Chang-Ying Chu

发表

Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor lead identification.

Santhosh Kumar Chittimalla, Yi-Hui Peng, H. Hsieh, 2010, Journal of medicinal chemistry.

A high-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors.

H. Hsieh, T. Lien, Y. Chao, 2012, Anticancer research.

Catalytic enantioselective coupling of 2-naphthols by new chiral oxovanadium complexes bearing a self accelerating functional group

Chang-Ying Chu, B. Uang, 2003 .

Chiral oxovanadium complex catalyzed enantioselective oxidative coupling of 2-naphthols

Chang-Ying Chu, Der-Ren Hwang, B. Uang, 2001 .

Recent advances in the oxovanadium mediated biaryl coupling and modified Mannich-type reaction

Chang-Ying Chu, Der-Ren Hwang, P. Reddy, 2003 .

Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach.

H. Hsieh, C. Chen, Su-Ying Wu, 2009, Journal of medicinal chemistry.

Enantioselective silylcyanation of aldehydes catalyzed by new chiral oxovanadium complex

Chang-Ying Chu, B. Uang, Chu-Tin Hsu, 2011 .

Aerobic Oxidation of Hydroquinones to Quinones Catalyzed by VO(acac)2

Chang-Ying Chu, Der-Ren Hwang, B. Uang, 1999 .

Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.

Sing-Yi Wang, Mohane Selvaraj Coumar, Yu-Sheng Chao, 2010, Journal of medicinal chemistry.

Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine Aurora kinase inhibitor.

H. Hsieh, C. Chen, Y. Chao, 2013, Journal of medicinal chemistry.

Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules

Chi-Ying F. Huang, Yi-Hui Peng, H. Hsieh, 2013, Proceedings of the National Academy of Sciences.

Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer.

Yi-Hui Peng, H. Hsieh, C. Chen, 2019, Journal of medicinal chemistry.

Identification, SAR Studies, and X‐ray Co‐crystallographic Analysis of a Novel Furanopyrimidine Aurora Kinase A Inhibitor

H. Hsieh, Y. Chao, J. Hsu, 2010, ChemMedChem.

3D‐QSAR‐Assisted Drug Design: Identification of a Potent Quinazoline‐Based Aurora Kinase Inhibitor

Yung Chang Hsu, H. Hsieh, Y. Chao, 2013, ChemMedChem.

Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules

Chi-Ying F. Huang, Yi-Hui Peng, H. Hsieh, 2013, Proceedings of the National Academy of Sciences.