A. Pawlik

发表

Genome analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of the etiologic agent of tuberculosis

E. Willery, C. Locht, J. Tap, 2013, Nature Genetics.

Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

R. Brosch, M. Daffé, Wladimir Malaga, 2014, Proceedings of the National Academy of Sciences.

Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection.

N. Honoré, Sang-Nae Cho, R. Brosch, 2017, Cell reports.

CD4 T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against PulmonaryMycobacterium tuberculosis Infection

R. Brosch, C. Leclerc, G. Bancroft, 2018 .

CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection

R. Brosch, C. Leclerc, G. Bancroft, 2016, PLoS pathogens.

A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus

C. Biot, L. Kremer, J. Lelièvre, 2016, Molecular microbiology.

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes.

J. Herrmann, A. Pawlik, V. Le Moigne, 2018, Journal of visualized experiments : JoVE.

Identification and characterization of the genetic changes responsible for the characteristic smooth‐to‐rough morphotype alterations of clinically persistent Mycobacterium abscessus

J. Coppee, N. Honoré, R. Brosch, 2013, Molecular microbiology.

A novel pathway for megakaryocyte production following in vivo conditional eradication of integrin αIIb expressing cells Running title: Transcriptional profiling of bone marrow recovery

X. Gidrol, B. Jacquelin, T. Kortulewski, 2005 .

Novel Microarray-Based Method for Estimating Exposure to Ionizing Radiation

V. Frouin, X. Gidrol, C. Lucchesi, 2006, Radiation research.

A Specific Polymorphism in Mycobacterium tuberculosis H37Rv Causes Differential ESAT-6 Expression and Identifies WhiB6 as a Novel ESX-1 Component

R. Brosch, A. Pawlik, W. Frigui, 2014, Infection and Immunity.

Changes in transcriptome after in vivo exposure to ionising radiation reveal a highly specialised liver response

P. Delmar, A. Pawlik, D. Thierry, 2009, International journal of radiation biology.

Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

E. Willery, C. Locht, J. Tap, 2020 .

A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity.

R. Brosch, P. Charneau, L. Majlessi, 2022, Cell reports.

A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity

R. Brosch, P. Charneau, L. Majlessi, 2022, Mucosal Immunology.

1 pks 5-recombination-mediated surface remodelling in Mycobacterium tuberculosis 1 emergence 2 3

R. Brosch, Étienne, L. Majlessi, 2015 .

Novel pathway for megakaryocyte production after in vivo conditional eradication of integrin alphaIIb-expressing cells.

X. Gidrol, B. Jacquelin, T. Kortulewski, 2005, Blood.

Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis

C. Consolandi, M. Severgnini, C. Peano, 2017, Mucosal Immunology.

Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

J. Coppee, R. Brosch, J. Gaillard, 2019, bioRxiv.

Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts

J. Parkhill, R. Brosch, C. Bouchier, 2021, Microbial genomics.

De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

C. Demangel, J. Bertrand-Michel, Wladimir Malaga, 2021, bioRxiv.

Transcriptome Characterization Uncovers the Molecular Response of Hematopoietic Cells to Ionizing Radiation

S. Baulande, A. Pawlik, O. Alibert, 2011, Radiation research.

Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria

N. Honoré, R. Brosch, Varun Khanna, 2016, Proceedings of the National Academy of Sciences.

TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages

C. Médigue, V. Barbe, S. Mangenot, 2020, Nature Communications.

The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis

R. Brosch, A. Lemassu, M. Daffé, 2016, Molecular microbiology.

Lsr2 Is an Important Determinant of Intracellular Growth and Virulence in Mycobacterium abscessus

L. Kremer, Frédéric Crémazy, J. Gaillard, 2019, Front. Microbiol..

pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence

R. Brosch, L. Majlessi, M. Daffé, 2016, Nature Microbiology.

Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis

R. Brosch, L. Majlessi, J. Herrmann, 2015, Scientific Reports.

Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli

R. Brosch, R. Antoine, Wladimir Malaga, 2021, Nature Microbiology.

Unexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and Immunogenicity

R. Brosch, R. Warren, L. Majlessi, 2018, Genome biology and evolution.

Overexpression of proinflammatory TLR‐2‐signalling lipoproteins in hypervirulent mycobacterial variants

J. Coppee, B. Monsarrat, R. Brosch, 2011, Cellular microbiology.