B. Shimpukade

发表

The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

B. Hudson, G. Milligan, A. Tobin, 2013, Molecular Pharmacology.

The Molecular Basis of Ligand Interaction at Free Fatty Acid Receptor 4 (FFA4/GPR120)*

B. Hudson, G. Milligan, B. Shimpukade, 2014, The Journal of Biological Chemistry.

Concomitant Action of Structural Elements and Receptor Phosphorylation Determines Arrestin-3 Interaction with the Free Fatty Acid Receptor FFA4*

B. Hudson, G. Milligan, A. Tobin, 2014, The Journal of Biological Chemistry.

The pharmacology of a potent and selective agonist, TUG-891, demonstrates both potential opportunity and possible challenges to therapeutic agonism of FFA4 (GPR120)

B. Hudson, G. Milligan, A. Tobin, 2013 .

Preview : Published ahead of advance online publication Treatment with TUG 891 , a free fatty acid receptor 4 agonist , restores adipose tissue metabolic dysfunction following chronic sleep fragmentation in mice

D. Gozal, I. Almendros, B. Shimpukade, 2016 .

Novel GPR120 agonist TUG891 modulates fat taste perception and preference and activates tongue-brain-gut axis in mice

A. Hichami, N. Khan, B. Murtaza, 2019, Journal of Lipid Research.

Discovery of a potent and selective GPR120 agonist.

B. Hudson, G. Milligan, B. Shimpukade, 2012, Journal of medicinal chemistry.

An efficient synthesis of (7S,10R)-2-bromo-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]indole: application in the preparation and structural confirmation of a potent 5-HT6 antagonist

M. M. Hsia, K. Nacro, B. Shimpukade, 2012 .

A concise synthesis of the potent inflammatory mediator 5-oxo-ETE

E. Kostenis, Stefanie Blättermann, B. Shimpukade, 2012 .

Complex Pharmacology of Free Fatty Acid Receptors.

B. Hudson, G. Milligan, B. Shimpukade, 2017, Chemical reviews.

Syddansk Universitet Complex Pharmacology of Free Fatty Acid Receptors

B. Hudson, G. Milligan, B. Shimpukade, 2017 .

The GPR120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat

A. R. Miller, M. Christian, S. Damak, 2018, EMBO molecular medicine.

Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity.

B. Hudson, G. Milligan, B. Shimpukade, 2016, Journal of medicinal chemistry.

Free fatty acid receptors, FFAR1 and FFAR4, are novel bronchodilator targets in mouse and human precision-cut lung slices

C. Donovan, S. Royce, J. Bourke, 2018, Airway pharmacology and treatment.

Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy.

Christer S. Ejsing, B. Hudson, G. Milligan, 2016, Journal of Medicinal Chemistry.