R. Trilles

发表

Identification of a Small Molecule Inhibitor of the IL-2/IL-2Rα Receptor Interaction Which Binds to IL-2

G. Powers, D. Fry, L. Chen, 1997 .

Organic Synthesis Toward Small-Molecule Probes and Drugs Special Feature: Discovery of new antimalarial chemotypes through chemical methodology and library development

Aaron B. Beeler, X. Su, S. Schaus, 2011 .

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

Christina A. Cuomo, C. Cuomo, L. Cowen, 2020, Nature Communications.

Focused library approach for identification of new N-acylphenylalanines as VCAM/VLA-4 antagonists.

R. Campbell, D. Fry, L. Chen, 2002, Bioorganic & medicinal chemistry letters.

N-benzylpyroglutamyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.

J. Tilley, R. Trilles, R. Guthrie, 2000, Bioorganic & medicinal chemistry letters.

Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity.

L. Cowen, D. Krysan, G. Privé, 2021, Journal of medicinal chemistry.

Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.

S. Vajda, D. Beglov, M. Georgiadis, 2019, Journal of medicinal chemistry.

High-throughput Screening in Larval Zebrafish Identifies Novel Potent Sedative-hypnotics

S. Schaus, Wenqing Xu, Buwei Yu, 2018, Anesthesiology.

N-acyl-L-phenylalanine derivatives as potent VLA-4 antagonists that mimic a cyclic peptide conformation.

R. Campbell, D. Fry, L. Chen, 2002, Bioorganic & medicinal chemistry letters.

N-acyl phenylalanine analogues as potent small molecule VLA-4 antagonists.

K. Luk, J. Tilley, R. Trilles, 2000, Bioorganic & medicinal chemistry letters.

Asymmetric synthesis of a novel phenylogous amino acid mimicking an extended dipeptide

J. Tilley, R. Trilles, Lijing Chen, 1995 .

Synthesis of the Ezomycin Octosyl Nucleoside

Carlos Jaramillo, S. Nandan, R. Trilles, 1994 .

Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent Mechanism.

Daniel F Tardiff, S. Schaus, S. Lindquist, 2017, ACS chemical neuroscience.

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus

S. Lindquist, L. Cowen, D. Krysan, 2019, Nature Communications.

N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitors.

C. Steppan, J. Litchfield, R. Trilles, 2011, Bioorganic & medicinal chemistry letters.

New, Scalable Route for the Synthesis of a trans-Fused Hexahydro-1H-phenanthren-2-one from a Conjugated Tetrahydro-3H-phenanthren-2-one

G. Woodworth, R. Trilles, B. Morgan, 2003 .

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus

S. Lindquist, L. Cowen, D. Krysan, 2019, Nature Communications.

Synthesis of Neocannabinoids Using Controlled Friedel-Crafts Reactions.

Aaron B. Beeler, J. Porco, R. Trilles, 2023, The Journal of organic chemistry.