J. Dunn

发表

Discovery of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (pamapimod) and 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as orally bioavailable and highly selective inhibitors

B. Graves, A. Kuglstatter, M. Stahl, 2011, Journal of medicinal chemistry.

De novo fragment design: a medicinal chemistry approach to fragment-based lead generation.

A. M. Giannetti, S. Harris, J. D. de Vicente, 2013, Journal of medicinal chemistry.

Discovery of S-[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]methanone (RO3201195), an orally bioavailable and highly selective inhibitor of p38 MAP kinase.

D. Rotstein, C. Ramesha, M. Browner, 2006, Journal of medicinal chemistry.

Pharmacological activity of amantadine: effect of N‐alkyl substitution

J. Dunn, G. Gianutsos, J. Henkel, 1986, The Journal of pharmacy and pharmacology.

Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): optimization for JNK potency and physicochemical properties.

A. Kuglstatter, Brian R. Wong, J. D. Dal Porto, 2013, Bioorganic & medicinal chemistry letters.

Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase.

Y. Li, W. Huber, T. Mirzadegan, 2008, Bioorganic & medicinal chemistry letters.

Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase.

Yu Li, Andrew Briggs, Klaus Klumpp, 2008, Bioorganic & medicinal chemistry letters.

Orally bioavailable prodrugs of a BCS class 2 molecule, an inhibitor of HIV-1 reverse transcriptase.

D. Stefanidis, J. Dunn, Amy S. Zhou, 2008, Bioorganic & medicinal chemistry letters.

Analgetic and antiinflammatory 7-aroylbenzofuran-5-ylacetic acids and 7-aroylbenzothiophene-5-ylacetic acids.

J. Dunn, A. Tomolonis, N. Ackerman, 1986, Journal of Medicinal Chemistry.

Preformulation Prodrug Research - Chemical and Enzymatic Hydrolysis Kinetics of the Glycerol, Glycolic Acid and Morpholino Ethyl Ester Derivatives of a Developmental Analgesic Agent (RS-82917)

J. Dunn, L. Gu, C. Dvorak, 1989 .

Analgetic and Antiinflammatory 7-Aroylbenzofuran-5-ylacetic Acids and 7-Aroylbenzothiophen-5-ylacetic Acids.

J. Dunn, A. Tomolonis, N. Ackerman, 1987 .

Dibenzotropone- and dibenzosuberonecarboxylic acids with bronchodilator activity.

J. Dunn, J. Pfister, D. Green, 1979, Journal of medicinal chemistry.

Pharmacological changes in dopaminergic systems induced by long-term administration of amantadine.

J. Dunn, G. Gianutsos, S. Chute, 1985, European journal of pharmacology.

Antiinflammatory and aldose reductase inhibitory activity of some tricyclic arylacetic acids.

L. Waterbury, J. Dunn, P. Nelson, 1986, Journal of medicinal chemistry.

Development of amino-pyrimidine inhibitors of c-Jun N-terminal kinase (JNK): kinase profiling guided optimization of a 1,2,3-benzotriazole lead.

Johannes C. Hermann, C. Lukacs, A. Kuglstatter, 2013, Bioorganic & medicinal chemistry letters.

Isotachophoretic Studies of Adenosine Phosphates and Divalent Cations of Perfused Mouse Liver Cells

J. Dunn, R. Kemp, 1975 .

Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): optimization for JNK potency and physicochemical properties.

A. Kuglstatter, Brian R. Wong, J. D. Dal Porto, 2013, Bioorganic & medicinal chemistry letters.