G. J. Correy

发表

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

A. Ashworth, J. Irwin, B. Shoichet, 2020, Science Advances.

Structure-based inhibitor optimization for the Nsp3 Macrodomain of SARS-CoV-2

Yurii S. Moroz, J. Irwin, B. Shoichet, 2022, bioRxiv.

The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature

J. Holton, A. Cohen, J. Fraser, 2022, Science advances.

Total Syntheses of the Amaryllidaceae Alkaloids Zephycandidine III and Lycosinine A and Their Evaluation as Inhibitors of Acetylcholinesterase

C. Jackson, P. Carr, A. Willis, 2017 .

Molecular basis for the behavioral effects of the odorant degrading enzyme Esterase 6 in Drosophila

J. Oakeshott, C. Jackson, Jian-wei Liu, 2017, Scientific Reports.

Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 Macrodomain of SARS-CoV-2

Yurii S. Moroz, J. Irwin, B. Shoichet, 2022, bioRxiv.

The role of protein dynamics in the evolution of new enzyme function.

Benjamin T. Porebski, Ashley M Buckle, Colin J Jackson, 2016, Nature chemical biology.

Overcoming insecticide resistance through computational inhibitor design

C. Jackson, N. London, A. Harmelin, 2017, Proceedings of the National Academy of Sciences of the United States of America.

Maternal and neonatal disposition of pethidine in childbirth--a study using quantitative gas chromatography-mass spectrometry.

M. Finnie, J. Caldwell, B. Lieberman, 1978, Life sciences.

Evolution of Protein Quaternary Structure in Response to Selective Pressure for Increased Thermostability.

J. Oakeshott, M. Perugini, C. Jackson, 2016, Journal of molecular biology.

Conformational Disorganization within the Active Site of a Recently Evolved Organophosphate Hydrolase Limits Its Catalytic Efficiency.

C. Jackson, M. Coote, G. J. Correy, 2016, Biochemistry.

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

A. Ashworth, J. Irwin, B. Shoichet, 2021, Science Advances.

Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography.

C. Jackson, P. Carr, M. Weik, 2016, Structure.

Laboratory evolution of protein conformational dynamics.

Ashley M Buckle, Colin J Jackson, Nobuhiko Tokuriki, 2018, Current opinion in structural biology.

Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2

Yurii S. Moroz, J. Irwin, B. Shoichet, 2023, Proceedings of the National Academy of Sciences of the United States of America.

The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature

A. Ashworth, J. Holton, A. Cohen, 2022, bioRxiv.

A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo

J. Fraser, M. Ott, Morgan E. Diolaiti, 2023, bioRxiv.

Fragment-Based Hit Discovery via Unsupervised Learning of Fragment-Protein Complexes

Alpha A Lee, J. Fraser, N. London, 2022, bioRxiv.

Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

R. Locksley, J. Fraser, M. Thompson, 2023, bioRxiv.

Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

R. Locksley, J. Fraser, M. Thompson, 2023, bioRxiv.

A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo

J. Fraser, M. Ott, Morgan E. Diolaiti, 2023, PLoS pathogens.

Of problems and opportunities—How to treat and how to not treat crystallographic fragment screening data

G. Klebe, A. Heine, J. Fraser, 2022, bioRxiv.

Overcoming insecticide resistance through computational inhibitor design

C. Jackson, N. London, A. Harmelin, 2017, Proceedings of the National Academy of Sciences of the United States of America.

AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid

Adair L. Borges, Morgan E. Diolaiti, G. J. Correy, 2024, bioRxiv.