Philip E. Chen

发表

Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene

R. Ribchester, M. Shipston, T. Gillingwater, 2007, Molecular Neurodegeneration.

A new strategy to increase RNA editing at the Q/R site of GluA2 AMPA receptor subunits by targeting alternative splicing patterns of ADAR2

L. Popplewell, G. Dickson, Philip E. Chen, 2021, Journal of Neuroscience Methods.

Seizure control by decanoic acid through direct AMPA receptor inhibition

M. Walker, J. Hardege, Philip E. Chen, 2015, Brain : a journal of neurology.

Seizure control by ketogenic diet-associated medium chain fatty acids

M. Walker, N. Plant, Philip E. Chen, 2013, Neuropharmacology.

The neuroprotective Wld S gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells

R. Ribchester, T. Gillingwater, J. Haley, 2006 .

Absence of Whisker-Related Pattern Formation in Mice with NMDA Receptors Lacking Coincidence Detection Properties and Calcium Signaling

S. Hunt, I. Dean, A. Gibb, 2003, The Journal of Neuroscience.

Glutamate receptor gating.

S. Traynelis, K. Erreger, D. Wyllie, 2004, Critical reviews in neurobiology.

Subunit-Specific Agonist Activity at NR2A-, NR2B-, NR2C-, and NR2D-Containing N-Methyl-d-aspartate Glutamate Receptors

Matthew T. Geballe, J. Snyder, S. Traynelis, 2007, Molecular Pharmacology.

Subunit-Specific Agonist Activity at NR 2 A-, NR 2 B-, NR 2 C-, and NR 2 D-Containing N-Methyl-D-aspartate Glutamate Receptors

Matthew T. Geballe, J. Snyder, S. Traynelis, 2007 .

Development of an antisense oligonucleotide based method to manipulate RNA editing of AMPAR subunits

L. Popplewell, G. Dickson, Philip E. Chen, 2014 .

Pharmacological insights obtained from structure–function studies of ionotropic glutamate receptors

D. Wyllie, Philip E. Chen, P. Chen, 2006, British journal of pharmacology.

Identification of Amino Acid Residues of the NR2A Subunit That Control Glutamate Potency in Recombinant NR1/NR2A NMDA Receptors

D. Colquhoun, D. Wyllie, Philip E. Chen, 1998, The Journal of Neuroscience.

Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

D. Wyllie, Philip E. Chen, E. Baker, 2008, The Journal of physiology.

Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

Matthew T. Geballe, J. Snyder, S. Traynelis, 2008, The Journal of physiology.

Equilibrium Constants for (R)-[(S)-1-(4-Bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic Acid (NVP-AAM077) Acting at Recombinant NR1/NR2A and NR1/NR2B N-Methyl-d-aspartate Receptors: Implications for Studies of Synaptic Transmission

D. Wyllie, Philip E. Chen, P. Frizelle, 2006, Molecular Pharmacology.

Single‐channel analysis of a point mutation of a conserved serine residue in the S2 ligand‐binding domain of the NR2A NMDA receptor subunit

A. Johnston, D. Lipscombe, D. Wyllie, 2006, The Journal of physiology.

Structural Features of the Glutamate Binding Site in Recombinant NR1/NR2A N-Methyl-d-aspartate Receptors Determined by Site-Directed Mutagenesis and Molecular Modeling

Matthew T. Geballe, J. Snyder, A. Johnston, 2005, Molecular Pharmacology.

Influence of a threonine residue in the S2 ligand binding domain in determining agonist potency and deactivation rate of recombinant NR1a/NR2D NMDA receptors

A. Johnston, D. Wyllie, Philip E. Chen, 2004, The Journal of physiology.

Edinburgh Research Explorer Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors

D. Colquhoun, D. Wyllie, Philip E. Chen, 2022 .

Behavioral deficits and subregion-specific suppression of LTP in mice expressing a population of mutant NMDA receptors throughout the hippocampus.

T. Bliss, R. Morris, C. Specht, 2009, Learning & memory.

Spatial learning is unimpaired in mice containing a deletion of the alpha‐synuclein locus

R. Morris, C. Specht, Philip E. Chen, 2002, The European journal of neuroscience.

Perampanel and decanoic acid show synergistic action against AMPA receptors and seizures

M. Walker, M. Cunningham, Alistair J. Jenkins, 2018, Epilepsia.

The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells.

Kevin A. Robertson, R. Ribchester, J. Haley, 2006, Human molecular genetics.