N. Pras

发表

Artemisia annua L.: a source of novel antimalarial drugs

H. J. Woerdenbag, C. Lugt, N. Pras, 1990, Pharmaceutisch Weekblad.

Mucuna pruriens: Improvement of the biotechnological production of the anti-Parkinson drug L-dopa by plant cell selection

H. J. Woerdenbag, J. Visser, N. Pras, 1993, Pharmacy World and Science.

Production of secondary metabolites by bioconversion

H. J. Woerdenbag, N. Pras, 1999 .

Plant Cell Cultures, Secondary Product Accumulation

N. Pras, 2003 .

Deoxypodophyllotoxin 6-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum flavum involved in the biosynthesis of cytotoxic lignans

M. Petersen, N. Pras, A. Alfermann, 2001, Planta.

Cyclodextrins as a useful tool for bioconversions in plant cell biotechnology

H. J. Woerdenbag, N. Pras, W. Uden, 1994, Plant Cell, Tissue and Organ Culture.

Increased podophyllotoxin production in Podophyllum hexandrum cell suspension cultures after feeding coniferyl alcohol as a β-cyclodextrin complex

H. Frijlink, H. J. Woerdenbag, C. Lerk, 1990, Plant Cell Reports.

Bioconversion of naturally occurring precursors and related synthetic compounds using plant cell cultures.

N. Pras, 1992, Journal of biotechnology.

Cyclodextrin-facilitated bioconversion of 17 beta-estradiol by a phenoloxidase from Mucuna pruriens cell cultures.

C. Lerk, H. Frijlink, H. J. Woerdenbag, 1990, Phytochemistry.

Production of the new antimalarial drug artemisinin in shoot cultures of Artemisia annua L.

H. J. Woerdenbag, N. Pras, A. Alfermann, 1993, Plant Cell, Tissue and Organ Culture.

Stability of Artemisinin in Aqueous Environments: Impact on its Cytotoxic Action to Ehrlich Ascites Tumour Cells

H. J. Woerdenbag, H. Wikström, N. Pras, 1997, The Journal of pharmacy and pharmacology.

Volatile components from Anthriscus sylvestris (L.) Hoffm.

H. J. Woerdenbag, W. Quax, A. Koulman, 2002, Journal of chromatography. A.

Essential Oil Composition of Valeriana officinalis ssp. collina Cultivated in Bulgaria

R. Bos, N. Pras, H. Hendriks, 2000 .

Determination of valepotriates.

H. J. Woerdenbag, R. Bos, N. Pras, 2002, Journal of chromatography. A.

Linum Species (Flax): In Vivo and in Vitro Accumulation of Lignans and Other Metabolites

H. J. Woerdenbag, N. Pras, W. Uden, 1994 .

Structure-cytotoxicity relationships of some helenanolide-type sesquiterpene lactones.

H. J. Woerdenbag, H. Wikström, T. Schmidt, 1997, Journal of natural products.

Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines.

H. J. Woerdenbag, H. Kampinga, I. Merfort, 1994, Planta medica.

Structure -Cytotoxicity Relationships of a Series of Natural and Semi-Synthetic Simple Coumarins as Assessed in Two Human Tumour Cell Lines

H. J. Woerdenbag, O. Kayser, N. Pras, 1997, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Isolation, purification, and cytotoxicity of 5-methoxypodophyllotoxin, a lignan from a root culture of Linum flavum.

H. J. Woerdenbag, M. Harkes, N. Pras, 1992, Journal of natural products.

Progress in the research of artemisinin-related antimalarials: An update

Herman J. Woerdenbag, H. J. Woerdenbag, C. Lugt, 1994, Pharmacy World and Science.

Volatile constituents of Artemisia annua L. (Asteraceae)

H. J. Woerdenbag, R. Bos, N. Pras, 1993 .

The accumulation of podophyllotoxin-β-d-glucoside by cell suspension cultures derived from the conifer Callitris drummondii

N. Pras, W. Uden, Theo M. Maingré, 1990, Plant Cell Reports.

Plant cell factories as a source for anti-cancer lignans

M. Petersen, N. Pras, A. Alfermann, 2004, Phytochemistry Reviews.

Synthesis and cytotoxicity of novel lignans.

H. J. Woerdenbag, B. Feringa, N. Pras, 1995, Journal of medicinal chemistry.

Artemisinin-Derived Sesquiterpene Lactones as Potential Antitumour Compounds: Cytotoxic Action against Bone Marrow and Tumour Cells

H. J. Woerdenbag, H. Wikström, N. Pras, 1998, Planta medica.

Volatile Constituents of Artemisia annua

H. J. Woerdenbag, N. Pras, H. Hendriks, 1992 .

Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells.

H. J. Woerdenbag, H. Kampinga, N. Pras, 1993, Journal of natural products.

Production of the New Antimalarial Drug Artemisinin in Shoot Cultures ofArtemisia annua

H. J. Woerdenbag, N. Pras, A. Alfermann, 1992 .

Seasonal Variation of Artemisinin and its Biosynthetic Precursors in Plants of Artemisia annua of Different Geographical Origin: Proof for the Existence of Chemotypes

W. Quax, N. Pras, T E Wallaart, 2000, Planta medica.

ANALYSIS OF ARTEMISININ AND RELATED SESQUITERPENOIDS FROM ARTEMISIA-ANNUA L BY COMBINED GAS-CHROMATOGRAPHY MASS-SPECTROMETRY

H. J. Woerdenbag, J. Visser, R. Bos, 1991 .

Decreased helenalin-induced cytotoxicity by flavonoids from Arnica as studied in a human lung carcinoma cell line.

H. J. Woerdenbag, I. Merfort, T. Schmidt, 1995, Phytomedicine : international journal of phytotherapy and phytopharmacology.

H. J. Woerdenbag, C. Lugt, N. Pras, 1993, Planta medica.

Laboratory selection of Artemisia annua L. for high artemisinin yielding types

H. J. Woerdenbag, J. Visser, C. Lugt, 1991 .

Essential Oil of Croton flavens L. (Welensali), a Medicinal Plant from Curacao

H. J. Woerdenbag, L. de Jong-van den Berg, R. Bos, 2000 .

The large-scale isolation of deoxypodophyllotoxin from rhizomes of Anthriscus sylvestris followed by its bioconversion into 5-methoxypodophyllotoxin beta-D-glucoside by cell cultures of Linum flavum

H. J. Woerdenbag, N. Pras, W. Uden, 1997 .

A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris.

H. J. Woerdenbag, W. Quax, A. Koulman, 2003, Planta medica.

The bioconversion process of deoxypodophyllotoxin with Linum flavum cell cultures.

W. Quax, A. Koulman, N. Pras, 2003, Planta medica.

A fast and simple GC MS method for lignan profiling in Anthriscus sylvestris and biosynthetically related Plant species.

W. Quax, A. Koulman, N. Pras, 2001, Planta medica.

The production of podophyllotoxin and its 5-methoxy derivative through bioconversion of cyclodextrin-complexed desoxypodophyllotoxin by plant cell cultures

H. J. Woerdenbag, H. Wichers, N. Pras, 1995, Plant Cell, Tissue and Organ Culture.

Seasonal Variations of Artemisinin and its Biosynthetic Precursors in Tetraploid Artemisia annua Plants Compared with the Diploid Wild-Type

W. Quax, N. Pras, T. Wallaart, 1999, Planta medica.

Isolation of 3,4-dihydroxyphenylacetic acid produced from p-hydroxyphenylacetic acid by immobilized plant cells of Mucuna pruriens and its identification by liquid chromatography/mass spectrometry

N. Pras, A. Bruins, 1984 .

Occurrence of L-DOPA and dopamine in plants and cell cultures ofMucuna pruriens and effects of 2,4-d and NaCl on these compounds

J. Visser, H. Wichers, H. J. Huizing, 1993, Plant Cell, Tissue and Organ Culture.

Continuous production of the pharmaceutical 7,8-dihydroxy N-di-n-propyl 2-aminotetralin using a phenoloxidase from cell cultures of Mucuna pruriens

N. Pras, D. Dijkstra, A. Horn, 1990, Plant Cell, Tissue and Organ Culture.

Bioconversion of bi- and tri-cyclic monophenols by alginate-entrapped cells of Mucuna pruriens L. and by the partially purified Mucuna-phenoloxidase

N. Pras, D. Dijkstra, A. Horn, 1990, Plant Cell, Tissue and Organ Culture.

Bioconversion of para-substituted monophenolic compounds into corresponding catechols by alginate entrapped cells ofMucuna pruriens

A. Bruins, N. Pras, T. Malingré, 2004, Plant Cell, Tissue and Organ Culture.

Cytotoxicity and mode of action of aeroplysinin-1 and a related dienonefrom the sponge Aplysina aerophoba.

H. J. Woerdenbag, P. Proksch, R. Ebel, 1996, Journal of natural products.

The pharmaceutical exploration of cold water ascidians from the Netherlands: a possible source of ne

H. J. Woerdenbag, A. Koulman, N. Pras, 1999 .

Mucuna pruriens: In Vitro Production of L-DOPA

H. J. Huizing, N. Pras, H. Wichers, 1989 .

Kinetic aspects of the bioconversion of L‐tyrosine into L‐DOPA by cells of Mucuna pruriensL. Entrapped in different matrices

P. Hesselink, N. Pras, T. Malingré, 1989, Biotechnology and bioengineering.

The accumulation and isolation of coniferin from a high-producing cell suspension of Linum flavum L.

J. Visser, N. Pras, T. Malingré, 1991, Planta.

Stereochemistry-dependent cytotoxicity of some artemisinin derivatives.

H. J. Woerdenbag, H. Wikström, N. Pras, 1997, Journal of natural products.

High Peroxidase Activity In Cell Cultures of Artemisia Annua With Minute Artemisinin Contents

H. J. Woerdenbag, J. Visser, N. Pras, 1992 .

Cytotoxicity of natural ginseng glycosides and semisynthetic analogues.

G. B. Elyakov, H. J. Woerdenbag, A. Koulman, 1999, Planta medica.

The accumulation of podophyllotoxin-β-D-glucoside by cell suspension cultures derived from the conifer Callitris drummondii

N. Pras, T. Malingré, W. Uden, 2004, Plant Cell Reports.

The use of plant cell cultures for the production of podophyllotoxin and related lignans

M. Petersen, N. Pras, A. Alfermann, 2000 .

Improvement of the production of 5-methoxypodophyllotoxin using a new selected root culture of Linum flavum L.

N. Pras, T. Malingré, W. Uden, 1991, Plant Cell, Tissue and Organ Culture.

Detection and identification ofPodophyllotoxin produced by cell cultures derived from podophyllum hexandrum royle

J. Visser, N. Pras, T. Malingré, 1989, Plant Cell Reports.

Glucosylation of cyclodextrin-complexed podophyllotoxin by cell cultures of Linum flavum L.

H. J. Woerdenbag, N. Pras, W. Uden, 1993, Plant Cell, Tissue and Organ Culture.

Production of 5-methoxypodophyllotoxin in cell suspension cultures of Linum flavum L.

J. Mol, N. Pras, T. Malingré, 1990, Plant Cell, Tissue and Organ Culture.

On the improvement of the podophyllotoxin production by phenylpropanoid precursor feeding to cell cultures of Podophyllum hexandrum Royle

N. Pras, T. Malingré, W. Uden, 1990, Plant Cell, Tissue and Organ Culture.

Callitris spp. (Cypress Pine): In Vivo and In Vitro Accumulation of Podophyllotoxin and Other Secondary Metabolites

N. Pras, W. Uden, 1993 .

ISOLATION OF A PLANT-CELL CULTURE PRODUCT AND ITS IDENTIFICATION BY COMBINED LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY

N. Pras, A. Bruins, 1984 .

Isolation and identification of dihydroartemisinic acid from artemisia annua and its possible role in the biosynthesis of artemisinin

W. Quax, N. Pras, Pras, 1999, Journal of natural products.

Decreasing the load? Is a Multidisciplinary Multistep Medication Review in older people an effective intervention to reduce a patient's Drug Burden Index? Protocol of a randomised controlled trial

K. Taxis, H. Wouters, N. Pras, 2015, BMJ Open.

An Aporphine Alkaloid from Actinodaphne sesquipedalis

J. Visser, N. Pras, H. Hendriks, 1991 .