkbug Affected by Extracellular Bacterial Symbiont

T. Fukatsu, N. Nikoh, Y. Kikuchi, 2013, PloS one.

Polyester synthesis genes associated with stress resistance are involved in an insect–bacterium symbiosis

Y. Rhee, H. Nakayama, N. Dohmae, 2013, Proceedings of the National Academy of Sciences.

Environment-Mediated Accumulation of Diacyl Lipoproteins over Their Triacyl Counterparts in Staphylococcus aureus

H. Nakayama, N. Dohmae, K. Kurokawa, 2012, Journal of bacteriology.

Lipid moieties on lipoproteins of commensal and non-commensal staphylococci induce differential immune responses

O. Tichá, H. Nakayama, I. Bekeredjian-Ding, 2017, Nature Communications.

The role of phagocytosis in IL-8 production by human monocytes in response to lipoproteins on Staphylococcus aureus.

K. Kurokawa, B. Lee, H. Kim, 2011, Biochemical and biophysical research communications.

Interaction of psoralen-derivatlzed oligodeoxyribonucleoside methyiphosphonates with synthetic DNA containing a promoter for 11 RNA polymerase

P. Miller, B. Lee, K. Blake, 1988 .

Chapter Six - Insect Symbiosis and Immunity: The Bean Bug–Burkholderia Interaction as a Case Study

B. Lee, J. Kim, 2017 .

Gene structure, cDNA characterization and RNAi-based functional analysis of a myeloid differentiation factor 88 homolog in Tenebrio molitor larvae exposed to Staphylococcus aureus infection.

Y. Han, B. Patnaik, Y. Jo, 2014, Developmental and comparative immunology.

Cloning, Characterization and Effect of TmPGRP-LE Gene Silencing on Survival of Tenebrio Molitor against Listeria monocytogenes Infection

Y. Han, B. Patnaik, Y. Jo, 2013, International journal of molecular sciences.

Independent Recognition of Staphylococcus aureus by Two Receptors for Phagocytosis in Drosophila*

K. Sekimizu, A. Shiratsuchi, K. Sakurai, 2012, The Journal of Biological Chemistry.

Insect’s intestinal organ for symbiont sorting

Y. Kamagata, T. Fukatsu, N. Nikoh, 2015, Proceedings of the National Academy of Sciences.

The roles of antimicrobial peptide, rip‐thanatin, in the midgut of Riptortus pedestris

Y. Kikuchi, Y. Seo, B. Lee, 2018, Developmental and comparative immunology.

Purine biosynthesis-deficient Burkholderia mutants are incapable of symbiotic accommodation in the stinkbug

T. Fukatsu, N. Nikoh, Y. Kikuchi, 2013, The ISME Journal.

Identification and expression analysis of a novel R-type lectin from the coleopteran beetle, Tenebrio molitor.

Y. Han, B. Patnaik, Yong Seok Lee, 2013, Journal of invertebrate pathology.

Rapid Exchange of Bound ADP on the Staphylococcus aureus Replication Initiation Protein DnaA*

T. Takaki, K. Kurokawa, K. Sekimizu, 2009, The Journal of Biological Chemistry.

Glycoepitopes of Staphylococcal Wall Teichoic Acid Govern Complement-mediated Opsonophagocytosis via Human Serum Antibody and Mannose-binding Lectin*

M. Matsushita, K. Kurokawa, A. Peschel, 2013, The Journal of Biological Chemistry.

Structural basis for the recognition of lysozyme by MliC, a periplasmic lysozyme inhibitor in Gram-negative bacteria.

Ji-won Park, N. Ha, B. Lee, 2009, Biochemical and biophysical research communications.

An overview of the synergy and crosstalk between pentraxins and collectins/ficolins: their functional relevance in complement activation

P. Garred, B. Lee, Y. Ma, 2017, Experimental &Molecular Medicine.

Molecular Cloning, Sequence Characterization and Expression Analysis of a CD63 Homologue from the Coleopteran Beetle, Tenebrio molitor

Y. Han, B. Patnaik, Y. Jo, 2013, International journal of molecular sciences.

Interaction of cationic antimicrobial peptides with Mycoplasma pulmonis

K. Dybvig, B. Lee, I. Lee, 2013, FEBS letters.

Human Serum Mannose-binding Lectin Senses Wall Teichoic Acid Glycopolymer of Staphylococcus aureus, Which Is Restricted in Infancy*

M. Matsushita, J. Kwak, K. Kurokawa, 2010, The Journal of Biological Chemistry.

Mannose‐binding lectin without the aid of its associated serine proteases alters lipopolysaccharide‐mediated cytokine/chemokine secretion from human endothelial cells

J. Y. Kim, Sun‐mi Lee, B. Lee, 2007, Immunology.

Shuttle vectors derived from pN315 for study of essential genes in Staphylococcus aureus.

K. Kurokawa, K. Sekimizu, B. Lee, 2010, Biological & pharmaceutical bulletin.

A midgut lysate of the Riptortus pedestris has antibacterial activity against LPS O‐antigen‐deficient Burkholderia mutants

B. Lee, H. Jang, M. Seong, 2017, Developmental and comparative immunology.

Specific Midgut Region Controlling the Symbiont Population in an Insect-Microbe Gut Symbiotic Association

T. Fukatsu, Y. Kikuchi, Chan-Hee Kim, 2013, Applied and Environmental Microbiology.

A specified midgut region controlling the symbiont titer in an insect-microbe 3 gut symbiotic association 4 5 Running title : Insect midgut region with antimicrobial activity 6 7

T. Fukatsu, Y. Kikuchi, Chan-Hee Kim, 2013 .

Gut symbiotic bacteria stimulate insect growth and egg production by modulating hexamerin and vitellogenin gene expression

T. Fukatsu, Yu Matsuura, Y. Kikuchi, 2017, Developmental and comparative immunology.

Putative host-derived growth factor inducing colonization of Burkholderia gut symbiont in Riptortus insecticola insect.

B. Lee, J. Kim, Xinrui Mao, 2019, Developmental and comparative immunology.

A specific cathepsin-L-like protease purified from an insect midgut shows antibacterial activity against gut symbiotic bacteria.

Jin-Wook Yoo, Jun Beom Lee, Yunjin Jung, 2015, Developmental and comparative immunology.

Colon-targeted delivery of piceatannol enhances anti-colitic effects of the natural product: potential molecular mechanisms for therapeutic enhancement

Jin-Wook Yoo, Wooseong Kim, Yunjin Jung, 2015, Drug design, development and therapy.

Rat liver 10-formyltetrahydrofolate dehydrogenase, carbamoyl phosphate synthetase 1 and betaine homocysteine S-methytransferase were co-purified on Kunitz-type soybean trypsin inhibitor-coupled sepharose CL-4B.

Su-jin Kim, Kyungbaeg Roh, B. Lee, 2007, Journal of biochemistry and molecular biology.

Bridging effect of recombinant human mannose‐binding lectin in macrophage phagocytosis of Escherichia coli

A. Shiratsuchi, B. Lee, Ikuko Watanabe, 2008, Immunology.

Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity

C. Wolz, T. Stehle, P. Seeberger, 2018, Nature.

Human anti-peptidoglycan-IgG-mediated opsonophagocytosis is controlled by calcium mobilization in phorbol myristate acetate-treated U937 cells

K. Kurokawa, B. Lee, So-Young Rah, 2015, BMB reports.

The N2N3 domains of ClfA, FnbpA, and FnbpB in Staphylococcus aureus bind to human complement factor H, and their antibodies enhance the bactericidal capability of human blood.

M. Matsushita, T. Bae, Yunjin Jung, 2020, Journal of biochemistry.

Development of Combination Vaccine Conferring Optimal Protection against Six Pore-Forming Toxins of Staphylococcus aureus

T. Bae, Yunjin Jung, B. Lee, 2021, Infection and immunity.

S‐Nitrosoglutathione loaded poly(lactic‐co‐glycolic acid) microparticles for prolonged nitric oxide release and enhanced healing of methicillin‐resistant Staphylococcus aureus‐infected wounds

B. Jhun, Jin-Wook Yoo, J. Shin, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Synthesis and Biological Activity of Tetrameric Ribitol Phosphate Fragments of Staphylococcus aureus Wall Teichoic Acid.

B. Lee, Sang Ah Kim, T. Schmidt, 2018, Organic letters.

Burkholderia gut symbiont in the midgut of the host insect , Riptortus 4 pedestris 5 6 Running title : Role of PhaR in colonization of gut symbiont 7 8

Jun Beom Lee, Y. Jo, B. Lee, 2017 .

Specific Serum Ig Recognizing Staphylococcal Wall Teichoic Acid Induces Complement-Mediated Opsonophagocytosis against Staphylococcus aureus

M. Matsushita, K. Kurokawa, B. Lee, 2012, The Journal of Immunology.

Evaluation of Target Specificity of Antibacterial Agents Using Staphylococcus aureus ddlA Mutants and d-Cycloserine in a Silkworm Infection Model

K. Kurokawa, K. Sekimizu, H. Hamamoto, 2009, Antimicrobial Agents and Chemotherapy.

Depletion of autophagy-related genes ATG3 and ATG5 in Tenebrio molitor leads to decreased survivability against an intracellular pathogen, Listeria monocytogenes.

Y. Han, B. Patnaik, Y. Jo, 2015, Archives of insect biochemistry and physiology.

Soluble Host-Defense Lectins

M. Matsushita, B. Lee, D. Kilpatrick, 2012, Journal of Biomedicine and Biotechnology.