H. Schröder

R. Bohnensack, H. Schröder, G. Leyhausen, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Morphogenetically active scaffold for osteochondral repair (polyphosphate/alginate/N,O-carboxymethyl chitosan).

X. Wang, S. Wang, W. Müller, 2016, European cells & materials.

NanoSIMS: Insights into the Organization of the Proteinaceous Scaffold within Hexactinellid Sponge Spicules

Xiaohong Wang, Werner Müller, W. Müller, 2010, Chembiochem : a European journal of chemical biology.

Polyphosphate Reverses the Toxicity of the Quasi-Enzyme Bleomycin on Alveolar Endothelial Lung Cells In Vitro

W. Müller, H. Schröder, Xiaohong Wang, 2021, Cancers.

Polyphosphate: A Morphogenetically Active Implant Material Serving as Metabolic Fuel for Bone Regeneration.

W. Müller, H. Schröder, Xiaohong Wang, 2015, Macromolecular bioscience.

Biomimetic Alginate/Gelatin Cross-Linked Hydrogels Supplemented with Polyphosphate for Wound Healing Applications

W. Müller, H. Schröder, Xiaohong Wang, 2020, Molecules.

Polyphosphate, the physiological metabolic fuel for corneal cells: a potential biomaterial for ocular surface repair.

N. Pfeiffer, W. Müller, H. Schröder, 2019, Biomaterials science.

Biocalcite and Carbonic Acid Activators.

W. Müller, H. Schröder, Xiaohong Wang, 2017, Progress in molecular and subcellular biology.

Modulation of 2′‐5′oligoadenylate synthetase by environmental stress in the marine sponge Geodia cydonium

Werner Müller, M. Wiens, M. Kelve, 1997 .

Biosilica Electrically‐Insulating Layers by Soft Lithography‐Assisted Biomineralisation with Recombinant Silicatein

A. Polini, D. Pisignano, A. Camposeo, 2011, Advanced materials.

High biocompatibility and improved osteogenic potential of amorphous calcium carbonate/vaterite.

F. Wurm, W. Müller, H. Schröder, 2016, Journal of materials chemistry. B.

Alginate/silica composite hydrogel as a potential morphogenetically active scaffold for three-dimensional tissue engineering

B. Diehl-seifert, W. Müller, Q. Feng, 2013 .

Silicate modulates the cross‐talk between osteoblasts (SaOS‐2) and osteoclasts (RAW 264.7 cells): Inhibition of osteoclast growth and differentiation

B. Diehl-seifert, M. Wiens, H. Schröder, 2012, Journal of cellular biochemistry.

Kinetics of expression of prion protein in uninfected and scrapie‐infected N2a mouse neuroblastoma cells

M. Bachmann, H. Schröder, K. Pfeifer, 1993, Cell biochemistry and function.

Two-Armed Activation of Bone Mineral Deposition by the Flavones Baicalin and Baicalein, Encapsulated in Polyphosphate Microparticles.

W. Müller, M. Wiens, H. Schröder, 2017, The American journal of Chinese medicine.

Bio-vaterite formation by glycoproteins from freshwater pearls.

W. Müller, M. Wiens, D. Jacob, 2010, Micron.

Multifunctional polymer-derivatized γ-Fe2O3 nanocrystals as a methodology for the biomagnetic separation of recombinant His-tagged proteins

Muhammad Nawaz Tahir, Wolfgang Tremel, Werner E. G. Müller, 2008 .

Retinol encapsulated into amorphous Ca(2+) polyphosphate nanospheres acts synergistically in MC3T3-E1 cells.

B. Diehl-seifert, W. Müller, H. Schröder, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Nanoparticle-directed and ionically forced polyphosphate coacervation: a versatile and reversible core–shell system for drug delivery

I. Lieberwirth, W. Müller, H. Schröder, 2020, Scientific Reports.

Modulation of the Initial Mineralization Process of SaOS-2 Cells by Carbonic Anhydrase Activators and Polyphosphate

B. Diehl-seifert, W. Müller, Q. Feng, 2013, Calcified Tissue International.

Effect of Bacterial Infection on Stem Cell Pattern in Porifera

W. Müller, M. Wiens, I. Müller, 2009 .

Organized bacterial assemblies in manganese nodules: evidence for a role of S-layers in metal deposition

W. Müller, H. Schröder, Xiaohong Wang, 2009 .

Amorphous polyphosphate-hydroxyapatite: A morphogenetically active substrate for bone-related SaOS-2 cells in vitro.

Rafael Muñoz‐Espí, B. Diehl-seifert, W. Müller, 2016, Acta biomaterialia.

Functionalized Magnetic Nanoparticles for Selective Targeting of Cells

W. Tremel, J. Brieger, R. Zentel, 2009 .

Polyphosphate as a Bioactive and Biodegradable Implant Material: Induction of Bone Regeneration in Rats

B. Diehl-seifert, H. Schröder, Xiaohong Wang, 2016 .

Functional importance of coacervation to convert calcium polyphosphate nanoparticles into the physiologically active state

Werner Müller, I. Lieberwirth, H. Schröder, 2022, Materials today. Bio.

Molecular biomineralization: toward an understanding of the biogenic origin of polymetallic nodules, seamount crusts, and hydrothermal vents.

W. Müller, M. Wiens, H. Schröder, 2011, Progress in molecular and subcellular biology.

The morphogenetically active polymer, inorganic polyphosphate complexed with GdCl3, as an inducer of hydroxyapatite formation in vitro.

W. Müller, H. Schröder, Xiaohong Wang, 2016, Biochemical pharmacology.

Self-Healing Properties of Bioinspired Amorphous CaCO3/Polyphosphate-Supplemented Cement

Rafael Muñoz‐Espí, W. Müller, H. Schröder, 2020, Molecules.

Transformation of Construction Cement to a Self-Healing Hybrid Binder

Rafael Muñoz‐Espí, W. Müller, H. Schröder, 2019, International journal of molecular sciences.

A biomimetic approach to ameliorate dental hypersensitivity by amorphous polyphosphate microparticles.

W. Müller, Q. Feng, H. Schröder, 2016, Dental materials : official publication of the Academy of Dental Materials.

Polyphosphate as a donor of high-energy phosphate for the synthesis of ADP and ATP

W. Müller, Q. Feng, H. Schröder, 2017, Journal of Cell Science.

Restoration of Impaired Metabolic Energy Balance (ATP Pool) and Tube Formation Potential of Endothelial Cells under “high glucose”, Diabetic Conditions by the Bioinorganic Polymer Polyphosphate

W. Müller, Q. Feng, H. Schröder, 2017, Polymers.

Fabrication of a Silica Coating on Magnetic γ-Fe2O3 Nanoparticles by an Immobilized Enzyme

H. A. Therese, W. Tremel, P. Théato, 2008 .

Bifunctional dentifrice: Amorphous polyphosphate a regeneratively active sealant with potent anti-Streptococcus mutans activity.

W. Müller, Q. Feng, H. Schröder, 2017, Dental materials : official publication of the Academy of Dental Materials.

Biomineral Amorphous Lasers through Light‐Scattering Surfaces Assembled by Electrospun Fiber Templates

D. Pisignano, V. Fasano, M. Moffa, 2017, 1710.10160.

The Marine Sponge-Derived Inorganic Polymers, Biosilica and Polyphosphate, as Morphogenetically Active Matrices/Scaffolds for the Differentiation of Human Multipotent Stromal Cells: Potential Application in 3D Printing and Distraction Osteogenesis

V. Mailänder, B. Diehl-seifert, W. Müller, 2014, Marine drugs.

The enzyme carbonic anhydrase as an integral component of biogenic Ca-carbonate formation in sponge spicules☆

W. Müller, H. Schröder, M. Korzhev, 2013, FEBS open bio.

Biologizing titanium alloy implant material with morphogenetically active polyphosphate

G. Glasser, B. Diehl-seifert, W. Müller, 2015 .

Electrospun bioactive mats enriched with Ca-polyphosphate/retinol nanospheres as potential wound dressing

B. Diehl-seifert, W. Müller, H. Schröder, 2015, Biochemistry and biophysics reports.

Flashing light in sponges through their siliceous fiber network: A new strategy of “neuronal transmission” in animals

Werner Müller, W. Müller, H. Schröder, 2012 .

Molecular and biochemical approach for understanding the transition of amorphous to crystalline calcium phosphate deposits in human teeth.

Werner Müller, Rafael Muñoz‐Espí, H. Schröder, 2022, Dental materials : official publication of the Academy of Dental Materials.

Silica as a morphogenetically active inorganic polymer.

B. Diehl-seifert, W. Müller, H. Schröder, 2013, Biomaterials science.

Principles of Biofouling Protection in Marine Sponges: A Model for the Design of Novel Biomimetic and Bio-inspired Coatings in the Marine Environment?

C. Perry, Werner Müller, P. Proksch, 2013, Marine Biotechnology.

Evidence for biogenic processes during formation of ferromanganese crusts from the Pacific Ocean: implications of biologically induced mineralization.

W. Tremel, W. Müller, H. Schröder, 2009, Micron.

Inorganic Polyphosphate: Coacervate Formation and Functional Significance in Nanomedical Applications

Werner Müller, H. Schröder, Xiaohong Wang, 2022, International journal of nanomedicine.

Amorphous, Smart, and Bioinspired Polyphosphate Nano/Microparticles: A Biomaterial for Regeneration and Repair of Osteo-Articular Impairments In-Situ

Rafael Muñoz‐Espí, W. Müller, Q. Feng, 2018, International journal of molecular sciences.

Morphology of Sponge Spicules: Silicatein a Structural Protein for Bio‐Silica Formation

W. Tremel, U. Kolb, D. Pisignano, 2010 .

Enzyme-accelerated and structure-guided crystallization of calcium carbonate: role of the carbonic anhydrase in the homologous system.

G. Glasser, I. Lieberwirth, W. Müller, 2014, Acta biomaterialia.

Identification of a silicatein(-related) protease in the giant spicules of the deep-sea hexactinellid Monorhaphis chuni

W. Müller, H. Schröder, Xiaohong Wang, 2008, Journal of Experimental Biology.

Highly soluble multifunctional MnO nanoparticles for simultaneous optical and MRI imaging and cancer treatment using photodynamic therapy

W. Tremel, Thomas D. Schladt, K. Schneider, 2010 .

Bioengineering of the silica-polymerizing enzyme silicatein-alpha for a targeted application to hydroxyapatite.

F. Cui, T. Link, W. Müller, 2010, Acta biomaterialia.

Silicatein conjugation inside nanoconfined geometries through immobilized NTA-Ni(II) chelates.

W. Tremel, W. Müller, Mubarak Ali, 2013, Chemical communications.

A Novel Biomimetic Approach to Repair Enamel Cracks/Carious Damages and to Reseal Dentinal Tubules by Amorphous Polyphosphate

W. Müller, Q. Feng, H. Schröder, 2017, Polymers.

Differential in vitro Anti-HIV Activity of Natural Lignans

Werner Müller, H. Schröder, R. Steffen, 1990, Zeitschrift fur Naturforschung. C, Journal of biosciences.

ARTIFICIAL CARTILAGE BIOMATRIX FORMED OF HYALURONIC ACID AND MG 2 +-POLYPHOSPHATE

X. Wang, S. Wang, F. Wurm, 2016 .

Modulation of the Initial Mineralization Process of SaOS-2 Cells by Carbonic Anhydrase Activators and Polyphosphate

B. Diehl-seifert, W. Müller, Q. Feng, 2014, Calcified Tissue International.

3D printing of hybrid biomaterials for bone tissue engineering: Calcium-polyphosphate microparticles encapsulated by polycaprolactone.

W. Müller, H. Schröder, R. Steffen, 2017, Acta biomaterialia.

Nonenzymatic Transformation of Amorphous CaCO3 into Calcium Phosphate Mineral after Exposure to Sodium Phosphate in Vitro: Implications for in Vivo Hydroxyapatite Bone Formation

Werner Müller, Rafael Muñoz‐Espí, B. Diehl-seifert, 2015, Chembiochem : a European journal of chemical biology.

Uptake of polyphosphate microparticles in vitro (SaOS-2 and HUVEC cells) followed by an increase of the intracellular ATP pool size

W. Müller, Q. Feng, M. Wiens, 2017, PloS one.

Morphogenetic (Mucin Expression) as Well as Potential Anti-Corona Viral Activity of the Marine Secondary Metabolite Polyphosphate on A549 Cells

W. Müller, R. Tan, H. Schröder, 2020, Marine drugs.

Amplified morphogenetic and bone forming activity of amorphousversus crystalline calcium phosphate/polyphosphate.

Rafael Muñoz‐Espí, W. Müller, B. Al-Nawas, 2020, Acta biomaterialia.

Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca2+ level in osteoblasts (SaOS-2 cells) in vitro.

G. Glasser, I. Lieberwirth, B. Diehl-seifert, 2011, Acta biomaterialia.

Bioactive and biodegradable silica biomaterial for bone regeneration.

V. Mailänder, W. Müller, G. Mitov, 2014, Bone.

Au@MnO nanoflowers: hybrid nanocomposites for selective dual functionalization and imaging.

W. Tremel, P. Théato, Thomas D. Schladt, 2010, Angewandte Chemie.

Development of a morphogenetically active scaffold for three‐dimensional growth of bone cells: biosilica–alginate hydrogel for SaOS‐2 cell cultivation

Werner Müller, T. Link, W. Müller, 2015, Journal of tissue engineering and regenerative medicine.

An approach to a biomimetic bone scaffold: increased expression of BMP-2 and of osteoprotegerin in SaOS-2 cells grown onto silica-biologized 3D printed scaffolds

T. Link, W. Müller, Q. Feng, 2013 .

Fabrication of amorphous strontium polyphosphate microparticles that induce mineralization of bone cells in vitro and in vivo.

W. Müller, Q. Feng, H. Schröder, 2017, Acta biomaterialia.

Biofabrication of biosilica-glass by living organisms.

Wolfgang Tremel, Werner E G Müller, W. Tremel, 2008, Natural product reports.

Bioinspired Fabrication of Bio‐Silica‐Based Bone‐Substitution Materials

M. Wiens, H. Schröder, M. Korzhev, 2010 .

Characterization and osteogenic activity of a silicatein/biosilica-coated chitosan-graft-polycaprolactone.

W. Müller, M. Wiens, H. Schröder, 2014, Acta biomaterialia.

Biosilica-loaded poly(ϵ-caprolactone) nanofibers mats provide a morphogenetically active surface scaffold for the growth and mineralization of the osteoclast-related SaOS-2 cells.

T. Link, B. Diehl-seifert, W. Müller, 2014, Biotechnology journal.

The unique invention of the siliceous sponges: their enzymatically made bio-silica skeleton.

W. Müller, M. Wiens, H. Schröder, 2011, Progress in molecular and subcellular biology.

Osteogenic Potential of Biosilica on Human Osteoblast-Like (SaOS-2) Cells

H. Ushijima, G. Glasser, Werner Müller, 2010, Calcified Tissue International.

Sponge spicules as blueprints for the biofabrication of inorganic–organic composites and biomaterials

W. Tremel, F. Cui, W. Müller, 2009, Applied Microbiology and Biotechnology.

Amorphous Ca2+ polyphosphate nanoparticles regulate the ATP level in bone-like SaOS-2 cells

W. Müller, Q. Feng, H. Schröder, 2015, Journal of Cell Science.

Morphogenetically-Active Barrier Membrane for Guided Bone Regeneration, Based on Amorphous Polyphosphate

W. Müller, Xiaohong Wang, H. Schröder, 2017, Marine drugs.

Biosilica-based strategies for treatment of osteoporosis and other bone diseases.

W. Müller, M. Wiens, H. Schröder, 2011, Progress in molecular and subcellular biology.

Isolation and Characterization of a Mn(II)-Oxidizing Bacillus Strain from the Demosponge Suberites domuncula

W. Müller, M. Wiens, R. Batel, 2010, Marine drugs.

The Deep-Sea Natural Products, Biogenic Polyphosphate (Bio-PolyP) and Biogenic Silica (Bio-Silica), as Biomimetic Scaffolds for Bone Tissue Engineering: Fabrication of a Morphogenetically-Active Polymer

W. Müller, Q. Feng, H. Schröder, 2013, Marine drugs.

Caged Dexamethasone/Quercetin Nanoparticles, Formed of the Morphogenetic Active Inorganic Polyphosphate, are Strong Inducers of MUC5AC

W. Müller, H. Schröder, Xiaohong Wang, 2021, Marine drugs.

Potential biological role of laccase from the sponge Suberites domuncula as an antibacterial defense component.

T. Link, B. Diehl-seifert, W. Müller, 2015, Biochimica et biophysica acta.

A novel TiO2-assisted magnetic nanoparticle separator for treatment and inactivation of bacterial contaminants in aquatic systems

T. Link, W. Müller, R. Batel, 2014 .

Molecular cross-talk between sponge host and associated microbes

Werner Müller, M. Wiens, R. Batel, 2013, Phytochemistry Reviews.

Amorphous Polyphosphate and Ca‐Carbonate Nanoparticles Improve the Self‐Healing Properties of both Technical and Medical Cements

W. Müller, H. Schröder, Xiaohong Wang, 2020, Biotechnology journal.

Transformation of Amorphous Polyphosphate Nanoparticles into Coacervate Complexes: An Approach for the Encapsulation of Mesenchymal Stem Cells.

Gunnar Glasser, Ingo Lieberwirth, Meik Neufurth, 2018, Small.

Amorphous polyphosphate/amorphous calcium carbonate implant material with enhanced bone healing efficacy in a critical-size defect in rats

Q. Feng, H. Schröder, Xiaohong Wang, 2016, Biomedical materials.

The therapeutic potential of inorganic polyphosphate: A versatile physiological polymer to control coronavirus disease (COVID-19)

H. Schröder, Xiaohong Wang, M. Neufurth, 2021, Theranostics.

Electrospinning of Bioactive Wound-Healing Nets.

B. Diehl-seifert, W. Müller, H. Schröder, 2017, Progress in molecular and subcellular biology.

Enzymatically synthesized inorganic polymers as morphogenetically active bone scaffolds: application in regenerative medicine.

Werner E G Müller, W. Müller, H. Schröder, 2014, International review of cell and molecular biology.

Differential Expression of the Demosponge (Suberites domuncula) Carotenoid Oxygenases in Response to Light: Protection Mechanism Against the Self-Produced Toxic Protein (Suberitine)

M. Binder, W. Müller, J. von Lintig, 2012, Marine drugs.

Collagen-inducing biologization of prosthetic material for hernia repair: Polypropylene meshes coated with polyP/collagen.

W. Müller, H. Schröder, Xiaohong Wang, 2018, Journal of biomedical materials research. Part B, Applied biomaterials.

Manganese/polymetallic nodules: micro-structural characterization of exolithobiontic- and endolithobiontic microbial biofilms by scanning electron microscopy.

W. Müller, M. Wiens, H. Schröder, 2009, Micron.

Giant siliceous spicules from the deep-sea glass sponge Monorhaphis chuni.

W. Müller, H. Schröder, Xiaohong Wang, 2009, International review of cell and molecular biology.

Rebalancing β-Amyloid-Induced Decrease of ATP Level by Amorphous Nano/Micro Polyphosphate: Suppression of the Neurotoxic Effect of Amyloid β-Protein Fragment 25-35

Rafael Muñoz‐Espí, W. Müller, Q. Feng, 2017, International journal of molecular sciences.

Interaction of the retinoic acid signaling pathway with spicule formation in the marine sponge Suberites domuncula through activation of bone morphogenetic protein-1.

J. Kaandorp, M. Binder, W. Müller, 2011, Biochimica et biophysica acta.

Inducible ASABF-Type Antimicrobial Peptide from the Sponge Suberites domuncula: Microbicidal and Hemolytic Activity in Vitro and Toxic Effect on Molluscs in Vivo

W. Müller, M. Wiens, R. Batel, 2011, Marine drugs.

A cryptochrome‐based photosensory system in the siliceous sponge Suberites domuncula (Demospongiae)

D. Pisignano, Werner Müller, M. Wiens, 2010, The FEBS journal.

Bio-sintering processes in hexactinellid sponges: fusion of bio-silica in giant basal spicules from Monorhaphis chuni.

W. Müller, M. Wiens, H. Schröder, 2009, Journal of structural biology.

Luciferase a light source for the silica-based optical waveguides (spicules) in the demosponge Suberites domuncula

Y. Wang, D. Pisignano, M. Wiens, 2009, Cellular and Molecular Life Sciences.

Silicatein expression in the hexactinellid Crateromorpha meyeri: the lead marker gene restricted to siliceous sponges

Werner Müller, M. Wiens, H. Schröder, 2008, Cell and Tissue Research.

Silicateins, the major biosilica forming enzymes present in demosponges: protein analysis and phylogenetic relationship.

W. Müller, M. Wiens, H. Schröder, 2007, Gene.

Formation of giant spicules in the deep-sea hexactinellid Monorhaphis chuni (Schulze 1904): electron-microscopic and biochemical studies

W. Tremel, Werner Müller, H. Schröder, 2007, Cell and Tissue Research.

Evolutionary relationship of Porifera within the eukaryotes

Werner Müller, I. Müller, H. Schröder, 2006, Hydrobiologia.

Selenium affects biosilica formation in the demosponge Suberites domuncula

H. Ushijima, Werner Müller, I. Müller, 2005, The FEBS journal.

Stress to cadmium monitored by metallothionein gene induction in Paracentrotus lividus embryos

F. Zito, R. Russo, W. Müller, 2003, Cell stress & chaperones.

Annual cycles of apoptosis, DNA strand breaks, heat shock proteins, and metallothionen isoforms in dab (Limanda limanda): influences of natural factors and consequences for biological effect monitoring

H. Steinhart, U. Kammann, W. Wosniok, 2001, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Isoquercitrin and polyphosphate co-enhance mineralization of human osteoblast-like SaOS-2 cells via separate activation of two RUNX2 cofactors AFT6 and Ets1.

B. Diehl-seifert, W. Müller, Q. Feng, 2014, Biochemical pharmacology.

Biocalcite, a multifunctional inorganic polymer: Building block for calcareous sponge spicules and bioseed for the synthesis of calcium phosphate-based bone

W. Müller, H. Schröder, Xiaohong Wang, 2014, Beilstein journal of nanotechnology.

Biologization of Allogeneic Bone Grafts with Polyphosphate: A Route to a Biomimetic Periosteum

W. Müller, M. Wiens, T. Gerich, 2019, Advanced Functional Materials.

Inorganic polyphosphates: biologically active biopolymers for biomedical applications.

W. Müller, H. Schröder, Xiaohong Wang, 2013, Progress in molecular and subcellular biology.

Biosilicification of loricate choanoflagellate: organic composition of the nanotubular siliceous costal strips of Stephanoeca diplocostata

U. Kolb, W. Müller, E. Mugnaioli, 2010, Journal of Experimental Biology.

Synthesis of the Neurotoxin Quinolinic Acid in Apoptotic Tissue from Suberites domuncula: Cell Biological, Molecular Biological, and Chemical Analyses

S. Sudek, W. Müller, I. Müller, 2002, Marine Biotechnology.

Common Genetic Denominators for Ca++-Based Skeleton in Metazoa: Role of Osteoclast-Stimulating Factor and of Carbonic Anhydrase in a Calcareous Sponge

W. Müller, M. Wiens, H. Schröder, 2012, PloS one.

Cold stress defense in the freshwater sponge Lubomirskia baicalensis

H. Ushijima, E. Fattorusso, H. Schröder, 2007, The FEBS journal.

Ethylene Modulates Gene Expression in Cells of the Marine SpongeSuberites domuncula and Reduces the Degree of Apoptosis*

Werner Müller, W. Müller, I. Müller, 1999, The Journal of Biological Chemistry.

Silicateins, silicatein interactors and cellular interplay in sponge skeletogenesis: formation of glass fiber‐like spicules

M. Wiens, R. Batel, H. Schröder, 2012, The FEBS journal.

Metazoan circadian rhythm: toward an understanding of a light-based zeitgeber in sponges.

D. Pisignano, Xiaohong Wang, W. Müller, 2013, Integrative and comparative biology.

Flashing light signaling circuit in sponges: Endogenous light generation after tissue ablation in Suberites domuncula

D. Pisignano, M. Wiens, K. Jochum, 2010, Journal of cellular biochemistry.

Role of ATP during the initiation of microvascularization: acceleration of an autocrine sensing mechanism facilitating chemotaxis by inorganic polyphosphate.

W. Müller, H. Schröder, Xiaohong Wang, 2018, The Biochemical journal.

New Target Sites for Treatment of Osteoporosis.

W. Müller, H. Schröder, Xiaohong Wang, 2017, Progress in molecular and subcellular biology.

The largest Bio-Silica Structure on Earth: The Giant Basal Spicule from the Deep-Sea Glass Sponge Monorhaphis chuni

W. Müller, K. Jochum, H. Schröder, 2011, Evidence-based complementary and alternative medicine : eCAM.

Paleoclimate and evolution: emergence of sponges during the neoproterozoic.

W. Müller, H. Schröder, Xiaohong Wang, 2009, Progress in molecular and subcellular biology.

Dual effect of inorganic polymeric phosphate/polyphosphate on osteoblasts and osteoclasts in vitro

Werner Müller, B. Diehl-seifert, M. Wiens, 2012, Journal of tissue engineering and regenerative medicine.

The physiological polyphosphate as a healing biomaterial for chronic wounds: Crucial roles of its antibacterial and unique metabolic energy supplying properties

M. Zollo, Veronica Ferrucci, R. Tan, 2022, Journal of Materials Science & Technology.

The phosphoanhydride bond: one cornerstone of life

Xiaohong Wang, W. Müller, H. Schröder, 2019, The Biochemist.

W. Tremel, J. Kaandorp, W. Müller, 2007, Biomaterials.

Evidence for a biogenic, microorganismal origin of rock varnish from the Gangdese Belt of Tibet.

W. Müller, M. Wiens, K. Jochum, 2011, Micron.

Speciation of sponges in Baikal‐Tuva region: an outline

P. Wrede, W. Müller, H. Schröder, 2006 .

Optical properties of in-vitro biomineralised silica

A. Polini, R. Cingolani, D. Pisignano, 2012, Scientific Reports.

Silicateins--a novel paradigm in bioinorganic chemistry: enzymatic synthesis of inorganic polymeric silica.

D. Pisignano, W. Müller, H. Schröder, 2013, Chemistry.

The inorganic polymer, polyphosphate, blocks binding of SARS-CoV-2 spike protein to ACE2 receptor at physiological concentrations

I. Lieberwirth, W. Müller, H. Schröder, 2020, Biochemical Pharmacology.

Silicatein-Mediated Polycondensation of Orthosilicic Acid: Modeling of a Catalytic Mechanism Involving Ring Formation

Werner Müller, M. Wiens, H. Schröder, 2010, Silicon.

Giant basal spicule from the deep-sea glass sponge Monorhaphis chuni : synthesis of the largest bio-silica structure on Earth by silicatein

W. Müller, H. Schröder, Xiaohong Wang, 2009 .

The mitogen‐activated protein kinase p38 pathway is conserved in metazoans: Cloning and activation of p38 of the SAPK2 subfamily from the sponge Suberites domuncula *

Werner Müller, V. Gamulin, I. Müller, 2000, Biology of the cell.

An unexpected biomaterial against SARS-CoV-2: Bio-polyphosphate blocks binding of the viral spike to the cell receptor

W. Müller, H. Schröder, Xiaohong Wang, 2021, Materials Today.

Chapter 14 - Stress Response in Marine Sponges: Genes and Molecules Involved and Their use as Biomarkers

Werner Müller, M. Wiens, H. Schröder, 2000 .

Engineering a morphogenetically active hydrogel for bioprinting of bioartificial tissue derived from human osteoblast-like SaOS-2 cells.

Meik Neufurth, Werner E G Müller, Qingling Feng, 2014, Biomaterials.

The silicatein propeptide acts as inhibitor/modulator of self‐organization during spicule axial filament formation

Werner Müller, M. Wiens, H. Schröder, 2013, The FEBS journal.

Formation of siliceous spicules in the marine demosponge Suberites domuncula

W. Tremel, Werner Müller, H. Schröder, 2005, Cell and Tissue Research.

Effect of Bioglass on Growth and Biomineralization of SaOS-2 Cells in Hydrogel after 3D Cell Bioprinting

Werner E. G. Müller, Meik Neufurth, Qingling Feng, 2014, PloS one.

Mineralization of bone‐related SaOS‐2 cells under physiological hypoxic conditions

Werner Müller, B. Diehl-seifert, H. Schröder, 2016, The FEBS journal.

From nanoparticles via microtemplates and milliparticles to deep-sea nodules: biogenically driven mineral formation

Werner Müller, M. Wiens, R. Batel, 2012, Frontiers of Materials Science.

Superparamagnetic γ-Fe2O3 nanoparticles with tailored functionality for protein separation

H. A. Therese, W. Tremel, P. Théato, 2007 .

Enzymatic Synthesis and Surface Deposition of Tin Dioxide using Silicatein-α

W. Tremel, W. Müller, H. Schröder, 2011 .

Biosilica-based immobilization strategy for label-free OWLS sensors

K. Erdélyi, W. Müller, I. Szendrő, 2013 .

Biogenic inorganic polysilicates (biosilica): formation and biomedical applications.

W. Müller, M. Wiens, H. Schröder, 2013, Progress in molecular and subcellular biology.

The effect of toxicity of heavy metals contained in tailing sands on the organic carbon metabolic activity of soil microorganisms from different land use types in the karst region

Werner Müller, H. Schröder, W. Müller, 2015, Environmental Earth Sciences.

Safety and feasibility study of using polyphosphate (PolyP) in alveolar cleft repair: a pilot study

M. Helder, T. Forouzanfar, H. Schröder, 2021, Pilot and Feasibility Studies.

Inorganic polyphosphate induces accelerated tube formation of HUVEC endothelial cells

Rafael Muñoz‐Espí, W. Müller, Q. Feng, 2017, Cellular and Molecular Life Sciences.

Siliceous spicules in marine demosponges (example Suberites domuncula).

Wolfgang Tremel, Werner E G Müller, Carole C Perry, 2006, Micron.

Phylogenetic position of sponges in early metazoan evolution and bionic applications of siliceous sponge spicules

W. Müller, H. Schröder, Xiaohong Wang, 2007 .

Influence of CO_2/HCO_3^− on Microbial Communities in Two Karst Caves with High CO_2

Qiufang He, D. Yuan, H. Schröder, 2023, Journal of Earth Science.

Bio-inorganic Nanomaterials for Biomedical Applications (Bio-silica and Polyphosphate)

W. Müller, H. Schröder, Xiaohong Wang, 2014 .

Potentiation of the Cytotoxic Activity of Copper by Polyphosphate on Biofilm-Producing Bacteria: A Bioinspired Approach

W. Müller, H. Schröder, Xiaohong Wang, 2012, Marine drugs.

A new polyphosphate calcium material with morphogenetic activity

G. Glasser, Rafael Muñoz‐Espí, T. Link, 2015 .

Bioencapsulation of living bacteria (Escherichia coli) with poly(silicate) after transformation with silicatein-alpha gene.

W. Tremel, W. Müller, H. Schröder, 2008, Biomaterials.

Pathogen‐Mimicking MnO Nanoparticles for Selective Activation of the TLR9 Pathway and Imaging of Cancer Cells

H. A. Therese, W. Tremel, Werner Müller, 2009 .

From single molecules to nanoscopically structured functional materials: Au nanocrystal growth on TiO2 nanowires controlled by surface-bound silicatein.

H. A. Therese, W. Tremel, U. Kolb, 2006, Angewandte Chemie.

Acceleration of chronic wound healing by bio-inorganic polyphosphate: In vitro studies and first clinical applications

H. Schröder, Xiaohong Wang, M. Neufurth, 2022, Theranostics.

Enhancement of Wound Healing in Normal and Diabetic Mice by Topical Application of Amorphous Polyphosphate. Superior Effect of a Host–Guest Composite Material Composed of Collagen (Host) and Polyphosphate (Guest)

H. Ushijima, W. Müller, H. Schröder, 2017, Polymers.

Acceleration of Wound Healing through Amorphous Calcium Carbonate, Stabilized with High-Energy Polyphosphate

Werner Müller, B. Al-Nawas, R. Tan, 2023, Pharmaceutics.

A physiologically active interpenetrating collagen network that supports growth and migration of epidermal keratinocytes: zinc-polyP nanoparticles integrated into compressed collagen.

Rafael Muñoz‐Espí, W. Müller, R. Tan, 2020, Journal of materials chemistry. B.

Fabrication of a new physiological macroporous hybrid biomaterial/bioscaffold material based on polyphosphate and collagen by freeze-extraction.

W. Müller, Q. Feng, H. Schröder, 2017, Journal of materials chemistry. B.

A bio-imitating approach to fabricate an artificial matrix for cartilage tissue engineering using magnesium-polyphosphate and hyaluronic acid

W. Müller, H. Schröder, Xiaohong Wang, 2016 .

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor.

W. Müller, H. Schröder, Xiaohong Wang, 2020, Biomaterials science.

Materials and scaffolds in medical 3D printing and bioprinting in the context of bone regeneration.

Ibrahim T. Ozbolat, Martin Heller, Elisabeth Goetze, 2016, International journal of computerized dentistry.

Enzymatic production of biosilica glass using enzymes from sponges: basic aspects and application in nanobiotechnology (material sciences and medicine)

W. Tremel, Werner Müller, H. Schröder, 2007, Naturwissenschaften.

Silicateins , silicase and spicule-associated proteins : synthesis of demosponge silica skeleton and nanobiotechnological applications

W. Tremel, W. Müller, M. Wiens, 2017 .

Dissection of the structure-forming activity from the structure-guiding activity of silicatein: a biomimetic molecular approach to print optical fibers.

T. Link, W. Müller, H. Schröder, 2014, Journal of materials chemistry. B.

Formation of silicones mediated by the sponge enzyme silicatein-α.

W. Tremel, W. Müller, Anna Pietuch, 2010, Dalton transactions.

Chemical mimicry: hierarchical 1D TiO2@ZrO2 core-shell structures reminiscent of sponge spicules by the synergistic effect of silicatein-α and silintaphin-1.

W. Tremel, U. Kolb, P. Théato, 2011, Langmuir : the ACS journal of surfaces and colloids.

Formation of layered titania and zirconia catalysed by surface-bound silicatein.

W. Tremel, P. Théato, W. Müller, 2005, Chemical communications.

Biosilica aging: from enzyme-driven gelation via syneresis to chemical/biochemical hardening.

Lei Jiang, W. Müller, H. Schröder, 2013, Biochimica et biophysica acta.

Isolation of the silicatein-α interactor silintaphin-2 by a novel solid-phase pull-down assay.

Xiaohong Wang, T. Link, W. Müller, 2011, Biochemistry.

Hierarchical composition of the axial filament from spicules of the siliceous sponge Suberites domuncula: from biosilica-synthesizing nanofibrils to structure- and morphology-guiding triangular stems

U. Kolb, Werner Müller, E. Mugnaioli, 2012, Cell and Tissue Research.

Biosilica: Molecular Biology, Biochemistry and Function in Demosponges as well as its Applied Aspects for Tissue Engineering.

W. Müller, M. Wiens, H. Schröder, 2012, Advances in marine biology.

Silicatein: nanobiotechnological and biomedical applications.

W. Tremel, Xiaohong Wang, W. Müller, 2009, Progress in molecular and subcellular biology.

Double-stranded RNA polyinosinic-polycytidylic acid immobilized onto gamma-Fe2O3 nanoparticles by using a multifunctional polymeric linker.

W. Tremel, P. Théato, W. Müller, 2007, Small.

Self‐healing, an intrinsic property of biomineralization processes

Werner Müller, K. Jochum, H. Schröder, 2013, IUBMB life.

Distribution of Microfossils Within Polymetallic Nodules: Biogenic Clusters Within Manganese Layers

Werner Müller, M. Wiens, H. Schröder, 2012, Marine Biotechnology.

Amorphous Polyphosphate and Ca‐Carbonate Nanoparticles Improve the Self‐Healing Properties of both Technical and Medical Cements

W. Müller, H. Schröder, Xiaohong Wang, 2020 .

Utilization of metabolic energy in treatment of ocular surface disorders: polyphosphate as an energy source for corneal epithelial cell proliferation

N. Pfeiffer, W. Müller, M. Wiens, 2019, RSC advances.

The sponge silicatein-interacting protein silintaphin-2 blocks calcite formation of calcareous sponge spicules at the vaterite stage

D. Pisignano, W. Müller, H. Schröder, 2014 .

Enzyme‐Mediated Deposition of a TiO2 Coating onto Biofunctionalized WS2 Chalcogenide Nanotubes

H. A. Therese, W. Tremel, P. Théato, 2009 .

Ascorbyl palmitate–PCL fiber mats loaded with strontium polyphosphate nanoparticles for guided bone regeneration

Basma Ekram, H. Schröder, Xiaohong Wang, 2023, Polymer Bulletin.

Polyphosphate in Antiviral Protection: A Polyanionic Inorganic Polymer in the Fight Against Coronavirus SARS-CoV-2 Infection.

H. Schröder, Xiaohong Wang, M. Neufurth, 2022, Progress in molecular and subcellular biology.

Characterization and transcriptional regulation of rat glutamine tRNA-encoding genes: repression of tRNA(UUGGln) synthesis.

Y. Kuchino, W. Müller, H. Schröder, 1994, Gene.

Binding of Tat protein to TAR region of human immunodeficiency virus type 1 blocks TAR-mediated activation of (2'-5')oligoadenylate synthetase.

T. Okamoto, Werner Müller, W. Müller, 1990, AIDS research and human retroviruses.

Molecular cloning of a tyrosine kinase gene from the marine sponge Geodia cydonium: a new member belonging to the receptor tyrosine kinase class II family.

B. Rinkevich, W. Müller, V. Gamulin, 1994, Molecular membrane biology.

Identification of La ribonucleoproteins as a component of interchromatin granules.

M. Carmo-Fonseca, Werner Müller, H. Schröder, 1989, Experimental cell research.

gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: prevention by memantine.

J. Bormann, H. Ushijima, Werner Müller, 1992, European journal of pharmacology.

Expression of silicatein and collagen genes in the marine sponge Suberites domuncula is controlled by silicate and myotrophin.

H. Schröder, W. Müller, I. Müller, 2000, European journal of biochemistry.

The 2-5A system and HIV infection.

W. Müller, M. Kelve, H. Schröder, 1994, Progress in molecular and subcellular biology.

Applications of patient-specific 3D printing in medicine.

C. Vahl, P. Drees, W. Müller, 2016, International journal of computerized dentistry.

Cytoprotective effect of NMDA receptor antagonists on prion protein (PrionSc)-induced toxicity in rat cortical cell cultures.

H. Ushijima, W. Müller, H. Schröder, 1993, European journal of pharmacology.

Sarcophytolide: a new neuroprotective compound from the soft coral Sarcophyton glaucum.

W. Müller, W. Müller, H. Schröder, 1998, Toxicology.

Cryptochrome in Sponges

W. Müller, H. Schröder, Julia S. Markl, 2013, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Polyphosphate as a metabolic fuel in Metazoa: A foundational breakthrough invention for biomedical applications

H. Schröder, Xiaohong Wang, Werner E. G. Müller, 2016, Biotechnology journal.

Silicatein conjugation inside nanoconfined geometries through immobilized NTA-Ni(II) chelates.

W. Tremel, W. Müller, Mubarak Ali, 2013, Chemical communications.

Avarol restores the altered prostaglandin and leukotriene metabolism in monocytes infected with human immunodeficiency virus type 1.

W. Müller, M. Gašić, H. Schröder, 1991, Virus research.

Modulation of the nuclear-envelope nucleoside triphosphatase by poly(A)-rich mRNA and by microtubule protein.

W. Müller, H. Schröder, R. Zahn, 1982, European journal of biochemistry.

Upregulation of the 2-5A synthetase/RNase L antiviral pathway associated with chronic fatigue syndrome.

W. Müller, D. Strayer, H. Schröder, 1994, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Manganese/polymetallic nodules: micro-structural characterization of exolithobiontic- and endolithobiontic microbial biofilms by scanning electron microscopy.

W. Müller, M. Wiens, H. Schröder, 2009, Micron.

Induction of DNA Strand Breaks and Expression of HSP70 and GRP78 Homolog by Cadmium in the Marine Sponge Suberites domuncula

H. Steinhart, H. Schröder, W. Müller, 1999, Archives of environmental contamination and toxicology.

Contribution of sponge genes to unravel the genome of the hypothetical ancestor of Metazoa (Urmetazoa).

W. Müller, I. Müller, A. Skorokhod, 2001, Gene.

3D printing of hybrid biomaterials for bone tissue engineering: Calcium-polyphosphate microparticles encapsulated by polycaprolactone.

W. Müller, H. Schröder, R. Steffen, 2017, Acta biomaterialia.

Effect of dexamethasone on nuclear envelope nucleoside triphosphatase in fibroblasts 3T3 and melanoma cells MMLI.

P. Altmeyer, W. Müller, H. Schröder, 1984, The Journal of investigative dermatology.

Purification and characterization of a pore-forming protein from the marine sponge Tethya lyncurium.

W. Müller, A. Mangel, J. M. Leitão, 1992, European journal of biochemistry.

Silintaphin‐1 – interaction with silicatein during structure‐guiding bio‐silica formation

W. Müller, M. Wiens, K. Jochum, 2011, The FEBS journal.

Isolation and cloning of a C-type lectin from the hexactinellid sponge Aphrocallistes vastus: a putative aggregation factor.

S. Leys, W. Müller, I. Müller, 2001, Glycobiology.

Suppression of allograft rejection in the sponge Suberites domuncula by FK506 and expression of genes encoding FK506-binding proteins in allografts.

W. Müller, I. Müller, R. Batel, 2001, The Journal of experimental biology.

The Physiological Inorganic Polymers Biosilica and Polyphosphate as Key Drivers for Biomedical Materials in Regenerative Nanomedicine

H. Schröder, Xiaohong Wang, M. Neufurth, 2024, International journal of nanomedicine.

Biosilica aging: from enzyme-driven gelation via syneresis to chemical/biochemical hardening.

Lei Jiang, W. Müller, H. Schröder, 2013, Biochimica et biophysica acta.

Origin of the integrin-mediated signal transduction. Functional studies with cell cultures from the sponge Suberites domuncula.

W. Müller, R. Batel, H. Schröder, 1999, European journal of biochemistry.

Silicateins--a novel paradigm in bioinorganic chemistry: enzymatic synthesis of inorganic polymeric silica.

D. Pisignano, W. Müller, H. Schröder, 2013, Chemistry.

Transformation of Construction Cement to a Self-Healing Hybrid Binder

Rafael Muñoz‐Espí, W. Müller, H. Schröder, 2019, International journal of molecular sciences.

Artificial cartilage bio-matrix formed of hyaluronic acid and Mg2+-polyphosphate.

X. Wang, S. Wang, F. Wurm, 2016, European cells & materials.

Amorphous polyphosphate/amorphous calcium carbonate implant material with enhanced bone healing efficacy in a critical-size defect in rats

Q. Feng, H. Schröder, Xiaohong Wang, 2016, Biomedical materials.

Bio-silica and bio-polyphosphate: applications in biomedicine (bone formation).

H. Ushijima, W. Müller, M. Wiens, 2012, Current opinion in biotechnology.

Polyphosphate Nanoparticles: Balancing Energy Requirements in Tissue Regeneration Processes.

H. Schröder, Xiaohong Wang, M. Neufurth, 2024, Small.

Inorganic polyphosphate induces accelerated tube formation of HUVEC endothelial cells

Rafael Muñoz‐Espí, W. Müller, Q. Feng, 2017, Cellular and Molecular Life Sciences.

High biocompatibility and improved osteogenic potential of amorphous calcium carbonate/vaterite.

F. Wurm, W. Müller, H. Schröder, 2016, Journal of materials chemistry. B.

Flashing light signaling circuit in sponges: Endogenous light generation after tissue ablation in Suberites domuncula

D. Pisignano, M. Wiens, K. Jochum, 2010, Journal of cellular biochemistry.

Microfragmented Fat and Biphasic Calcium Phosphates for Alveolar Cleft Repair: Protocol for a Prospective, Nonblinded, First-in-Human Clinical Study

M. Helder, T. Forouzanfar, H. Schröder, 2024, JMIR research protocols.

Polyclonal antibodies to mannan from yeast also recognize the carbohydrate structure of gp120 of the AIDS virus: an approach to raise neutralizing antibodies to HIV-1 infection in vitro.

W. Müller, H. Schröder, G. Uhlenbruck, 1990, AIDS.