C. Bruggeman

P. Kitslaar, C. Bruggeman, R. Ezzahiri, 2003, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

CMV and Atherosclerosis

I. Vliegen, C. Bruggeman, F. Stassen, 2003 .

Chlamydophila pneumoniae (Chlamydia pneumoniae) accelerates the formation of complex atherosclerotic lesions in Apo E3-Leiden mice.

I. Vliegen, P. Kitslaar, C. Bruggeman, 2002, Cardiovascular research.

The Epstein-Barr Virus BILF1 Gene Encodes a G Protein-Coupled Receptor That Inhibits Phosphorylation of RNA-Dependent Protein Kinase

R. Leurs, M. Smit, D. Verzijl, 2005, Journal of Virology.

Comparison of five different immunoassays for the detection of Borrelia burgdorferi IgM and IgG antibodies.

C. Bruggeman, E. Nulens, V. Goossens, 2006, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Limited Role for C. pneumoniae, CMV and HSV-1 in Cerebral Large and Small Vessel Atherosclerosis

J. Lodder, C. Bruggeman, A. J. van der Ven, 2008, The open neurology journal.

Cytomegalovirus aggravates intimal hyperplasia in rats by stimulating smooth muscle cell proliferation.

C. Bruggeman, G. Kloppenburg, R. de Graaf, 2005, Microbes and infection.

Acute cytomegalovirus infection induces a subendothelial inflammation (endothelialitis) in the allograft vascular wall. A possible linkage with enhanced allograft arteriosclerosis.

K. Lemström, C. Bruggeman, P. Koskinen, 1994, The American journal of pathology.

C-reactive protein in peripheral arterial disease: relation to severity of the disease and to future cardiovascular events.

E. Twiss, P. Kitslaar, C. Bruggeman, 2005, Journal of vascular surgery.

The possible role of cytomegalovirus in atherogenesis.

M. V. van Dam-Mieras, C. Bruggeman, 1991, Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progres en virologie medicale.

Prophylaxis in the Rat

J. Bruning, C. Bruggeman, P. Koskinen, 2005 .

Original Contributions Active Cytomegalovirus Infection of Arterial Smooth Muscle Cells in Immunocompromised Rats

M. Daemen, C. Bruggeman, J. Bruning, 2005 .

Rat cytomegalovirus infection in kidney allograft recipients is associated with increased expression of intracellular adhesion molecule-1 vascular adhesion molecule-1, and their ligands leukocyte function antigen-1 and very late antigen-4 in the graft.

L. Krogerus, J. Kloover, C. Bruggeman, 2000, Transplantation.

Cytomegalovirus infection enhances the neointima formation in rat aortic allografts: effect of major histocompatibility complex class I and class II antigen differences.

C. Bruggeman, G. Grauls, J. Rozing, 1998, Transplantation.

Cytomegalovirus infection-enhanced cardiac allograft vasculopathy is abolished by DHPG prophylaxis in the rat.

K. Lemström, C. Bruggeman, P. Koskinen, 1997, Circulation.

Enhancement of transplantation‐associated atherosclerosis by CMV, which can be prevented by antiviral therapy in the form of HPMPC

E. Clercq, K. Lemström, C. Bruggeman, 1994, Transplant international : official journal of the European Society for Organ Transplantation.

CMV‐induced class II antigen expression in various rat organs

C. Bruggeman, J. Suni, R. Loginov, 1994, Transplant international : official journal of the European Society for Organ Transplantation.

Triple drug immunosuppression significantly reduces immune activation and allograft arteriosclerosis in cytomegalovirus-infected rat aortic allografts and induces early latency of viral infection.

K. Lemström, C. Bruggeman, P. Häyry, 1994, The American journal of pathology.

CMV-induced class II antigen expression in various rat organs

C. Bruggeman, J. Suni, R. Loginov, 1994 .

Cytomegalovirus and latency: an overview

C. Bruggeman, 1993, Virchows Archiv. B, Cell pathology including molecular pathology.

Inflammatory markers predict late cardiac events in patients who are exhausted after percutaneous coronary intervention.

M. D. de Baets, F. Bär, A. J. van der Ven, 2005, Atherosclerosis.

Towards understanding the pathophysiology of chronic rejection

T. Paavonen, A. Mennander, A. Miettinen, 1992, The clinical investigator.

Effects of cytomegalovirus infection and prolonged cold ischemia on chronic rejection of rat renal allografts

Prof. Dr. med. Gustav Steinhoff, C. Bruggeman, G. Grauls, 2000, Transplant international : official journal of the European Society for Organ Transplantation.

Tumor necrosis factor alpha promotes replication and pathogenicity of rat cytomegalovirus

Marian C. Horzinek, B. Haagmans, C. Bruggeman, 1994, Journal of virology.

The rat cytomegalovirus R32 gene encodes a virion-associated protein that elicits a strong humoral immune response in infected rats.

C. Bruggeman, C. Vink, E. Beuken, 1999, The Journal of general virology.

Evaluation of the rapid diagnostic test SDFK40 (Pf-pLDH/pan-pLDH) for the diagnosis of malaria in a non-endemic setting

E. Bottieau, J. Jacobs, P. Gillet, 2011, Malaria Journal.

Activation of protein kinase C enhances the infection of endothelial cells by human cytomegalovirus.

M. V. van Dam-Mieras, J. Heemskerk, C. Bruggeman, 1997, Virus research.

A rat cytomegalovirus infection model as a tool for immunotoxicity testing.

H. van Loveren, A. Osterhaus, J. Garssen, 1995, European journal of pharmacology.

Exploring the role of Chlamydia pneumoniae in cardiovascular disease: a narrative review.

C. Bruggeman, S. Sayed, T. Vainas, 2009, Drugs of today.

Rat cytomegalovirus open reading frame R44 is an early-late gene that encodes a nuclear protein

S. Kaptein, C. Bruggeman, C. Vink, 2001, Archives of Virology.

The Procoagulant Response of Cytomegalovirus Infected Endothelial Cells

V. V. van Hinsbergh, P. Bomans, M. V. van Dam-Mieras, 1992, Thrombosis and Haemostasis.

The effect of virus infection on the adherence of leukocytes or platelets to endothelial cells

C. Bruggeman, J. Endert, A. Muller, 1991, European journal of clinical investigation.

The effect of cytomegalovirus infection on the adherence of polymorphonuclear leucocytes to endothelial cells

C. Bruggeman, C. P. V. Boven, A. Span, 1989, European journal of clinical investigation.

Is pre-emptive strict isolation of patients at high risk of colonization with MRSA still required in low-prevalence countries?

F. V. van Tiel, P. Nelemans, C. Bruggeman, 2011, The Journal of hospital infection.

Prevalence and antibiotic resistance of commensal Streptococcus pneumoniae in nine European countries.

H. Goossens, F. Schellevis, M. Pringle, 2016, Future microbiology.

The r144 Major Histocompatibility Complex Class I-Like Gene of Rat Cytomegalovirus Is Dispensable for both Acute and Long-Term Infection in the Immunocompromised Host

M. Blok, J. Kloover, C. Bruggeman, 2000, Journal of Virology.

A rat cytomegalovirus strain with a disruption of the r144 MHC class I-like gene is attenuated in the acute phase of infection in neonatal rats

M. Blok, J. Kloover, C. Bruggeman, 2002, Archives of Virology.

Erratum: Impact of bacterial colonization on exhaled inflammatory markers in wheezing preschool children

Q. Jöbsis, J. Muris, O. V. van Schayck, 2012, Journal of breath research.

Impact of bacterial colonization on exhaled inflammatory markers in wheezing preschool children

Q. Jöbsis, J. Muris, O. V. van Schayck, 2012 .

Role of Peritoneal Macrophages in Cytomegalovirus-induced Acceleration of Autoimmune Diabetes in BB-rats

J. Hillebrands, C. Bruggeman, F. Klatter, 2003, Clinical & developmental immunology.

Infection and atherosclerosis. An alternative view on an outdated hypothesis.

C. Bruggeman, F. Stassen, T. Vainas, 2008, Pharmacological reports : PR.

Detection of amyloid beta aggregates in the brain of BALB/c mice after Chlamydia pneumoniae infection

H. Steinbusch, C. Schmitz, A. J. van der Ven, 2007, Acta Neuropathologica.

Chlamydia pneumoniae infection of brain cells: An in vitro study

H. Steinbusch, C. Bruggeman, G. Grauls, 2007, Neurobiology of Aging.

Entry of human cytomegalovirus into retinal pigment epithelial and endothelial cells by endocytosis.

E. Perret, M. V. van Dam-Mieras, B. Bodaghi, 1999, Investigative ophthalmology & visual science.

Detection of latent human cytomegalovirus in organ tissue and the correlation with serological status

J. Hooff, J. Geelen, C. Bruggeman, 1992 .

Detection of latent human cytomegalovirus in organ tissue and the correlation with serological status.

J. Hooff, J. Geelen, J. V. van Hooff, 1992, Transplant international : official journal of the European Society for Organ Transplantation.

C. Bruggeman, A. Muller, M. E. Slobbe-van Drunen, 2005, Archives of Virology.

Platelet-derived growth factor regulates cytomegalovirus infection-enhanced obliterative bronchiolitis in rat tracheal allografts

R. Krebs, K. Lemström, C. Bruggeman, 2004, Transplantation.

Cytomegalovirus infection enhances experimental obliterative bronchiolitis in rat tracheal allografts.

K. Lemström, C. Bruggeman, P. Koskinen, 1997, American journal of respiratory and critical care medicine.

Cytomegalovirus infection accelerates obliterative bronchiolitis of rat tracheal allografts

R. Krebs, K. Lemström, C. Bruggeman, 1996, Transplant international : official journal of the European Society for Organ Transplantation.

Serological markers of persistent C. trachomatis infections in women with tubal factor subfertility.

C. Bruggeman, J. D. den Hartog, J. Land, 2005, Human reproduction.

Unpredictable Effects of Rifampin as an Adjunctive Agent in Elimination of Rifampin-Susceptible and -Resistant Staphylococcus aureus Strains Grown in Biofilms

C. Bruggeman, E. Stobberingh, P. Beisser, 2010, Antimicrobial Agents and Chemotherapy.

Evaluation of a rapid one-step immunochromatographic test and two immunoenzymatic assays for the detection of anti-Treponema pallidum antibodies

F. V. van Tiel, C. Hoebe, J. Damoiseaux, 2008, Sexually Transmitted Infections.

Development of Transplant Arteriosclerosis: Effect of Timing of Infection and Recipient Genotype

J. Hillebrands, C. Bruggeman, F. Klatter, 2018 .

Interferon-β induces a long-lasting antiviral state in human respiratory epithelial cells.

G. Rohde, M. Dentener, C. Bruggeman, 2013, The Journal of infection.

The host immune response contributes to Haemophilus influenzae virulence.

E. Wouters, F. Franssen, G. Rohde, 2014, Respiratory medicine.

Chlamydia pneumoniae infection is not associated with chronic transplant dysfunction in a rat aortic allograft model.

C. Bruggeman, G. Kloppenburg, G. Grauls, 2007, Transplantation proceedings.

Effective treatment of experimental cytomegalovirus-induced encephalo-meningitis in immunocompromised rats with HPMPC.

W. Vanagt, J. Kloover, C. Bruggeman, 1997, Antiviral research.

Development of transplant arteriosclerosis after allogeneic aorta transplantation in the rat: influence of recipient genotype.

J. Hillebrands, C. Bruggeman, F. Klatter, 2001, Transplantation proceedings.

Detection of non-infectious conditions mimicking pneumonia in the intensive care setting: usefulness of bronchoalveolar fluid cytology.

N. Cobben, S. Wagenaar, G. Ramsay, 1999, Respiratory medicine.

The role of chlamydia genus-specific and species-specific IgG antibody testing in predicting tubal disease in subfertile women.

C. Bruggeman, J. D. den Hartog, J. Land, 2004, Human reproduction.

Cytomegalovirus infection enhances connective tissue growth factor mRNA expression in a rat model of chronic renal allograft rejection.

L. Krogerus, C. Bruggeman, P. Lindroos, 2001, Transplantation proceedings.

Chlamydia pneumoniae serology: comparing a commercial enzyme immunoassay and microimmunofluorescence test in patients with cardiovascular disease

P. Kitslaar, H. Kurvers, C. Bruggeman, 2003, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

The new immunosuppressive agent FK778 attenuates neointima formation in an experimental venous bypass graft model.

J. V. van Hooff, P. Kitslaar, C. Bruggeman, 2009, Vascular pharmacology.

One-step procedure for screening recombinant plasmids by size.

C. Bruggeman, C. Vink, E. Beuken, 1998, BioTechniques.

Chlamydia pneumoniae and screening for tubal factor subfertility.

C. Bruggeman, J. Land, J. Evers, 2001, Human reproduction.

Performance of five serological chlamydia antibody tests in subfertile women.

C. Bruggeman, J. Land, A. Kessels, 2003, Human reproduction.

Chlamydia antibody testing in screening for tubal factor subfertility: the significance of IgG antibody decline over time.

C. Bruggeman, J. Land, V. Goossens, 2002, Human reproduction.

The appropriateness of prescribing antibiotics in the community in Europe: study design

H. Goossens, F. Schellevis, M. Pringle, 2011, BMC infectious diseases.

TLR 9 KO MICE , HAPLOTYPES AND CPG INDICES IN CHLAMYDIA TRACHOMATIS INFECTION

S. Morré, A. Peña, P. Lundberg, 2010 .

Virally encoded G protein-coupled receptors: targets for potentially innovative anti-viral drug development.

R. Leurs, P. Casarosa, M. Smit, 2003, Current drug targets.

What determines the (in-) efficacy of a surveillance system to reduce surgical site infections after gastrointestinal surgery?

S. Breukink, C. Bruggeman, E. Stobberingh, 2014 .

Mutational analysis of the R33-encoded G protein-coupled receptor of rat cytomegalovirus: identification of amino acid residues critical for cellular localization and ligand-independent signalling.

R. Leurs, M. Smit, C. Bruggeman, 2004, The Journal of general virology.

Tuf mRNA rather than 16S rRNA is associated with culturable Staphylococcus aureus

A. Loonen, C. Bruggeman, P. Wolffs, 2015 .

Improved detection and quantification of mouse cytomegalovirus by real-time PCR.

I. Vliegen, C. Bruggeman, G. Grauls, 2003, Virus research.

Diagnostic Implications of Human Cytomegalovirus Immediate Early-1 and pp67 mRNA Detection in Whole-Blood Samples from Liver Transplant Patients Using Nucleic Acid Sequence-Based Amplification

M. Blok, Jaap M Middeldorp, C. Bruggeman, 2000, Journal of Clinical Microbiology.

Sensitive detection of cytomegalovirus infection in transplant recipients using nucleic acid sequence-based amplification.

M. Blok, M. Christiaans, Jaap M Middeldorp, 2000, Transplantation proceedings.

Nucleic acid sequence-based amplification: a new technique for monitoring cytomegalovirus infection in transplant recipients.

M. Blok, M. Christiaans, Jaap M Middeldorp, 1999, Transplantation proceedings.

Evaluation of a new method for early detection of active cytomegalovirus infections. A study in kidney transplant recipients

M. Blok, M. Christiaans, Jaap M Middeldorp, 1998, Transplant international : official journal of the European Society for Organ Transplantation.

Diagnostic Value of Monitoring Human Cytomegalovirus Late pp67 mRNA Expression in Renal-Allograft Recipients by Nucleic Acid Sequence-Based Amplification

M. Blok, M. Christiaans, Jaap M Middeldorp, 1998, Journal of Clinical Microbiology.

Different profiles of cytomegalovirus RNA transcripts and anti-cytomegalovirus IgM antibodies in renal transplant recipients.

Jaap M Middeldorp, C. Bruggeman, C. Vink, 2001, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Amplification Using Nucleic Acid Sequence-Based Samples from Liver Transplant Patients pp 67 mRNA Detection in Whole-Blood Cytomegalovirus Immediate Early-1 and Diagnostic Implications of Human

M. Blok, Jaap M Middeldorp, C. Bruggeman, 2000 .

Diagnostic Value of Nucleic-Acid-Sequence- Based Amplification for the Detection of Cytomegalovirus Infection in Renal and Liver Transplant Recipients

M. Blok, M. Christiaans, Jaap M Middeldorp, 2000, Intervirology.

Early detection of human cytomegalovirus infection after kidney transplantation by nucleic acid sequence-based amplification.

M. Blok, M. Christiaans, Jaap M Middeldorp, 1999, Transplantation.

Comparison of three different techniques for the isolation of viral RNA in sputum.

E. Wouters, F. Franssen, C. Bruggeman, 2014, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Vancomycin Dosing in Neutropenic Patients

A. Verbon, L. Stolk, C. Bruggeman, 2014, PloS one.

Cytomegalovirus enhance expression of growth factors during the development of chronic allograft nephropathy in rats

L. Krogerus, C. Bruggeman, R. Loginov, 2005, Transplant international : official journal of the European Society for Organ Transplantation.

Influence of a Cytomegalovirus Infection on Functions and Arachidonic Acid Metabolism of Rat Peritoneal Macrophages

C. Bruggeman, G. Grauls, W. Engels, 1989, Journal of leukocyte biology.

Rat cytomegalovirus replication in the salivary glands is exclusively confined to striated duct cells

J. Kloover, C. Bruggeman, P. Nieuwenhuis, 2000, Virchows Archiv.

Cytomegalovirus infection induces vascular wall inflammation and doubles arteriosclerotic changes in rat cardiac allografts.

M. Daemen, K. Lemström, C. Bruggeman, 1995, Transplantation proceedings.

Evaluation of phenotypic and molecular methods for identification of Streptococcus pneumoniae.

C. Bruggeman, E. Stobberingh, C. D. den Heijer, 2016, Future microbiology.

Effect of desferrioxamine (DFO) and calcium trinatrium diethylenetriaminepentaacetic acid (DTPA) on rat cytomegalovirus replication in vitro and in vivo.

J. Kloover, J. Činátl, C. Bruggeman, 1999, Antiviral research.

Nuclear import as a barrier to infection of human umbilical vein endothelial cells by human cytomegalovirus strain AD169.

M. V. van Dam-Mieras, C. Bruggeman, E. Speel, 1998, Virus research.

Expression of TGF-beta and PDGF-AA antigens and corresponding mRNAs in cytomegalovirus-infected rat kidney allografts.

L. Krogerus, C. Bruggeman, R. Loginov, 2003, Transplantation proceedings.

N‐acetylcysteine prevents neointima formation in experimental venous bypass grafts

C. Bruggeman, E. Rouwet, G. Kloppenburg, 2009, The British journal of surgery.

Complete DNA Sequence of the Rat Cytomegalovirus Genome

C. Bruggeman, C. Vink, E. Beuken, 2000, Journal of Virology.

Onset and duration of cytomegalovirus immediate early 1 mRNA expression in the blood of renal transplant recipients

M. Blok, M. Christiaans, P. Terporten, 2004, Journal of medical virology.

Intracellular thiol redox status affects rat cytomegalovirus infection of vascular cells.

M. V. van Dam-Mieras, C. Bruggeman, M. Persoons, 1997, Virus research.

Antimicrobial resistance among respiratory Haemophilus influenzae isolates from pulmonology services over a six-year period

C. Bruggeman, E. Stobberingh, F. Stassen, 2013, Scandinavian journal of infectious diseases.

Cytomegalovirus infection accelerates experimental obliterative bronchiolitis via platelet-derived growth factor upregulation.

K. Lemström, C. Bruggeman, P. Koskinen, 1997, Transplantation proceedings.

Human metapneumovirus in bronchoalveolar lavage fluid of critically ill patients with suspected pneumonia

C. Bruggeman, D. Bergmans, C. Linssen, 2012, Intensive Care Medicine.

The Rat Cytomegalovirus R33-Encoded G Protein-Coupled Receptor Signals in a Constitutive Fashion

R. Leurs, P. Casarosa, M. Smit, 2002, Journal of Virology.

Constitutive Fashion Protein-Coupled Receptor Signals in a The Rat Cytomegalovirus R 33-Encoded G

R. Leurs, P. Casarosa, M. Smit, 2001 .

Effect of CMV Infection on Chronic Rejection of Kidney Transplants

L. Krogerus, J. Kloover, C. Bruggeman, 2003 .

Rat cytomegalovirus-induced pneumonitis after allogeneic bone marrow transplantation: effective treatment with (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine

E. De Clercq, C. Bruggeman, F. Stals, 1993, Antimicrobial Agents and Chemotherapy.

Suppression of rat cytomegalovirus replication by antibodies against gamma interferon

Marian C. Horzinek, B. Haagmans, E. Claassen, 1994, Journal of virology.

Reply to: Effect of Macrolides on Peripheral Arterial Disease Depends on Patient Selection and Adequate Treatment. P.A. Krayenbuehl, P. Wiesli, T. Meier, G. Schulthess

J. Tordoir, P. Kitslaar, G. Schurink, 2005 .

L. Krogerus, J. Kloover, C. Bruggeman, 2000, Intervirology.

Direct induction of class II molecules by cytomegalovirus in rat heart microvascular endothelial cells is inhibited by ganciclovir (DHPG).

C. Bruggeman, P. Häyry, T. Lahtinen, 1994, Transplantation.

The ciprofloxacin target AUC : MIC ratio is not reached in hospitalized patients with the recommended dosing regimens.

C. Hoebe, A. Verbon, F. Nieman, 2013, British journal of clinical pharmacology.

Cytomegalovirus-encoded homologs of G protein-coupled receptors and chemokines.

M. Smit, C. Bruggeman, C. Vink, 2006, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

The r131 Gene of Rat Cytomegalovirus Encodes a Proinflammatory CC Chemokine Homolog which is Essential for the Production of Infectious Virus in the Salivary Glands

S. Kaptein, C. Bruggeman, C. Vink, 2004, Virus Genes.

Rat cytomegalovirus R89 is a highly conserved gene which expresses a spliced transcript.

C. Bruggeman, C. Vink, E. Beuken, 2000, Virus research.

Multiple organ involvement during experimental cytomegalovirus infection is associated with disseminated vascular pathology

C. Bruggeman, F. Stals, M. Persoons, 1998, The Journal of pathology.

Cytomegalovirus increases collagen synthesis in chronic rejection in the rat.

L. Krogerus, C. Bruggeman, J. Ahonen, 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Effect of cytomegalovirus on an experimental model of chronic renal allograft rejection under triple-drug treatment in the rat.

L. Krogerus, C. Bruggeman, O. Saarinen, 1997, Transplantation.

CMV increases inflammation and accelerates chronic rejection in rat kidney allografts.

L. Krogerus, C. Bruggeman, O. Saarinen, 1997, Transplantation proceedings.

CMV accelerates tubular apoptosis in a model of chronic renal allograft rejection.

L. Krogerus, C. Bruggeman, R. Loginov, 2001, Transplantation proceedings.

Induction of cyclo-oxygenase-2 by acute liver allograft rejection and cytomegalovirus infection in the rat

C. Bruggeman, T. Martelius, K. Höckerstedt, 2002, Transplant international : official journal of the European Society for Organ Transplantation.

CMV increases TNF-α expression in a rat kidney model of chronic rejection

L. Krogerus, C. Bruggeman, R. Loginov, 2003 .

Induction of cyclo‐oxygenase‐2 by acute liver allograft rejection and cytomegalovirus infection in the rat

C. Bruggeman, T. Martelius, K. Höckerstedt, 2002 .

Antiviral and immunomodulatory effects of desferrioxamine in cytomegalovirus-infected rat liver allografts with rejection.

H. Doerr, L. Krogerus, J. Činátl, 1999, Transplantation.

Clara cell protein in bronchoalveolar lavage fluid: a predictor of ventilator-associated pneumonia?

M. Drent, C. Bruggeman, D. Bergmans, 2009, Critical Care.

Dissemination of Rat Cytomegalovirus through Infected Granulocytes and Monocytes In Vitro and In Vivo

M. Harmsen, G. Molema, D. Meijer, 2003, Journal of Virology.

Induction of endothelial cell procoagulant activity by cytomegalovirus infection.

M. V. van Dam-Mieras, C. Bruggeman, R. Zwaal, 1987, Thrombosis research.

Surgical site infections: how high are the costs?

F. V. van Tiel, C. Bruggeman, A. V. van Asselt, 2009, The Journal of hospital infection.

The R33 G Protein-Coupled Receptor Gene of Rat Cytomegalovirus Plays an Essential Role in the Pathogenesis of Viral Infection

C. Bruggeman, C. Vink, P. Beisser, 1998, Journal of Virology.

The molecular evolution of methicillin-resistant Staphylococcus aureus.

A. Friedrich, C. Bruggeman, C. Vink, 2007, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

CMV DNA levels and CMV gB subtypes in ART-naive HAART-treated patients: a 2-year follow-up study in The Netherlands

A. Verbon, C. Bruggeman, P. Wolffs, 2009, AIDS.

Chemokines and chemokine receptors encoded by cytomegaloviruses.

H. Lavreysen, C. Bruggeman, C. Vink, 2008, Current topics in microbiology and immunology.

Molecular epidemiology of Pneumocystis jiroveci in human immunodeficiency virus-positive and -negative immunocompromised patients in The Netherlands.

C. Bruggeman, C. Linssen, M. Vanspauwen, 2014, Journal of medical microbiology.

Generalized cytomegalovirus (CMV) infection and CMV-induced pneumonitis in the rat: combined effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and specific antibody treatment.

S. Wagenaar, C. Bruggeman, F. Stals, 1994, Antiviral research.

Influence of Temperature, Medium, and Storage Duration on Chlamydia trachomatis DNA Detection by PCR

F. V. van Tiel, C. Hoebe, C. Bruggeman, 2012, Journal of Clinical Microbiology.

Widespread presence of cytomegalovirus DNA in tissues of healthy trauma victims.

C. Bruggeman, R. Slobbe, R. Hendrix, 1997, Journal of clinical pathology.

Direct induction of MHC class I, but not class II, expression on endothelial cells by cytomegalovirus infection.

M. Daha, C. Bruggeman, L. van Es, 1989, Transplantation.

Treatment of experimental cytomegalovirus infections with acyclovir

C. Bruggeman, J. Endert, W. Engels, 2005, Archives of Virology.

Infection of laboratory rats with a new cytomegalo-like virus

C. Bruggeman, C. P. V. Boven, G. Majoor, 2005, Archives of Virology.

Isolation of a cytomegalovirus-like agent from wild rats

C. Bruggeman, C. P. V. Boven, P. Dormans, 2005, Archives of Virology.

Herpes simplex virus load in bronchoalveolar lavage fluid is related to poor outcome in critically ill patients

P. Terporten, M. Drent, C. Bruggeman, 2008, Intensive Care Medicine.

Alterations of the functional state of peritoneal macrophages during rat cytomegalovirus infection in vivo

C. Bruggeman, C. P. V. Boven, M. Hendrix, 1986 .

Cytomegalovirus infection-enhanced chronic kidney allograft rejection is linked with intercellular adhesion molecule-1 expression.

K. Lemström, Serdar Yilmaz, C. Bruggeman, 1996, Kidney international.

Increased frequency of CMV infection in HLA-DR7 matched renal allograft recipients

J. Hooff, F. Nieman, C. Bruggeman, 1993, The Lancet.

IgM antibody detection of ppUL80a and ppUL32 by immunoblotting: An early parameter for recurrent cytomegalovirus infection in renal transplant recipients

M. Christiaans, T. Lazzarotto, M. Landini, 1996, Journal of medical virology.

Risk factors for cytomegalovirus infection and disease in renal transplant recipients: HLA-DR7 and triple therapy

M. Christiaans, J. Hooff, F. Nieman, 1994, Transplant international : official journal of the European Society for Organ Transplantation.

Risk factors for cytomegalovirus infection and disease in renal transplant recipients: HLA-DR7 and triple therapy

M. Christiaans, J. Hooff, F. Nieman, 1994, Transplant international : official journal of the European Society for Organ Transplantation.

Chapter 7 High herpes simplex virus load in bronchoalveolar lavage fluid is related to poor outcome in critically ill patients

P. Terporten, C. Bruggeman, C. Vink, 2008 .

TLR9 KO mice, haplotypes and CPG indices in Chlamydia trachomatis infection.

S. Morré, A. Peña, P. Lundberg, 2009, Drugs of today.

A 12 year (1998-2009) antibiotic resistance surveillance of Klebsiella pneumoniae collected from intensive care and urology patients in 14 Dutch hospitals.

C. Bruggeman, E. Stobberingh, P. Beisser, 2011, The Journal of antimicrobial chemotherapy.

Rat cytomegalovirus: induction of and sensitivity to interferon.

C. V. van Boven, H. Schellekens, C. Bruggeman, 1983, Antiviral research.

Comparative activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against rat cytomegalovirus infection in vitro and in vivo

E. De Clercq, E. Clercq, C. Bruggeman, 1991, Antimicrobial Agents and Chemotherapy.

Human cytomegalovirus induces a cellular deoxyguanosine kinase, also interacting with Acyclovir

C. Bruggeman, C. P. V. Boven, P. Dormans, 1984 .

Importance of Baseline Prognostic Factors With Increasing Time Since Initiation of Highly Active Antiretroviral Therapy: Collaborative Analysis of Cohorts of HIV-1-Infected Patients

Anne M Johnson, A. Trkola, J. Sterne, 2007, Journal of acquired immune deficiency syndromes.

Persistent rat cytomegalovirus (RCMV) infection of the salivary glands contributes to the anti-RCMV humoral immune response.

J. Kloover, C. Bruggeman, C. Vink, 2002, Virus research.

Lack of Evidence for the Role of Human Adenovirus‐36 in Obesity in a European Cohort

R. Loos, C. Hoebe, S. Rensen, 2011, Obesity.

Cytomegalovirus and atherogenesis.

C. Bruggeman, H. Marjorie, G. Nelissen-Vrancken, 1999, Antiviral research.

The Maastricht strain and England strain of rat cytomegalovirus represent different betaherpesvirus species rather than strains.

S. Kaptein, C. Bruggeman, C. Vink, 1998, Virology.

Cytomegalovirus infection is associated with increased inflammation and severe bile duct damage in rat liver allografts

L. Krogerus, C. Bruggeman, T. Martelius, 1998, Hepatology.

Rat cytomegalovirus infection and chronic kidney allograft rejection

K. Lemström, C. Bruggeman, P. Koskinen, 1996, Transplant international : official journal of the European Society for Organ Transplantation.

Cytomegalovirus-Mediated Upregulation of Chemokine Expression Correlates with the Acceleration of Chronic Rejection in Rat Heart Transplants

C. Corless, J. Nelson, C. Kreklywich, 2003, Journal of Virology.

Microbiology of surgical site infections after gastrointestinal surgery in the south region of The Netherlands.

F. V. van Tiel, S. Breukink, C. Bruggeman, 2014, Future microbiology.

Prevention of cytomegalovirus infection-enhanced experimental obliterative bronchiolitis by antiviral prophylaxis or immunosuppression in rat tracheal allografts.

K. Lemström, C. Bruggeman, P. Koskinen, 2001, American journal of respiratory and critical care medicine.

Cross-sectional study on surveillance of surgical site infections after vascular surgery.

S. Breukink, J. Penders, C. Bruggeman, 2013, Future microbiology.

Prevalence and resistance of commensal Staphylococcus aureus, including meticillin-resistant S aureus, in nine European countries: a cross-sectional study.

Herman Goossens, Mike Pringle, H. Goossens, 2013, The Lancet. Infectious diseases.

Structure of the rat cytomegalovirus genome termini

C. Bruggeman, C. Vink, E. Beuken, 1996, Journal of virology.

Cytomegalovirus infection-enhanced allograft arteriosclerosis is prevented by DHPG prophylaxis in the rat.

K. Lemström, C. Bruggeman, P. Koskinen, 1994, Circulation.

Occupational risk of human Cytomegalovirus and Parvovirus B19 infection in female day care personnel in the Netherlands; a study based on seroprevalence

C. Hoebe, C. Bruggeman, F. Stelma, 2009, European Journal of Clinical Microbiology & Infectious Diseases.

The rat cytomegalovirus R78 G protein-coupled receptor gene is required for production of infectious virus in the spleen.

K. Savelkouls, S. Kaptein, C. Bruggeman, 2003, The Journal of general virology.

Deletion of the R78 G Protein-Coupled Receptor Gene from Rat Cytomegalovirus Results in an Attenuated, Syncytium-Inducing Mutant Strain

C. Bruggeman, C. Vink, P. Beisser, 1999, Journal of Virology.

Cloning and functional characterization of the origin of lytic-phase DNA replication of rat cytomegalovirus.

C. Bruggeman, C. Vink, E. Beuken, 1997, The Journal of general virology.

Cloning and sequence analysis of the genes encoding DNA polymerase, glycoprotein B, ICP18.5 and major DNA-binding protein of rat cytomegalovirus.

C. Bruggeman, C. Vink, R. Slobbe, 1996, The Journal of general virology.

Association of cytomegalovirus and other pathogens with frailty and diabetes mellitus, but not with cardiovascular disease and mortality in psycho-geriatric patients; a prospective cohort study

C. Hoebe, P. Nelemans, A. Verbon, 2013, Immunity & Ageing.

The rat cytomegalovirus homologue of parvoviral rep genes, r127, encodes a nuclear protein with single- and double-stranded DNA-binding activity that is dispensable for virus replication.

S. Kaptein, C. Bruggeman, C. Vink, 2004, The Journal of general virology.

CYTOMEGALOVIRUS INFECTION, VIRAL DNA, AND IMMEDIATE EARLY-1 GENE EXPRESSION IN REJECTING RAT LIVER ALLOGRAFTS1

M. Blok, C. Bruggeman, T. Martelius, 2001, Transplantation.

Synergistic effect of Toll-like receptor 4 and CD14 polymorphisms on the total atherosclerosis burden in patients with peripheral arterial disease.

S. Morré, A. Peña, P. Kitslaar, 2006, Journal of vascular surgery.

Improving sexual health for HIV patients by providing a combination of integrated public health and hospital care services; a one-group pre- and post test intervention comparison

C. Hoebe, H. Vrijhoef, C. Bruggeman, 2012, BMC Public Health.

Biology of rat cytomegalovirus infection.

C. V. van Boven, C. Bruggeman, F. Bosman, 1985, Intervirology.

Rapid identification of bacteria by real-time amplification and sequencing of the 16S rRNA gene.

I. Vliegen, C. Bruggeman, C. Vink, 2006, Journal of microbiological methods.

A Real-Time PCR-Based Semi-Quantitative Breakpoint to Aid in Molecular Identification of Urinary Tract Infections

C. Bruggeman, E. Stobberingh, P. Wolffs, 2013, PloS one.

Compartmentalization of acyclovir-resistant varicella zoster virus: implications for sampling in molecular diagnostics.

C. Bruggeman, P. Wolffs, I. V. van Loo, 2011, Clinical Infectious Diseases.

Cytomegalovirus infection induces vascular injury in the rat.

C. V. van Boven, C. Bruggeman, G. Grauls, 1992, Atherosclerosis.

Induction of vascular adhesion protein-1 during liver allograft rejection and concomitant cytomegalovirus infection in rats.

S. Jalkanen, M. Salmi, H. Wu, 2000, The American journal of pathology.

Murine cytomegalovirus infection directs macrophage differentiation into a pro-inflammatory immune phenotype: implications for atherogenesis.

I. Vliegen, C. Bruggeman, F. Stassen, 2004, Microbes and infection.

An animal model for therapeutic intervention studies of CMV infection in the immunocompromised host

C. Bruggeman, C. P. V. Boven, F. Stals, 2005, Archives of Virology.

Chlamydia pneumoniae Serology Is Associated With Thrombosis-Related but Not With Plaque-Related Microembolization During Carotid Endarterectomy

W. Mess, J. Tordoir, P. Kitslaar, 2002, Stroke.

Haemophilus influenzae increases the susceptibility and inflammatory response of airway epithelial cells to viral infections

C. Bruggeman, F. Stassen, F. Gulraiz, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Infections with mimivirus in patients with chronic obstructive pulmonary disease.

E. Wouters, D. Raoult, F. Franssen, 2012, Respiratory medicine.

Enhancement of cytomegalovirus infection and acute rejection after allogeneic lung transplantation in the rat.

A. Haverich, Prof. Dr. med. Gustav Steinhoff, M. Lohmann‐Matthes, 1996, Transplantation.

CYTOMEGALOVIRUS DIRECTLY ENHANCES MHC CLASS I AND INTERCELLULAR ADHESION MOLECULE‐1 EXPRESSION ON CULTURED PROXIMAL TUBULAR EPITHELIAL CELLS

M. Daha, C. Bruggeman, L. van Es, 1993, Transplantation.

CMV induced vascular injury: an electron-microscopic study in the rat.

P. Frederik, C. Bruggeman, G. Grauls, 1993, In vivo.

Cytomegalovirus induces class II expression in rat heart endothelial cells.

C. Bruggeman, P. H. van der Meide, R. Loginov, 1993, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Reactivation of cytomegalovirus with acute rejection and cytomegalovirus infection with obliterative bronchiolitis in rat lung allografts.

K. Yagyu, Prof. Dr. med. Gustav Steinhoff, C. Bruggeman, 1993, Transplantation proceedings.

Reactivation of rat cytomegalovirus in lung allografts: an experimental and immunohistochemical study in rats.

K. Yagyu, H. Matsumoto, Prof. Dr. med. Gustav Steinhoff, 1992, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Cytomegalovirus induced PMN adherence in relation to an ELAM-1 antigen present on infected endothelial cell monolayers.

C. Bruggeman, A. Miltenburg, W. Mullers, 1991, Immunology.

Passive transfer of cytomegalovirus by cardiac and renal organ transplants in a rat model.

C. V. van Boven, C. Bruggeman, P. J. Van Breda Vriesman, 1986, Transplantation.

CMV increases tubular apoptosis through the TNF-alpha-TNF-R1 pathway in a rat model of chronic renal allograft rejection.

L. Krogerus, C. Bruggeman, R. Loginov, 2008, Transplant immunology.

Interleukin-1B (IL-1B) and interleukin-1 receptor antagonist (IL-1RN) gene polymorphisms are not associated with tubal pathology and Chlamydia trachomatis-related tubal factor subfertility.

S. Morré, A. Peña, C. Bruggeman, 2003, Human reproduction.

Chlamydia trachomatis in subfertile women undergoing uterine instrumentation. Screen or treat?

C. Bruggeman, J. Land, J. Evers, 2002, Human reproduction.

Molecular Mimicry by Cytomegaloviruses

C. Bruggeman, C. Vink, P. Beisser, 2000, Intervirology.

The role that the functional Asp299Gly polymorphism in the toll-like receptor-4 gene plays in susceptibility to Chlamydia trachomatis-associated tubal infertility.

S. Morré, A. Peña, C. Bruggeman, 2003, The Journal of infectious diseases.

The role of cytomegalovirus-encoded homologs of G protein-coupled receptors and chemokines in manipulation of and evasion from the immune system.

R. Leurs, M. Smit, C. Bruggeman, 2001, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Constitutive Signaling of the Human Cytomegalovirus-encoded Receptor UL33 Differs from That of Its Rat Cytomegalovirus Homolog R33 by Promiscuous Activation of G Proteins of the Gq, Gi, and Gs Classes*

R. Leurs, P. Casarosa, M. Smit, 2003, Journal of Biological Chemistry.

Deletion of the R78 G protein-coupled receptor gene from rat cytomegalovirus results in an attenuated, syncytium-inducing mutant strain.

C. Bruggeman, C. Vink, P. Beisser, 1999, Journal of virology.

Enhancement of cytomegalovirus infection and acute rejection after allogeneic lung transplantation in the rat: virus-induced expression of major histocompatibility complex class II antigens.

A. Haverich, Prof. Dr. med. Gustav Steinhoff, T. Wagner, 1996, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

The development and characterization of monoclonal antibodies against rat cytomegalovirus induced antigens

C. Bruggeman, J. Bruning, P. Dormans, 2005, Archives of Virology.

Acceleration of the direct identification of Staphylococcus aureus versus coagulase-negative staphylococci from blood culture material: a comparison of six bacterial DNA extraction methods

A. Loonen, A. V. D. van den Brule, C. Bruggeman, 2010, European Journal of Clinical Microbiology & Infectious Diseases.

Efficacy of IFN-λ1 to Protect Human Airway Epithelial Cells against Human Rhinovirus 1B Infection

G. Rohde, M. Dentener, C. Bruggeman, 2014, PloS one.

Trends in Antibiotic Prescribing in Adults in Dutch General Practice

C. Hoebe, A. Verbon, J. Cals, 2012, PloS one.

Comparison of urine samples and penile swabs for detection of human papillomavirus in HIV-negative Dutch men

W. Quint, C. Hoebe, C. Bruggeman, 2016, Sexually Transmitted Infections.

point-of-care testing trachomatis Chlamydia Alarmingly poor performance in

C. Hoebe, S. Morré, P. Terporten, 2022 .

Virus induced adherence of monocytes to endothelial cells.

C. V. van Boven, C. Bruggeman, J. Endert, 1989, FEMS microbiology immunology.

FK778 Attenuates Cytomegalovirus-Enhanced Vein Graft Intimal Hyperplasia in a Rat Model

J. V. van Hooff, C. Bruggeman, G. Kloppenburg, 2009, Intervirology.

Human heat shock protein 60 stimulates vascular smooth muscle cell proliferation through Toll-like receptors 2 and 4.

P. Kitslaar, C. Bruggeman, G. Kloppenburg, 2006, Microbes and infection.

Generation of polyclonal antibodies directed against G protein-coupled receptors using electroporation-aided DNA immunization.

H. Lavreysen, M. D. de Baets, M. Losen, 2008, Journal of pharmacological and toxicological methods.

Chlamydia pneumoniae is a likely risk factor for ischemic stroke in young patients.

J. Lodder, C. Bruggeman, C. Faber, 2004, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

Is the standard dose of amoxicillin-clavulanic acid sufficient?

A. Verbon, L. Stolk, C. Bruggeman, 2014, BMC Pharmacology and Toxicology.

Test Characteristics of Acridine Orange, Gram, and May-Grünwald-Giemsa Stains for Enumeration of Intracellular Organisms in Bronchoalveolar Lavage Fluid

M. Drent, F. Nieman, C. Bruggeman, 1999, Journal of Clinical Microbiology.

Antimicrobial resistance and molecular typing of Staphylococcus aureus bloodstream isolates from hospitals in Peru.

J. Jacobs, C. Bruggeman, E. Stobberingh, 2012, The Journal of infection.

Secondary prevention of atherosclerosis through chlamydia pneumoniae eradication (SPACE Trial): a randomised clinical trial in patients with peripheral arterial disease.

J. Tordoir, P. Kitslaar, G. Schurink, 2005, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

Cytomegalovirus‐enhanced development of transplant arteriosclerosis in the rat; effect of timing of infection and recipient responsiveness

J. Hillebrands, C. Bruggeman, F. Klatter, 2005, Transplant international : official journal of the European Society for Organ Transplantation.

Bronchoalveolar lavage fluid differential cell count. How many cells should be counted?

M. Drent, F. Nieman, C. Bruggeman, 2002, Analytical and quantitative cytology and histology.

Differential cell analysis of cytocentrifuged bronchoalveolar fluid samples affected by the area counted.

S. Wagenaar, J. Jacobs, M. Drent, 2000, Analytical and quantitative cytology and histology.

Cytocentrifugation conditions affecting the differential cell count in bronchoalveolar lavage fluid.

S. Wagenaar, M. Drent, F. Nieman, 2000, Analytical and quantitative cytology and histology.

Developments for improved diagnosis of bacterial bloodstream infections

A. Loonen, C. Bruggeman, P. Wolffs, 2014, European Journal of Clinical Microbiology & Infectious Diseases.

Cytomegalovirus induces interstitial lung disease in allogeneic bone marrow transplant recipient rats independent of acute graft-versus-host response.

S. Wagenaar, A. Haverich, Prof. Dr. med. Gustav Steinhoff, 1996, Laboratory investigation; a journal of technical methods and pathology.

Initial endothelial injury and cytomegalovirus infection accelerate the development of allograft arteriosclerosis.

C. Bruggeman, G. Grauls, M. Yin, 1995, Transplantation proceedings.

Triple-drug immunosuppression significantly reduces chronic rejection in noninfected and RCMV-infected rats.

K. Lemström, C. Bruggeman, P. Koskinen, 1994, Transplantation proceedings.

Cytomegalovirus infection enhances allograft arteriosclerosis in the rat.

K. Lemström, C. Bruggeman, P. Häyry, 1993, Transplantation proceedings.

Reactivation of latent rat cytomegalovirus by a combination of immunosuppression and administration of allogeneic immunocompetent cells.

C. V. van Boven, C. Bruggeman, P. J. Van Breda Vriesman, 1989, Transplantation.

The effect of cytomegalovirus infection on renal allograft function and rejection in a rat model.

C. Bruggeman, P. J. Van Breda Vriesman, J. Bruning, 1989, Transplantation.

Rat cytomegalovirus can be transferred by bone marrow cells but does not affect the course of acute graft-versus-host disease.

C. Bruggeman, P. J. Van Breda Vriesman, G. Bos, 1989, Transplantation proceedings.

Susceptibility of peritoneal macrophages to rat cytomegalovirus infection

C. Bruggeman, C. P. V. Boven, G. Grauls, 1985 .

Combinations of ganciclovir and antibody for experimental CMV infections.

S. Wagenaar, W. Vanagt, J. Kloover, 1996, Antiviral research.

Pathogenicity: animal models.

C. Bruggeman, F. Stals, F. Li, 1995, Scandinavian journal of infectious diseases. Supplementum.

Efficacy of HPMPC in the treatment of CMV infections in various animal models

J. Neyts, E. Clercq, C. Bruggeman, 1993 .

Replacing Traditional Diagnostics of Fecal Viral Pathogens by a Comprehensive Panel of Real-Time PCRs

C. Bruggeman, P. Wolffs, I. V. van Loo, 2011, Journal of Clinical Microbiology.

Impact of same-day antibiotic susceptibility testing on time to appropriate antibiotic treatment of patients with bacteraemia: a randomised controlled trial

A. Kessels, A. Verbon, C. Bruggeman, 2014, European Journal of Clinical Microbiology & Infectious Diseases.

Immune activation following cytomegalovirus infection: more important than direct viral effects in cardiovascular disease?

I. Vliegen, C. Bruggeman, F. Stassen, 2006, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Cytomegalovirus Alters the von Willebrand Factor Content in Human Endothelial Cells

C. Bruggeman, B. Schutte, A. Muller, 1988, Thrombosis and Haemostasis.

ELIMINATION OF DONOR-SPECIFIC ALLOREACTIVITY BY BONE MARROW CHIMERISM PREVENTS CYTOMEGALOVIRUS ACCELERATED TRANSPLANT VASCULAR SCLEROSIS IN RAT SMALL BOWEL TRANSPLANTS

J. Rabkin, C. Corless, J. Nelson, 1999 .

CMV causes bile duct destruction and arterial lesions in rat liver allografts.

H. Mäkisalo, L. Krogerus, C. Bruggeman, 1997, Transplantation Proceedings.

CMV increases TNF-alpha expression in a rat kidney model of chronic rejection.

L. Krogerus, C. Bruggeman, R. Loginov, 2003, Transplantation Proceedings.

Cytomegalovirus infection and vessel wall pathology.

M. V. van Dam-Mieras, C. Bruggeman, R. Vossen, 1996, Intervirology.

Chlamydia pneumoniae infection enhances microglial activation in atherosclerotic mice

H. Steinbusch, J. Lodder, C. Bruggeman, 2010, Neurobiology of Aging.