C. Dart

发表

Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets

Edward S A Humphries, C. Dart, 2015, Journal of biomolecular screening.

cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP).

C. Dart, O. Roberts, 2014, Biochemical Society transactions.

Evaluating Caveolin Interactions: Do Proteins Interact with the Caveolin Scaffolding Domain through a Widespread Aromatic Residue-Rich Motif?

D. Rigden, D. Byrne, C. Dart, 2012, PloS one.

Indirect Channel Regulation by Cholesterol: The Role of Caveolae and Caveolins in Regulating KATP Channel Function

C. Dart, 2012 .

SYMPOSIUM REVIEW: Lipid microdomains and the regulation of ion channel function

C. Dart, 2010, The Journal of physiology.

Lipid microdomains and k(+) channel compartmentation: detergent and non-detergent-based methods for the isolation and characterisation of cholesterol-enriched lipid rafts.

L. J. Sampson, C. Dart, Laura J. Sampson, 2008, Methods in molecular biology.

Exchange protein activated by cAMP (Epac) induces vascular relaxation by activating Ca2+‐sensitive K+ channels in rat mesenteric artery

C. Dart, R. Barrett-Jolley, O. Roberts, 2013, The Journal of physiology.

Hypoxia and metabolic inhibitors alter the intracellular ATP:ADP ratio and membrane potential in human coronary artery smooth muscle cells

C. Dart, T. Kamishima, J. Quayle, 2020, PeerJ.

Activation of ATP‐dependent K+ channels by hypoxia in smooth muscle cells isolated from the pig coronary artery.

N. Standen, C. Dart, 1995, The Journal of physiology.

Selective block of KATP channels: why the anti‐diabetic sulphonylureas and rosiglitazone have more in common than we thought

C. Dart, 2012, British journal of pharmacology.

Exchange protein activated by cAMP (Epac) mediates cAMP‐dependent but protein kinase A‐insensitive modulation of vascular ATP‐sensitive potassium channels

C. Dart, T. Kamishima, J. Quayle, 2009, The Journal of physiology.

Caveolae Localize Protein Kinase A Signaling to Arterial ATP-Sensitive Potassium Channels

N. Standen, L. J. Sampson, C. Dart, 2004, Circulation research.

Angiotensin II-activated protein kinase C targets caveolae to inhibit aortic ATP-sensitive potassium channels.

N. Standen, L. J. Sampson, C. Dart, 2007, Cardiovascular research.

Adenosine Activates Potassium Channels in Porcine Coronary Arterial Myocytes

N. Standen, C. Dart, 1994 .

Caveolar disruption causes contraction of rat femoral arteries via reduced basal NO release and subsequent closure of BKCa channels

C. Dart, T. Kamishima, J. Quayle, 2015, PeerJ.

The dependence of Ag+ block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter

M. Sutcliffe, P. Spencer, E. C. Conley, 1998, The Journal of physiology.

Soluble adenylyl cyclase links Ca2+ entry to Ca2+/cAMP-response element binding protein (CREB) activation in vascular smooth muscle

C. Dart, Tony Parker, Kai-Wen Wang, 2019, Scientific Reports.

The Importance of Pore-Forming Toxins in Multiple Organ Injury and Dysfunction

C. Dart, C. Toh, S. Abrams, 2022, Biomedicines.

Calcium/calmodulin‐dependent kinase 2 mediates Epac‐induced spontaneous transient outward currents in rat vascular smooth muscle

Edward S A Humphries, C. Dart, T. Kamishima, 2017, The Journal of physiology.

TRPV4 and KCa ion channels functionally couple as osmosensors in the paraventricular nucleus

C. Dart, R. Barrett-Jolley, N. Nunn, 2015, British journal of pharmacology.

Human CRP Defends against the Toxicity of Circulating Histones

J. Thachil, N. Zhang, C. Dart, 2013, The Journal of Immunology.

Circulating histones are mediators of trauma-associated lung injury.

N. Zhang, A. Kipar, Weiping Yu, 2013, American journal of respiratory and critical care medicine.

Calmodulin variant E140G associated with long QT syndrome impairs CaMKIIδ autophosphorylation and L-type calcium channel inactivation

S. Antonyuk, N. Helassa, C. Dart, 2022, The Journal of biological chemistry.

Na(+)‐HCO3‐ symport in the sheep cardiac Purkinje fibre.

R. Vaughan-Jones, C. Dart, R D Vaughan-Jones, 1992, The Journal of physiology.

The PSD95–nNOS interface

M. Courtney, C. Dart, M. Leyland, 2005, The Journal of cell biology.

The PSD95–nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death

M. Courtney, C. Dart, M. Leyland, 2004 .

The selectivity filter of a potassium channel, murine Kir2.1, investigated using scanning cysteine mutagenesis

M. Sutcliffe, P. Spencer, C. Dart, 1998, The Journal of physiology.

Function and Pharmacology of Spinally-Projecting Sympathetic Pre-Autonomic Neurones in the Paraventricular Nucleus of the Hypothalamus

C. Dart, R. Barrett-Jolley, N. Nunn, 2011, Current neuropharmacology.

Bioenergetic profile of human coronary artery smooth muscle cells and effect of metabolic intervention

Amy E. Chadwick, C. Dart, T. Kamishima, 2017, PloS one.

Adenosine‐activated potassium current in smooth muscle cells isolated from the pig coronary artery.

N. Standen, C. Dart, N B Standen, 1993, The Journal of physiology.

Potassium channels in articular chondrocytes

A. Mobasheri, C. Dart, R. Barrett-Jolley, 2012, Channels.

Potassium Ion Channels Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls

Edward S A Humphries, C. Dart, 2022 .

Direct Interaction between the Actin-binding Protein Filamin-A and the Inwardly Rectifying Potassium Channel, Kir2.1*

Caroline Dart, C. Dart, M. Leyland, 2003, Journal of Biological Chemistry.

Potassium Ion Channels in Articular Chondrocytes Putative Roles in Mechanotransduction, Metabolic Regulation and Cell Proliferation

A. Mobasheri, C. Dart, R. Barrett-Jolley, 2008 .

Soluble adenylyl cyclase links Ca2+ entry to Ca2+/cAMP-response element binding protein (CREB) activation in vascular smooth muscle

C. Dart, Tony Parker, Kai-Wen Wang, 2019, Scientific Reports.

TRPC1 channel clustering during store-operated Ca2+ entry in keratinocytes

C. Dart, R. Barrett-Jolley, R. L. Evans, 2023, Frontiers in Physiology.

Deep-Channel uses deep neural networks to detect single-molecule events from patch-clamp data

Frans Coenen, Yalin Zheng, Numan Celik, 2019, Communications Biology.

The Role of the Membrane Potential in Chondrocyte Volume Regulation

Ali Mobasheri, Rebecca Lewis, Caroline Dart, 2011, Journal of cellular physiology.

Small-angle X-ray scattering and NMR studies of the conformation of the PDZ region of SAP97 and its interactions with Kir2.1.

L. Lian, B. Goult, A. Kitmitto, 2007, Biochemistry.

Interaction with caveolin‐1 modulates vascular ATP‐sensitive potassium (KATP) channel activity

C. Dart, R. Barrett-Jolley, G. Purves, 2010, The Journal of physiology.

Structural diversity of the cAMP-dependent protein kinase regulatory subunit in Caenorhabditis elegans.

M. Prescott, H. Rees, C. Dart, 2013, Cellular signalling.

Evidence for involvement of A‐kinase anchoring protein in activation of rat arterial KATP channels by protein kinase A

N. Standen, C. Dart, Y. Hayabuchi, 2001, The Journal of physiology.

Direct block of native and cloned (Kir2.1) inward rectifier K+ channels by chloroethylclonidine

N. Standen, C. Dart, R. Barrett-Jolley, 1999, British journal of pharmacology.

Store-operated calcium channels in skin

C. Dart, R. L. Evans, Declan Manning, 2022, Frontiers in Physiology.

Editorial: The role of calcium and calcium binding proteins in cell physiology and disease

N. Helassa, C. Fahlke, C. Dart, 2023, Frontiers in Physiology.

An Alternatively Spliced Isoform of PSD-93/Chapsyn 110 Binds to the Inwardly Rectifying Potassium Channel, Kir2.1*

C. Dart, M. Leyland, 2004, Journal of Biological Chemistry.

Long QT syndrome‐associated calmodulin variants disrupt the activity of the slowly activating delayed rectifier potassium channel

N. Helassa, C. Dart, R. Barrett-Jolley, 2023, The Journal of physiology.

Targeting of an A Kinase-anchoring Protein, AKAP79, to an Inwardly Rectifying Potassium Channel, Kir2.1*

C. Dart, M. Leyland, 2001, The Journal of Biological Chemistry.

The possible role of a disulphide bond in forming functional Kir2.1 potassium channels

M. Sutcliffe, P. Stanfield, P. Spencer, 1999, Pflügers Archiv.

Verdict in the smooth muscle KATP channel case: guilty of blood pressure control but innocent of sudden death phenotype.

C. Dart, 2014, Hypertension.

Lipid microdomains and the regulation of ion channel function.

C. Dart, 2010, The Journal of physiology.