Yang Xiao

发表

Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).

Karl H. Clodfelter, P. Bauer, N. Kley, 2013, Bioorganic & medicinal chemistry letters.

Suppression of Cellular Proliferation and Invasion by HMGB1 Knockdown in Bladder Urothelial Carcinoma Cells

Yang Xiao, Haiqiu Liao, Yingbin Hu, 2015, Oncology research.

Blocking PD-1/PD-L1 by an ADCC enhanced anti-B7-H3/PD-1 fusion protein engages immune activation and cytotoxicity.

Yang Yang, Yang Xiao, Liwen Zhao, 2020, International immunopharmacology.

B7-H3 expression in breast cancer and upregulation of VEGF through gene silence

Yun-di Guo, Guang Bai, Xiaoning Li, 2014, OncoTargets and therapy.

A human t-PA mutant cDNA cassette knocked in the murine fgfr-4 locus targeting for mammary gland expression.

Xuan Cheng, Yang Xiao, Jixian Deng, 2004, Acta biochimica et biophysica Sinica.

14-3-3σ is an independent prognostic biomarker for gastric cancer and is associated with apoptosis and proliferation in gastric cancer

Chao Zeng, Yang Xiao, T. Zeng, 2014, Oncology letters.

The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth via triggering autophagy

Bing Li, Jianjun Gao, Yang Xiao, 2018, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).

Brandon J. Bravo, Qiang Zhao, N. Skelton, 2013, Journal of medicinal chemistry.

Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models.

Leslie B. Lee, D. Sampath, P. Jackson, 2013, Neoplasia.

IdentificationofPreferredChemotherapeuticsforCombining with a CHK1 Inhibitor

Marie Evangelista, S. Malek, P. Jackson, 2013 .

Inhibitory effect of epigallocatechin-3-gallate on bladder cancer cells via autophagy pathway

Chen, Yonggang, Yang Xiao, 2016 .

Establishment and application of recombinant hepatitis delta antigen

Yang Xiao, 2004 .

Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma.

Karl A. Merrick, T. O'Brien, A. Jakalian, 2019, Bioorganic & medicinal chemistry letters.

Identification of Preferred Chemotherapeutics for Combining with a CHK1 Inhibitor

Thomas V. O'brien, S. Malek, P. Jackson, 2013, Molecular Cancer Therapeutics.

Small Molecule Therapeutics Identi fi cationof PreferredChemotherapeutics forCombining with a CHK 1 Inhibitor

S. Malek, P. Jackson, Katarzyna Kowanetz, 2013 .

ACTL6A promotes repair of cisplatin-induced DNA damage, a new mechanism of platinum resistance in cancer

F. Lin, Yang Xiao, Weei-Chin Lin, 2021, Proceedings of the National Academy of Sciences.

Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618.

Leslie B. Lee, D. Sampath, P. Jackson, 2013, Neoplasia.

Combination Drug Scheduling Defines a “Window of Opportunity” for Chemopotentiation of Gemcitabine by an Orally Bioavailable, Selective ChK1 Inhibitor, GNE-900

Ivana Yen, S. Malek, T. O'Brien, 2013, Molecular Cancer Therapeutics.

Small Molecule Therapeutics Combination Drug Scheduling De fi nes a " Window of Opportunity " for Chemopotentiation of Gemcitabine by an Orally Bioavailable , Selective ChK 1 Inhibitor , GNE-900

Ivana Yen, S. Malek, T. O'Brien, 2013 .

Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable

M. Belvin, A. Daemen, G. Hatzivassiliou, 2016, PloS one.

Long noncoding RNA XIST is a prognostic factor in colorectal cancer and inhibits 5-fluorouracil-induced cell cytotoxicity through promoting thymidylate synthase expression

Yang Xiao, Usenko Alexander Yurievich, Smorzhevskyi Valentyn Yosypovych, 2017, Oncotarget.

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death.

A. Isacchi, E. Casale, Daniel J. Anderson, 2013, Nature chemical biology.

Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death

J. Zha, L. Rangell, P. Jackson, 2013, Cell cycle.

Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.

S. Duan, Y. Rao, J. Geng, 2003, Cancer cell.

Loss of NAPRT1 Expression by Tumor-Specific Promoter Methylation Provides a Novel Predictive Biomarker for NAMPT Inhibitors

R. Bourgon, K. Walter, T. Pham, 2013, Clinical Cancer Research.

CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer

Shixia Huang, Yang Xiao, Joshua D Graves, 2019, Breast Cancer Research.

A DNA aptamer reveals an allosteric site for inhibition in metallo-β-lactamases

Benjamin J. Wylie, R B Sutton, Yang Xiao, 2019, PloS one.

Discovery of a novel anti PD-L1 X TIGIT bispecific antibody for the treatment of solid tumors.

Yang Xiao, Liqiong Liu, Liwen Zhao, 2021, Cancer treatment and research communications.

14-3-3τ Promotes Breast Cancer Invasion and Metastasis by Inhibiting RhoGDIα

F. Lin, S. Ke, Yang Xiao, 2014, Molecular and Cellular Biology.

Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties.

Yang Xiao, Lei Zhang, Karl H. Clodfelter, 2013, Bioorganic & medicinal chemistry letters.

Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors.

N. Skelton, D. Sampath, K. Bair, 2016, Journal of medicinal chemistry.

Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility.

Karl H. Clodfelter, N. Skelton, D. Sampath, 2015, Bioorganic & medicinal chemistry letters.

Programmed cell death factor 4 enhances the chemosensitivity of colorectal cancer cells to Taxol.

Yang Xiao, Q. Hou, Daqing Wang, 2019, Oncology letters.

Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).

Yang Xiao, Lei Zhang, Deepak Sampath, 2013, Bioorganic & medicinal chemistry letters.

Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors.

Karl H. Clodfelter, P. Bauer, N. Kley, 2013, Journal of medicinal chemistry.

Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors

D. Sampath, K. Bair, Weiru Wang, 2014, PloS one.

Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).

Brandon J. Bravo, Qiang Zhao, N. Skelton, 2014, Bioorganic & medicinal chemistry letters.

Reduced NK Cell Cytotoxicity by Papillomatosis-Derived TGF-β Contributing to Low-Risk HPV Persistence in JORRP Patients

D. Guo, Yang Xiao, M. Liu, 2022, Frontiers in Immunology.

Development of a RT-PCR for the Detection of European Brown Hare Syndrome Virus

Zengqi Yang, Yang Xiao, Y. Zhang, 2011 .

Preliminary Function Analysis of Rice OsRab7 in Salt Tolerance and Construction of Its Genetic Transformation Vector

Yang Xiao, 2008 .

Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).

Brandon J. Bravo, Qiang Zhao, N. Skelton, 2013, Journal of medicinal chemistry.

Identification of Preferred Chemotherapeutics for Combining with a CHK1 Inhibitor

S. Malek, P. Jackson, Katarzyna Kowanetz, 2013, Molecular Cancer Therapeutics.

Abnormal Activation of Myeloid Dendritic Cells in JORRP Patients and Associated with Disease Activity.

Yang Xiao, Jun Wang, Lijing Ma, 2019, Immunology letters.