S. Kirincich

发表

Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site.

A. Moretto, D. Joseph-McCarthy, T. Mansour, 2007, Journal of medicinal chemistry.

Benzhydrylquinazolinediones: novel cytosolic phospholipase A2alpha inhibitors with improved physicochemical properties.

J. D. Clark, J. McKew, J. Xiang, 2009, Bioorganic & medicinal chemistry.

Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.

J. D. Clark, M. Hegen, J. McKew, 2008, Journal of medicinal chemistry.

Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.

A. Moretto, D. Joseph-McCarthy, D. P. Wilson, 2006, Bioorganic & medicinal chemistry.

An Efficient Preparation and Selected Birch Reduction−Alkylations of 3,4-Dihydro-4,5-dialkyl-2-benzopyran-1-ones

S. Kirincich, A. Schultz, 1996 .

Regio‐ and stereochemistry of the photo‐ring contraction of 4‐pyrones

S. Kirincich, J. Pavlik, R. Pires, 1991 .

Probing acid replacements of thiophene PTP1B inhibitors.

D. Joseph-McCarthy, M. Tam, Weixin Xu, 2007, Bioorganic & medicinal chemistry letters.

An Efficient Preparation and Selected Birch Reduction‐Alkylations of 3, 4‐Dihydro‐4,5‐dialkyl‐2‐benzopyran‐1‐ones.

S. Kirincich, A. Schultz, 1996 .

An Improved Synthetic Preparation of 3-Butenal

M. Crimmins, S. Kirincich, A. Wells, 1998 .

An aldol approach to the synthesis of the EF fragment of spongistatin 1.

M. Crimmins, S. Kirincich, J. Katz, 2001, Organic letters.

Asymmetric organic synthesis. Preparation and birch reduction-alkylation of 2-methyl-3,4-dihydroisoquinolin-1-ones

S. Kirincich, R. Rahm, A. Schultz, 1995 .

An enzyme-linked immunosorbent assay to measure insulin receptor dephosphorylation by PTP1B.

M. Tam, Zhao‐Kui Wan, S. Kirincich, 2007, Analytical biochemistry.

Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).

K. Parris, J. Telliez, F. Lovering, 2009, Bioorganic & medicinal chemistry.

Molecular activation of PPARγ by angiotensin II type 1-receptor antagonists

S. Kirincich, Yan-ling Zhang, D. Erbe, 2006 .

Asymmetric Total Synthesis of the Caribbean Fruit Fly Pheromone (+)-Epianastrephin

S. Kirincich, A. Schultz, 1996 .

Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α2α

S. Khor, J. D. Clark, J. McKew, 2007 .

Discovery of Ecopladib, an indole inhibitor of cytosolic phospholipase A2alpha.

S. Khor, J. McKew, M. S. Ku, 2007, Journal of medicinal chemistry.

Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists.

S. Kirincich, Yan-ling Zhang, D. Erbe, 2006, Vascular pharmacology.

Structure‐Based Optimization of Protein Tyrosine Phosphatase‐1 B Inhibitors: Capturing Interactions with Arginine 24

Wei Li, A. Moretto, D. Joseph-McCarthy, 2008, ChemMedChem.

Prodrug delivery of novel PTP1B inhibitors to enhance insulin signalling

L. Klaman, Zhao‐Kui Wan, S. Kirincich, 2009, Diabetes, obesity & metabolism.