N. Ternette

发表

LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly

A. Snijders, J. Stoye, J. Attig, 2019, Genome research.

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding

Søren Buus, Nicola Ternette, Pietro Roversi, 2015, eLife.

Integral Use of Immunopeptidomics and Immunoinformatics for the Characterization of Antigen Presentation and Rational Identification of BoLA-DR–Presented Peptides and Epitopes

M. Nielsen, S. Buus, N. Ternette, 2021, The Journal of Immunology.

An open-source computational and data resource to analyze digital maps of immunopeptidomes

Alessandro Sette, Ruedi Aebersold, Lucia Espona, 2015, eLife.

NNAlign_MA; MHC Peptidome Deconvolution for Accurate MHC Binding Motif Characterization and Improved T-cell Epitope Predictions.

M. Nielsen, S. Buus, M. Andreatta, 2019, Molecular & cellular proteomics : MCP.

Mass spectrometry–based identification of MHC-bound peptides for immunopeptidomics

Sri H. Ramarathinam, Nicola Ternette, Anthony W Purcell, 2019, Nature Protocols.

Improved Prediction of Bovine Leucocyte Antigens (BoLA) Presented Ligands by Use of Mass-Spectrometry-Determined Ligand and in Vitro Binding Data

Morten Nielsen, Nicola Ternette, M. Nielsen, 2017, Journal of proteome research.

Immunopeptidomic Profiling of HLA‐A2‐Positive Triple Negative Breast Cancer Identifies Potential Immunotherapy Target Antigens

A. Hill, B. Kessler, N. Ternette, 2018, Proteomics.

Development of a T-cell Receptor Mimic Antibody against Wild-Type p53 for Cancer Immunotherapy.

B. Cornelissen, A. Banham, M. Cragg, 2017, Cancer research.

Discrimination Between Human Leukocyte Antigen Class I-Bound and Co-Purified HIV-Derived Peptides in Immunopeptidomics Workflows

P. Borrow, Anna E. Kliszczak, B. Kessler, 2018, Front. Immunol..

Identification of neoantigens in esophageal adenocarcinoma

B. Nicholas, P. Skipp, T. Elliott, 2022, bioRxiv.

Contribution of proteasome-catalyzed peptide cis-splicing to viral targeting by CD8+ T cells in HIV-1 infection

G. Learn, B. Haynes, I. Williams, 2019, Proceedings of the National Academy of Sciences.

Incoming HIV virion-derived Gag Spacer Peptide 2 (p1) is a target of effective CD8+ T cell antiviral responses.

C. Brander, V. Miller, T. Peto, 2021, Cell reports.

The viral vectored vaccine targeting Thymosin β10 controls tumour growth in a murine model of prostate cancer

Julius Mueller, A. Hill, I. Redchenko, 2021, bioRxiv.

Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers

Z. Szallasi, A. G. Pedersen, A. Eklund, 2020, Nature Communications.

HLA-DQÎ²57, anti-insulin T cells and insulin mimicry in autoimmune diabetes

M. Pekalski, R. Ferreira, M. Nakayama, 2022, medRxiv.

Improved prediction of Bovine Leucocyte Antigens (BoLA) presented ligands by use of MS eluted ligands and in-vitro binding data; impact for the identification T cell epitopes

M. Nielsen, N. Ternette, T. Connelley, 2017, bioRxiv.

Immunopeptidomics Special Issue

A. Purcell, N. Ternette, 2018, Proteomics.

Direct identification of HLA‐presented CD8 T cell epitopes from transmitted founder HIV‐1 variants

A. Purcell, E. Hunter, L. Yue, 2021, Proteomics.

Impact of Micropolymorphism Outside the Peptide Binding Groove in the Clinically Relevant Allele HLA-C*14 on T Cell Responses in HIV-1 Infection

P. Borrow, S. Oka, Wayne Paes, 2022, Journal of virology.

The Succinated Proteome of FH-Mutant Tumours

B. Teh, B. Kessler, Ming Yang, 2014, Metabolites.

Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes

F. Ashcroft, P. Rorsman, T. Soga, 2017, Cell reports.

Identification of an Unconventional Subpeptidome Bound to the Behçet's Disease-associated HLA-B*51:01 that is Regulated by Endoplasmic Reticulum Aminopeptidase 1 (ERAP1)*

Hui Shi, P. Bowness, Liye Chen, 2020, Molecular & Cellular Proteomics.

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

Sri H. Ramarathinam, Linden J. Gearing, J. Rossjohn, 2018, Science Immunology.

The Choice of HLA‐Associated Peptide Enrichment and Purification Strategy Affects Peptide Yields and Creates a Bias in Detected Sequence Repertoire

A. Purcell, N. Ternette, A. Nicastri, 2020, Proteomics.

Characterization of the Theileria parva sporozoite proteome International Journal for Parasitology

Joana C. Silva, V. Nene, K. Tretina, 2017 .

NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-Presentation and CD8 T Cell Responses

V. Cerundolo, A. Simmons, D. Muraro, 2019, Frontiers in immunology.

NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-presentation and CD8 T Cell Responses

V. Cerundolo, A. Simmons, D. Muraro, 2019, bioRxiv.

Protective Efficacy and Immunogenicity of an Adenoviral Vector Vaccine Encoding the Codon-Optimized F Protein of Respiratory Syncytial Virus

K. Überla, M. Tenbusch, V. Temchura, 2009, Journal of Virology.

Elucidation of the Signatures of Proteasome-Catalyzed Peptide Splicing

P. Borrow, Wayne Paes, N. Ternette, 2020, Frontiers in Immunology.

Elucidation of the signatures of proteasome-catalysed peptide splicing

P. Borrow, Wayne Paes, N. Ternette, 2020, bioRxiv.

Persistent but dysfunctional mucosal SARS-CoV-2-specific IgA and low lung IL-1β associate with COVID-19 fatal outcome: A cross-sectional analysis

L. Lopalco, D. Annane, J. Chiche, 2022, Frontiers in Immunology.

Expression of RNA virus proteins by RNA polymerase II dependent expression plasmids is hindered at multiple steps

K. Überla, S. Kuate, T. Grunwald, 2007, Virology Journal.

Detection of BK virus in urine from renal transplant subjects by mass spectrometry

B. Kessler, R. Konietzny, C. Pugh, 2012, Clinical Proteomics.

Know thy immune self and non‐self: Proteomics informs on the expanse of self and non‐self, and how and where they arise

N. Ternette, S. Joyce, 2021, Proteomics.

Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

P. Carmeliet, G. Stamp, H. Lockstone, 2011, Cancer cell.

1131 GRWD5769: A first-in-class inhibitor of ERAP1, generating novel cancer antigens to drive de novo anti-tumor T cell responses

A. Purcell, Wayne Paes, N. Ternette, 2022, Regular and Young Investigator Award Abstracts.

Label-free quantitative proteomics reveals regulation of interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) and 5'-3'-exoribonuclease 2 (XRN2) during respiratory syncytial virus infection

B. Kessler, N. Ternette, H. Kramer, 2011, Virology Journal.

Ionizing Radiation Drives Key Regulators of Antigen Presentation and a Global Expansion of the Immunopeptidome

Isaac B. Woodhouse, S. Salatino, R. Muschel, 2022, Molecular & cellular proteomics : MCP.

Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency

T. Soga, R. Fischer, Keiko Kato, 2013, Cell reports.

Defining the HLA class I‐associated viral antigen repertoire from HIV‐1‐infected human cells

M. Nielsen, C. Brander, P. Borrow, 2015, European journal of immunology.

Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates

Norman L. Letvin, Persephone Borrow, Nicola Ternette, 2016, Journal of Virology.

Aberrant succination of proteins in fumarate hydratase‐deficient mice and HLRCC patients is a robust biomarker of mutation status

L. Aaltonen, A. Harris, Jennifer M. Taylor, 2011, The Journal of pathology.

E3 Ligases Determine Ubiquitination Site and Conjugate Type by Enforcing Specificity on E2 Enzymes*

T. Ziv, B. Kessler, Yakir Dadon, 2011, The Journal of Biological Chemistry.

HLA variants have different preferences to present proteins with specific molecular functions which are complemented in frequent haplotypes

Isaac B. Woodhouse, P. Borrow, D. Chudakov, 2022, Frontiers in Immunology.

The interdependence of machine learning and LC-MS approaches for an unbiased understanding of the cellular immunopeptidome

M. Nielsen, C. Barra, N. Ternette, 2022, Expert review of proteomics.

HLA binding of self-peptides is biased towards proteins with specific molecular functions

Isaac B. Woodhouse, P. Borrow, D. Chudakov, 2021, bioRxiv.

Integral Use of Immunopeptidomics and Immunoinformatics for the Characterization of Antigen Presentation and Rational Identification of BoLA-DR–Presented Peptides and Epitopes

M. Nielsen, S. Buus, N. Ternette, 2020, The Journal of Immunology.

Long non-coding RNA-derived peptides are immunogenic and drive a potent anti-tumour response

P. Klenerman, Alexander Kanapin, Geng-Hung Liu, 2023, Nature Communications.

The Choice of Search Engine Affects Sequencing Depth and HLA Class I Allele-Specific Peptide Repertoires

K. Schnatbaum, U. Reimer, H. Wenschuh, 2021, Molecular & cellular proteomics : MCP.

MS‐Rescue: A Computational Pipeline to Increase the Quality and Yield of Immunopeptidomics Experiments

Morten Nielsen, Massimo Andreatta, Annalisa Nicastri, 2019, Proteomics.

NNAlign_MA; MHC Peptidome Deconvolution for Accurate MHC Binding Motif Characterization and Improved T-cell Epitope Predictions

Massimo Andreatta, Søren Buus, Nicola Ternette, 2019, Molecular & Cellular Proteomics.

The SysteMHC Atlas project

Roman A. Zubarev, Emanuel Schmid, Witold Wolski, 2017, Nucleic Acids Res..

Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells

Elisa Pappalardo, Lucy Dorrell, Nicola Ternette, 2015, Journal of Virology.

Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells

B. Haynes, P. Borrow, P. Acharya, 2021, Cell Reports.

Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells

B. Haynes, P. Borrow, P. Acharya, 2020, bioRxiv.

Comparative evaluation of label‐free SINQ normalized spectral index quantitation in the central proteomics facilities pipeline

Benjamin Thomas, Nicola Ternette, Oreste Acuto, 2011, Proteomics.

Immunogenicity and efficacy of codon optimized DNA vaccines encoding the F-protein of respiratory syncytial virus.

K. Uberla, T. Grunwald, N. Ternette, 2007, Vaccine.

Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation

Konrad U. Förstner, Daniel J. Wilson, Christian W. Remmele, 2016, Proceedings of the National Academy of Sciences.

Immunopeptidomic Analysis of BoLA-I and BoLA-DR Presented Peptides from Theileria parva Infected Cells

M. Nielsen, S. Buus, C. Vrettou, 2022, Vaccines.

Identification of Immunodominant HIV-1 Epitopes Presented by HLA-C*12:02, a Protective Allele, Using an Immunopeptidomics Approach

P. Borrow, S. Oka, Wayne Paes, 2019, Journal of Virology.

J. Satsangi, N. Ternette, R. Powell Doherty, 2021, Gastroenterology.

Extended Analysis Identifies Drug-Specific Association of Two Distinct HLA Class II Haplotypes for Development of Immunogenicity to Adalimumab and Infliximab.

J. Satsangi, N. Ternette, R. Powell Doherty, 2020, Gastroenterology.

Identification of neoantigens in oesophageal adenocarcinoma

B. Nicholas, P. Skipp, R. Parker, 2023 .

Characterization of the Theileria parva sporozoite proteome

Nicola Ternette, Vishvanath Nene, Joana C. Silva, 2017, International journal for parasitology.

In-depth mining of the immunopeptidome of an acute myeloid leukemia cell line using complementary ligand enrichment and data acquisition strategies.

Sri H. Ramarathinam, N. Mifsud, A. Purcell, 2020, Molecular immunology.

Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA–B27

N. Shastri, T. Elliott, R. Fischer, 2014, Arthritis & rheumatology.

Large-Scale Immuno-Peptidome Analysis Reveals Recurrent Post-Translational Splicing of Cancer and Immune-Associated Genes.

Ronen Levy, Y. Samuels, Merav D Shmueli, 2023, Molecular & cellular proteomics : MCP.

Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine

M. Vogel, D. Speiser, S. Salatino, 2019, Front. Immunol..

NNAlign_MA; semi-supervised MHC peptidome deconvolution for accurate characterization of MHC binding motifs and improved T cell epitope prediction

Massimo Andreatta, Morten Nielsen, Bruno Alvarez, 2019 .

Identification of Native and Posttranslationally Modified HLA‐B*57:01‐Restricted HIV Envelope Derived Epitopes Using Immunoproteomics

Sri H. Ramarathinam, S. Alcântara, R. Center, 2018, Proteomics.

Decitabine increases neoantigen and cancer testis antigen expression to enhance T-cell–mediated toxicity against glioblastoma

Isaac B. Woodhouse, G. Ogg, V. Cerundolo, 2022, Neuro-oncology.

The Choice of HLA-Associated Peptide Enrichment and Purification Strategy Affects Peptide Yields and Creates a Bias in Detected Sequence Repertoire.

A. Purcell, N. Ternette, A. Nicastri, 2020, Proteomics.

NetMHCphosPan - Pan-specific prediction of MHC class I antigen presentation of phosphorylated ligands

M. Nielsen, C. Barra, N. Ternette, 2021, ImmunoInformatics.

Minimal Information About an Immuno‐Peptidomics Experiment (MIAIPE)

Juan Antonio Vizcaíno, Bjoern Peters, Alessandro Sette, 2018, Proteomics.

Novel canonical and non-canonical viral antigens extend current targets for immunotherapy of HPV-driven cervical cancer

Isaac B. Woodhouse, S. Salatino, R. Parker, 2023, iScience.

The Human Otubain2-Ubiquitin Structure Provides Insights into the Cleavage Specificity of Poly-Ubiquitin-Linkages

D. Stuart, T. Walter, B. Kessler, 2015, PloS one.

Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress

G. Dianov, J. Parsons, I. Dianova, 2012, Nucleic acids research.

A quantitative label-free analysis of the extracellular proteome of human supraspinatus tendon reveals damage to the pericellular and elastic fibre niches in torn and aged tissue

A. Carr, B. Kessler, N. Ternette, 2017, PloS one.

Renal cyst formation in Fh 1-deficient mice is independent of the Hif / Phd pathway

P. Carmeliet, G. Stamp, H. Lockstone, 2011 .

Identification of antigens presented by MHC for vaccines against tuberculosis

P. Bettencourt, S. Waddell, H. McShane, 2020, npj Vaccines.

Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability

G. Dianov, J. Parsons, I. Dianova, 2011, Nucleic acids research.

ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage

G. Dianov, J. Parsons, I. Dianova, 2012, Molecular cell.

How mass spectrometric interrogation of MHC class I ligandomes has advanced our understanding of immune responses to viruses.

A. Purcell, N. Ternette, Eleni Adamopoulou, 2023, Seminars in immunology.

Selective Binding of AIRAPL Tandem UIMs to Lys48-Linked Tri-Ubiquitin Chains.

T. Matsui, T. Weiss, I. Braunstein, 2016, Structure.

Tyrosine dephosphorylation is required for Bak activation in apoptosis

I. Leigh, A. Storey, B. Kessler, 2010, The EMBO journal.

Detection of BK virus in urine from renal transplant subjects by mass spectrometry

R. Fischer, B. Kessler, R. Konietzny, 2012, Clinical Proteomics.

Mass spectrometry–based identification of MHC-bound peptides for immunopeptidomics

Sri H. Ramarathinam, A. Purcell, N. Ternette, 2019, Nature Protocols.

NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-Presentation and CD8 T Cell Responses

V. Cerundolo, A. Simmons, D. Muraro, 2019, bioRxiv.

Minor differences in peptide presentation between chicken MHC class I molecules can explain differences in disease susceptibility

J. Kaufman, William J. Liu, Y. Chai, 2022, bioRxiv.

Interferon-α promotes neo-antigen formation and preferential HLA-B-restricted antigen presentation in pancreatic β-cells

P. Marchetti, D. Eizirik, M. Colli, 2023, bioRxiv.

Incoming HIV Virion-Derived Gag Spacer Peptide 2 (p1) is a Target of Effective CD8+ T Cell Antiviral Responses

C. Brander, V. Miller, T. Peto, 2020, SSRN Electronic Journal.

Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response.

Bridget E. Begg, L. Eisenlohr, K. Lynch, 2023, Nature immunology.

MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer

Isaac B. Woodhouse, P. Borrow, L. Eisenlohr, 2024, Nature communications.

Reply to GASTRO-D-20-01158: The PANTS study highlights the importance of considering HLA linkage disequilibrium in genome-wide association studies for accurate calculation of statistical power and meaningful biological interpretation.

J. Satsangi, N. Ternette, Hanqing Liao, 2020, Gastroenterology.