D. Misner

发表

Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.

D. Sampath, P. Dragovich, T. O'Brien, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

Investigation of mechanism of drug‐induced cardiac injury and torsades de pointes in cynomolgus monkeys

K. Kolaja, L. Guo, M. Albassam, 2012, British journal of pharmacology.

Therapeutic Antibody-Induced Vascular Toxicity Due to Off-Target Activation of Nitric Oxide in Cynomolgus Monkeys.

Anu V. Connor, Hong Wang, D. Danilenko, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

BTK small molecule inhibitors induce a distinct pancreatic toxicity in rats

Adam R. Johnson, Li-chuan, M. Hedehus, 2016 .

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer

D. Danilenko, J. DeVoss, A. Zarrin, 2019, Front. Immunol..

Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)

J. Deval, J. Symons, D. Misner, 2020, bioRxiv.

Title page

F. Knoflach, G. Tombaugh, D. Misner, 2021, Gigantism and Acromegaly.

In vitro assessment of chemotherapy-induced neuronal toxicity.

D. Sheinson, D. Misner, T. Ngo, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Cardiotoxicity Associated with Nicotinamide Phosphoribosyltransferase Inhibitors in Rodents and in Rat and Human-Derived Cells Lines

A. Bruening-Wright, D. Sampath, P. Dragovich, 2017, Cardiovascular Toxicology.

Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats

Adam R. Johnson, M. Hedehus, R. Carano, 2017, The Journal of Pharmacology and Experimental Therapeutics.

ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model

A. Marchand, C. Liu, J. Neyts, 2021, bioRxiv.

Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity

C. Stevens, R. Evans, Charles F. Stevens, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development.

Adam R. Johnson, BinQing Wei, C. Eigenbrot, 2018, Journal of medicinal chemistry.

Mechanism of Cannabinoid Effects on Long-Term Potentiation and Depression in Hippocampal CA1 Neurons

J. Sullivan, D. Misner, 1999, The Journal of Neuroscience.

An Essential Role for Retinoid Receptors RARβ and RXRγ In Long-Term Potentiation and Depression

F. Gage, T. Schikorski, C. Stevens, 1998, Neuron.

Stereochemical Differences in Fluorocyclopropyl Amides Enable Tuning of Btk Inhibition and Off-Target Activity.

Adam R. Johnson, C. Eigenbrot, J. Lubach, 2020, ACS medicinal chemistry letters.

3,4-Dihydro-2H-benzo[1,4]oxazine derivatives as 5-HT6 receptor antagonists.

D. Misner, J. Berger, D. Schwab, 2007, Bioorganic & medicinal chemistry letters.

9. Utilization of In Vitro Neurotoxicity Models in Pre-Clinical Toxicity Assessment

D. Dambach, D. Misner, K. Staflin, 2016 .

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer.

Deepak Sampath, Tanja S. Zabka, D. Sampath, 2015, Pharmacology & therapeutics.

An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression.

F. Gage, T. Schikorski, C. Stevens, 1998, Neuron.

Assessing hERG channel inhibition using PatchXpress.

D. Misner, Dinah L Misner, Justin Q Ly, 2007, Clinics in laboratory medicine.

Title Page

D. Bertrand, M. Milla, F. Knoflach, 2018, Public Health Genomics.

Characterization of RO5126946, a Novel α7 Nicotinic Acetylcholine Receptor–Positive Allosteric Modulator

D. Bertrand, M. Milla, F. Knoflach, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Characterization of RO 5126946 , a Novel a 7 Nicotinic Acetylcholine Receptor – Positive Allosteric Modulator s

D. Bertrand, M. Milla, F. Knoflach, 2014 .

Neuregulin1 (NRG1) Signaling through Fyn Modulates NMDA Receptor Phosphorylation: Differential Synaptic Function in NRG1+/− Knock-Outs Compared with Wild-Type Mice

Kari Stefansson, Hreinn Stefansson, Thorkell Andresson, 2007, The Journal of Neuroscience.

Contactin Supports Synaptic Plasticity Associated with Hippocampal Long-Term Depression but Not Potentiation

K. Murai, D. Misner, B. Ranscht, 2002, Current Biology.

For a series of methylindole analogs, reactive metabolite formation is a poor predictor of intrinsic cytotoxicity in human hepatocytes

C. Hop, D. Misner, J. Halladay, 2014 .

Enhanced long-term depression and impaired reversal learning in phosphodiesterase 4B-knockout (PDE4B −/−) mice

A. Blokland, J. Prickaerts, Melissa G. Works, 2011, Neuropharmacology.

Abstract 4520: Preclinical characterization of ALG-031048, a novel STING agonist with potent anti-tumor activity in mice

Qingling Zhang, J. Deval, J. Symons, 2020 .

Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid

Dolores Diaz, Deepak Sampath, Hirdesh Uppal, 2015, Toxicology mechanisms and methods.

Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310.

D. Sutherlin, Jun Chen, D. Hackos, 2021, Journal of medicinal chemistry.

Enhanced long‐term potentiation and impaired learning in phosphodiesterase 4D‐knockout (PDE4D−/−) mice

A. Blokland, Melissa G. Works, L. Santarelli, 2008, The European journal of neuroscience.

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer.

D. Sampath, P. Dragovich, T. O'Brien, 2015, Pharmacology & therapeutics.

ALG-000184, a prodrug of capsid assembly modulator ALG-001075, demonstrates best-in-class preclinical characteristics for the treatment of chronic hepatitis B

R. Schinazi, Qingling Zhang, J. Deval, 2020, Journal of Hepatology.