Hyuck Jin Lee

发表

Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis in the Last Decade.

M. G. Savelieff, Geewoo Nam, Juhye Kang, 2018, Chemical reviews.

Strategic Design of 2,2'-Bipyridine Derivatives to Modulate Metal-Amyloid-β Aggregation.

Cheol‐Min Park, Shin Jung C. Lee, Geewoo Nam, 2017, Inorganic chemistry.

Potent therapeutic targets for treatment of Alzheimer's disease: Amyloid degrading enzymes

Hyuck Jin Lee, E. Park, Hang Choi, 2021, Bulletin of the Korean Chemical Society.

Mechanistic approaches for chemically modifying the coordination sphere of copper–amyloid-β complexes

Jiyeon Han, Geewoo Nam, Hyuck Jin Lee, 2020, Proceedings of the National Academy of Sciences.

Monitoring metal–amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening† †Electronic supplementary information (ESI) available: Experimental section, Table S1, and Fig. S1–S10. See DOI: 10.1039/c8sc04943b

Sang J. Chung, Juhye Kang, Hyuck Jin Lee, 2018, Chemical science.

Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer's Disease.

Thomas J. Paul, B. Ruotolo, A. Ramamoorthy, 2017, Chemistry.

The Effects of Redox-Active Metal Ions and Amyloid-Degrading Enzymes on the Pathology of Alzheimer's Disease

Hyuck Jin Lee, Namdoo Kim, 2021, Prime Archives in Molecular Sciences.

An Iridium(III) Complex as a Photoactivatable Tool for Oxidation of Amyloidogenic Peptides with Subsequent Modulation of Peptide Aggregation.

A. Ramamoorthy, Hyun-Woo Rhee, Tae‐Hyuk Kwon, 2017, Chemistry.

Tuning Structures and Properties for Developing Novel Chemical Tools toward Distinct Pathogenic Elements in Alzheimer's Disease.

Jiyeon Han, Hyuck Jin Lee, M. Lim, 2017, ACS chemical neuroscience.

Sang J. Chung, Juhye Kang, Hyuck Jin Lee, 2018, Chemical science.

Cholesterol and metal ions in Alzheimer's disease.

Jeffrey S Derrick, Hyuck Jin Lee, M. Lim, 2014, Chemical Society reviews.

Chemical strategies to modify amyloidogenic peptides using iridium(iii) complexes: coordination and photo-induced oxidation† †Electronic supplementary information (ESI) available: Experimental section and Fig. S1–S19. See DOI: 10.1039/c9sc00931k

Hyun-Woo Rhee, Tae‐Hyuk Kwon, Geewoo Nam, 2019, Chemical science.

Interaction and reactivity of synthetic aminoisoflavones with metal-free and metal-associated amyloid-β

J. Brender, G. Balboni, A. Ramamoorthy, 2014 .

Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease.

Sanghyun Lee, Jin Hoon Kim, Cheal Kim, 2014, Journal of the American Chemical Society.

Impact of sphingosine and acetylsphingosines on the aggregation and toxicity of metal-free and metal-treated amyloid-β

Jiyeon Han, Geewoo Nam, Hyuck Jin Lee, 2020, Chemical science.

A near-infrared fluorescent probe for amyloid-β aggregates

Jinheung Kim, Hyuck Jin Lee, Misun Lee, 2019, Dyes and Pigments.

Metal Complexes as Promising Matrix Metalloproteinases Regulators

Hyuck Jin Lee, N. Kim, Yen Thi Minh Nguyen, 2023, International journal of molecular sciences.

Multiple reactivities of flavonoids towards pathological elements in Alzheimer's disease: structure–activity relationship†

M. Baik, Geewoo Nam, Juhye Kang, 2020, Chemical science.

Molecular Insights into Human Serum Albumin as a Receptor of Amyloid-β in the Extracellular Region.

Tae Su Choi, Hugh Inkon Kim, Hyuck Jin Lee, 2017, Journal of the American Chemical Society.

Redox-Active Metal Ions and Amyloid-Degrading Enzymes in Alzheimer’s Disease

Hyuck Jin Lee, Namdoo Kim, 2021, International journal of molecular sciences.

Target Enzymes Considered for the Treatment of Alzheimer's Disease and Parkinson's Disease

Hyuck Jin Lee, Namdoo Kim, 2020, BioMed research international.

Orobol: An Isoflavone with Regulatory Multifunctionality against Four Pathological Factors of Alzheimer's Disease.

Geewoo Nam, Juhye Kang, Hyuck Jin Lee, 2019, ACS chemical neuroscience.

Calprotectin influences the aggregation of metal-free and metal-bound amyloid-β by direct interaction.

Elizabeth M. Nolan, M. G. Savelieff, Juhye Kang, 2018, Metallomics : integrated biometal science.

Towards an understanding of amyloid-β oligomers: characterization, toxicity mechanisms, and inhibitors.

M. G. Savelieff, Hyuck Jin Lee, M. Lim, 2017, Chemical Society reviews.

Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation

Jeeyeon Lee, B. Ruotolo, A. Ramamoorthy, 2016 .

A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms.

Jeffrey S Derrick, Edward J Merino, B. Ruotolo, 2015, Journal of the American Chemical Society.

Inhibitory Activity Of Curcumin Derivatives Towards Metal-free And Metal-induced Amyloid-β Aggregation.

M. Allen, Hyuck Jin Lee, M. Lim, 2015, Current Alzheimer research.

A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-β implicated in Alzheimer's disease.

A. Ramamoorthy, M. G. Savelieff, Hyuck Jin Lee, 2014, Chemical communications.

Tailoring Hydrophobic Interactions between Probes and Amyloid-β Peptides for Fluorescent Monitoring of Amyloid-β Aggregation

Hyuck Jin Lee, M. Lim, Jaeheung Cho, 2018, ACS omega.

Aconitine Neurotoxicity According to Administration Methods

Hyuck Jin Lee, Byoung-Soo Shin, Seung Jae Lee, 2021, Journal of clinical medicine.

Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β Species.

J. Brender, G. Balboni, A. Ramamoorthy, 2014, Chemical science.

Minimalistic Design Approach for Multi-Reactivity against Free Radicals and Metal-Free and Metal-Bound Amyloid-β Peptides: Redox-Based Substitutions of Benzene

Geewoo Nam, Juhye Kang, Hyuck Jin Lee, 2019 .

Hyun-Woo Rhee, Tae‐Hyuk Kwon, Geewoo Nam, 2019, Chemical Science.

Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis in the Last Decade.

M. G. Savelieff, Geewoo Nam, Juhye Kang, 2018, Chemical reviews.

Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease.

Jeffrey S Derrick, J. Brender, M. Bowers, 2014, Journal of the American Chemical Society.

Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia.

Jiyeon Han, M. Baik, S. Oh, 2020, Journal of the American Chemical Society.