K. Nepali

发表

Benzoflavones as cholesterol esterase inhibitors: Synthesis, biological evaluation and docking studies.

M. Gupta, Palwinder Singh, J. Singh, 2017, Bioorganic & medicinal chemistry letters.

Rational Approaches, Design Strategies, Structure Activity Relationship and Mechanistic Insights for Anticancer Hybrids

P. Bedi, Sahil Sharma, K. Nepali, 2014 .

Evaluation of antiasthmatic activity of 7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one in combination with ambroxol in Guinea pigs

K. Nepali, R. Goyal, K. L. Dhar, 2011, Medicinal Chemistry Research.

Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes.

Raj Kumar, S. Arora, R. Murthy, 2012, International journal of pharmaceutics.

Possible Involvement of PPAR-γ in the Anticonvulsant Effect of Aegle marmelos (L.) Correa

Jatinder Singh, M. Ishar, K. Nepali, 2013, Neurochemical Research.

Ring-opened tetrahydro-γ-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms.

J. Liou, K. Nepali, Hsueh-Yun Lee, 2017, European journal of medicinal chemistry.

Purine Analogues as Kinase Inhibitors: A Review.

Samir Mehndiratta, P. Bedi, Sahil Sharma, 2015, Recent patents on anti-cancer drug discovery.

Synthesis, screening and docking of fused pyrano[3,2-d]pyrimidine derivatives as xanthine oxidase inhibitor.

M. Gupta, J. Singh, Harbinder Singh, 2017, European journal of medicinal chemistry.

Synthesis and evaluation of naphthoflavones as a new class of non purine xanthine oxidase inhibitors.

M. Gupta, Harbinder Singh, P. Bedi, 2014, Bioorganic & medicinal chemistry letters.

N-(1,3-Diaryl-3-oxopropyl)amides as a new template for xanthine oxidase inhibitors.

Raj Kumar, U. Banerjee, S. Sapra, 2011, Bioorganic & medicinal chemistry.

A rational approach for the design and synthesis of 1-acetyl-3,5-diaryl-4,5-dihydro(1H)pyrazoles as a new class of potential non-purine xanthine oxidase inhibitors.

Raj Kumar, U. Banerjee, S. Sapra, 2011, Bioorganic & medicinal chemistry.

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC.

S. Pan, Han-Li Huang, Chih-Jou Su, 2018, European journal of medicinal chemistry.

Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive nanocarrier.

Chun-Hsu Pan, S. Guru, Sung-Bau Lee, 2022, European journal of medicinal chemistry.

Early investigational tubulin inhibitors as novel cancer therapeutics

J. Liou, K. Nepali, Hsueh-Yun Lee, 2016, Expert opinion on investigational drugs.

Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal

J. Liou, K. Nepali, Sachin Sharma, 2022, Journal of biomedical science.

Antitussive effects of azepino[2,1-b]quinazolones

A. Garg, S. Sapra, Punita Sharma, 2012, Medicinal Chemistry Research.

2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition.

T. Yeh, J. Liou, Jang-Yang Chang, 2016, Organic & biomolecular chemistry.

Design and Synthesis of Aza‐Flavones as a New Class of Xanthine Oxidase Inhibitors

Sahil Sharma, K. Nepali, P. M. Singh Bedi, 2013, Archiv der Pharmazie.

Protective effect of Grewia asiatica leaves extract in animal models of epilepsy and anxiety

K. Nepali, Atamjit Singh, P. M. Singh Bedi, 2022, Journal of Ayurveda and integrative medicine.

A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling.

Y. Yen, S. Pan, Sung-Bau Lee, 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Vasicine and structurally related quinazolines

Sahil Sharma, K. Nepali, K. L. Dhar, 2012, Medicinal Chemistry Research.

Anti-asthmatic activity of azepino [2, 1-b] quinazolones, synthetic analogues of vasicine, an alkaloid from Adhatoda vasica

A. Nargotra, Rukmankesh Mehra, N. Satti, 2014, Medicinal Chemistry Research.

Colchicine and its various physicochemical and biological aspects

S. Sapra, Sahil Sharma, K. Nepali, 2013, Medicinal Chemistry Research.

Rationally designed donepezil-based hydroxamates modulate Sig-1R and HDAC isoforms to exert anti-glioblastoma effects.

J. Liou, K. Nepali, J. Chuang, 2023, European journal of medicinal chemistry.

Synthesis and biological evaluation of arylidene analogues of Meldrum's acid as a new class of antimalarial and antioxidant agents.

S. Jachak, Raj Kumar, R. Gautam, 2010, Bioorganic & medicinal chemistry.

Chalcone based azacarboline analogues as novel antitubulin agents: design, synthesis, biological evaluation and molecular modelling studies.

A. Saxena, M. Gupta, C. Kaur, 2014, European journal of medicinal chemistry.

Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids.

P. Bedi, Sahil Sharma, K. Nepali, 2014, European journal of medicinal chemistry.

Effect of nitrogen insertion on the antitussive properties of menthol and camphor

Raj Kumar, S. Sapra, K. Nepali, 2012, Medicinal Chemistry Research.

4,6‐Diaryl/heteroarylpyrimidin‐2(1H)‐ones as a New Class of Xanthine Oxidase Inhibitors

Dinesh Kumar, M. Gupta, P. Bedi, 2014, Archiv der Pharmazie.

Screening of a library of 4-aryl/heteroaryl-4H-fused pyrans for xanthine oxidase inhibition: synthesis, biological evaluation and docking studies

R. Kaur, M. Gupta, Samir Mehndiratta, 2015, Medicinal Chemistry Research.

Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors.

Dinesh Kumar, P. Bedi, Sahil Sharma, 2014, Bioorganic & medicinal chemistry letters.

Antitumour, acute toxicity and molecular modeling studies of 4-(pyridin-4-yl)-6-(thiophen-2-yl) pyrimidin-2(1H)-one against Ehrlich ascites carcinoma and sarcoma-180

Dinesh Kumar, D. Mondhe, G. Gupta, 2018, Heliyon.

Antitumour and Acute Toxicity Studies of 4-(pyridin-4-yl)-6-(thiophen-2-yl)pyrimidin-2(1H)-one Against Ehrlich Ascites Carcinoma and Sarcoma-180

Dinesh Kumar, D. Mondhe, G. Gupta, 2018 .

The value of pyrans as anticancer scaffolds in medicinal chemistry

Dinesh Kumar, G. Gupta, Pooja Sharma, 2017 .

Nitro-Group-Containing Drugs.

J. Liou, K. Nepali, Hsueh-Yun Lee, 2018, Journal of medicinal chemistry.

Screening of a library of 4-aryl/heteroaryl-4H-fused pyrans for xanthine oxidase inhibition: synthesis, biological evaluation and docking studies

M. Gupta, Samir Mehndiratta, P. Bedi, 2015, Medicinal Chemistry Research.

Vasicine and structurally related quinazolines

Sahil Sharma, K. Nepali, K. L. Dhar, 2013, Medicinal Chemistry Research.

Benzoflavone derivatives as potent antihyperuricemic agents.

Gurleen Kaur, A. Singh, M. Gupta, 2019, MedChemComm.

Design, synthesis and evaluation of 2,4-diarylpyrano[3,2-c]chromen-5(4H)-one as a new class of non-purine xanthine oxidase inhibitors

Samir Mehndiratta, P. Bedi, Sahil Sharma, 2015, Journal of enzyme inhibition and medicinal chemistry.

Antitussive effects of azepino[2,1-b]quinazolones

A. Garg, S. Sapra, Punita Sharma, 2012, Medicinal Chemistry Research.

Triazole tethered isatin-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies.

A. Saxena, M. Gupta, J. Singh, 2017, Bioorganic & medicinal chemistry letters.

Triazole tethered C5-curcuminoid-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies.

A. Saxena, M. Gupta, Harbinder Singh, 2016, European journal of medicinal chemistry.

Anti-cancer pyrimidines in diverse scaffolds: a review of patent literature.

R. Kaur, Samir Mehndiratta, P. Bedi, 2014, Recent patents on anti-cancer drug discovery.

Anticancer hybrids--a patent survey.

Dinesh Kumar, Sahil Sharma, K. Nepali, 2014, Recent patents on anti-cancer drug discovery.

Synthesis of 1,2,3-triazole tethered bifunctional hybrids by click chemistry and their cytotoxic studies

P. Bedi, Sahil Sharma, K. Nepali, 2012, Medicinal Chemistry Research.

An updated patent review: xanthine oxidase inhibitors for the treatment of hyperuricemia and gout (2011-2015)

Harbinder Singh, Sahil Sharma, K. Nepali, 2017, Expert opinion on therapeutic patents.

Synthesis and biological evaluation of naphthalene, furan and pyrrole based chalcones as cytotoxic and antimicrobial agents

A. Garg, S. Sapra, K. Nepali, 2012, Medicinal Chemistry Research.

Naphthoflavones as Antiproliferative Agents: Design, Synthesis and Biological Evaluation.

Dinesh Kumar, Onkar Singh, Shashank K Singh, 2016, Anti-cancer agents in medicinal chemistry.

Steering the antitumor drug discovery campaign towards structurally diverse indolines.

K. Nepali, N. Kaur, Ritu Ojha, 2019, Bioorganic chemistry.

Novel indole-bearing combretastatin analogues as tubulin polymerization inhibitors

P. R. Sharma, A. Saxena, M. Gupta, 2013, Organic and medicinal chemistry letters.

Ocular Disease Therapeutics: Design and Delivery of Drugs for Diseases of the Eye.

J. Liou, K. Nepali, Chien-Ming Hsieh, 2020, Journal of medicinal chemistry.

Estimation of Seasonal Variation of Two Major Pyrrolo [2,1-b] Quinazoline Alkaloids of Adhatoda vasica by HPLC

G. Kaur, Shilpi Aggarwal, K. Nepali, 2013 .

FORMULATION AND EVALUATION OF DICLOFENAC SODIUM GEL BY USING NATURAL POLYMER.

V. Saini, A. Garg, K. Nepali, 2008 .

Antimicrobial and Cytotoxic Activities of Fungal Isolates of Medicinal Plant Gloriosa superba

K. Nepali, K. L. Dhar, A. Budhiraja, 2012 .

Meet the Editorial Board Member

K. Nepali, 2022, Mini-Reviews in Medicinal Chemistry.

Anti-asthmatic activity of azepino [2, 1-b] quinazolones, synthetic analogues of vasicine, an alkaloid from Adhatoda vasica

A. Nargotra, Rukmankesh Mehra, N. Satti, 2014, Medicinal Chemistry Research.

Synthesis and biological evaluation of naphthalene, furan and pyrrole based chalcones as cytotoxic and antimicrobial agents

A. Garg, S. Sapra, M. Kaur, 2012, Medicinal Chemistry Research.

Idiopathic Pulmonary Fibrosis: Current Status, Recent Progress, and Emerging Targets.

J. Liou, K. Nepali, Yi-Min Liu, 2017, Journal of medicinal chemistry.

Design strategies, structure activity relationship and mechanistic insights for purines as kinase inhibitors.

M. Kaur, Harbinder Singh, P. Bedi, 2016, European journal of medicinal chemistry.

Glioblastoma: Current Status, Emerging Targets, and Recent Advances

B. Malik, J. Liou, K. Nepali, 2022, Journal of medicinal chemistry.

Colchicine and its various physicochemical and biological aspects

S. Sapra, Sahil Sharma, K. Nepali, 2012, Medicinal Chemistry Research.

Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends

J. Liou, K. Nepali, Kunal Nepali, 2021, Journal of Biomedical Science.

Bioactive metabolites from an endophytic fungus of Aspergillus species isolated from seeds of Gloriosa superba Linn.

Sanjay Kumar, S. Sapra, K. Nepali, 2012, Medicinal Chemistry Research.

Hydroxamic acids as potent antioxidants and their methods of evaluation

Samir Mehndiratta, K. Nepali, M. K. Satapathy, 2017 .

Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo.

S. Pan, Han-Li Huang, J. Liou, 2020, European journal of medicinal chemistry.

Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells.

S. Pan, J. Liou, Min-Wu Chao, 2019, Bioorganic chemistry.

Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma.

J. Liou, K. Nepali, K. Hsu, 2021, European journal of medicinal chemistry.

Effect of ring A and ring B substitution on the cytotoxic potential of pyrazole tethered chalcones

A. Garg, P. Bedi, K. Nepali, 2012, Medicinal Chemistry Research.

Quinazolines as Apoptosis Inducers and Inhibitors: A Review of Patent Literature.

S. Sapra, Samir Mehndiratta, Manwinder Singh, 2016, Recent Patents on Anti-Cancer Drug Discovery.

The HDAC/HSP90 Inhibitor G570 Attenuated Blue Light-Induced Cell Migration in RPE Cells and Neovascularization in Mice through Decreased VEGF Production

K. Nepali, G. Hsiao, Chi‐Hao Tsai, 2021, Molecules.

Purine/purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors.

Y. Yen, Sung-Bau Lee, J. Liou, 2020, European journal of medicinal chemistry.

Evaluation of antiasthmatic activity of 7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one in combination with ambroxol in Guinea pigs

K. Nepali, R. Goyal, K. L. Dhar, 2011, Medicinal Chemistry Research.

Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent.

S. Pan, J. Liou, K. Nepali, 2021, Journal of medicinal chemistry.

Synthesis and Biological Evaluation of Chalcones having Heterosubstituent(s)

Sweety, A. Saxena, S. Sapra, 2010, Indian journal of pharmaceutical sciences.

Analysis of Mentha waste products using gc- ms.

Raj Kumar, S. Sapra, K. Nepali, 2010 .

(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo.

Chia-Ron Yang, J. Liou, K. Nepali, 2018, Journal of medicinal chemistry.

Synthesis and cytotoxicity studies of 3,5-diaryl N-acetyl pyrazoline—isatin hybrids

A. Saxena, P. Bedi, Sahil Sharma, 2014, Medicinal Chemistry Research.

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase.

J. Liou, Jang-Yang Chang, K. Nepali, 2019, European journal of medicinal chemistry.

Synthesis of 1,2,3-triazole tethered bifunctional hybrids by click chemistry and their cytotoxic studies

A. Saxena, P. Bedi, Sahil Sharma, 2013, Medicinal Chemistry Research.

Correction: Benzoflavone derivatives as potent antihyperuricemic agents

Gurleen Kaur, A. Singh, M. Gupta, 2019, MedChemComm.

Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment.

L. Chan, T. Yeh, J. Liou, 2019, European journal of medicinal chemistry.

Tubulin inhibitors: a patent survey.

P. Bedi, Sahil Sharma, K. Nepali, 2014, Recent patents on anti-cancer drug discovery.

Possible Involvement of PPAR-γ in the Anticonvulsant Effect of Aegle marmelos (L.) Correa

M. Ishar, K. Nepali, R. Bhatti, 2013, Neurochemical Research.

Prudent tactics to sail the boat of PARP inhibitors as therapeutics for diverse malignancies

Sung-Bau Lee, J. Liou, K. Nepali, 2023, Expert opinion on drug discovery.

4,6-diaryl Pyrimidones as Constrained Chalcone Analogues: Design, Synthesis and Evaluation as Antiproliferative Agents.

Dinesh Kumar, F. Malik, S. Jain, 2015, Anti-cancer agents in medicinal chemistry.

Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors.

Dinesh Kumar, P. Bedi, Sahil Sharma, 2014, Bioorganic & medicinal chemistry letters.

Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity relationship.

K. Nepali, Amandeep Thakur, Mandeep Rana, 2023, Bioorganic chemistry.

FORMULATION AND EVALUATION OF LANSOPRAZOLE NIOSOME

V. Saini, A. Garg, K. Nepali, 2008 .

Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress.

K. Nepali, Wen-Bin Yang, Mei-Jung Lai, 2024, Cancer letters.

Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.

K. Nepali, Amandeep Thakur, Mandeep Rana, 2024, European journal of medicinal chemistry.

Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer

S. Guru, A. Dhingra, K. Nepali, 2023, Journal of enzyme inhibition and medicinal chemistry.

Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation.

K. Nepali, A. Grewal, Aman Thakur, 2024, European journal of medicinal chemistry.

European Journal of Medicinal Chemistry Rationally Designed Febuxostat-Based Hydroxamic Acid and its pH-Responsive Nanoformulation Elicits Anti-Tumor Activity

K. Nepali, Ram Sharma, Gurpreet Singh, 2024, European Journal of Medicinal Chemistry.