J. Feldman

发表

Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome.

V. Gasparik, H. Greney, S. Schann, 2015, Journal of medicinal chemistry.

Methylation of imidazoline related compounds leads to loss of α₂-adrenoceptor affinity. Synthesis and biological evaluation of selective I₁ imidazoline receptor ligands.

L. Monassier, M. Dontenwill, V. Gasparik, 2012, Bioorganic & medicinal chemistry.

Drugs Acting on Imidazoline Receptors

J. Feldman, P. Bousquet, 1999, Drugs.

Imidazoline receptors: a challenge.

S. Schann, J. Feldman, P. Bousquet, 2000, Pharmaceutica acta Helvetiae.

Imidazoline receptors in cardiovascular and metabolic diseases.

M. Dontenwill, H. Greney, J. Feldman, 2000, Journal of cardiovascular pharmacology.

Does a second generation of centrally acting antihypertensive drugs really exist?

L. Monassier, M. Dontenwill, H. Greney, 1998, Journal of the autonomic nervous system.

Imidazoline receptor ligands:cardiovascular applications

L. Monassier, J. Feldman, P. Bousquet, 1998 .

Inhibition of centrally induced ventricular arrhythmias by rilmenidine and idazoxan in rabbits

L. Monassier, J. Feldman, P. Bousquet, 1996, Naunyn-Schmiedeberg's Archives of Pharmacology.

An endogenous, non-catecholamine clonidine antagonist increases mean arterial blood pressure.

D. Atlas, J. Feldman, P. Bousquet, 1986, European journal of pharmacology.

Effects of ifenprodil and baclofen on exercise-induced increase of myocardial oxygen demand in normotensive rats.

L. Monassier, J. Feldman, P. Bousquet, 1999, The Journal of pharmacology and experimental therapeutics.

Does It Make Sense To Develop New Centrally Acting Cardiovascular Drugs?

L. Monassier, J. Feldman, P. Bousquet, 2001, Clinical and experimental pharmacology & physiology.

AUTONOMIC NERVOUS SYSTEM AS A TARGET FOR CARDIOVASCULAR DRUGS

L. Monassier, J. Feldman, P. Bousquet, 1998, Clinical and experimental pharmacology & physiology.

Comparative effects of idazoxan, prazosin, and yohimbine on coronary ligation-induced arrhythmias in spontaneously hypertensive rats.

L. Monassier, J. Feldman, P. Bousquet, 1996, Journal of cardiovascular pharmacology.

MK-801 and memantine inhibit a centrally induced increase in myocardial oxygen demand in rabbits.

L. Monassier, J. Feldman, P. Bousquet, 1996, European journal of pharmacology.

Medullary hypotensive effect of endothelin1 in anaesthetized animals

J. Stutzmann, J. Feldman, P. Bousquet, 1994, Fundamental & clinical pharmacology.

G-Protein inwardly rectifying potassium channels are involved in the hypotensive effect of I1-imidazoline receptor selective ligands

D. Urošević, H. Greney, J. Feldman, 2008, Journal of hypertension.

Medullary cardiovascular effects of tetrodotoxin in anaesthetized cats.

J. Schwartz, J. Feldman, P. Bousquet, 1980, European journal of pharmacology.

Role of the ventral surface of the brain stem in the hypotensive action of clonidine.

J. Feldman, P. Bousquet, J. Velly, 1975, European journal of pharmacology.

Central cardiovascular effects of alpha adrenergic drugs: differences between catecholamines and imidazolines.

J. Schwartz, J. Feldman, P. Bousquet, 1984, The Journal of pharmacology and experimental therapeutics.

Protective effects of centrally acting sympathomodulatory drugs on myocardial ischemia induced by sympathetic overactivity in rabbits.

J. Feldman, P. Bousquet, E. Tibirica, 2003, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Pharmacological analysis of the central cardiovascular effects of four GABA analogues

J. Schwartz, J. Feldman, P. Bousquet, 1984, Naunyn-Schmiedeberg's Archives of Pharmacology.

The central hypotensive action of baclofen in the anaesthetized cat.

J. Schwartz, J. Feldman, P. Bousquet, 1981, European journal of pharmacology.

PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version

L. Monassier, H. Greney, S. Schann, 1998 .

An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan.

F. Gonon, J. Feldman, P. Bousquet, 1991, The Journal of pharmacology and experimental therapeutics.

The imidazoline preferring receptor: binding studies in bovine, rat and human brainstem.

M. Dontenwill, G. Bricca, J. Feldman, 1989, European journal of pharmacology.

Evidence for the involvement of imidazoline receptors in the central hypotensive effect of rilmenidine in the rabbit

M. Dontenwill, G. Bricca, J. Feldman, 1990, British journal of pharmacology.

Imidazoline receptors. A new concept in central regulation of the arterial blood pressure.

M. Dontenwill, J. Stutzmann, G. Bricca, 1992, American journal of hypertension.

Imidazolines inhibit catecholaminergic ventrolateral medullary neurons via specific receptors: a voltammetric approach☆

F. Gonon, J. Feldman, P. Bousquet, 1990 .

Differences in the ability of yohimbine to antagonize the hypotensive effect of clonidine in normotensive and spontaneously hypertensive anesthetized rats.

J. Feldman, P. Bousquet, E. Tibirica, 1988, The Journal of pharmacology and experimental therapeutics.

evidence for a neuromodulatory role of GABA at the first synapse of the baroreceptor reflex pathway

J. Schwartz, J. Feldman, P. Bousquet, 1982, Naunyn-Schmiedeberg's Archives of Pharmacology.

New concepts on the central regulation of blood pressure. Alpha 2-adrenoceptors and "imidazoline receptors".

M. Dontenwill, G. Bricca, J. Feldman, 1989, The American journal of medicine.

The effects of ouabain in the medullary site of the hypotensive action of clonidine.

J. Schwartz, J. Feldman, P. Bousquet, 1984, Life sciences.

The nucleus reticularis lateralis: a region highly sensitive to clonidine.

J. Schwartz, J. Feldman, P. Bousquet, 1981, European journal of pharmacology.

Role of imidazoline receptors in cardiovascular regulation.

M. Dontenwill, J. Stutzmann, G. Bricca, 1994, The American journal of cardiology.

Nitric oxide discriminates the sites and mechanisms of action of centrally acting anti-hypertensive drugs in rabbits

J. Feldman, P. Bousquet, V. Bruban, 2002, Neuropharmacology.

Nitric Oxide and Central Antihypertensive Drugs: One More Difference Between Catecholamines and Imidazolines

J. Feldman, P. Bousquet, V. Bruban, 2001, HYPERTENSION.

Synthesis and biological evaluation of pyrrolinic isosteres of rilmenidine. Discovery of cis-/trans-dicyclopropylmethyl-(4,5-dimethyl-4,5-dihydro-3H-pyrrol-2-yl)-amine (LNP 509), an I1 imidazoline receptor selective ligand with hypotensive activity.

P. Renard, B. Pfeiffer, S. Schann, 2001, Journal of medicinal chemistry.

Evidence for a spinal origin of the effect of baclofen on the myocardial oxygen demand indexes

L. Monassier, J. Feldman, P. Bousquet, 1995, Naunyn-Schmiedeberg's Archives of Pharmacology.

Prevention by NMDA receptor antagonists of the centrally‐evoked increases of cardiac inotropic responses in rabbits

L. Monassier, B. Mettauer, J. Feldman, 1994, British journal of pharmacology.

Relationship between the ventromedullary clonidine-sensitive area and the posterior hypothalamus.

J. Schwartz, J. Feldman, P. Bousquet, 1977, European journal of pharmacology.

Selectivity of rilmenidine for the nucleus reticularis lateralis, a ventrolateral medullary structure containing imidazoline-preferring receptors.

F. Gonon, L. Monassier, J. Feldman, 1991, European journal of pharmacology.

Baclofen prevents the increase of myocardial oxygen demand indexes evoked by the hypothalamic stimulation in rabbits

L. Monassier, J. Feldman, P. Bousquet, 1993, Naunyn-Schmiedeberg's Archives of Pharmacology.

The medullary cardiovascular effects of imidazolines and some GABA analogues: a review.

J. Schwartz, J. Feldman, P. Bousquet, 1985, Journal of the autonomic nervous system.

Is the hypotensive effect obtained by application of drugs to the ventral surface of the brain stem due to a membrane stabilizing mechanism? A study with beta-blockers

J. Schwartz, J. Feldman, P. Bousquet, 1978, Neuropharmacology.

1383 – INVOLVEMENT OF THE HYPOTHALAMUS AND THE VENTROLATERAL MEDULLA IN THE CARDIOVASCULAR CONTROL: A STUDY WITH CLONIDINE AND PIPEROXANE

J. Schwartz, J. Feldman, P. Bousquet, 1978 .

Correction: Constitutive Overexpression of Muscarinic Receptors Leads to Vagal Hyperreactivity

N. Dali-Youcef, J. Gies, J. Feldman, 2011, PLoS ONE.

Constitutive Overexpression of Muscarinic Receptors Leads to Vagal Hyperreactivity

N. Dali-Youcef, J. Gies, J. Feldman, 2010, PloS one.

Respective contributions of α‐adrenergic and non‐adrenergic mechanisms in the hypotensive effect of imidazoline‐like drugs

J. Boutin, P. Renard, B. Pfeiffer, 2001, British journal of pharmacology.

Central cardiovascular effects of taurine: comparison with homotaurine and muscimol.

J. Schwartz, J. Feldman, P. Bousquet, 1981, The Journal of pharmacology and experimental therapeutics.

TAG antagonises the central cardiovascular effects of taurine.

J. Schwartz, J. Feldman, P. Bousquet, 1984, European journal of pharmacology.

Imidazoline Receptors and Cardiovascular Regulations

M. Dontenwill, J. Stutzmann, H. Greney, 1995 .

Imidazoline receptors and cardiovascular regulations. A statement.

M. Dontenwill, J. Stutzmann, H. Greney, 1995, Annals of the New York Academy of Sciences.

Immunopurification of a Vasopressive Substance from Human Serum with an Anti‐Clonidine Antibody

M. Dontenwill, G. Bricca, J. Feldman, 1995, Annals of the New York Academy of Sciences.

THE SYMPATHETIC NERVOUS SYSTEM AS A TARGET FOR CARDIOVASCULAR DRUGS: PERSPECTIVES

M. Dontenwill, J. Feldman, P. Bousquet, 1997 .

L 2 ‐ FROM THE α2‐ADRENOCEPTORS TO THE IMIDAZOLINE PREFERRING RECEPTORS

M. Dontenwill, J. Stutzmann, G. Bricca, 1992 .

Contribution of catecholaminergic neurons of the dorsomedial and ventrolateral medulla oblongata to the hypotensive effect of clonidine in spontaneously hypertensive rats: in vivo voltammetric studies.

J. Feldman, P. Bousquet, E. Tibirica, 1992, Journal of Hypertension.

Participation of Imidazoline Receptors and Alpha2−‐Adrenoceptors in the Central Hypotensive Effects of Imidazoline‐Like Drugs

M. Dontenwill, H. Greney, S. Schann, 1999, Annals of the New York Academy of Sciences.

Imidazoline binding sites (IBS) profile modulation: key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues.

L. Brasili, M. Dontenwill, J. Feldman, 2003, Journal of Medicinal Chemistry.

Rilmenidine selectivity for imidazoline receptors in human brain.

M. Dontenwill, G. Bricca, J. Feldman, 1989, European journal of pharmacology.

Evidence for the existence of a homogeneous population of imidazoline receptors in the human brainstem.

M. Dontenwill, G. Bricca, J. Feldman, 1988, European journal of pharmacology.

I1-imidazoline receptors: an update.

M. Dontenwill, H. Greney, J. Feldman, 1998, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

The blood pressure effects of alpha-adrenoceptor antagonists injected in the medullary site of action of clonidine: the nucleus reticularis lateralis.

J. Feldman, P. Bousquet, 1987, Life sciences.

An Unexpected Central Hypertensive Effect of the New Imidazoline Compound Benazoline

L. Brasili, M. Dontenwill, H. Greney, 1999, Annals of the New York Academy of Sciences.

The central hypotensive effect induced by α2-adrenergic receptor stimulation is dependent on endothelial nitric oxide synthase

J. Feldman, L. Fellmann, P. Bousquet, 2008, Journal of hypertension.

Cardiovascular effects of clonidine-like drugs in pithed rabbits.

J. Feldman, P. Bousquet, K. Pompermayer, 1999, Hypertension.

Role of cental alpha2B-adrenergic receptors in blood pressure control and hypertension.

J. Feldman, P. Bousquet, 2003, Journal of hypertension.

Drugs acting on imidazoline receptors: a review of their pharmacology, their use in blood pressure control and their potential interest in cardioprotection.

J. Feldman, P. Bousquet, 1999, Drugs.

Opposite to α2-adrenergic agonists, an imidazoline I1 selective compound does not influence reflex bradycardia in rabbits

J. Feldman, P. Bousquet, G. Sy, 2006, Autonomic Neuroscience.

Evidence for Synergy Between &agr;2-Adrenergic and Nonadrenergic Mechanisms in Central Blood Pressure Regulation

P. Renard, L. Monassier, S. Schann, 2002, Circulation.

Cardiovascular effects of chronic ifenprodil in a model of central sympathetic stimulation

L. Monassier, J. Feldman, E. Tibiriçá, 2000, Fundamental & clinical pharmacology.

GABAergic and glutaminergic modulation of centrally evoked arrhythmias in rats.

L. Monassier, J. Feldman, P. Bousquet, 1996, Hypertension.

Cardiovascular effects of intracerebroventricular injections of baclofen in the conscious rabbit

J. Schwartz, J. Feldman, P. Bousquet, 1982, The Journal of pharmacy and pharmacology.

I1 Imidazoline Receptors Involved in Cardiovascular Regulation: Where Are We and Where Are We Going?

L. Monassier, H. Greney, S. Schann, 2003 .

The imidazoline receptors and the central regulation of the arterial blood pressure: a minireview.

M. Dontenwill, J. Stutzmann, G. Bricca, 1993, Memorias do Instituto Oswaldo Cruz.

The ventromedullary hypotensive effect of muscimol in the anaesthetized cat.

J. Schwartz, J. Feldman, P. Bousquet, 1981, Clinical and experimental hypertension.

I(1) imidazoline receptors involved in cardiovascular regulation: where are we and where are we going?

L. Monassier, H. Greney, S. Schann, 2003, Annals of the New York Academy of Sciences.