T. Olson

发表

Mutations in ribonucleic acid binding protein gene cause familial dilated cardiomyopathy.

P. Pellikka, M. de Andrade, R. Rodeheffer, 2009, Journal of the American College of Cardiology.

Familial atrial fibrillation is a genetically heterogeneous disorder.

Douglas L Packer, Dawood Darbar, Timothy M Olson, 2003, Journal of the American College of Cardiology.

Inherited Arrhythmias: A National Heart, Lung, and Blood Institute and Office of Rare Diseases Workshop Consensus Report About the Diagnosis, Phenotyping, Molecular Mechanisms, and Therapeutic Approaches for Primary Cardiomyopathies of Gene Mutations Affecting Ion Channel Function

Michael J Ackerman, Colleen E Clancy, Stephan E Lehnart, 2007, Circulation.

Patient-specific functional genomics and disease modeling suggest a role for LRP2 in Hypoplastic Left Heart Syndrome

Timothy J. Nelson, K. Ocorr, R. Bodmer, 2019, bioRxiv.

Hypoplastic Left Heart Syndrome: An Overview for Primary Care Providers

F. Cetta, P. O’Leary, Sameh M. Said, 2019, Pediatrics in Review.

1 Title : Post-hoc Analysis for Detecting Individual Rare Variant Risk Associations using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies Running Title : Bayesian Probit Rare Variant Analysis

A. Whittemore, D. Schaid, J. Carpten, 2017 .

KATP channel polymorphism is associated with left ventricular size in hypertensive individuals: a large-scale community-based study

A. Terzic, R. Rodeheffer, S. Reyes, 2008, Human Genetics.

Cardiac KATP channels in health and disease.

A. Terzic, S. Yamada, T. Olson, 2005, Journal of molecular and cellular cardiology.

KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation

A. Terzic, A. Jahangir, S. Seino, 2007, Nature Clinical Practice Cardiovascular Medicine.

Progression of familial and non-familial dilated cardiomyopathy: long term follow up

D. Schaid, E. Atkinson, D. Driscoll, 2003, Heart.

Recessive TAF1A mutations reveal ribosomopathy in siblings with end-stage pediatric dilated cardiomyopathy

Jared Evans, J. Maleszewski, T. Olson, 2017, Human molecular genetics.

Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs

Angela R. Miller, Timothy J. Nelson, L. Steinmetz, 2020, Nature Medicine.

LRRC10 is required to maintain cardiac function in response to pressure overload.

T. Kamp, Youngsook Lee, T. Hacker, 2016, American journal of physiology. Heart and circulatory physiology.

Uncovering an intermediate phenotype associated with rs2200733 at 4q25 in lone atrial fibrillation.

K. J. Herron, T. Olson, Kathleen J. Herron, 2011, The American journal of cardiology.

A Functional Genetic Variant (N521D) in Natriuretic Peptide Receptor 3 Is Associated with Diastolic Dysfunction: The Prevalence of Asymptomatic Ventricular Dysfunction Study

K. Bailey, R. Rodeheffer, M. Redfield, 2014, PloS one.

The effect of the brain-type natriuretic peptide single-nucleotide polymorphism rs198389 on test characteristics of common assays.

R. Rodeheffer, M. Redfield, D. Mahoney, 2011, Mayo Clinic proceedings.

TNNI 3 K mutation in familial syndrome of conduction system disease , atrial tachyarrhythmia and dilated cardiomyopathy

Michael T. Zimmermann, E. Wieben, M. Zimmermann, 2014 .

Familial spontaneous coronary artery dissection: evidence for genetic susceptibility.

K. Goel, S. Hayes, J. Maleszewski, 2015, JAMA internal medicine.

B-type natriuretic peptide single nucleotide polymorphism rs198389 and survival in the general community

R. Rodeheffer, M. Redfield, D. Mahoney, 2009 .

B-type natriuretic peptide single nucleotide polymorphism rs198389 is highly prevalent and impacts test characteristics of common assays

R. Rodeheffer, M. Redfield, D. Mahoney, 2009, BMC Pharmacology.

B-type natriuretic peptide single nucleotide polymorphism rs198389 and survival in the general community

R. Rodeheffer, M. Redfield, D. Mahoney, 2009, BMC Pharmacology.

Defining the molecular genetic basis of idiopathic dilated cardiomyopathy.

M. Keating, T. Olson, Mark T. Keating, 1997, Trends in cardiovascular medicine.

A human atrial natriuretic peptide gene mutation reveals a novel peptide with enhanced blood pressure-lowering, renal-enhancing, and aldosterone-suppressing actions.

J. Burnett, A. Cataliotti, T. Olson, 2009, Journal of the American College of Cardiology.

Comprehensive mutation scanning of LMNA in 268 patients with lone atrial fibrillation.

Katharine M Brauch, T. Olson, Lin Y. Chen, 2009, The American journal of cardiology.

Spontaneous coronary artery dissection and its association with heritable connective tissue disorders

S. Kirmani, S. Hayes, D. Deyle, 2016, Heart.

Metavinculin Mutations Alter Actin Interaction in Dilated Cardiomyopathy

M. Keating, S. Illenberger, B. Jockusch, 2002, Circulation.

Natriuretic peptides and myocardial structure: insights from population genetics.

J. Burnett, T. Olson, 2007, Hypertension.

Cell-Based Therapy for Myocardial Dysfunction After Fontan Operation in Hypoplastic Left Heart Syndrome

A. Dietz, D. Hagler, J. Dearani, 2017, Mayo Clinic proceedings. Innovations, quality & outcomes.

Genetic Association between Hypoplastic Left Heart Syndrome and Cardiomyopathies.

W. Bamlet, Jared Evans, P. O’Leary, 2020, Circulation. Genomic and precision medicine.

What makes the heart fail? New insights from defective genes

T. Olson, 2006 .

What makes the heart fail? New insights from defective genes.

T. Olson, 2006, Acta paediatrica (Oslo, Norway : 1992). Supplement.

Monogenic dilated cardiomyopathy

T. Olson, 2005 .

Actin mutations in dilated cardiomyopathy, a heritable form of heart failure.

S. Thibodeau, M. Keating, Y. Tai, 1998, Science.

Myosin Light Chain Mutation Causes Autosomal Recessive Cardiomyopathy With Mid-Cavitary Hypertrophy and Restrictive Physiology Brief Rapid Communication

D. Driscoll, F. Whitby, Margaret L. Karst, 2002 .

Investigating genetic variation of adrenergic receptors in familial stress cardiomyopathy (apical ballooning syndrome).

A. Prasad, T. Olson, Adele D Handy, 2009, Journal of cardiology.

Transcriptional atlas of cardiogenesis maps congenital heart disease interactome.

J. Kocher, A. Terzic, T. Nelson, 2014, Physiological genomics.

A breakthrough in spontaneous coronary artery dissection pathogenesis: is it an inherited condition?

S. Hayes, T. Olson, R. Gulati, 2017, Expert review of cardiovascular therapy.

Symptoms Chest pain Chest and left axillary pain Chest pain Not known Chest pain Chest and jaw pain Cardiac arrest Chest pain Chest pain Midsternal chest pain

K. Goel, S. Hayes, J. Maleszewski, 2015 .

Pulmonary microthrombi. Caveat for successful modified Fontan operation.

W. Edwards, D. Driscoll, F. J. Puga, 1993, Journal of Thoracic and Cardiovascular Surgery.

Amendment history : Corrigendum ( April 2017 ) A modifier screen identifies DNAJB 6 as a cardiomyopathy susceptibility gene

S. Ekker, Xueying Lin, Yongyong Shi, 2018 .

A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene.

S. Ekker, Xueying Lin, Yongyong Shi, 2016, JCI insight.

Autosomal dominant supravalvular aortic stenosis: localization to chromosome 7.

J. Weber, D. Schaid, S. Thibodeau, 1993, Human molecular genetics.

Compound heterozygous NOTCH1 mutations underlie impaired cardiogenesis in a patient with hypoplastic left heart syndrome

M. de Andrade, Jared Evans, T. Nelson, 2015, Human Genetics.

Ebstein anomaly, left ventricular non‐compaction, and early onset heart failure associated with a de novo α‐tropomyosin gene mutation

T. Olson, A. Cabalka, Angela M. Kelle, 2016, American journal of medical genetics. Part A.

From Safety to Benefit in Cell Delivery During Surgical Repair of Ebstein Anomaly: Initial Results.

J. Dearani, T. Nelson, B. Cannon, 2021, The Annals of thoracic surgery.

Regenerative therapy for hypoplastic left heart syndrome: first report of intraoperative intramyocardial injection of autologous umbilical-cord blood-derived cells.

H. Burkhart, T. Nelson, F. Cetta, 2015, The Journal of thoracic and cardiovascular surgery.

Abstract 3272: B-Type Natriuretic Peptide Single Nucleotide Polymorphism rs198389 Impacts Test Characteristics of Common Assays

R. Rodeheffer, M. Redfield, D. Mahoney, 2009 .

Idiopathic Restrictive Cardiomyopathy in Children and Young Adults.

M. Ackerman, D. Driscoll, F. Cetta, 2018, The American journal of cardiology.

Atrial natriuretic peptide frameshift mutation in familial atrial fibrillation.

M. de Andrade, L. Zingman, D. Darbar, 2008, The New England journal of medicine.

Rare Missense Variants in TLN1 Are Associated With Familial and Sporadic Spontaneous Coronary Artery Dissection

Jared Evans, S. Hayes, M. O'byrne, 2019, Circulation. Genomic and precision medicine.

Time course transcriptome data analysis for in vitro modeling of dilated cardiomyopathy using patient-derived induced pluripotent stem cells

J. Kocher, A. Terzic, T. Nelson, 2015, BMC Bioinformatics.

ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating

Yuan-Ping Pang, Martin Bienengraeber, Andre Terzic, 2004, Nature Genetics.

Model System Identification of Novel Congenital Heart Disease Gene Candidates: focus on RPL13.

Michael S. Yu, Timothy J. Nelson, J. Rosenfeld, 2019, Human molecular genetics.

Human KATP channelopathies: diseases of metabolic homeostasis

A. Terzic, T. Olson, 2009, Pflügers Archiv - European Journal of Physiology.

Cardiac Transcriptome and Dilated Cardiomyopathy Genes in Zebrafish

Christian A. Ross, Hu Li, T. Olson, 2015, Circulation. Cardiovascular genetics.

Exome Sequencing Identifies Pathogenic and Modifier Mutations in a Child With Sporadic Dilated Cardiomyopathy

Jared Evans, T. Olson, B. T. Larsen, 2015, Journal of the American Heart Association.

Identification of a metavinculin missense mutation, R975W, associated with both hypertrophic and dilated cardiomyopathy.

W. Edwards, S. Ommen, M. Ackerman, 2006, Molecular genetics and metabolism.

Late outcomes for surgical repair of supravalvar aortic stenosis.

H. Schaff, J. Dearani, H. Burkhart, 2012, The Annals of thoracic surgery.

A 30 kb deletion within the elastin gene results in familial supravalvular aortic stenosis.

S. Thibodeau, K. Csiszȧr, D. Driscoll, 1995, Human molecular genetics.

Compound heterozygous NOTCH1 mutations underlie impaired cardiogenesis in a patient with hypoplastic left heart syndrome

Timothy J. Nelson, M. de Andrade, Jared Evans, 2015, Human Genetics.

TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy.

Michael T. Zimmermann, E. Wieben, M. de Andrade, 2014, Human molecular genetics.

Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy.

L. Fananapazir, M. Ackerman, T. Doan, 2000, Journal of molecular and cellular cardiology.

Genomes or exomes: evaluation of cost, time and coverage

J. Kocher, S. Middha, T. Olson, 2011, Genome Biology.

Congenital heart defects in siblings with partial aneuploidy of chromosome 2p.

T. Olson, T. M. Sutton, Carolyn A Morris, 2006, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

Vitamin A deficiency in an infant with PAGOD syndrome

D. Babovic‐Vuksanovic, S. Kirmani, R. Gavrilova, 2009, American journal of medical genetics. Part A.

Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs

Angela R. Miller, L. Steinmetz, M. Hathcock, 2020, Nature Medicine.

Diagnostic Yield of Whole Exome Sequencing in Pediatric Dilated Cardiomyopathy

Jared Evans, T. Olson, Pamela A. Long, 2017, Journal of cardiovascular development and disease.

Modeling structural and functional deficiencies of RBM20 familial dilated cardiomyopathy using human induced pluripotent stem cells.

Timothy J. Nelson, A. Terzic, S. Reyes, 2016, Human molecular genetics.

Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy.

Timothy J. Nelson, A. Terzic, S. Reyes, 2014, Human molecular genetics.

Lone Atrial Fibrillation: Influence of Familial Disease on Gender Predilection

B. Tai, K. J. Herron, T. Olson, 2008, Journal of cardiovascular electrophysiology.

New-onset cough and fever in a toddler with stage 5 chronic kidney disease: Answers

T. Olson, Nathan C. Hull, Christian Hanna, 2021, Pediatric Nephrology.

Familial Incidence of Cardiovascular Malformations in Hypoplastic Left Heart Syndrome.

P. O’Leary, T. Olson, B. Eidem, 2015, The American journal of cardiology.

Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation.

Martin Bienengraeber, Andre Terzic, Timothy M Olson, 2006, Human molecular genetics.

Sodium channel mutations and susceptibility to heart failure and atrial fibrillation.

Jeffrey L. Anderson, R. Rodeheffer, Sandra P. Reyna, 2005, JAMA.

Electrocardiographic and Electrophysiologic Findings in Ebstein's Anomaly Pathophysiology, Diagnosis, and Management

T. Olson, C. Porter, 1993 .

gsSKAT: Rapid gene set analysis and multiple testing correction for rare‐variant association studies using weighted linear kernels

A. Whittemore, D. Schaid, J. Carpten, 2017, Genetic epidemiology.

CELSR1 Risk Alleles in Familial Bicuspid Aortic Valve and Hypoplastic Left Heart Syndrome

W. Bamlet, D. Hagler, Z. Fogarty, 2022, Circulation. Genomic and precision medicine.

Characterizing genetic variation of adrenergic signalling pathways in Takotsubo (stress) cardiomyopathy exomes

S. Middha, Jared Evans, A. Prasad, 2014, European journal of heart failure.

Homozygosity Mapping and Exome Sequencing Reveal GATAD1 Mutation in Autosomal Recessive Dilated Cardiomyopathy

Asha A. Nair, E. Wieben, H. Chai, 2011, Circulation. Cardiovascular genetics.

Pediatric Dilated Cardiomyopathy‐Associated LRRC10 (Leucine‐Rich Repeat–Containing 10) Variant Reveals LRRC10 as an Auxiliary Subunit of Cardiac L‐Type Ca2+ Channels

Marites T Woon, T. Kamp, Youngsook Lee, 2018, Journal of the American Heart Association.

Exome sequencing establishes diagnosis of Alström syndrome in an infant presenting with non‐syndromic dilated cardiomyopathy

Jared Evans, T. Olson, Pamela A. Long, 2015, American journal of medical genetics. Part A.

A genetic variant of the atrial natriuretic peptide gene is associated with cardiometabolic protection in the general community.

K. Bailey, R. Rodeheffer, M. Redfield, 2011, Journal of the American College of Cardiology.

Gene Mutations in Apical Hypertrophic Cardiomyopathy

J. Seidman, B. Maron, C. Seidman, 2005, Circulation.

Mapping a cardiomyopathy locus to chromosome 3p22-p25.

M. Keating, T. Olson, 1996, The Journal of clinical investigation.

Genetics of familial dilated cardiomyopathy

V. Michels, T. Olson, S. Menon, 2008 .

Mutations that alter the surface charge of alpha-tropomyosin are associated with dilated cardiomyopathy.

F. Whitby, V. Michels, T. Olson, 2001, Journal of molecular and cellular cardiology.

Cardiac ATP-Sensitive Potassium Channels and Associated Channelopathies

D. K. Arrell, A. Terzic, A. Alekseev, 2013 .

Advances in Arrhythmia and Electrophysiology Advances in Cardiac ATP-Sensitive K Channelopathies From Molecules to Populations

A. Terzic, A. Alekseev, S. Reyes, 2011 .

Characteristic Morphologies of the Bicuspid Aortic Valve in Patients with Genetic Syndromes.

D. Hagler, F. Cetta, Jonathan N. Johnson, 2017, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Atrial Natriuretic Peptide Genetic Variant rs5065 and Risk for Cardiovascular Disease in the General Community: A 9-Year Follow-Up Study

K. Bailey, R. Rodeheffer, M. Redfield, 2013, Hypertension.

Circulating Atrial Natriuretic Peptide Genetic Association Study Identifies a Novel Gene Cluster Associated With Stroke in Whites

G. Jenkins, R. Weinshilboum, Naresh Prodduturi, 2014, Circulation. Cardiovascular genetics.

Atrial Natriuretic Peptide Genetic Variant rs 5065 and Risk for Cardiovascular Disease in the General Community A 9-Year Follow-Up Study

K. Bailey, R. Rodeheffer, M. Redfield, 2022 .

Can antiheart autoantibodies predict disease risk in asymptomatic relatives of patients with dilated cardiomyopathy?

T. Olson, 2007, Nature Clinical Practice Cardiovascular Medicine.

Identification of Susceptibility Loci for Spontaneous Coronary Artery Dissection.

M. de Andrade, M. Kosel, S. Hayes, 2020, JAMA cardiology.

Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection.

N. Samani, P. Braund, X. Jouven, 2019, Journal of the American College of Cardiology.

Channelopathies of Cardiac Inwardly Rectifying Potassium Channels

A. Terzic, A. Jahangir, A. Alekseev, 2008 .

Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome

Timothy J. Nelson, K. Ocorr, R. Bodmer, 2020, eLife.

KATP channel Kir6.2 E23K variant overrepresented in human heart failure is associated with impaired exercise stress response

Bruce D. Johnson, A. Terzic, S. Reyes, 2009, Human Genetics.

P5-59: Influence of the common H558R-SCN5A sodium channel polymorphism on the electrocardiographic phenotype in a population-based study

M. Ackerman, R. Rodeheffer, S. Jacobsen, 2006 .

Myosin Light Chain Mutation Causes Autosomal Recessive Cardiomyopathy With Mid-Cavitary Hypertrophy and Restrictive Physiology

D. Driscoll, F. Whitby, Margaret L. Karst, 2002, Circulation.

Recessive MYH6 Mutations in Hypoplastic Left Heart With Reduced Ejection Fraction

Eric D Wieben, Michael T. Zimmermann, Jeanne L Theis, 2015, Circulation. Cardiovascular genetics.

Frequency of development of idiopathic dilated cardiomyopathy among relatives of patients with idiopathic dilated cardiomyopathy.

D. Driscoll, K. Ballman, F. Miller, 2003, The American journal of cardiology.

TFEB Overexpression, Not mTOR Inhibition, Ameliorates RagCS75Y Cardiomyopathy

Xueying Lin, A. V. Dvornikov, P. Zhu, 2021, International journal of molecular sciences.

De novo RRAGC mutation activates mTORC1 signaling in syndromic fetal dilated cardiomyopathy

M. Zimmermann, Jared Evans, T. Olson, 2016, Human Genetics.

X‐Linked Nonsyndromic Sinus Node Dysfunction and Atrial Fibrillation Caused by Emerin Mutation

Timothy M Olson, Margaret L. Karst, T. Olson, 2008, Journal of cardiovascular electrophysiology.

Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation

N. Samani, P. Braund, A. Hingorani, 2023, Nature Genetics.

Modeling GATAD1-Associated Dilated Cardiomyopathy in Adult Zebrafish

T. Olson, Xiaolei Xu, Jingchun Yang, 2016, Journal of cardiovascular development and disease.

Genome-Wide Association and Inheritance-Based Analyses Implicate Unconventional Myosin Genes in Hypoplastic Left Heart Syndrome

W. Bamlet, Z. Fogarty, T. Olson, 2022, Circulation. Genomic and precision medicine.

Confirmation of linkage of supravalvular aortic stenosis to the elastin gene on chromosome 7q.

D. Schaid, S. Thibodeau, M. Wallace, 1994, The American journal of cardiology.

Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case‐Control Sequencing Studies

Fredrik Wiklund, Jianfeng Xu, Rosalind Eeles, 2016, Genetic epidemiology.

Association of NPPA rs5065 Genetic Variant With Increased Cardiovascular Risk in the General USA Population

K. Bailey, R. Rodeheffer, J. Burnett, 2010 .

Functional studies of yeast actin mutants corresponding to human cardiomyopathy mutations

T. Doyle, T. Olson, E. Reisler, 2004, Journal of Muscle Research & Cell Motility.

Common Genetic Variant in PHACTR1/EDN1 Locus Is Associated with Spontaneous Coronary Artery Dissection Brief title: genetic variant rs9349379 associates with SCAD

Kovacic, C. Nelson, D. Fatkin, 2019 .

Modeling -Associated Dilated Cardiomyopathy in Adult Zebrafish.

T. Olson, Xiaolei Xu, Jingchun Yang, 2016 .

Modeling GATAD1-Associated Dilated Cardiomyopathy in Adult Zebrafish

T. Olson, Xiaolei Xu, Jingchun Yang, 2016, Journal of cardiovascular development and disease.

Genome-wide association meta-analysis of spontaneous coronary artery dissection reveals common variants and genes related to artery integrity and tissue-mediated coagulation

Rajiv, Xiaoping Zhou, N. Samani, 2022, medRxiv.

Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient‐Derived iPSC Model

Timothy J. Nelson, A. Terzic, S. Reyes, 2016, Clinical and translational science.

Exclusion of a primary gene defect at the HLA locus in familial idiopathic dilated cardiomyopathy.

D. Schaid, S. Thibodeau, P. Lundquist, 1995, Journal of medical genetics.

Aminoglycoside‐induced Translational Read‐through in Disease: Overcoming Nonsense Mutations by Pharmacogenetic Therapy

A. Terzic, A. Alekseev, L. Zingman, 2007, Clinical pharmacology and therapeutics.

Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity

K. Ocorr, R. Bodmer, A. Engler, 2022, medRxiv.

Bicuspid Aortic Valve in Infants, Children, and Adolescents: A Review for Primary Care Providers

D. Hagler, F. Cetta, Jonathan N. Johnson, 2021, Pediatrics in Review.

De novo RRAGC mutation activates mTORC1 signaling in syndromic fetal dilated cardiomyopathy

Michael T. Zimmermann, Jared Evans, T. Olson, 2016, Human Genetics.

Late outcomes for surgical repair of supravalvar aortic stenosis.

H. Schaff, J. Dearani, H. Burkhart, 2012, Annals of Thoracic Surgery.

LRRC10 is required to maintain cardiac function in response to pressure overload.

T. Kamp, Youngsook Lee, T. Hacker, 2016, American journal of physiology. Heart and circulatory physiology.

Lone Atrial Fibrillation: Influence of Familial Disease on Gender Predilection

B. Tai, T. Olson, Kathleen J. Herron, 2008, Journal of cardiovascular electrophysiology.

A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene.

S. Ekker, Xueying Lin, Yongyong Shi, 2016, JCI Insight.