S. Yoshioka

发表

Correlations between molecular mobility and chemical stability during storage of amorphous pharmaceuticals.

S. Yoshioka, Y. Aso, 2007, Journal of pharmaceutical sciences.

Assessment of Shelf-Life Equivalence of Pharmaceutical Products

S. Yoshioka, Y. Aso, S. Kojima, 1997 .

Physical Stability and Protein Stability of Freeze-Dried Cakes During Storage at Elevated Temperatures

S. Yoshioka, S. Kojima, K. Izutsu, 1994, Pharmaceutical Research.

Effect of temperature on mechanisms of drug release and matrix degradation of poly(d,l-lactide) microspheres

Sumie Yoshioka, Yukio Aso, S. Yoshioka, 1994 .

Molecular mobility of nifedipine-PVP and phenobarbital-PVP solid dispersions as measured by 13C-NMR spin-lattice relaxation time.

S. Yoshioka, Y. Aso, 2006, Journal of pharmaceutical sciences.

Kinetics of hydrolysis of meclofenoxate hydrochloride in human plasma

S. Yoshioka, Y. Aso, M. Uchiyama, 1987, The Journal of pharmacy and pharmacology.

Effect of Sugars on the Molecular Motion of Freeze-Dried Protein Formulations Reflected by NMR Relaxation Times

M. Pikal, S. Yoshioka, Y. Aso, 2011, Pharmaceutical Research.

Inactivation and Aggregation of β-Galactosidase in Lyophilized Formulation Described by Kohlrausch-Williams-Watts Stretched Exponential Function

S. Yoshioka, Y. Aso, S. Kojima, 2003, Pharmaceutical Research.

The Effect of Excipients on the Molecular Mobility of Lyophilized Formulations, as Measured by Glass Transition Temperature and NMR Relaxation-Based Critical Mobility Temperature

Shigeo Kojima, Sumie Yoshioka, Yukio Aso, 2004, Pharmaceutical Research.

Significance of Local Mobility in Aggregation of β-Galactosidase Lyophilized with Trehalose, Sucrose or Stachyose

S. Yoshioka, Y. Aso, Tamaki Miyazaki, 2007, Pharmaceutical Research.

Glass transition-related changes in molecular mobility below glass transition temperature of freeze-dried formulations, as measured by dielectric spectroscopy and solid state nuclear magnetic resonance.

S. Yoshioka, Y. Aso, 2005, Journal of pharmaceutical sciences.

Temperature Dependence of Bimolecular Reactions Associated with Molecular Mobility in Lyophilized Formulations

S. Yoshioka, Y. Aso, S. Kojima, 2000, Pharmaceutical Research.

Molecular Mobility of Protein in Lyophilized Formulations Linked to the Molecular Mobility of Polymer Excipients, as Determined by High Resolution 13C Solid-State NMR

T. Fujiwara, S. Sakurai, H. Akutsu, 1999, Pharmaceutical Research.

Temperature- and glass transition temperature-dependence of bimolecular reaction rates in lyophilized formulations described by the Adam-Gibbs-Vogel equation.

S. Yoshioka, Y. Aso, S. Kojima, 2004, Journal of pharmaceutical sciences.

Molecular mobility of lyophilized poly(vinylpyrrolidone) and methylcellulose as determined by the laboratory and rotating frame spin-lattice relaxation times of 1H and 13C.

S. Yoshioka, Y. Aso, S. Kojima, 2003, Chemical & pharmaceutical bulletin.

Different molecular motions in lyophilized protein formulations as determined by laboratory and rotating frame spin-lattice relaxation times.

S. Yoshioka, Y. Aso, S. Kojima, 2002, Journal of pharmaceutical sciences.

Effect of high molecular mobility of poly(vinyl alcohol) on protein stability of lyophilized gamma-globulin formulations.

S. Yoshioka, Y. Aso, S. Kojima, 1998, Journal of pharmaceutical sciences.

Dependence of the Molecular Mobility and Protein Stability of Freeze-Dried γ-Globulin Formulations on the Molecular Weight of Dextran

S. Yoshioka, Y. Aso, S. Kojima, 1997, Pharmaceutical Research.

Effect of Water Mobility on Drug Hydrolysis Rates in Gelatin Gels

S. Yoshioka, Y. Aso, T. Terao, 1992, Pharmaceutical Research.

Stability of β-Galactosidase, a Model Protein Drug, Is Related to Water Mobility as Measured by 17O Nuclear Magnetic Resonance (NMR)

S. Yoshioka, Y. Aso, K. Izutsu, 2004, Pharmaceutical Research.

Inactivation Kinetics of Enzyme Pharmaceuticals in Aqueous Solution

S. Yoshioka, Y. Aso, K. Izutsu, 1991, Pharmaceutical Research.

The Aggregation of Bovine Serum Albumin in Solution and in the Solid State

S. Yoshioka, T. Terao, G. Jordan, 1994, The Journal of pharmacy and pharmacology.

Stabilizing effect of amphiphilic excipients on the freeze‐thawing and freeze‐drying of lactate dehydrogenase

S. Yoshioka, K. Izutsu, T. Terao, 1994, Biotechnology and bioengineering.

Effect of Cryoprotectants on the Eutectic Crystallization of NaCl in Frozen Solutions Studied by Differential Scanning Calorimetry (DSC) and Broad-Line Pulsed NMR.

S. Yoshioka, S. Kojima, K. Izutsu, 1995 .

A Quantitative Assessment of the Significance of Molecular Mobility as a Determinant for the Stability of Lyophilized Insulin Formulations

S. Yoshioka, Y. Aso, 2005, Pharmaceutical Research.

Effects of storage on the physicochemical properties and release characteristics of progesterone-loaded poly(l-lactide) microspheres

S. Yoshioka, Y. Aso, T. Terao, 1993 .

Effect of the Binding of Water to Excipients as Measured by 2H-NMR Relaxation Time on Cephalothin Decomposition Rate

S. Yoshioka, T. Terao, Y. Aso, 1994 .

Synthetic hydrated aluminum silicates as oral adsorbents of potassium ion.

S. Yoshioka, Y. Suzuki, M. Uchiyama, 1986, Chemical & pharmaceutical bulletin.

Effect of sugars on storage stability of lyophilized liposome/DNA complexes with high transfection efficiency.

Y. Maitani, S. Yoshioka, Y. Aso, 2008, International journal of pharmaceutics.

Preparation of poly(l-lactide) microspheres of different crystalline morphology and effect of crystalline morphology on drug release rate

Sumie Yoshioka, Yukio Aso, S. Yoshioka, 1991 .

Entrapment of Proteins in Poly(L-Lactide) Microspheres Using Reversed Micelle Solvent Evaporation

S. Yoshioka, Y. Aso, A. Po, 1994, Pharmaceutical Research.

SOME DETERMINANTS OF MORPHOLOGY AND RELEASE RATE FROM POLY(L)LACTIC ACID MICROSPHERES

J. Dressman, A. Kishida, S. Yoshioka, 1990 .

Effect of freezing rate on physical stability of lyophilized cationic liposomes.

S. Yoshioka, Y. Aso, 2005, Chemical & pharmaceutical bulletin.

The Physical Stability of Amorphous Nifedipine Determined by Isothermal Microcalorimetry.

S. Yoshioka, Y. Aso, S. Kojima, 1995 .

The Effect of Salts on the Stability of β-Galactosidase in Aqueous Solution, as Related to the Water Mobility

S. Yoshioka, Y. Aso, K. Izutsu, 1993, Pharmaceutical Research.

Effect of mannitol crystallinity on the stabilization of enzymes during freeze-drying.

S. Yoshioka, K. Izutsu, T. Terao, 1994, Chemical & pharmaceutical bulletin.

Prediction of Glass Transition Temperature of Freeze-Dried Formulations by Molecular Dynamics Simulation

S. Yoshioka, Y. Aso, S. Kojima, 2003, Pharmaceutical Research.

Stability of Drugs and Dosage Forms

V. Stella, S. Yoshioka, 2000, Springer US.

Molecular mobility-based estimation of the crystallization rates of amorphous nifedipine and phenobarbital in poly(vinylpyrrolidone) solid dispersions.

Shigeo Kojima, Sumie Yoshioka, Yukio Aso, 2004, Journal of pharmaceutical sciences.

Miscibility of nifedipine and hydrophilic polymers as measured by (1)H-NMR spin-lattice relaxation.

Sumie Yoshioka, Yukio Aso, S. Yoshioka, 2007, Chemical & pharmaceutical bulletin.

Effects of Sugars and Polymers on Crystallization of Poly(ethylene glycol) in Frozen Solutions: Phase Separation Between Incompatible Polymers

J. Carpenter, T. Randolph, S. Yoshioka, 1996, Pharmaceutical Research.

Feasibility of using isothermal microcalorimetry to evaluate the physical stability of amorphous nifedipine and phenobarbital

S. Yoshioka, Y. Aso, S. Kojima, 2001 .

β-Relaxation of Insulin Molecule in Lyophilized Formulations Containing Trehalose or Dextran as a Determinant of Chemical Reactivity

S. Yoshioka, Y. Aso, Tamaki Miyazaki, 2006, Pharmaceutical Research.

Decreased Protein-Stabilizing Effects of Cryoprotectants Due to Crystallization

S. Yoshioka, K. Izutsu, T. Terao, 1993, Pharmaceutical Research.

Degradation rate of lyophilized insulin, exhibiting an apparent Arrhenius behavior around glass transition temperature regardless of significant contribution of molecular mobility.

S. Yoshioka, Y. Aso, Tamaki Miyazaki, 2006, Journal of pharmaceutical sciences.

Negligible contribution of molecular mobility to the degradation rate of insulin lyophilized with poly(vinylpyrrolidone).

S. Yoshioka, Y. Aso, Tamaki Miyazaki, 2006, Journal of pharmaceutical sciences.

Increased Stabilizing Effects of Amphiphilic Excipients on Freeze-Drying of Lactate Dehydrogenase (LDH) by Dispersion into Sugar Matrices

S. Yoshioka, S. Kojima, K. Izutsu, 1995, Pharmaceutical Research.

Kinetics and mechanism of the solid-state decomposition of propantheline bromide.

S. Yoshioka, M. Uchiyama, 1986, Journal of pharmaceutical sciences.

Physical stability of amorphous acetanilide derivatives improved by polymer excipients.

Sumie Yoshioka, Yukio Aso, S. Yoshioka, 2006, Chemical & pharmaceutical bulletin.

Crystallization rate of amorphous nifedipine analogues unrelated to the glass transition temperature.

Sumie Yoshioka, Yukio Aso, S. Yoshioka, 2007, International journal of pharmaceutics.

Differences in crystallization rate of nitrendipine enantiomers in amorphous solid dispersions with HPMC and HPMCP.

S. Yoshioka, Y. Aso, T. Kawanishi, 2011, International journal of pharmaceutics.

Is Stability Prediction Possible for Protein Drugs? Denaturation Kinetics of β- Galactosidase in Solution

S. Yoshioka, Y. Aso, S. Kojima, 1994, Pharmaceutical Research.

Ability of polyvinylpyrrolidone and polyacrylic acid to inhibit the crystallization of amorphous acetaminophen.

Shigeo Kojima, Sumie Yoshioka, Yukio Aso, 2004, Journal of pharmaceutical sciences.

A one-dimensional kalman filter for peak resolution

Y. Hayashi, S. Yoshioka, Y. Takeda, 1988 .

Feasibility of 19F-NMR for assessing the molecular mobility of flufenamic acid in solid dispersions.

S. Yoshioka, Y. Aso, T. Kawanishi, 2009, Chemical & pharmaceutical bulletin.

Epimerization and Hydrolysis of Etoposide Analogues in Aqueous Solution

Y. Hayashi, Y. Nishimura, Y. Arata, 1989 .

Nonlinear estimation of kinetic parameters for solid-state hydrolysis of water-soluble drugs. II: Rational presentation mode below the critical moisture content.

J. Carstensen, S. Yoshioka, 1990, Journal of pharmaceutical sciences.

Drug release from poly(dl-lactide) microspheres controlled by γ-irradiation

Shigeo Kojima, S. Yoshioka, Y. Aso, 1995 .

Wide-ranging molecular mobilities of water in active pharmaceutical ingredient (API) hydrates as determined by NMR relaxation times.

S. Yoshioka, Y. Aso, T. Kawanishi, 2008, Journal of pharmaceutical sciences.

Stability of solid dosage forms. I. Hydrolysis of meclofenoxate hydrochloride in the solid state.

S. Yoshioka, T. Shibazaki, A. Ejima, 1982 .

Nonlinear estimation of kinetic parameters for solid-state hydrolysis of water-soluble drugs.

S. Yoshioka, M. Uchiyama, 1986, Journal of pharmaceutical sciences.

Statistical evaluation of non-isothermal prediction of drug stability. II: Experimental design for practical drug products

S. Yoshioka, Y. Aso, M. Uchiyama, 1988 .

Isothermal and Nonisothermal Kinetics in the Stability Prediction of Vitamin A Preparations

S. Yoshioka, Y. Aso, Y. Takeda, 1990, Pharmaceutical Research.

A Bayesian Approach to Arrhenius Prediction of Shelf-Life

Sumie Yoshioka, Xiang-Yao Su, Alain Li Wan Po, 1994, Pharmaceutical Research.

Predicting shelf-lives of pharmaceutical products

X. Y. Su, A. Li Wan Po, S. Yoshioka, 1994 .

Effect of water on the molecular mobility of sucrose and poly(vinylpyrrolidone) in a colyophilized formulation as measured by (13)C-NMR relaxation time.

G. Zografi, S. Yoshioka, Y. Aso, 2002, Chemical & pharmaceutical bulletin.

Aggregates Formed During Storage of β-Galactosidase in Solution and in the Freeze-Dried State

S. Yoshioka, Y. Aso, K. Izutsu, 1993, Pharmaceutical Research.

Thermally controlled protein release from gelatin–dextran hydrogels

Shigeo Kojima, Sumie Yoshioka, Yukio Aso, 1999 .

One-dimensional Kalman filter in a robot system for total analysis of solid dosage formulations

R. Matsuda, Y. Hayashi, S. Yoshioka, 1988 .

Shannon Information Retrieved from Overlapped Chromatographic Peaks with Kaiman Filter

Y. Hayashi, S. Yoshioka, Y. Takeda, 1989 .

Base-induced polymer hydrolysis in poly (β-hydroxybutyrate/β-hydroxyvalerate) matrices

A. Kishida, S. Yoshioka, Y. Aso, 1991 .

Usefulness of the Kohlrausch-Williams-Watts Stretched Exponential Function to Describe Protein Aggregation in Lyophilized Formulations and the Temperature Dependence Near the Glass Transition Temperature

S. Yoshioka, Y. Aso, S. Kojima, 2001, Pharmaceutical Research.

FORMULATION-ASSISTED BIODEGRADABLE POLYMER MATRICES

A. Kishida, S. Yoshioka, M. Uchiyama, 1989 .

Rational storage conditions for accelerated testing of stability of solid pharmaceuticals.

J. Carstensen, S. Yoshioka, 1990, Journal of pharmaceutical sciences.

Limits to the concept of solid-state stability.

J. Carstensen, S. Yoshioka, M. Uchiyama, 1987, Journal of pharmaceutical sciences.