J. Courter

发表

Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors.

Alexander W. Sun, J. Sodroski, J. Mascola, 2012, Journal of medicinal chemistry.

Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization.

J. Sodroski, J. Mascola, Judith M. LaLonde, 2013, ACS medicinal chemistry letters.

Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18.

D. Dimitrov, J. Gershoni, E. Freire, 2011, Biochemistry.

Identification of a Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Variant Resistant to Cold Inactivation

J. Sodroski, M. Pancera, Amos B. Smith, 2009, Journal of Virology.

Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.

J. Sodroski, R. Wyatt, Judith M. LaLonde, 2008, Structure.

Tetrazine phototriggers: probes for peptide dynamics.

M. J. Tucker, R. Hochstrasser, J. Courter, 2010, Angewandte Chemie.

Di-Cysteine S,S-Tetrazine: A Potential Ultra-fast Photochemical Trigger to Explore the Early Events of Peptide/Protein Folding.

M. J. Tucker, R. Hochstrasser, J. Courter, 2012, Journal of photochemistry and photobiology. A, Chemistry.

Nonequilibrium dynamics of helix reorganization observed by transient 2D IR spectroscopy

M. J. Tucker, R. Hochstrasser, J. Courter, 2013, Proceedings of the National Academy of Sciences.

The 2013 Benjamin Franklin Medal in Chemistry presented to Jerrold Meinwald, Ph.D

Amos B. Smith, Joel R. Courter, J. Courter, 2015, J. Frankl. Inst..

Induction of a Tier-1-Like Phenotype in Diverse Tier-2 Isolates by Agents That Guide HIV-1 Env to Perturbation-Sensitive, Nonnative States

J. Sodroski, Amos B. Smith, Y. O’Malley, 2017, Journal of Virology.

Antibody-Dependent Cellular Cytotoxicity against Reactivated HIV-1-Infected Cells

J. Sodroski, D. Kaufmann, S. Kent, 2015, Journal of Virology.

Soluble CD4 and CD4-Mimetic Compounds Inhibit HIV-1 Infection by Induction of a Short-Lived Activated State

J. Sodroski, Liping Wang, Amy M. Princiotto, 2009, PLoS pathogens.

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins

J. Sodroski, D. Kaufmann, C. Tremblay, 2016, EBioMedicine.

Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity

J. Sodroski, D. Kaufmann, G. Shaw, 2015, EBioMedicine.

Small CD 4 Mimetics Prevent HIV-1 Uninfected Bystander CD 4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity

J. Sodroski, D. Kaufmann, G. Shaw, 2016 .

CD4 mimetics sensitize HIV-1-infected cells to ADCC

J. Sodroski, B. Haynes, D. Kaufmann, 2015, Proceedings of the National Academy of Sciences.

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

Peter D. Kwong, Joel R. Courter, Dennis R. Burton, 2014, Science.

Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.

J. Sodroski, Judith M. LaLonde, W. Hendrickson, 2016, ACS medicinal chemistry letters.

The design and synthesis of alanine-rich α-helical peptides constrained by an S,S-tetrazine photochemical trigger: a fragment union approach.

M. J. Tucker, R. Hochstrasser, J. Courter, 2014, The Journal of organic chemistry.

Design, synthesis, and photochemical validation of peptide linchpins containing the S,S-tetrazine phototrigger.

M. J. Tucker, R. Hochstrasser, J. Courter, 2012, Organic letters.

Contribution of Intrinsic Reactivity of the HIV-1 Envelope Glycoproteins to CD4-Independent Infection and Global Inhibitor Sensitivity

J. Sodroski, Liping Wang, M. Seaman, 2011, PLoS pathogens.

Transitions to and from the CD4-Bound Conformation Are Modulated by a Single-Residue Change in the Human Immunodeficiency Virus Type 1 gp120 Inner Domain

J. Sodroski, E. Freire, P. Kwong, 2009, Journal of Virology.

CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies

H. Liao, J. Sodroski, B. Haynes, 2014, Journal of Virology.

Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist

Peter D. Kwong, Wayne A. Hendrickson, Joel R. Courter, 2014, Accounts of chemical research.

Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening.

Young Do Kwon, Joel R Courter, Peter D Kwong, 2011, Bioorganic & medicinal chemistry.

An Inducible Cell-Cell Fusion System with Integrated Ability to Measure the Efficiency and Specificity of HIV-1 Entry Inhibitors

Alon Herschhorn, J. Sodroski, Amos B. Smith, 2011, PloS one.

Structure-activity relationships of tubulysin analogues.

A. Waight, P. Burke, P. Senter, 2020, Bioorganic & medicinal chemistry letters.

Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site

A. Debnath, Judith M. LaLonde, P. Kwong, 2014, PloS one.

CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies

J. Sodroski, B. Haynes, R. Wyatt, 2014, Journal of Virology.