G. Lin

发表

Molecular docking of different inhibitors and activators to butyrylcholinesterase

S. Chiou, Tzu-Ting Weng, Gin-Zen Lin, 2015, Journal of biomolecular structure & dynamics.

Synthesis and evaluation of a new series of tri‐, di‐, and mono‐N‐alkylcarbamylphloroglucinols as conformationally constrained inhibitors of cholesterol esterase

James Lin, Gin-Zen Lin, Shuo-Yung Jian, 2012, Protein science : a publication of the Protein Society.

Kinetics and Protein‐Inhibitor Docking Studies of Enantiomers of exo‐2‐Norbornyl‐N‐n‐butylcarbamates as Pseudomonas Lipase Inhibitors to Probe the Enantioselectivity of the Enzyme

G. Lin, Yu-fang Shen, 2012 .

Stereo‐specific inhibition of acetyl‐ and butyryl‐cholinesterases by enantiomers of cis,cis‐decahydro‐2‐naphthyl‐N‐n‐butylcarbamate

G. Lin, Ming-cheng Lin, Shyh-Jei Yeh, 2011, Journal of biochemical and molecular toxicology.

Stereoselective Inhibition of Cholesterol Esterase by Enantiomers of exo- and endo-2-Norbornyl-N–n-butylcarbamates

G. Lin, Ming-cheng Lin, Shyh-Jei Yeh, 2011, The protein journal.

Stereoselective inhibition of butyrylcholinesterase by enantiomers of exo- and endo-2-norbornyl-N-n-butylcarbamates

S. Chiou, G. Lin, I-Ru Chen, 2010, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of enantiomers of exo-2-norbornyl-N-n-butylcarbamate and endo-2-norbornyl-N-n-butylcarbamate for stereoselective inhibition of acetylcholinesterase.

S. Chiou, G. Lin, Shyh-Jei Yeh, 2009, Chirality.

QSAR for Inhibition of Pseudomonas Species Lipase by 1‐Acyloxy‐3‐N‐n‐octylcarbamyl‐benzenes

S. Chiou, G. Lin, G. Yu, 2009 .

Benzene-di-N-Substituted Carbamates as Conformationally Constrained Substrate Analogs of Cholesterol Esterase

S. Chiou, G. Lin, M. Lin, 2008, The protein journal.

Activation Mechanisms for Pseudomonas Species Lipase by Cardiovascular Drugs in Vitro

G. Lin, Ming-cheng Lin, G. Lai, 2007 .

Inhibition or activation of Pseudomonas species lipase by 1,2-ethylene-di-N-alkylcarbamates in detergents.

Chun-ping Lu, Yan-Fu Lin, G. Lin, 2007, Chemistry and physics of lipids.

Benzene‐di‐N‐substituted carbamates as conformationally constrained analogs of Pseudomonas lipase substrates

G. Lin, Ming-cheng Lin, M. Hwang, 2007 .

Probing conformations of the glycerol backbones of triacyglycerols in the active site of lipase by 1,2-cyclopentane-carbamates: The meso effect for the enzyme inhibition

G. Lin, Hou-Jen Tsai, Fu-Hwey Lai, 2006 .

Kinetics and quantitative structure-activity relationships for pseudomonas sp. Lipase-catalyzed hydrolysis of both monoesters and diesters of ethylene glycol

Chun-ping Lu, Yan-Fu Lin, S. Chiou, 2006 .

Quantitative Structure-Activity Relationships for the Pre-Steady State of Pseudomonas Species Lipase Inhibitions by p-Nirophenyl-N-Substituted Carbamates

G. Lin, Wei-Cheng Liao, Zuzana Ku, 2005, The protein journal.

Ortho Effects in Quantitative Structure Activity Relationships for Lipase Inhibition by Aryl Carbamates

G. Lin, Yue Liu, Yon-Gi Wu, 2003 .

Conformational Analysis of 1,2‐Di‐O‐Octanoyl‐Ethylene‐Glycerol During Aggregation

Chun-ping Lu, G. Lin, 2000 .

Quantitative structure‐activity relationships for the pre‐steady state acetylcholinesterase inhibition by carbamates

G. Lin, Hou-Jen Tsai, C. Hsieh, 2005, Journal of biochemical and molecular toxicology.

Structure-Reactivity Relationships as Probes to Acetylcholinesterase Inhibition Mechanisms by Aryl Carbamates. II. Hammett-Taft Cross-Interaction Correlations†

G. Lin, 2004 .

Synthesis of Aryl α,α‐Difluoroalkyl Ketones as Potent Inhibitors of Cholesterol Esterase

G. Lin, Fang‐Chen Wu, Hsiao-chien Liu, 1994 .

Enantiomeric inhibitors of cholesterol esterase and acetylcholinesterase.

C. Chang, G. Lin, Y. Tsai, 1998, Biochimica et biophysica acta.

Epoxy Type Inhibitors of Cholesterol Esterase, Acetylcholinesterase, and Butyrylcholinesterase

G. Lin, Bing-Hong Kao, 2000 .

Molecular modeling and docking calculations of 4-acyloxy-biphenyl-4′-N-butylcarbamates as potential inhibitors of human butyrylcholinesterase

G. Lin, Yu-fang Shen, Gan-Hong Chen, 2016 .

Hammett-Taft cross-interaction correlations for the inhibition mechanism of cholesterol esterase by substituted phenyl N-substituted carbamates

G. Lin, 2000 .

Linear free energy relationships of the inhibition of pancreatic cholesterol esterase by 4-Nitrophenyl-N-alkylcarbamate

G. Lin, Cheng-Yue Lai, 1996 .

Hammett analysis of the inhibition of pancreatic cholesterol esterase by substituted phenyl-N-butylcarbamate

G. Lin, Cheng-Yue Lai, 1995 .

THE ENHANCEMENT OF ENANTIOSELECTIVITIES FOR LIPASE-CATALYZED REACTIONS BY USING CARBAMATES

G. Lin, Wen-Yuan Lin, C. Shieh, 1998 .

Microwave-promoted lipase-catalyzed reactions

G. Lin, Wen-Yuan Lin, 1998 .

Azeotropic Distillation‐ and Ultrasound‐Promoted Lipase‐Catalyzed Reactions

G. Lin, Hsiao-chien Liu, Shih-Huang Liu, 1995 .

Ultrasound-promoted lipase-catalyzed reactions

G. Lin, Hsiao-chien Liu, 1995 .

Multiple Enantioselection by an Enzyme-Catalyzed Transacylation Reaction

G. Lin, Show‐Jane Chen, H. Sun, 1994 .

Phospholipase A2-Catalyzed Hydrolysis of 1,2-DimyristoyI-sn-Glycero-3-Phosphocholine in Organic Solvents

G. Lin, Fang‐Chen Wu, 1994 .

LIPASE-CATALYZED TRANSACYLATION REACTIONS IN AZEOTROPIC DISTILLATION

G. Lin, Shih-Huang Liu, 1993 .

Novel Acyl Donors for Enzyme-Catalyzed Transacylation Reactions

G. Lin, Fang‐Chen Wu, Shih-Huang Liu, 1993 .

Phospholipase A2 catalyses in organic media

G. Lin, Fang‐Chen Wu, Shih-Huang Liu, 1993 .

Phospholipids chiral at phosphorus. Stereochemical mechanism of reactions catalyzed by phosphatidylinositide-specific phospholipase C from Bacillus cereus and guinea pig uterus.

C. F. Bennett, M. Tsai, G. Lin, 1990, Biochemistry.

Activation Mechanisms of Butyrylcholinesterase by 2,4,6-Trinitrotoluene, 3,3-Dimethylbutyl-N-n-butylcarbamate, and 2-Trimethylsilyl-ethyl-N-n-butylcarbamate

S. Chiou, G. Lin, Yon-Gi Wu, 2008, Applied biochemistry and biotechnology.

Substrate activation of butyrylcholinesterase and substrate inhibition of acetylcholinesterase by 3,3‐dimethylbutyl‐N‐n‐butylcarbamate and 2‐trimethylsilyl‐ethyl‐N‐n‐butylcarbamate

Yan-Fu Lin, S. Chiou, G. Lin, 2007, Journal of biochemical and molecular toxicology.

1H NMR characterization of a combination model of the mixed micelle taurocholate and 1,2-ethylene-di-N-n-butylcarbamate

Chun-ping Lu, S. Chiou, G. Lin, 2008 .

Conformational Freeze for the Ethylene Glycol Backbone of 1,2-Ethylene-di-N-n-propylcarbamate in the Triton X-100 Mixed Micelle

Chun-ping Lu, S. Chiou, G. Lin, 2008 .

Phospholipids chiral at phosphorus. XVIII: Stereochemistry of phosphatidylinositide-specific phospholipase C

M. Tsai, G. Lin, 1989 .

Conformational Analysis of Biphenyl‐2,2′‐Diacetate

G. Lin, Fang‐Chen Wu, Show‐Jane Chen, 1994 .

“Triple Enantioselection” by an Enzyme‐Catalyzed Transacylation Reaction.

Shimou Chen, G. Lin, Fang‐Chen Wu, 1994 .

Quantitative structure-activity relationships for the pre-steady-state inhibition of cholesterol esterase by 4-nitrophenyl-N-substituted carbamates.

S. Chiou, G. Lin, W. Liao, 2000, Bioorganic & medicinal chemistry.

Qsar for Acetylcholinesterase and Butyrylcholinesterase Inhibition by Cardiovascular Drugs and Benzodiazepines

S. Chiou, G. Lin, G. Lai, 2005, Medicinal Chemistry Research.

Ortho effects and cross interaction correlations for the mechanisms of cholesterol esterase inhibition by aryl carbamates

G. Lin, Yu‐Chen Liu, Yon-Gi Wu, 2004 .

Comparison of active sites of butyrylcholinesterase and acetylcholinesterase based on inhibition by geometric isomers of benzene‐di‐N‐substituted carbamates

S. Chiou, G. Lin, Chuan-fu Huang, 2009, Journal of biochemical and molecular toxicology.

Syntheses of 1,2‐Dtpalmitoyl‐Sn‐Glycero‐3‐Phospho‐1′‐myoinositol and 1,2‐Dipalmitoyl‐Sn‐Glycero‐3‐Phosphorothio‐1′‐myoinositol

G. Lin, Fang‐Chen Wu, Shih-Huang Liu, 1993 .

S‐endo‐2‐Norbornyl‐N‐n‐butylcarbamate as a Potential Pseudomonas Lipase Inhibitor to Probe the Enantioselectivity of the Enzyme by Kinetic and Molecular Docking Evaluation

G. Lin, Yu-fang Shen, Gan-Hong Chen, 2016 .

E339…R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors

A. Yang, Chi‐Huey Wong, M. Tsai, 2011, Proceedings of the National Academy of Sciences.

Synthesis and evaluation of a new series of tri-, di-, and mono-N-alkylcarbamylphloroglucinols as bulky inhibitors of acetylcholinesterase.

James Lin, D. Hsieh, Shuo-Yung Jian, 2012, Chemical research in toxicology.

Benzene‐1,2‐, 1,3‐, and 1,4‐di‐N‐substituted carbamates as conformationally constrained inhibitors of acetylcholinesterase

G. Lin, Ming-cheng Lin, M. Hwang, 2007, Journal of biochemical and molecular toxicology.

Probing Structure–Function Relationships of Serine Hydrolases and Proteases with Carbamate and Thiocarbamate Inhibitors

S. Chiou, G. Lin, C. Hsieh, 2006, The protein journal.

QSARs for Peripheral Anionic Site of Butyrylcholinesterase with Inhibitions by 4‐Acyloxy‐biphenyl‐4′‐N‐butylcarbamates

Chun-ping Lu, G. Lin, Chun-Ping Lu, 2005 .

Probing stereoselective inhibition of the acyl binding site of cholesterol esterase with four diastereomers of 2'-N-α-methylbenzylcarbamyl-1, 1'-bi-2-naphthol

S. Chiou, G. Lin, Long-Yau Lin, 2005, BMC Biochemistry.

Probing the peripheral anionic site of acetylcholinesterase with quantitative structure activity relationships for inhibition by biphenyl‐4‐acyoxylate‐4′‐N‐Butylcarbamates

Chun-ping Lu, G. Lin, Chun-Ping Lu, 2005, Journal of biochemical and molecular toxicology.

Kinetics and Mechanisms of Acetylcholinesterase and Butyrylcholinesterase Inhibition by Cardiovascular Drugs and Benzodiazepines

S. Chiou, G. Lin, G. Lai, 2005 .

A rate determining step change in the pre-steady state of acetylcholinesterase inhibitions by 1,n-alkane-di-N-butylcarbamates.

G. Lin, Bo-Yi Tsai, Hsing-Chang Tseng, 2005, Bioorganic & medicinal chemistry letters.

Ortho Effects in Quantitative Structure-activity Relationships for Acetylcholinesterase Inhibition by Aryl Carbamates

Yan-Fu Lin, G. Lin, Yu‐Chen Liu, 2004, Journal of enzyme inhibition and medicinal chemistry.

Structure‐Reactivity Relationships as Probes to Acetylcholinesterase Inhibition Mechanisms by Aryl Carbamates. I. Steady‐State Kinetics

G. Lin, Cheng-Yue Lai, C. Chan, 2003 .

Cage amines as the stopper inhibitors of cholinesterases.

G. Lin, Hou-Jen Tsai, Gialih Lin, 2003, Bioorganic & medicinal chemistry letters.

Molecular recognition by acetylcholinesterase at the peripheral anionic site: structure-activity relationships for inhibitions by aryl carbamates.

C. Lai, G. Lin, C Y Lai, 1999, Bioorganic & medicinal chemistry.

Conformationally restricted carbamate inhibitors of horse serum butyrylcholinesterase.

G. Lin, H. Ho, G. H. Chen, 1998, Bioorganic & medicinal chemistry letters.

Structure-reactivity relationships as probes for the inhibition mechanism of cholesterol esterase by aryl carbamates. I. Steady-state kinetics

Chun-ping Lu, G. Lin, Wei-Cheng Liao, 2000 .

(Bioorganic & Medicinal Chemistry Letters, 14:751-755)Benzene-di-N-octylcarbamates As Conformationally Constrained Phospholipase A2 Inhibitors

Yan-Fu Lin, G. Lin, M. Hwang, 2004 .

Use of short-chain cyclopentano-phosphatidylcholines to probe the mode of activation of phospholipase A2 from bovine pancreas and bee venom.

J. Noel, M. Tsai, G. Lin, 1988, The Journal of biological chemistry.

Conformational Analysis of Biphenyl Derivatives. I. A Novel Steric Constant from the Internal Rotation Rate of 2,2'-Bis-(N-Substituted Carbamoylmethyl)Biphenyl by Means of Dynamic NMR

G. Lin, Hou-Jen Tsai, J. Chouhwang, 2000 .

QSAR for phospholipase A2 inhibitions by 1-acyloxy-3-N-n-octylcarbamyl-benzenes.

G. Lin, G. Yu, 2005, Bioorganic & medicinal chemistry letters.

Benzene-di-N-octylcarbamates as conformationally constrained phospholipase A(2) inhibitors.

Yan-Fu Lin, G. Lin, M. Hwang, 2004, Bioorganic & medicinal chemistry letters.

Structure-reactivity probes for active site shapes of cholesterol esterase by carbamate inhibitors.

G. Lin, Y. Tsai, C. Shieh, 1999, Biochimica et biophysica acta.

Atropisomeric carbamoyl type inhibitors of pancreatic cholesterol esterase

G. Lin, Hsiao-chien Liu, Y. Tsai, 1996 .