S. Shimizu

发表

The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma.

Y. Doki, M. Mori, H. Nagano, 2010, Journal of hepatology.

Involvement of STAT3-regulated hepatic soluble factors in attenuation of stellate cell activity and liver fibrogenesis in mice.

N. Hayashi, N. Hiramatsu, A. Hosui, 2011, Biochemical and biophysical research communications.

BH3-only Activator Proteins Bid and Bim Are Dispensable for Bak/Bax-dependent Thrombocyte Apoptosis Induced by Bcl-xL Deficiency

N. Hayashi, N. Hiramatsu, Xiao-Ming Yin, 2011, The Journal of Biological Chemistry.

Mcl-1 and Bcl-xL regulate Bak/Bax-dependent apoptosis of the megakaryocytic lineage at multistages

Wei Li, N. Hayashi, N. Hiramatsu, 2012, Cell Death and Differentiation.

Bak deficiency inhibits liver carcinogenesis: a causal link between apoptosis and carcinogenesis.

N. Hayashi, N. Hiramatsu, E. Morii, 2012, Journal of hepatology.

Mcl‐1 and Bcl‐xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver

L. Hennighausen, N. Hayashi, N. Hiramatsu, 2009, Hepatology.

The Bcl-2 Homology Domain 3 (BH3)-only Proteins Bim and Bid Are Functionally Active and Restrained by Anti-apoptotic Bcl-2 Family Proteins in Healthy Liver*

N. Hiramatsu, T. Kodama, M. Shigekawa, 2013, The Journal of Biological Chemistry.

BH3‐only protein bid participates in the Bcl‐2 network in healthy liver cells

L. Hennighausen, N. Hayashi, N. Hiramatsu, 2009, Hepatology.

Carbamazepine promotes liver regeneration and survival in mice.

N. Hiramatsu, T. Kodama, M. Shigekawa, 2013, Journal of hepatology.

Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet

N. Hayashi, N. Hiramatsu, K. Ohkawa, 2010, Journal of Gastroenterology.

Gastrointestinal , Hepatobiliary , and Pancreatic Pathology Pancreatic STAT 3 Protects Mice against Caerulein-Induced Pancreatitis via PAP 1 Induction

S. Akira, N. Hiramatsu, K. Takeda, 2012 .

Pancreatic STAT3 protects mice against caerulein-induced pancreatitis via PAP1 induction.

S. Akira, N. Hiramatsu, K. Takeda, 2012, The American journal of pathology.

The Bcl‐xL inhibitor, ABT‐737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib

N. Hayashi, N. Hiramatsu, A. Hosui, 2010, Hepatology.

Valine, the branched-chain amino acid, suppresses hepatitis C virus RNA replication but promotes infectious particle formation.

N. Hayashi, N. Hiramatsu, A. Hosui, 2013, Biochemical and biophysical research communications.

Delayed‐onset caspase‐dependent massive hepatocyte apoptosis upon fas activation in bak/bax‐deficient mice

N. Hayashi, N. Hiramatsu, Y. Tsujimoto, 2011, Hepatology.

Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice.

N. Hayashi, A. Hosui, A. Ido, 2010, Gastroenterology.

Evaluation of the effects of combination therapy with branched‐chain amino acid and zinc supplements on nitrogen metabolism in liver cirrhosis

A. Ono, K. Ikezawa, S. Shimizu, 2007, Hepatology research : the official journal of the Japan Society of Hepatology.

Invariant natural killer T cell deficiency leads to the development of spontaneous liver inflammation dependent on γδT cells in mice

N. Hiramatsu, T. Kodama, Teppei Yoshioka, 2015, Journal of Gastroenterology.

Interleukin-1β enhances the production of soluble MICA in human hepatocellular carcinoma

N. Hayashi, N. Hiramatsu, A. Hosui, 2012, Cancer Immunology, Immunotherapy.

Differential alteration of CD56bright and CD56dim natural killer cells in frequency, phenotype, and cytokine response in chronic hepatitis C virus infection

N. Hayashi, N. Hiramatsu, T. Tatsumi, 2011, Journal of Gastroenterology.

Peripheral nerve regeneration by the in vitro differentiated-human bone marrow stromal cells with Schwann cell property.

S. Shimizu, M. Dezawa, Yutaka Itokazu, 2007, Biochemical and biophysical research communications.

Expression of CD133 confers malignant potential by regulating metalloproteinases in human hepatocellular carcinoma.

N. Hayashi, T. Tatsumi, T. Takehara, 2010, Journal of hepatology.

Sorafenib enhances proteasome inhibitor-induced cell death via inactivation of Akt and stress-activated protein kinases

T. Takehara, M. Harada, S. Shimizu, 2014, Journal of Gastroenterology.

Synthetic lethal interaction of combined CD26 and Bcl‐xL inhibition is a powerful anticancer therapy against hepatocellular carcinoma

H. Nagano, N. Hiramatsu, T. Kodama, 2015, Hepatology research : the official journal of the Japan Society of Hepatology.

Interferon-α suppresses hepatitis B virus enhancer II activity via the protein kinase C pathway.

N. Hayashi, N. Hiramatsu, A. Hosui, 2012, Virology.

Fatal exacerbation of type B chronic hepatitis triggered by changes in relaxed circular viral DNA synthesis and virion secretion.

N. Hayashi, K. Ohkawa, A. Hosui, 2010, Biochemical and biophysical research communications.

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

N. Hayashi, N. Hiramatsu, A. Hosui, 2012, International journal of cancer.

Alterations in microRNA expression profile in HCV-infected hepatoma cells: involvement of miR-491 in regulation of HCV replication via the PI3 kinase/Akt pathway.

N. Hayashi, N. Hiramatsu, A. Hosui, 2011, Biochemical and biophysical research communications.

Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice.

Wei Li, Y. Doki, M. Mori, 2011, The Journal of clinical investigation.

Altered interferon-alpha-signaling in natural killer cells from patients with chronic hepatitis C virus infection.

N. Hayashi, N. Hiramatsu, T. Tatsumi, 2010, Journal of hepatology.

The combination therapy of α‐galactosylceramide and 5‐fluorouracil showed antitumor effect synergistically against liver tumor in mice

N. Hayashi, N. Hiramatsu, A. Hosui, 2013, International journal of cancer.

Activation of the Mitochondrial Apoptotic Pathway Produces Reactive Oxygen Species and Oxidative Damage in Hepatocytes That Contribute to Liver Tumorigenesis

N. Hiramatsu, T. Kodama, M. Shigekawa, 2015, Cancer Prevention Research.

That Contribute to Liver Tumorigenesis Reactive Oxygen Species and Oxidative Damage in Hepatocytes Activation of the Mitochondrial Apoptotic Pathway Produces

N. Hiramatsu, T. Kodama, M. Shigekawa, 2015 .