Hong-Yu Hu

Hong-Yu Hu, Yuan-yuan Xie, Lei-Lei Jiang, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

α-to-β Structural Transformation of Ovalbumin: Heat and pH Effects

Hong-Yu Hu, H. Du, H. Hu, 2000 .

Aggregation of Polyglutamine-Expanded Ataxin-7 Specifically Sequesters Ubiquitin-Specific Protease 22 and Deteriorates Its Deubiquitinating Function in SAGA Complex *

Jian Zhao, Hong-Yu Hu, Wen-tian He, 2015 .

PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates

H. Yue, Hong-Yu Hu, Lei-Lei Jiang, 2021, Scientific Reports.

Backbone and side-chain 1H, 15N and 13C resonance assignments of S18Y mutant of ubiquitin carboxy-terminal hydrolase L1

K. Sze, Hong-Yu Hu, Ho-Sum Tse, 2011, Biomolecular NMR assignments.

Backbone and side-chain 1 H , 15 N and 13 C resonance assignments of S 18 Y mutant of ubiquitin carboxy-terminal hydrolase L 1

K. Sze, Hong-Yu Hu, Ho-Sum Tse, 2011 .

Study of protein-protein interactions by fluorescence of tryptophan analogs: application to immunoglobulin G binding domain of streptococcal protein G.

Hong-Yu Hu, Q. Li, H. Du, 2003, Biopolymers.

Secondary structural formation of alpha-synuclein amyloids as revealed by g-factor of solid-state circular dichroism.

Hong-Yu Hu, Yuan-yuan Xie, Jian-Hua He, 2006, Biopolymers.

A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein.

Jun Hu, Hong-Yu Hu, L. Tang, 2003, Biochemistry.

[Study on chemical constituents of bark of Paeonia suffruticosa].

Hong-Yu Hu, Yi-min Zhao, Yu Yang, 2006, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML

Jian-Hua Tong, Guang-Biao Zhou, Marion Jeanne, 2010, Science.

Solid-state NMR reveals the structural transformation of the TDP-43 amyloidogenic region upon fibrillation.

J. Wang, Hong-Yu Hu, Junxia Lu, 2020, Journal of the American Chemical Society.

Oxidation of Long Chain Primary Alcohols to Acids over the Quaternary Ammonium Peroxotungstophosphate Catalyst System

Meijuan Zhou, Hong-Yu Hu, Changping Wei, 2001 .

Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone

F. G. van der Goot, Hong-Yu Hu, Wen-tian He, 2016, PloS one.

Sequestration of cellular interacting partners by protein aggregates: implication in a loss‐of‐function pathology

Hong-Yu Hu, Hui Yang, 2016, The FEBS journal.

The N-terminal dimerization is required for TDP-43 splicing activity

Hong-Yu Hu, Jian-Hua He, Jun-Ye Hong, 2017, Scientific Reports.

Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation

Jian Zhao, Hong-Yu Hu, Wen-tian He, 2016, Scientific Reports.

TDP‐35 sequesters TDP‐43 into cytoplasmic inclusions through binding with RNA

Hong-Yu Hu, Hai-Yin Li, Leilei Jiang, 2015, FEBS letters.

Structural Analysis of the UBA Domain of X-linked Inhibitor of Apoptosis Protein Reveals Different Surfaces for Ubiquitin-Binding and Self-Association

B. Wong, K. Sze, Hong-Yu Hu, 2011, PloS one.

Different Roles for Two Ubiquitin-like Domains of ISG15 in Protein Modification*

Dong-er Zhang, Yong-Gang Chang, Hong-Yu Hu, 2008, Journal of Biological Chemistry.

A Peptide Motif Consisting of Glycine, Alanine, and Valine Is Required for the Fibrillization and Cytotoxicity of Human α-Synuclein†

Jun Hu, Hong-Yu Hu, L. Tang, 2003 .

HSP90 recognizes the N-terminus of huntingtin involved in regulation of huntingtin aggregation by USP19

H. Yue, Hong-Yu Hu, Wen-tian He, 2017, Scientific Reports.

Domain Analysis Reveals That a Deubiquitinating Enzyme USP13 Performs Non-Activating Catalysis for Lys63-Linked Polyubiquitin

Hong-Yu Hu, Yu-Hang Zhang, A. Song, 2011, PloS one.

Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin.

Jian Zhao, Hong-Yu Hu, Hui Yang, 2014, Structure.

A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms

D. Shore, Yong Chen, M. Lei, 2011, Nature Structural &Molecular Biology.

Epitaxial growth of peptide nanofilaments on inorganic surfaces: effects of interfacial hydrophobicity/hydrophilicity.

Yi Zhang, Jun Hu, L. Tang, 2006, Angewandte Chemie.

Solution structure of the ubiquitin‐like domain of human DC‐UbP from dendritic cells

Yi Yu, Xuetao Cao, Yong-Gang Chang, 2005, Protein science : a publication of the Protein Society.

Co-Chaperone HSJ1a Dually Regulates the Proteasomal Degradation of Ataxin-3

Hong-Yu Hu, Yu-Hang Zhang, A. Song, 2011, PloS one.

PolyQ‐expanded huntingtin and ataxin‐3 sequester ubiquitin adaptors hHR23B and UBQLN2 into aggregates via conjugated ubiquitin

H. Yue, Hong-Yu Hu, Wen-tian He, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Identification, expression, and purification of a unique stable domain from human HSPC144 protein.

Yong-Gang Chang, Hong-Yu Hu, Yong-Guang Gao, 2005, Protein expression and purification.

Three new paeonidanin-type monoterpene glycosides from Paeonia suffruticosa Andr.

Yimin Zhao, Hong-Yu Hu, Yang Zhang, 2010 .

Crystallization and preliminary crystallographic studies of Escherichia coli CcmG/DsbE protein.

Z. Xia, Hong-Yu Hu, Q. Li, 2003, Acta crystallographica. Section D, Biological crystallography.

Solution structure of the ubiquitin‐associated domain of human BMSC‐UbP and its complex with ubiquitin

Xuetao Cao, Yong-Gang Chang, Hong-Yu Hu, 2006, Protein science : a publication of the Protein Society.

Structural Transformation of the Tandem Ubiquitin-Interacting Motifs in Ataxin-3 and Their Cooperative Interactions with Ubiquitin Chains

Xue Gao, Hong-Yu Hu, Yu Peng, 2010, PloS one.

[Secreted expression of porcine interferon-gamma gene in Pichia pastoris].

Hong-Yu Hu, Xiao-Ling Chen, A. Lin, 2005, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Assembly of alpha-synuclein fibrils in nanoscale studied by peptide truncation and AFM.

Jun Hu, Hong-Yu Hu, Xiao-Jing Lin, 2008, Biochemical and biophysical research communications.

Inhibition of α‐synuclein fibrillization by dopamine analogs via reaction with the amino groups of α‐synuclein

Jun Hu, Hong-Yu Hu, Guo-Qiang Song, 2005 .

Inhibition of α‐synuclein fibrillization by dopamine analogs via reaction with the amino groups of α‐synuclein

Jun Hu, Hong-Yu Hu, Feng Zhang, 2005 .

Structural and mechanistic insights into the arginine/lysine-rich peptide motifs that interact with P97/VCP.

Jian Zhao, Hong-Yu Hu, Shuai Liu, 2013, Biochimica et biophysica acta.

Structural transformation and aggregation of human alpha-synuclein in trifluoroethanol: non-amyloid component sequence is essential and beta-sheet formation is prerequisite to aggregation.

Hong-Yu Hu, Junjie Hu, L. Tang, 2002, Biopolymers.

Structural insights into the specific binding of huntingtin proline-rich region with the SH3 and WW domains.

Yong-Gang Chang, Hong-Yu Hu, N. Jiang, 2006, Structure.

Kinetics of zinc and cadmium dissociation of metallothionein in the presence of chelating agents

Z. Huang, Hong-Yu Hu, Wei‐Qiang Gu, 2010 .

Interaction with Polyglutamine-expanded Huntingtin Alters Cellular Distribution and RNA Processing of Huntingtin Yeast Two-hybrid Protein A (HYPA)*

Hong-Yu Hu, Yuan‐yuan Xie, Jin-Qiao Yuan, 2011, The Journal of Biological Chemistry.

Solution structure of the Magnaporthe oryzae avirulence protein AvrPiz-t

Maili Liu, Xu Zhang, Hong-Yu Hu, 2013, Journal of Biomolecular NMR.

Acceleration of α‐synuclein aggregation by homologous peptides

Jun Hu, Hong-Yu Hu, Xiao-Jing Lin, 2006 .

Acceleration of alpha-synuclein aggregation by homologous peptides.

Feng Zhang, Jun Hu, Hong-Yu Hu, 2006, FEBS letters.

Structural and dynamic studies reveal that the Ala-rich region of ataxin-7 initiates α-helix formation of the polyQ tract but suppresses its aggregation

H. Yue, Hong-Yu Hu, Hui Yang, 2019, Scientific Reports.

Aggregation of Polyglutamine-expanded Ataxin 7 Protein Specifically Sequesters Ubiquitin-specific Protease 22 and Deteriorates Its Deubiquitinating Function in the Spt-Ada-Gcn5-Acetyltransferase (SAGA) Complex*

Jian Zhao, Hong-Yu Hu, Wen-tian He, 2015, The Journal of Biological Chemistry.

Aggregation of polyglutamine-expanded ataxin-3 sequesters its specific interacting partners into inclusions: Implication in a loss-of-function pathology

Jian Zhao, Hong-Yu Hu, Jingjing Li, 2014, Scientific Reports.

Study of the disassembly-assembly process of alpha-synuclein fibrils by in situ atomic force microscopy.

L. Tang, Hong-Yu Hu, Xiaofang Hu, 2006, Micron.

Impacts of vegetation type on soil phosphorus availability and fractions near the alpine timberline of the Tibetan Plateau

Yan Wu, N. Wu, P. Luo, 2011 .

Interaction with synphilin‐1 promotes inclusion formation of α‐synuclein: mechanistic insights and pathological implication

Hong-Yu Hu, Jing Hong, A. Song, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structural Transformation of the Peptide Fragments from the Reactive Center Loops of Serpins: Circular Dichroic Studies

Yun-Neng Chen, Hong-Yu Hu, Song-Qin Xu, 2010 .

Solution structure of the N‐terminal domain of DC‐UbP/UBTD2 and its interaction with ubiquitin

K. Sze, Hong-Yu Hu, A. Song, 2010, Protein science : a publication of the Protein Society.

An Unstructured Region is Required by GAV Homologue for the Fibrillization of Host Proteins

Jun Hu, Hong-Yu Hu, Feng Zhang, 2005, The protein journal.

The C-terminal Helices of Heat Shock Protein 70 Are Essential for J-domain Binding and ATPase Activation*

C. Cao, Hong-Yu Hu, Zi-ren Zhou, 2012, The Journal of Biological Chemistry.

The N-terminal ubiquitin-binding region of ubiquitin-specific protease 28 modulates its deubiquitination function: NMR structural and mechanistic insights.

Naixia Zhang, Hong-Yu Hu, Yi Wen, 2015, The Biochemical journal.

PABPN1 aggregation is driven by Ala expansion and poly(A)-RNA binding, leading to CFIm25 sequestration that impairs alternative polyadenylation

Hong-Yu Hu, Leilei Jiang, Xiao-Fang Yin, 2023, The Journal of biological chemistry.

Structural and Functional Investigations of the N-Terminal Ubiquitin Binding Region of Usp25.

Yanhong Shi, Naixia Zhang, Hong-Yu Hu, 2017, Biophysical journal.

RNA-assisted sequestration of RNA-binding proteins by cytoplasmic inclusions of the C-terminal 35-kDa fragment of TDP-43.

Hong-Yu Hu, Wenlu Guan, Shu-Xian Zhang, 2022, Journal of cell science.

Length of the active-site crossover loop defines the substrate specificity of ubiquitin C-terminal hydrolases for ubiquitin chains.

Hong-Yu Hu, Yu-Hang Zhang, A. Song, 2012, The Biochemical journal.

HSP90 recognizes the N-terminus of huntingtin involved in regulation of huntingtin aggregation by USP19

H. Yue, Hong-Yu Hu, Wen-tian He, 2017, Scientific Reports.

Differential ubiquitin binding of the UBA domains from human c‐Cbl and Cbl‐b: NMR structural and biochemical insights

Yong-Gang Chang, Hong-Yu Hu, Jing Hong, 2008, Protein science : a publication of the Protein Society.

Highly efficient expression and purification system of small-size protein domains in Escherichia coli for biochemical characterization.

Tie-Ying Zhang, Yong-Gang Chang, Hong-Yu Hu, 2006, Protein expression and purification.

The concentration of hydrogen peroxide generated during aggregation of α-synuclein in vitro is lower than 5 nmol/L

Jun Hu, Hong-Yu Hu, Feng Zhang, 2010 .

Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in modulation of huntingtin aggregation.

Hong-Yu Hu, Wen-tian He, Jun-Ye Hong, 2020, The Biochemical journal.

The role of tryptophan in staphylococcal nuclease stability.

Chin-Kun Hu, Michael D Forrest, Ming-Chya Wu, 2010, Biophysical Chemistry.

Coaggregation of polyglutamine (polyQ) proteins is mediated by polyQ-tract interactions and impairs cellular proteostasis

H. Yue, Hong-Yu Hu, Jun-Ye Hong, 2023, Acta biochimica et biophysica Sinica.

Crystal structures of E. coli CcmG and its mutants reveal key roles of the N‐terminal β‐sheet and the fingerprint region

Z. Xia, Hong-Yu Hu, Yong‐Guang Gao, 2006, Proteins.

Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A2-activating Protein*

Hong-Yu Hu, Wenming Yao, Jing Hong, 2009, The Journal of Biological Chemistry.

Interaction with synphilin‐1 promotes inclusion formation of α‐synuclein: mechanistic insights and pathological implication

Hong-Yu Hu, Jing Hong, A. Song, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structural and Redox Properties of the Leaderless DsbE (CcmG) Protein: Both Active-Site Cysteines of the Reduced Form Are Involved in Its Function in the Escherichia coli Periplasm

Wei-qing Wang, Hong-Yu Hu, Gen‐jun Xu, 2001, Biological chemistry.

Solution structure of the Magnaporthe oryzae avirulence protein AvrPiz-t

Maili Liu, Xu Zhang, Hong-Yu Hu, 2013, Journal of Biomolecular NMR.