P. Lombardi

发表

A. Scovassi, Micol Tillhon, L. M. Guamán Ortiz, 2014, Molecules.

Substituted 1-[(benzofuran-2-YL)-phenylmethyl]-imidazoles as potent inhibitors of aromatase in vitro and in female rats in vivo

H. J. Smith, P. Lombardi, V. Pestellini, 1993, The Journal of Steroid Biochemistry and Molecular Biology.

Berberine: new perspectives for old remedies.

A. Scovassi, Micol Tillhon, L. M. Guamán Ortiz, 2012, Biochemical pharmacology.

Exemestane, a new steroidal aromatase inhibitor of clinical relevance.

P. Lombardi, 2002, Biochimica et biophysica acta.

Synthesis and biological evaluation of novel heteroring-annulated pyrrolino-tetrahydroberberine analogues as antioxidant agents.

S. Battistelli, P. Lombardi, A. Amicucci, 2018, Bioorganic & medicinal chemistry.

Multiple Effects of Berberine Derivatives on Colon Cancer Cells

M. Savio, A. Scovassi, E. Prosperi, 2014, BioMed research international.

Biological activity and DNA Sequence Specificity of Synthetic Carbamoyl Analogues of Distamycin

M. Waring, C. Bailly, M. Dentini, 1997 .

Antitumor activity of NAX060: A novel semisynthetic berberine derivative in breast cancer cells

M. Provinciali, E. Pierpaoli, P. Lombardi, 2018, BioFactors.

A preliminary comparison between hydrogenase and oxygen as electron acceptors in irradiated aqueous dispersion of titanium dioxide

P. Lombardi, M. Ganadu, G. Lubinu, 2002 .

Abilities of berberine and chemically modified berberines to inhibit proliferation of pancreatic cancer cells.

Stephen L. Abrams, J. McCubrey, M. Libra, 2019, Advances in biological regulation.

Doxorubicin disaccharide analogue: apoptosis-related improvement of efficacy in vivo.

F. Zunino, G. Capranico, R. Supino, 1997, Journal of the National Cancer Institute.

Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells.

Maria Paola Costi, M. G. Monti, C. Frassineti, 2013, International journal of oncology.

Distamycin A and derivatives as synergic drugs in cisplatin-sensitive and -resistant ovarian cancer cells

Maria Paola Costi, M. G. Monti, C. Frassineti, 2011, Amino Acids.

Pyridine Derivative of the Natural Alkaloid Berberine as Human Telomeric G4-DNA Binder: A Solution and Solid-State Study.

M. Ferraroni, G. S. Kumar, P. Lombardi, 2020, ACS medicinal chemistry letters.

Antitumor effect of novel berberine derivatives in breast cancer cells.

M. Provinciali, E. Pierpaoli, P. Lombardi, 2013, BioFactors.

New anthracycline disaccharides. Synthesis of L-daunosaminyl-α(1 →4)-2-deoxy-L-rhamnosyl and of L-daunosaminyl-α(1 →4)-2-deoxy-L-fucosyl daunorubicin analogues

M. Berettoni, A. Cipollone, P. Lombardi, 1996 .

New developments in antitumor anthracyclines.

F. Zunino, G. Capranico, R. Supino, 1997, Pharmacology & therapeutics.

Probing the Efficiency of 13-Pyridylalkyl Berberine Derivatives to Human Telomeric G-Quadruplexes Binding: Spectroscopic, Solid State and In Silico Analysis

M. Ferraroni, P. Lombardi, P. Gratteri, 2022, International journal of molecular sciences.

Targeting human telomeric DNA quadruplex with novel berberrubine derivatives: insights from spectroscopic and docking studies

P. Lombardi, Suman Das, Sutanwi Bhuiya, 2019, Journal of biomolecular structure & dynamics.

Synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity via palladium-catalyzed heteroannulation of chiral arylpropargylic alcohols

M. Botta, V. Summa, F. Corelli, 1996 .

Total synthesis of thia analogues of clavulanic acid

P. Lombardi, F. Arcamone, G. Franceschi, 1979 .

Large scale preparation of enantiopure S-ketoprofen by biocatalysed kinetic resolution

P. Lombardi, G. Nicolosi, N. Antona, 2002 .

Heteroring-annulated pyrrolino-tetrahydroberberine analogues

P. Lombardi, G. Giorgi, G. Favi, 2017 .

From the penicillin to the nocardicin skeleton: an alternative route

P. Lombardi, F. Arcamone, G. Franceschi, 1979 .

4-tetrahydropyranthioazetidinyl phosphoranes: Versatile intermediates in the synthesis of 2-penems

A. Longo, P. Lombardi, G. Franceschi, 1981 .

Binding of Epstein-Barr virus nuclear antigen 1 to DNA: inhibition by distamycin and two novel distamycin analogues.

R. Gambari, P. Giacomini, A. Ciucci, 1994, European journal of pharmacology.

Calorimetry and thermal analysis studies on the binding of 13-phenylalkyl and 13-diphenylalkyl berberine analogs to tRNAphe

P. Lombardi, L. Franchini, Debipreeta Bhowmik, 2014, Journal of Thermal Analysis and Calorimetry.

“4,7-lactams”, intermediates for penems synthesis. I. skeletal conversion of penicillanic acid to (+)-2,2,5,5-tetramethyl-9-oxo-3-oxa-6-thia-azabicyclo[5,2,01,7]nonane

A. Longo, P. Lombardi, A. Crugnola, 1981 .

Synthesis of two distamycin analogues and their binding mode to d(CGCAAATTTGCG)2 in the 2:1 solution complexes as determined by two-dimensional 1H-NMR.

M. Conte, L. Mayol, P. Lombardi, 1995, Journal of medicinal chemistry.

Biophysical studies on the effect of the 13 position substitution of the anticancer alkaloid berberine on its DNA binding.

G. S. Kumar, P. Lombardi, Maidul Hossain, 2012, The journal of physical chemistry. B.

Synthesis of new 13-diphenylalkyl analogues of berberine and elucidation of their base pair specificity and energetics of DNA binding

G. S. Kumar, P. Lombardi, Debipreeta Bhowmik, 2014 .

Calorimetric insights into the interaction of novel berberrubine derivatives with human telomeric G-quadruplex DNA sequence

P. Lombardi, Asma Yasmeen Khan, G. Suresh Kumar, 2018, Journal of Thermal Analysis and Calorimetry.

Recognition of human telomeric G‐quadruplex DNA by berberine analogs: effect of substitution at the 9 and 13 positions of the isoquinoline moiety

P. Lombardi, Debipreeta Bhowmik, G. Suresh Kumar, 2015, Journal of molecular recognition : JMR.

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

Stephen L. Abrams, Li V. Yang, J. McCubrey, 2017, Aging.

Spectroscopic studies on the binding interaction of novel 13-phenylalkyl analogs of the natural alkaloid berberine to nucleic acid triplexes.

P. Lombardi, Debipreeta Bhowmik, G. Suresh Kumar, 2014, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

6-Methylenandrosta-1,4-diene-3,17-dione (FCE 24304): a new irreversible aromatase inhibitor.

P. Lombardi, E. di Salle, E. Salle, 1988, Journal of steroid biochemistry.

4-aminoandrostenedione derivatives: A novel class of irreversible aromatase inhibitors. Comparison with FCE 24304 and 4-hydroxyandrostenedione

R. D'Alessio, P. Lombardi, E. Di Salle, 1990, The Journal of Steroid Biochemistry and Molecular Biology.

Distamycin A and derivatives as synergic drugs in cisplatin-sensitive and -resistant ovarian cancer cells

Maria Paola Costi, M. G. Monti, C. Frassineti, 2012, Amino Acids.

Antimalarial activity of synthetic analogues of distamycin.

A. Crisanti, P. Lombardi, 1997, Pharmacology & therapeutics.

Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells-Power of nutraceuticals.

Stephen L. Abrams, J. McCubrey, M. Libra, 2017, Advances in biological regulation.

Evaluation of the immunomodulatory potential of diethyl dithiocarbamate derivatives.

J. Bernier, P. Neveu, S. Mansour, 1991, International journal of immunopharmacology.

EMQN best practice guidelines for the molecular genetic testing and reporting of chromosome 11p15 imprinting disorders: Silver–Russell and Beckwith–Wiedemann syndrome

R. Weksberg, Z. Tümer, P. Lapunzina, 2016, European Journal of Human Genetics.

Solution and Solid-State Analysis of Binding of 13-Substituted Berberine Analogues to Human Telomeric G-quadruplexes.

M. Ferraroni, A. Scovassi, P. Lombardi, 2016, Chemistry, an Asian journal.

Metformin influences drug sensitivity in pancreatic cancer cells.

Stephen L. Abrams, J. McCubrey, M. Libra, 2018, Advances in biological regulation.

Killing of tumor cells: a drama in two acts.

G. Mazzini, A. Scovassi, E. Prosperi, 2011, Biochemical pharmacology.

Effects of the MDM2 inhibitor Nutlin-3a on sensitivity of pancreatic cancer cells to berberine and modified berberines in the presence and absence of WT-TP53

J. McCubrey, M. Libra, A. Martelli, 2021, Advances in Biological Regulation.

Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals.

Stephen L. Abrams, Li V. Yang, J. McCubrey, 2018, Advances in biological regulation.

Effects of the MDM-2 inhibitor Nutlin-3a on PDAC cells containing and lacking WT-TP53 on sensitivity to chemotherapy, signal transduction inhibitors and nutraceuticals.

Stephen L. Abrams, J. McCubrey, S. M. Akula, 2019, Advances in biological regulation.

APR-246—The Mutant TP53 Reactivator—Increases the Effectiveness of Berberine and Modified Berberines to Inhibit the Proliferation of Pancreatic Cancer Cells

J. McCubrey, A. Martelli, L. Steelman, 2022, Biomolecules.

Antiangiogenic and antitumor activities of berberine derivative NAX014 compound in a transgenic murine model of HER2/neu-positive mammary carcinoma.

M. Provinciali, E. Pierpaoli, B. Bartozzi, 2015, Carcinogenesis.

Backbone and benzoyl mustard carrying moiety modifies DNA interactions of distamycin analogues.

A. Ciucci, S. Manzini, P. Lombardi, 1996, Nucleic acids research.

Abilities of berberine and chemically modified berberines to interact with metformin and inhibit proliferation of pancreatic cancer cells.

Stephen L. Abrams, J. McCubrey, S. M. Akula, 2019, Advances in biological regulation.

A new route to optically active 4-acyloxy azetidin-2-ones

P. Lombardi, G. Franceschi, A. Suarato, 1978 .

Role of 13-(di)phenylalkyl berberine derivatives in the modulation of the activity of human topoisomerase IB.

A. Desideri, M. Falconi, P. Lombardi, 2015, International journal of biological macromolecules.

A Rapid, Safe, and Convenient Procedure for the Preparation and Use of Diazomethane.

P. Lombardi, 1991 .

Potential application of berberine in the treatment of Escherichia coli sepsis

M. Provinciali, E. Pierpaoli, P. Lombardi, 2020, Natural product research.

Antimetastatic and Antitumor Activities of Orally Administered NAX014 Compound in a Murine Model of HER2-Positive Breast Cancer

M. Provinciali, E. Pierpaoli, P. Lombardi, 2021, International journal of molecular sciences.

Distamycin analogues with improved sequence-specific DNA binding activities.

R. Gambari, P. Natali, P. Giacomini, 1994, Biochemical pharmacology.

Berberine acts as a natural inhibitor of Wnt/β-catenin signaling--identification of more active 13-arylalkyl derivatives.

K. Friedrich, O. Huber, P. Lombardi, 2013, BioFactors.

Synthesis and biological evaluation of novel NK‐1 tachykinin receptor antagonists: The use of cycloalkyl amino acids as a template

A. Sisto, C. Maggi, C. Goso, 1995, Biopolymers.

Synthesis of Aryl 2-Benzofuranyl and Aryl 2-Indolyl Carbinols of High Enantiomeric Purity via Palladium-Catalyzed Heteroannulation of Chiral Arylpropargylic Alcohols.

M. Botta, V. Summa, F. Corelli, 1996 .

TOOLBOX: Strep-Tagged nano-assemblies of antibody-drug-conjugates (ADC) for modular and conditional cancer drugging

I. Manni, K. Friedrich, P. Giacomini, 2021, Oncology reports.

Enhanced Clearance of Neurotoxic Misfolded Proteins by the Natural Compound Berberine and Its Derivatives

V. Crippa, A. Poletti, M. Piccolella, 2020, International journal of molecular sciences.

Effect of new berberine derivatives on colon cancer cells.

A. Scovassi, L. M. Guamán Ortiz, P. Lombardi, 2015, Acta biochimica et biophysica Sinica.

New 13-pyridinealkyl berberine analogues intercalate to DNA and induce apoptosis in HepG2 and MCF-7 cells through ROS mediated p53 dependent pathway: biophysical, biochemical and molecular modeling studies

K. D. Saha, P. Lombardi, S. Chatterjee, 2015 .

Determination of absolute configuration of the derivative from 2-[4-(1-oxo-2-isoindolinyl)-phenyl]-propionic acid and R-(+)-1-phenylethylamine by 1H-NMR spectroscopy; use of shift reagent with diastereoisomeric amides

A. Longo, G. Marazzi, P. Lombardi, 1980 .

The Irreversible Inhibition of Aromatase (Oestrogen Synthetase) by Steroidal Compounds

P. Lombardi, 1995, Current Pharmaceutical Design.

Sludge bed development in denitrifying reactors using different inocula-performance and microbiological aspects.

L. Borzacconi, C. Etchebehere, P. Lombardi, 2002, Water Science and Technology.

N-formimidoyl analogues of distamycin

M. Dentini, G. Giannini, E. Monteagudo, 1996 .

Targeting human telomeric DNA quadruplex with novel berberrubine derivatives: insights from spectroscopic and docking studies

P. Lombardi, Suman Das, Sutanwi Bhuiya, 2019, Journal of biomolecular structure & dynamics.

Biochemical and pharmacological activity of novel 8-fluoroanthracyclines: influence of stereochemistry and conformation.

F. Zunino, G. Capranico, R. Supino, 1996, Molecular pharmacology.

TOOLBOX: Strep‑Tagged nano‑assemblies of antibody‑drug‑conjugates (ADC) for modular and conditional cancer drugging Corrigendum in /10.3892/or.2021.8110.

I. Manni, K. Friedrich, P. Giacomini, 2021, Oncology reports.