L. Cornelius

发表

Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

Ping Chen, A. Doweyko, Derek J. Norris, 2004, Journal of medicinal chemistry.

Discovery of N-isoxazolyl biphenylsulfonamides as potent dual angiotensin II and endothelin A receptor antagonists.

Natesan Murugesan, S. Chong, J. Barrish, 2002, Journal of medicinal chemistry.

DBS sampling can be used to stabilize prodrugs in drug discovery rodent studies without the addition of esterase inhibitors.

T. Olah, L. Cornelius, J. Santella, 2010, Bioanalysis.

Discovery of orally active pyrrolopyridine- and aminopyridine-based Met kinase inhibitors.

J. Fargnoli, J. Tokarski, J. Hunt, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors.

L. Mueller, S. Sheriff, David K. Williams, 2006, Bioorganic & medicinal chemistry letters.

Improved P1/P1' substituents for cyclic urea based HIV-1 protease inhibitors: synthesis, structure-activity relationship, and X-ray crystal structure analysis.

Chong-Hwan Chang, P. Jadhav, L. Bacheler, 1997, Journal of medicinal chemistry.

Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders.

K. McIntyre, Sidney Pitt, G. Schieven, 2017, Journal of medicinal chemistry.

Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent and selective PI3Kδ inhibitors.

C. Weigelt, M. Poss, J. Sack, 2017, Bioorganic & medicinal chemistry letters.

Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily.

J. Fargnoli, J. Tokarski, G. Trainor, 2009, Journal of medicinal chemistry.

Nonsteroidal progesterone receptor ligands. 2. High-affinity ligands with selectivity for bone cell progesterone receptors.

L. Cornelius, J. Gunnet, K. Demarest, 1995, Journal of medicinal chemistry.

A Convenient Synthesis of Mono- and Polyhalogenated Benzocyclanones

L. Cornelius, D. Combs, 1994 .

Neutral acylation (protection) of the indole nitrogen: A simple synthesis of indole-1-carboxylates, indole-1-thiocarboxylates and indole-1-carboxamides

Alison L. Cuff, J. Macor, L. Cornelius, 1999 .

Synthesis of 2-acetylbicyclo[2.2.1]hept-2-ene

M. Deardorff, L. Cornelius, H. W. Pinnick, 1993 .

Photocatalytic Dearomative Intermolecular [2 + 2] Cycloaddition of Heterocycles for Building Molecular Complexity.

Antonio Ramirez, A. Mathur, N. Meanwell, 2020, The Journal of organic chemistry.

Synthesis of Cyclobutane-Fused Tetracyclic Scaffolds via Visible-Light Photocatalysis for Building Molecular Complexity.

Antonio Ramirez, A. Mathur, N. Meanwell, 2020, Journal of the American Chemical Society.

Facile Preparation of 2,6-Disubstituted Purines Using Solid-Phase Chemistry.

L. Cornelius, J. W. Corbett, D. Nugiel, 1997, The Journal of organic chemistry.

Discovery of 4'-[(imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/angiotensin II receptor antagonists.

J. Macor, M. Kowala, M. Valentine, 2003, Bioorganic & medicinal chemistry letters.

Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist.

D. Shuster, J. Macor, C. Weigelt, 2020, ACS medicinal chemistry letters.

Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage.

J. Macor, C. Weigelt, K. Kish, 2019, ACS medicinal chemistry letters.

Kusaiean reference grammar

Elmer Asher, Kee-dong Lee, Lyndon Cornelius, 1975 .