J. M. Deforrest

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Fosinopril, a Phosphinic Acid Inhibitor of Angiotensin I Converting Enzyme: In Vitro and Preclinical In Vivo Pharmacology

T. Waldron, D. W. Cushman, J. M. Deforrest, 1989, Journal of cardiovascular pharmacology.

Continuous Angiotensin II Blockade throughout the Acute Phase of One‐Kidney Hypertension in the Dog

B. E. Watkins, J. O. Davis, R. Freeman, 1978, Circulation research.

Effects of the Oral Converting Enzyme Inhibitor (SQ 14225) on One-Kidney Hypertension in the Dog

B. E. Watkins, J. O. Davis, R. Freeman, 1978, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Effects of the Oral Converting Enzyme Inhibitor, SQ 14225, in a Model of Low Cardiac Output in Dogs

J. O. Davis, R. Freeman, G. Williams, 1979, Circulation research.

Comparisons in vitro, ex vivo, and in vivo of the actions of seven structurally diverse inhibitors of angiotensin converting enzyme (ACE).

G. Grover, F. Wang, D. W. Cushman, 1989, British journal of clinical pharmacology.

Chapter 6. Antihypertensive Agents

N. Trippodo, J. M. Deforrest, Edward W. Petriilo, 1990 .

Hemodynamic, Fluid, and Electrolyte Changes in Sodium‐Depleted, One‐Kidney, Renal Hypertensive Dogs

J. O. Davis, R. Freeman, J. M. Deforrest, 1979, Circulation research.

Differentiation of angiotensin-converting enzyme (ACE) inhibitors by their selective inhibition of ACE in physiologically important target organs.

F. Wang, D. W. Cushman, J. M. Deforrest, 1989, American journal of hypertension.

Renin release from filtering and nonfiltering kidneys stimulated by PGI2 and PGD2.

J. O. Davis, R. Freeman, G. Williams, 1979, The American journal of physiology.

Effects of lndomethacin, Renal Denervation, and Propranolol on Plasma Renin Activity in Conscious Dogs with Chronic Thoracic Caval Constriction

J. O. Davis, R. Freeman, J. M. Deforrest, 1981, Circulation research.

Hypertension Produced by Sodium Depletion and Unilateral Nephrectomy A New Experimental Model

R. Freeman, J. M. Deforrest, G. A. Stephens, 1980, Hypertension.

Preclinical Pharmacology of Zofenopril, an Inhibitor of Angiotensin I Converting Enzyme

T. Waldron, D. W. Cushman, J. M. Deforrest, 1989, Journal of cardiovascular pharmacology.

Effects of continuous converting enzyme blockade on renovascular hypertension in the rat.

B. E. Watkins, J. O. Davis, R. Freeman, 1979, The American journal of physiology.

Separate renal function studies in conscious dogs with renovascular hypertension.

B. E. Watkins, J. O. Davis, R. Freeman, 1978, The American journal of physiology.

Angiotensin II is a necessary component for the development of hypertension in the two kidney, one clip rat.

J. M. Deforrest, M. Antonaccio, J. S. Creekmore, 1982, The American journal of cardiology.

Sodium and angiotensin in the pathogenesis of experimental renovascular hypertension.

J. O. Davis, R. Freeman, G. Williams, 1981, The American journal of physiology.

Antihypertensive effects of 12 beta adrenoceptor antagonists in conscious spontaneously hypertensive rats: relationship to changes in plasma renin activity, heart rate and sympathetic nerve function.

J. M. Deforrest, E. Sybertz, J. High, 1986, The Journal of pharmacology and experimental therapeutics.

alpha-Hydroxy phosphinyl-based inhibitors of human renin.

C. Free, D. Patel, J. M. Deforrest, 1995, Journal of medicinal chemistry.

(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L -proline a novel orally active inhibitor of ACE.

D W Cushman, D. W. Cushman, J. M. Deforrest, 1988, Journal of medicinal chemistry.

(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme. 2. Terminal amino acid analogues of (S)-1-[6-amino-2 [[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline.

D W Cushman, V. Lee, D. W. Cushman, 1990, Journal of medicinal chemistry.

Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines.

D W Cushman, D. W. Cushman, J. M. Deforrest, 1988, Journal of medicinal chemistry.

Renal prostaglandins, renin release, and renal hemodynamic function in high renin states.

J. O. Davis, R. Freeman, G. Williams, 1980, Clinical and experimental hypertension.

Shear stress and aortic histamine synthesis.

J. M. Deforrest, T. M. Hollis, 1978, The American journal of physiology.

Effects of Indomethacin and Meclofenamate on Renin Release and Renal Hemodynamic Function during Chronic Sodium Depletion in Conscious Dogs

R. Freeman, T. Davis, J. M. Deforrest, 1980, Circulation research.

Circadian Changes in Plasma Renin Activity and Plasma Aldosterone Concentrationin Two‐Kidney Hypertensive Rats

B. E. Watkins, J. O. Davis, R. Freeman, 1979, Hypertension.

Blood Pressure Lowering and Renal Hemodynamic Effects of Fosinopril in Conscious Animal Models

T. Waldron, D. W. Cushman, J. M. Deforrest, 1990, Journal of cardiovascular pharmacology.

α-Hydroxy Phosphinyl-Based Inhibitors of Human Renin.

C. Free, D. Patel, J. M. Deforrest, 1996 .

Relationship between low intensity shear stress, aortic histamine formation, and aortic albumin uptake.

J. M. Deforrest, T. M. Hollis, J. DeForrest, 1980, Experimental and molecular pathology.

Ketomethylureas. A new class of angiotensin converting enzyme inhibitors.

E. Gordon, S. Natarajan, E. F. Sabo, 1988, Journal of enzyme inhibition.

Renal response to captopril in conscious dogs pretreated with indomethacin.

T. Waldron, J. M. Deforrest, M. Antonaccio, 1982, American Journal of Physiology.

Diol sulfonamides: A potent and novel class of inhibitors of human renin

M. Poss, T. Waldron, C. Free, 1993 .

Perinephritis hypertension in Macaca fascicularis (cynomolgus monkey): studies of the renin-angiotensin-aldosterone axis and renal hemodynamic function.

T. Waldron, C. Free, J. M. Deforrest, 1989, Journal of hypertension.