Mingzhang Gao

发表

Synthesis of carbon-11-labeled piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as new selective PET sigma1 receptor probes.

G. Hutchins, Mingzhang Gao, Min Wang, 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of [11C]Iressa as a new potential PET cancer imaging agent for epidermal growth factor receptor tyrosine kinase.

G. Sledge, K. Miller, Mingzhang Gao, 2006, Bioorganic & medicinal chemistry letters.

Concise and high-yield synthesis of T808 and T808P for radiosynthesis of [(18)F]-T808, a PET tau tracer for Alzheimer's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2014, Bioorganic & medicinal chemistry letters.

The first synthesis of [11C]J147, a new potential PET agent for imaging of Alzheimer's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2013, Bioorganic & medicinal chemistry letters.

A high-yield route to synthesize the P-glycoprotein radioligand [11C]N-desmethyl-loperamide and its parent radioligand [11C]loperamide.

Mingzhang Gao, Min Wang, Q. Zheng, 2013, Bioorganic & medicinal chemistry letters.

Synthesis of (Z)-2-((1H-indazol-3-yl)methylene)-6-[¹¹C]methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one as a new potential PET probe for imaging of the enzyme PIM1.

K. Miller, Mingzhang Gao, Min Wang, 2013, Bioorganic & medicinal chemistry letters.

Synthesis of [11C]HG-10-102-01 as a new potential PET agent for imaging of LRRK2 enzyme in Parkinson's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2017, Bioorganic & medicinal chemistry letters.

Synthesis of carbon-11-labeled aminoalkylindole derivatives as new candidates of cannabinoid receptor radioligands for PET imaging of alcohol abuse.

Mingzhang Gao, Min Wang, Q. Zheng, 2014, Bioorganic & medicinal chemistry letters.

The first radiosynthesis of [(11)C]AZD8931 as a new potential PET agent for imaging of EGFR, HER2 and HER3 signaling.

Mingzhang Gao, Min Wang, Q. Zheng, 2014, Bioorganic & medicinal chemistry letters.

Synthesis of carbon-11-labeled 5-HT6R antagonists as new candidate PET radioligands for imaging of Alzheimer's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2018, Bioorganic & medicinal chemistry letters.

Facile synthesis of carbon-11-labeled cholesterol-based cationic lipids as new potential PET probes for imaging of gene delivery in cancer

G. Hutchins, G. Sledge, K. Miller, 2010, Steroids.

Synthesis of new carbon-11 labeled cyclofenil derivatives for PET imaging of breast cancer estrogen receptors.

G. Hutchins, G. Sledge, K. Miller, 2008, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Characterization of 11C-GSK1482160 for Targeting the P2X7 Receptor as a Biomarker for Neuroinflammation

G. Hutchins, P. Territo, Mingzhang Gao, 2017, The Journal of Nuclear Medicine.

The first synthesis of [(11)C]SB-216763, a new potential PET agent for imaging of glycogen synthase kinase-3 (GSK-3).

G. Hutchins, G. Sledge, K. Miller, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and biodistribution of new radiolabeled high-affinity choline transporter inhibitors [11C]hemicholinium-3 and [18F]hemicholinium-3.

G. Hutchins, D. Zipes, T. DeGrado, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of carbon-11-labeled casimiroin analogues as new potential PET agents for imaging of quinone reductase 2 and aromatase expression in breast cancer

G. Hutchins, G. Sledge, K. Miller, 2010, Steroids.

Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer.

G. Sledge, K. Miller, Mingzhang Gao, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of carbon-11-labeled isonicotinamides as new potential PET agents for imaging of GSK-3 enzyme in Alzheimer's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2017, Bioorganic & medicinal chemistry letters.

Synthesis of carbon-11-labeled 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine derivatives as new potential PET tracers for imaging of p38α mitogen-activated protein kinase.

Mingzhang Gao, Min Wang, Q. Zheng, 2014, Bioorganic & medicinal chemistry letters.

The first design and synthesis of [11C]MKC-1 ([11C]Ro 31-7453), a new potential PET cancer imaging agent.

G. Hutchins, G. Sledge, K. Miller, 2010, Nuclear medicine and biology.

Synthesis and in vitro biological evaluation of new P2X7R radioligands [11C]halo-GSK1482160 analogs.

G. Hutchins, P. Territo, Mingzhang Gao, 2019, Bioorganic & medicinal chemistry letters.

Synthesis and initial in vitro characterization of a new P2X7R radioligand [18F]IUR-1602.

G. Hutchins, M. Green, P. Territo, 2019, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis and preliminary biological evaluation of a novel P2X7R radioligand [18F]IUR-1601.

G. Hutchins, M. Green, P. Territo, 2018, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro biological evaluation of carbon-11-labeled quinoline derivatives as new candidate PET radioligands for cannabinoid CB2 receptor imaging.

G. Hutchins, K. Miller, Mingzhang Gao, 2010, Bioorganic & medicinal chemistry.

Fully automated synthesis and initial PET evaluation of [11C]PBR28.

A. Saykin, G. Hutchins, Xiao-Ming Xu, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and preliminary biological evaluation of [11C]methyl (2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimidin-7-yl)-d-leucinate for the fractalkine receptor (CX3CR1).

G. Hutchins, P. Territo, Mingzhang Gao, 2017, Bioorganic & medicinal chemistry letters.

Synthesis of a PET tau tracer [(11)C]PBB3 for imaging of Alzheimer's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2015, Bioorganic & medicinal chemistry letters.

Synthesis of carbon-11 labeled 1-(3,4-dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium derivatives as new potential PET SKCa channel imaging agents.

Mingzhang Gao, Min Wang, Q. Zheng, 2008, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of a new fluorine-18-labeled bexarotene analogue for PET imaging of retinoid X receptor.

Mingzhang Gao, Min Wang, Q. Zheng, 2014, Bioorganic & medicinal chemistry letters.

Synthesis of carbon-11 labeled celecoxib derivatives as new candidate PET radioligands for imaging of inflammation.

G. Hutchins, K. Miller, Mingzhang Gao, 2009, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of carbon-11-labeled CK1 inhibitors as new potential PET radiotracers for imaging of Alzheimer's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2018, Bioorganic & medicinal chemistry letters.

Synthesis of [11C]CX-6258 as a new PET tracer for imaging of Pim kinases in cancer.

Mingzhang Gao, Min Wang, Q. Zheng, 2015, Bioorganic & medicinal chemistry letters.

[11C]enzastaurin, the first design and radiosynthesis of a new potential PET agent for imaging of protein kinase C.

G. Sledge, Lu Xu, K. Miller, 2011, Bioorganic & medicinal chemistry letters.

Synthesis of 2,6-difluoro-N-(3-[11C]methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide as a new potential PET agent for imaging of B-Raf(V600E) in cancers.

K. Miller, Mingzhang Gao, Min Wang, 2013, Bioorganic & medicinal chemistry letters.

[11C]GSK2126458 and [18F]GSK2126458, the first radiosynthesis of new potential PET agents for imaging of PI3K and mTOR in cancers.

G. Sledge, K. Miller, Mingzhang Gao, 2012, Bioorganic & medicinal chemistry letters.

[11C]olanzapine, radiosynthesis and lipophilicity of a new potential PET 5-HT2 and D2 receptor radioligand.

Mingzhang Gao, Min Wang, Q. Zheng, 2013, Bioorganic & medicinal chemistry letters.

A new facile synthetic route to [11C]GSK189254, a selective PET radioligand for imaging of CNS histamine H3 receptor.

G. Hutchins, A. Shekhar, Mingzhang Gao, 2012, Bioorganic & medicinal chemistry letters.

A new high-yield synthetic route to PET CB1 radioligands [11C]OMAR and its analogs.

Mingzhang Gao, Min Wang, Q. Zheng, 2012, Bioorganic & medicinal chemistry letters.

Synthesis of [(11)C]GSK1482160 as a new PET agent for targeting P2X(7) receptor.

G. Hutchins, M. Green, Mingzhang Gao, 2015, Bioorganic & medicinal chemistry letters.

Development, validation and implementation of radio-HPLC methods for the P2X7-receptor-targeted [11C]GSK1482160 radiopharmaceutical.

M. Green, Mingzhang Gao, Min Wang, 2018, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis and preliminary biological evaluation of radiolabeled 5-BDBD analogs as new candidate PET radioligands for P2X4 receptor.

G. Hutchins, P. Territo, Mingzhang Gao, 2017, Bioorganic & medicinal chemistry.

Synthesis of [(11)C]MK-1064 as a new PET radioligand for imaging of orexin-2 receptor.

Mingzhang Gao, Min Wang, Q. Zheng, 2016, Bioorganic & medicinal chemistry letters.

Synthesis of carbon-11-labeled imidazopyridine- and purine-thioacetamide derivatives as new potential PET tracers for imaging of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1).

Mingzhang Gao, Min Wang, Q. Zheng, 2016, Bioorganic & medicinal chemistry letters.

Development, validation and implementation of radio-HPLC methods for the P2X7-receptor-targeted [C]GSK1482160 radiopharmaceutical

M. Green, Mingzhang Gao, Min Wang, 2016 .

Fully automated synthesis of [(18)F]T807, a PET tau tracer for Alzheimer's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2014, Bioorganic & medicinal chemistry letters.

An improved synthesis of dopamine D2/D3 receptor radioligands [11C]fallypride and [18F]fallypride.

G. Hutchins, K. Yoder, Mingzhang Gao, 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of new carbon-11-labeled carboxamide derivatives as potential PET dopamine D3 receptor radioligands.

G. Hutchins, Mingzhang Gao, Min Wang, 2008, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of radiolabeled protein disulfide isomerase (PDI) inhibitors as new potential PET agents for imaging of the enzyme PDI in neurological disorders and cancer.

G. Sledge, K. Miller, Mingzhang Gao, 2013, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Facile and high-yield synthesis of N-(4-diethylamino)benzyl-4-[¹¹C]methoxy-N-(p-tolyl)benzenesulfonamide as a new potential PET selective CB2 radioligand.

Mingzhang Gao, Min Wang, Q. Zheng, 2014, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Radiosynthesis of New Carbon-11-labeled Nimesulide Analogs as Potential PET SAER Tracers for Imaging of Aromatase Expression in Breast Cancer

G. Hutchins, G. Sledge, K. Miller, 2010 .

Synthesis of new carbon-11 labeled naphthalene-sulfonamides for PET imaging of human CCR8.

G. Hutchins, G. Sledge, K. Miller, 2008, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of new carbon-11 labeled benzoxazole derivatives for PET imaging of 5-HT(3) receptor.

G. Hutchins, Mingzhang Gao, Min Wang, 2008, European journal of medicinal chemistry.

Synthesis of carbon-11 labeled fluorinated 2-arylbenzothiazoles as novel potential PET cancer imaging agents.

G. Hutchins, G. Sledge, K. Miller, 2006, Bioorganic & medicinal chemistry.

Synthesis of carbon-11-labeled 4-aryl-4H-chromens as new PET agents for imaging of apoptosis in cancer.

G. Hutchins, K. Miller, Mingzhang Gao, 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of new carbon‐11‐labeled 7‐aroyl‐aminoindoline‐1‐sulfonamides as potential PET agents for imaging of tubulin polymerization in cancers

G. Hutchins, G. Sledge, K. Miller, 2008 .

Synthesis of [11C]FEDAA1106 as a new PET imaging probe of peripheral benzodiazepine receptor expression.

G. Hutchins, Mingzhang Gao, Min Wang, 2009, European journal of medicinal chemistry.

Fully automated synthesis of PET TSPO radioligands [11C]DAA1106 and [18F]FEDAA1106.

Mingzhang Gao, Min Wang, Q. Zheng, 2012, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of carbon-11 and fluorine-18 labeled N-acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives as new potential PET AMPA receptor ligands.

A. Clearfield, Mingzhang Gao, Q. Zheng, 2006, Bioorganic & medicinal chemistry letters.

Simple synthesis of carbon-11-labeled chromen-4-one derivatives as new potential PET agents for imaging of DNA-dependent protein kinase (DNA-PK) in cancer.

K. Miller, Mingzhang Gao, Min Wang, 2012, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Facile radiosynthesis of new carbon-11-labeled propanamide derivatives as selective androgen receptor modulator (SARM) radioligands for prostate cancer imaging

K. Miller, Mingzhang Gao, Min Wang, 2011, Steroids.

Synthesis and preliminary in vitro biological evaluation of new carbon-11-labeled celecoxib derivatives as candidate PET tracers for imaging of COX-2 expression in cancer.

K. Miller, Mingzhang Gao, Min Wang, 2011, European journal of medicinal chemistry.

Evaluation of [11C]hemicholinium-15 and [18F]hemicholinium-15 as new potential PET tracers for the high-affinity choline uptake system in the heart.

G. Hutchins, D. Zipes, T. DeGrado, 2007, Bioorganic & Medicinal Chemistry.

Synthesis and preliminary biological evaluation of new carbon-11 labeled tetrahydroisoquinoline derivatives as SERM radioligands for PET imaging of ER expression in breast cancer.

Min Wang, Qi-Huang Zheng, G. Sledge, 2008, European journal of medicinal chemistry.

Synthesis of a New Carbon-11–Labeled Sulfamate Derivative as a Potential PET Tracer for Imaging of Breast Cancer Aromatase and Steroid Sulfatase Expression

K. Miller, Mingzhang Gao, Min Wang, 2011 .

Design and synthesis of carbon-11-labeled dual aromatase–steroid sulfatase inhibitors as new potential PET agents for imaging of aromatase and steroid sulfatase expression in breast cancer

G. Hutchins, G. Sledge, K. Miller, 2009, Steroids.

Simple synthesis of new carbon-11-labeled 1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives for PET imaging of A₃ adenosine receptor.

Mingzhang Gao, Min Wang, Q. Zheng, 2014, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Facile synthesis of new carbon-11 labeled conformationally restricted rivastigmine analogues as potential PET agents for imaging AChE and BChE enzymes.

Mingzhang Gao, Min Wang, Q. Zheng, 2008, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Synthesis of carbon-11 labeled biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues as new potential PET glioma tumor imaging agents.

G. Sledge, K. Miller, Mingzhang Gao, 2007, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Radiosynthesis of carbon-11-labeled camptothecin derivatives as potential positron emission tomography tracers for imaging of topoisomerase I in cancers.

G. Sledge, K. Miller, Mingzhang Gao, 2005, Bioorganic & medicinal chemistry letters.

Synthesis and initial PET imaging of new potential NK1 receptor radioligands 1-[2-(3,5-bis-trifluoromethyl-benzyloxy)-1-phenyl-ethyl]-4-[11C]methyl-piperazine and {4-[2-(3,5-bis-trifluoromethyl-benzyloxy)-1-phenyl-ethyl]-piperazine-1-yl}-acetic acid [11C]methyl ester.

Gary D Hutchins, Qi-Huang Zheng, G. Hutchins, 2005, Nuclear medicine and biology.

Synthesis of radiolabeled stilbene derivatives as new potential PET probes for aryl hydrocarbon receptor in cancers.

G. Hutchins, G. Sledge, K. Miller, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and initial PET imaging of new potential dopamine D3 receptor radioligands (E)-4,3,2-[11C]methoxy-N-4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl-cinnamoylamides.

G. Hutchins, Mingzhang Gao, Q. Zheng, 2005, Bioorganic & medicinal chemistry.

Synthesis of carbon-11-labeled bivalent β-carbolines as new PET agents for imaging of cholinesterase in Alzheimer's disease.

G. Hutchins, Mingzhang Gao, Min Wang, 2011, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[(11)C]Dimebon, radiosynthesis and lipophilicity of a new potential PET agent for imaging of Alzheimer's disease and Huntington's disease.

G. Hutchins, Mingzhang Gao, Min Wang, 2010, Bioorganic & medicinal chemistry letters.

Synthesis of 2-[11C]methoxy-3,17β-O,O-bis(sulfamoyl)estradiol as a new potential PET agent for imaging of steroid sulfatase (STS) in cancers

G. Sledge, Lu Xu, K. Miller, 2012, Steroids.

Synthesis of [11C]PBR06 and [18F]PBR06 as agents for positron emission tomographic (PET) imaging of the translocator protein (TSPO)

K. Miller, Mingzhang Gao, Min Wang, 2011, Steroids.

Synthesis of carbon-11-labeled tricyclic necroptosis inhibitors as new potential PET agents for imaging of tumor necrosis factor alpha (TNF-alpha).

G. Hutchins, G. Sledge, K. Miller, 2010, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Radiosynthesis of [11C]Vandetanib and [11C]chloro-Vandetanib as new potential PET agents for imaging of VEGFR in cancer.

G. Sledge, K. Miller, Mingzhang Gao, 2011, Bioorganic & medicinal chemistry letters.

Synthesis of [11C]GSK1482160 as a new PET agent for targeting P2X7 receptor

G. Hutchins, M. Green, Mingzhang Gao, 2015 .

Simple synthesis of carbon-11 labeled styryl dyes as new potential PET RNA-specific, living cell imaging probes.

G. Hutchins, G. Sledge, K. Miller, 2009, European journal of medicinal chemistry.

Synthesis of [11C]HG-10-102-01 as a new potential PET agent for imaging of LRRK2 enzyme in Parkinson's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2017, Bioorganic & medicinal chemistry letters.

Synthesis of carbon-11-labeled CK1 inhibitors as new potential PET radiotracers for imaging of Alzheimer's disease.

Mingzhang Gao, Min Wang, Q. Zheng, 2018, Bioorganic & medicinal chemistry letters.

Characterization of 11C-GSK1482160 for Targeting the P2X7 Receptor as a Biomarker for Neuroinflammation

G. Hutchins, P. Territo, Mingzhang Gao, 2017, The Journal of Nuclear Medicine.

Synthesis of N-(3-(4-[11C]methylpiperazin-1-yl)-1-(5-methylpyridin-2-yl)-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide as a new potential PET agent for imaging of IRAK4 enzyme in neuroinflammation.

Mingzhang Gao, Min Wang, Q. Zheng, 2018, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Facile synthesis of carbon-11-labeled arylpiperazinylthioalkyl derivatives as new PET radioligands for imaging of 5-HT1AR.

Mingzhang Gao, Min Wang, Q. Zheng, 2012, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.