V. Gasparik

发表

Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome.

V. Gasparik, H. Greney, S. Schann, 2015, Journal of medicinal chemistry.

Methylation of imidazoline related compounds leads to loss of α₂-adrenoceptor affinity. Synthesis and biological evaluation of selective I₁ imidazoline receptor ligands.

L. Monassier, M. Dontenwill, V. Gasparik, 2012, Bioorganic & medicinal chemistry.

From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G-Protein-Coupled Receptors.

J. Pin, A. Mann, T. Roux, 2018, Journal of medicinal chemistry.

In silico tools and in vitro HTS approaches to determine lipophilicity during the drug discovery process

P. Carrupt, S. Martel, V. Gasparik, 2009 .

Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia.

D. Rognan, Muriel Hachet-Haas, J. Galzi, 2018, Journal of medicinal chemistry.

An Antedrug of the CXCL12 Neutraligand Blocks Experimental Allergic Asthma without Systemic Effect in Mice

Muriel Hachet-Haas, J. Galzi, N. Frossard, 2013, The Journal of Biological Chemistry.

Prodrugs of a CXC Chemokine-12 (CXCL12) Neutraligand Prevent Inflammatory Reactions in an Asthma Model in Vivo.

Muriel Hachet-Haas, J. Galzi, N. Frossard, 2012, ACS medicinal chemistry letters.

3 Redox-sensitive up-regulation of eNOS by purple grape juice in endothelial cells : Role of PI 3-kinase / Akt , p 38 MAPK , JNK , FoxO 1 and FoxO 3 a

N. Tinel, T. Roux, L. Lamarque, 2013 .

Probing the Outstanding Local Hydrophobicity Increases in Peptide Sequences Induced by Incorporation of Trifluoromethylated Amino Acids

V. Gasparik, T. Brigaud, Julien Pytkowicz, 2018, Chembiochem : a European journal of chemical biology.

(R)‐α‐trifluoromethylalanine containing short peptide in the inhibition of amyloid peptide fibrillation

O. Lequin, L. Caillon, V. Gasparik, 2015, Biopolymers.

A New Pyrroline Compound Selective for I1-Imidazoline Receptors Improves Metabolic Syndrome in Rats

C. Julien, P. Lacolley, A. Pizard, 2013, The Journal of Pharmacology and Experimental Therapeutics.

compound selective for I 1-imidazoline receptors improves metabolic syndrome in rats

C. Julien, P. Lacolley, A. Pizard, 2013 .